1 | C5
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| Structure, function and control of complement C5 and its proteolytic fragments.
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| Laursen NS, Magnani F, Gottfredsen RH, Petersen SV, Andersen GR.
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| Curr Mol Med 12(8):1083-97. Review.
2012
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2 | C5
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| Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression.
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| Corrales L, Ajona D, Rafail S, Lasarte JJ, Riezu-Boj JI, Lambris JD, Rouzaut A, Pajares MJ, Montuenga LM, Pio R.
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| J Immunol 189(9):4674-83. doi: 10.4049/jimmunol.1201654. Epub 2012 Oct 1.
2012
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3 | C5
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| Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway.
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| Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM.
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| Blood 120(8):1717-25. doi: 10.1182/blood-2012-02-412080. Epub 2012 Jul 16.
2012
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4 | C5
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| Polymorphism of the complement 5 gene and cardiovascular outcome in patients with atherosclerosis.
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| Hoke M, Speidl W, Schillinger M, Minar E, Zehetmayer S, Schönherr M, Wagner O, Mannhalter C.
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| Eur J Clin Invest 42(9):921-6. doi: 10.1111/j.1365-2362.2012.02669.x. Epub 2012 Mar 27.
2012
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5 | C5
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| Complement component 5 contributes to poor disease outcome in humans and mice with pneumococcal meningitis.
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| Woehrl B, Brouwer MC, Murr C, Heckenberg SG, Baas F, Pfister HW, Zwinderman AH, Morgan BP, Barnum SR, van der Ende A, Koedel U, van de Beek D.
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| J Clin Invest 121(10):3943-53. doi: 10.1172/JCI57522. Epub 2011 Sep 19.
2011
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6 | C5
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| The complement component C5a is present in human coronary lesions in vivo and induces the expression of MMP-1 and MMP-9 in human macrophages in vitro.
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| Speidl WS, Kastl SP, Hutter R, Katsaros KM, Kaun C, Bauriedel G, Maurer G, Huber K, Badimon JJ, Wojta J.
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| FASEB J 25(1):35-44. doi: 10.1096/fj.10-156083. Epub 2010 Sep 2.
2011
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7 | C5
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| Single nucleotide polymorphisms of complement component 5 and periodontitis.
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| Chai L, Song YQ, Zee KY, Leung WK.
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| J Periodontal Res 45(3):301-8. doi: 10.1111/j.1600-0765.2009.01234.x. Epub 2009 Nov 9.
2010
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8 | C5, TRAF1
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| Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis.
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| Patsopoulos NA, Ioannidis JP.
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| Ann Rheum Dis nn Rheum Dis. 2009 May 15. [Epub ahead of print]
2009
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9 | C5, TRAF1
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| TRAF1-C5 as a risk locus for rheumatoid arthritis--a genomewide study.
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| Plenge RM, Seielstad M, Padyukov L, Lee AT, Remmers EF, Ding B, Liew A, Khalili H, Chandrasekaran A, Davies LR, Li W, Tan AK, Bonnard C, Ong RT, Thalamuthu A, Pettersson S, Liu C, Tian C, Chen WV, Carulli JP, Beckman EM, Altshuler D, Alfredsson L, Criswell LA, Amos CI, Seldin MF, Kastner DL, Klareskog L, Gregersen PK.
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| N Engl J Med 357(12):1199-209. Epub 2007 Sep 5.
2007
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10 | C5, TRAF1
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| A candidate gene approach identifies the TRAF1/C5 region as a risk factor for rheumatoid arthritis.
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| Kurreeman FA, Padyukov L, Marques RB, Schrodi SJ, Seddighzadeh M, Stoeken-Rijsbergen G, van der Helm-van Mil AH, Allaart CF, Verduyn W, Houwing-Duistermaat J, Alfredsson L, Begovich AB, Klareskog L, Huizinga TW, Toes RE.
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| PLoS Med 4(9):e278. Erratum in: PLoS Med. 2007 Dec;4(12):e358.
2007
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11 | C5
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| Complement factor 5 is a quantitative trait gene that modifies liver fibrogenesis in mice and humans.
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| Hillebrandt S, Wasmuth HE, Weiskirchen R, Hellerbrand C, Keppeler H, Werth A, Schirin-Sokhan R, Wilkens G, Geier A, Lorenzen J, Kohl J, Gressner AM, Matern S, Lammert F.
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| Nat Genet 37(8):835-43. Epub 2005 Jul 3. 2005
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12 | C5, C7
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| Recombinant C345C and factor I modules of complement components C5 and C7 inhibit C7 incorporation into the complement membrane attack complex.
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| Thai CT, Ogata RT.
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| J Immunol 174(10):6227-32. 2005
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13 | C5, C5AR1
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| Structure-function relationships of human C5a and C5aR.
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| Huber-Lang MS, Sarma JV, McGuire SR, Lu KT, Padgaonkar VA, Younkin EM, Guo RF, Weber CH, Zuiderweg ER, Zetoune FS, Ward PA.
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| J Immunol 170(12):6115-24. 2003
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14 | C5
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| The assignment of the human gene coding for complement C5 to chromosome 9q22-9q33.
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| Jeremiah SJ, et al.
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| Ann Hum Genet 52 : 111-116. 1988
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15 | C5
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| Assignment of human complement component C5 to chromosome 9.
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| Jeremiah SJ, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 634. 1987
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16 | C5
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| Chromosomal mapping of the gene encoding the fifth component of human complement.
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| Lemons RS, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 647. 1987
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