| 1 | AHNAK, CACNB2
|
| Ahnak1 interaction is affected by phosphorylation of Ser-296 on Cavβ₂.
|
| Pankonien I, Otto A, Dascal N, Morano I, Haase H.
|
| Biochem Biophys Res Commun 421(2):184-9. doi: 10.1016/j.bbrc.2012.03.132. Epub 2012 Apr 4.
2012
|
| 2 | ATP2B1, CACNB2, CASZ1, CNNM2, CSK, CYP17A1, EFCAB1, FGF5, ITGA9, MTHFR, PLEKHA7, ULK3
|
| Blood pressure and hypertension are associated with 7 loci in the Japanese population.
|
| Takeuchi F, Isono M, Katsuya T, Yamamoto K, Yokota M, Sugiyama T, Nabika T, Fujioka A, Ohnaka K, Asano H, Yamori Y, Yamaguchi S, Kobayashi S, Takayanagi R, Ogihara T, Kato N.
|
| Circulation 121(21):2302-9. Epub 2010 May 17. 2010
|
| 3 | CACNB1, CACNB2, CAMK2A
|
| CaMKII associates with CaV1.2 L-type calcium channels via selected beta subunits to enhance regulatory phosphorylation.
|
| Abiria SA, Colbran RJ.
|
| J Neurochem 112(1):150-61. Epub 2009 Oct 15.
2010
|
| 4 | CACNB2
|
| The Ca2+ channel subunit beta2 regulates Ca2+ channel abundance and function in inner hair cells and is required for hearing.
|
| Neef J, Gehrt A, Bulankina AV, Meyer AC, Riedel D, Gregg RG, Strenzke N, Moser T.
|
| J Neurosci 29(34):10730-40.
2009
|
| 5 | BRGS4, CACNB2
|
| Accelerated inactivation of the L-type calcium current due to a mutation in CACNB2b underlies Brugada syndrome.
|
| Cordeiro JM, Marieb M, Pfeiffer R, Calloe K, Burashnikov E, Antzelevitch C.
|
| J Mol Cell Cardiol 46(5):695-703.
2009
|
| 6 | CACNB2
|
| Role of CaVbeta subunits, and lack of functional reserve, in protein kinase A modulation of cardiac CaV1.2 channels.
|
| Miriyala J, Nguyen T, Yue DT, Colecraft HM.
|
| Circ Res 102(7):e54-64. Epub 2008 Mar 20.
2008
|
| 7 | CACNB2
|
| Loss-of-function mutations in the cardiac calcium channel underlie a new clinical entity characterized by ST-segment elevation, short QT intervals, and sudden cardiac death.
|
| Antzelevitch C, Pollevick GD, Cordeiro JM, Casis O, Sanguinetti MC, Aizawa Y, Guerchicoff A, Pfeiffer R, Oliva A, Wollnik B, Gelber P, Bonaros EP Jr, Burashnikov E, Wu Y, Sargent JD, Schickel S, Oberheiden R, Bhatia A, Hsu LF, Haïssaguerre M, Schimpf R, Borggrefe M, Wolpert C.
|
| Circulation 115(4):442-9. Epub 2007 Jan 15.
2007
|
| 8 | CACNB2, RRAD
|
| Dominant negative suppression of Rad leads to QT prolongation and causes ventricular arrhythmias via modulation of L-type Ca2+ channels in the heart.
|
| Yada H, Murata M, Shimoda K, Yuasa S, Kawaguchi H, Ieda M, Adachi T, Murata M, Ogawa S, Fukuda K.
|
| Circ Res 101(1):69-77. Epub 2007 May 24.
2007
|
| 9 | CACNB2
|
| Protein kinase G phosphorylates Cav1.2 alpha1c and beta2 subunits.
|
| Yang L, Liu G, Zakharov SI, Bellinger AM, Mongillo M, Marx SO.
|
| Circ Res 101(5):465-74. Epub 2007 Jul 12.
2007
|
| 10 | CACNB2
|
| L-type Ca2+ channel facilitation mediated by phosphorylation of the beta subunit by CaMKII.
|
| Grueter CE, Abiria SA, Dzhura I, Wu Y, Ham AJ, Mohler PJ, Anderson ME, Colbran RJ.
|
| Mol Cell 23(5):641-50.
2006
|
| 11 | CACNB2
|
| Molecular heterogeneity of calcium channel beta-subunits in canine and human heart: evidence for differential subcellular localization.
|
| Foell JD, Balijepalli RC, Delisle BP, Yunker AM, Robia SL, Walker JW, McEnery MW, January CT, Kamp TJ.
|
| Physiol Genomics 17(2):183-200. 2004
|
| 12 | CACNB2
|
| Identification of the sites phosphorylated by cyclic AMP-dependent protein kinase on the beta 2 subunit of L-type voltage-dependent calcium channels.
|
| Gerhardstein BL, Puri TS, Chien AJ, Hosey MM.
|
| Biochemistry 38(32):10361-70.
1999
|
| 13 | CACNB2, CACNB4
|
| Assignment of human genes for beta2 and beta4 subunits of voltage-dependent Ca2+ channels to chromosomes 10p12 and 2q22-q23.
|
| Taviaux S, Williams ME, Harpold MM, Nargeot J, Lory P.
|
| Hum Genet 100(2):151-4. 1997
|
| 14 | CACNB2
|
| Autoimmunity to the voltage-gated calcium channel underlies the Lambert-Eaton myasthenic syndrome, a paraneoplastic disorder.
|
| Vincent A, et al.
|
| Trends Neurosci 12 : 496-502. 1989
|