| 1 | C8A, C8B, C8G
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| Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.
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| Lovelace LL, Cooper CL, Sodetz JM, Lebioda L.
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| J Biol Chem 286(20):17585-92. Epub 2011 Mar 25.
2011
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| 2 | C8A, C8B, C8G
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| Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit.
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| Slade DJ, Lovelace LL, Chruszcz M, Minor W, Lebioda L, Sodetz JM.
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| J Mol Biol 379(2):331-42. Epub 2008 Apr 3.
2008
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| 3 | C8A, C8B, C8G, C9
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| Functional studies of the MACPF domain of human complement protein C8alpha reveal sites for simultaneous binding of C8beta, C8gamma, and C9.
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| Slade DJ, Chiswell B, Sodetz JM.
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| Biochemistry 45(16):5290-6. 2006
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| 4 | C8A, C8B, C8G
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| Role of the human C8 subunits in complement-mediated bacterial killing: evidence that C8 gamma is not essential.
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| Parker CL, Sodetz JM.
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| Mol Immunol 39(7-8):453-8. 2002
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| 5 | C8A, C8B, C8G
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| Interaction between the C8 alpha-gamma and C8 beta subunits of human complement C8: role of the C8 beta N-terminal thrombospondin type 1 module and membrane attack complex/perforin domain.
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| Musingarimi P, Plumb ME, Sodetz JM.
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| Biochemistry 41(37):11255-60. 2002
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| 6 | C8A, C8B, C8G
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| An indel within the C8 alpha subunit of human complement C8 mediates intracellular binding of C8 gamma and formation of C8 alpha-gamma.
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| Plumb ME, Sodetz JM.
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| Biochemistry 39(42):13078-83. 2000
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| 7 | C8A, C8B
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| Physical linkage and orientation of the human complement C8alpha and C8beta genes on chromosome 1p32.
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| Platteborze PL, et al.
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| Hum Genet 98 : 443-446. 1996
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| 8 | C8A, C8B
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| Genomic organization of human complement protein C8alpha and further examination of its linkage to C8beta.
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| Michelotti GA, et al.
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| Hum Genet 95 : 513-518. 1995
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| 9 | C8A, C8B
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| Regional chromosomal assignment of genes encoding the alpha and beta subunits of human complement protein C8 to 1p32.
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| Theriault A, et al.
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| Hum Genet 88 : 703-704. 1992
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| 10 | C8A, C8B
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| Linkage and association studies with C8A and C8B RFLPs on chromosome 1.
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| Rogde S, et al.
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| Ann Hum Genet 56 : 233-242. 1992
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| 11 | C8B
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| Two distinct abnormalities in patients with C8 alpha-gamma deficiency. Low level of C8-beta chain and presence of dysfunctional C8 alpha-gamma subunit.
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| Tedesco F, et al.
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| J Clin Invest 86 : 884-888. 1990
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| 12 | C8B
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| A BamH1 RFLP of the C8B gene.
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| Rogde S, et al.
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| Nucleic Acids Res 17 : 6760. 1989
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| 13 | C8A, C8B
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| Evidence of close physical linkage between loci encoding human complement proteins C8-alpha and C8-beta.
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| Snider JV, et al.
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| FASEB J 3 : A802. 1989
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| 14 | C8A, C8B, C8G
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| Chromosomal assignment of genes encoding the alpha, beta, and gamma subunits of human complement protein C8 : identification of a close physical linkage between the alpha and the beta loci.
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| Kaufman KM, et al.
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| Genomics 5 : 475-480. 1989
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| 15 | C8A, C8B, C8G
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| The eighth component of human complement (C8): Evidence that it is an oligomeric serum protein assembled from products of three different genes.
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| Ng SC, Rao AG, Howard OM, Sodetz JM.
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| Biochemistry 26 : 5229-5233. 1987
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| 16 | C8B
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| Dysfunctional C8-beta chain in patients with C8 deficiency.
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| Tschopp JF, et al.
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| Scand J Immunol 24 : 715-720. 1986
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| 17 | C8A, C8B
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| The C8A and C8B loci are closely linked on chromosome 1.
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| Rogde S, et al.
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| Ann Hum Genet 50 : 139-144. 1986
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| 18 | C8B
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| Two complement component C8 loci are localized between PGM1 and RH onchromosome 1.
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| Rogde S, et al.
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| (HGM8) Cytogenet Cell Genet 40 : 734-735. 1985
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