1 | C3CER1, LIMD1, TSG3B
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| The chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development.
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| Sharp TV, Al-Attar A, Foxler DE, Ding L, de A Vallim TQ, Zhang Y, Nijmeh HS, Webb TM, Nicholson AG, Zhang Q, Kraja A, Spendlove I, Osborne J, Mardis E, Longmore GD.
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| Proc Natl Acad Sci U S A 105(50):19932-7. Epub 2008 Dec 5.
2008
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2 | ZNF501, ZNF502, TMEM158, SACM1L, SLC6A20, CLEC3B, FYCO1, C3CER1
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| Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the elimination test.
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| Darai E, Kost-Alimova M, Kiss H, Kansoul H, Klein G, Imreh S.
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| Genomics 86(1):1-12. 2005
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3 | C3CER1
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| Interstitial deletions including chromosome 3 common eliminated region 1 (C3CER1) prevail in human solid tumors from 10 different tissues.
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| Petursdottir TE, Thorsteinsdottir U, Jonasson JG, Moller PH, Huiping C, Bjornsson J, Egilsson V, Imreh S, Ingvarsson S.
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| Genes Chromosomes Cancer 41(3):232-42. 2004
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4 | C3CER1, CCR1, CCR2, CCR3, CCR4, CCR5, LTF
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| A 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors.
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| Yang Y, Kiss H, Kost-Alimova M, Kedra D, Fransson I, Seroussi E, Li J, Szeles A, Kholodnyuk I, Imreh MP, Fodor K, Hadlaczky G, Klein G, Dumanski JP, Imreh S.
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| Genomics 62(2):147-55. 1999
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5 | TSG3B, C3CER1
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| Human/mouse microcell hybrid based elimination test reduces the putative tumor suppressor region at 3p21.3 to 1.6 cM.
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| Szeles A, et al.
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| Genes Chromosomes Cancer 20(4):329-36 1997
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6 | C3CER1
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| A 3p21.3 region is preferentially eliminated from human chromosome 3/mouse microcell hybrids during tumor growth in SCID mice.
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| Kholodnyuk I, et al.
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| Genes Chromosomes Cancer 18(3):200-11 1997
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