1 | C1QA, C1R, C1S
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| C1q protein binds to the apoptotic nucleolus and causes C1 protease degradation of nucleolar proteins.
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| Cai Y, Teo BH, Yeo JG, Lu J.
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| J Biol Chem 290(37):22570-80. doi: 10.1074/jbc.M115.670661.
2015
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2 | C1QA, C1R, C1S
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| Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites.
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| Bally I, Ancelet S, Moriscot C, Gonnet F, Mantovani A, Daniel R, Schoehn G, Arlaud GJ, Thielens NM.
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| Proc Natl Acad Sci U S A 110(21):8650-5. doi: 10.1073/pnas.1304894110.
2013
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3 | AGER, C1QA, C1QB, C1QC
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| RAGE binds C1q and enhances C1q-mediated phagocytosis.
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| Ma W, Rai V, Hudson BI, Song F, Schmidt AM, Barile GR.
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| Cell Immunol 274(1-2):72-82. doi: 10.1016/j.cellimm.2012.02.001. Epub 2012 Feb 13.
2012
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4 | C1QA
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| C1q enhances cone photoreceptor survival in a mouse model of autosomal recessive retinitis pigmentosa.
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| Humphries MM, Kenna PF, Campbell M, Tam LC, Nguyen AT, Farrar GJ, Botto M, Kiang AS, Humphries P.
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| Eur J Hum Genet 20(1):64-8. doi: 10.1038/ejhg.2011.151. Epub 2011 Aug 24.
2012
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5 | C1QA
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| Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.
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| Naito AT, Sumida T, Nomura S, Liu ML, Higo T, Nakagawa A, Okada K, Sakai T, Hashimoto A, Hara Y, Shimizu I, Zhu W, Toko H, Katada A, Akazawa H, Oka T, Lee JK, Minamino T, Nagai T, Walsh K, Kikuchi A, Matsumoto M, Botto M, Shiojima I, Komuro I.
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| Cell 149(6):1298-313. doi: 10.1016/j.cell.2012.03.047. Erratum in: Cell. 2012 Aug 3;150(3):659-60.
2012
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6 | C1QA
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| The complement C1qA enhances retinoic acid-inducible gene-I-mediated immune signalling.
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| Wang Y, Tong X, Zhang J, Ye X.
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| Immunology 136(1):78-85. doi: 10.1111/j.1365-2567.2012.03561.x.
2012
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7 | C1QA
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| Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency.
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| Namjou B, Keddache M, Fletcher D, Dillon S, Kottyan L, Wiley G, Gaffney PM, Wakeland BE, Liang C, Wakeland EK, Scofield RH, Kaufman K, Harley JB.
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| Lupus 21(10):1113-8. doi: 10.1177/0961203312443993. Epub 2012 Apr 3.
2012
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8 | C1QA
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| C1q regulation of dendritic cell development from monocytes with distinct cytokine production and T cell stimulation.
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| Teh BK, Yeo JG, Chern LM, Lu J.
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| Mol Immunol 48(9-10):1128-38. doi: 10.1016/j.molimm.2011.02.006. Epub 2011 Mar 22.
2011
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9 | C1QA
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| Assessing association of common variation in the C1Q gene cluster with systemic lupus erythematosus.
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| Rafiq S, Frayling TM, Vyse TJ, Cunninghame Graham DS, Eggleton P.
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| Clin Exp Immunol 161(2):284-9. doi: 10.1111/j.1365-2249.2010.04185.x. Epub 2010 May 28.
2010
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10 | C1QA, PRNP
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| Complement protein C1q forms a complex with cytotoxic prion protein oligomers.
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| Erlich P, Dumestre-Pérard C, Ling WL, Lemaire-Vieille C, Schoehn G, Arlaud GJ, Thielens NM, Gagnon J, Cesbron JY.
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| J Biol Chem 285(25):19267-76. doi: 10.1074/jbc.M109.071860. Epub 2010 Apr 21.
2010
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11 | C1QA, C1R, C1S
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| Calcium-dependent conformational flexibility of a CUB domain controls activation of the complement serine protease C1r.
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| Major B, Kardos J, Kékesi KA, Lorincz Z, Závodszky P, Gál P.
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| J Biol Chem 285(16):11863-9. doi: 10.1074/jbc.M109.098541.
2010
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12 | C1QA, C1QB
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| Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met.
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| Dardiotis E, Koutsou P, Zamba-Papanicolaou E, Vonta I, Hadjivassiliou M, Hadjigeorgiou G, Cariolou M, Christodoulou K, Kyriakides T.
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| J Neurol Sci 284(1-2):158-62. Epub 2009 Jun 3. 2009
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13 | ARRB2, C1QA
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| Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival.
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| Lattin JE, Greenwood KP, Daly NL, Kelly G, Zidar DA, Clark RJ, Thomas WG, Kellie S, Craik DJ, Hume DA, Sweet MJ.
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| Mol Immunol 47(2-3):340-7. doi: 10.1016/j.molimm.2009.09.012. Epub 2009 Sep 26.
2009
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14 | C1QA, C1QB, C1QC
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| The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition.
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| Paďdassi H, Tacnet-Delorme P, Lunardi T, Arlaud GJ, Thielens NM, Frachet P.
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| FEBS Lett 582(20):3111-6. Epub 2008 Aug 12.
2008
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15 | C1QA
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| The classical complement cascade mediates CNS synapse elimination.
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| Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, Sher A, Litke AM, Lambris JD, Smith SJ, John SW, Barres BA.
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| Cell 131(6):1164-78. 2007
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16 | C1QA, C1QB, C1QC
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| Complement protein C1q induces maturation of human dendritic cells.
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| Csomor E, Bajtay Z, Sándor N, Kristóf K, Arlaud GJ, Thiel S, Erdei A.
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| Mol Immunol 44(13):3389-97. Epub 2007 Mar 26.
2007
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17 | C1QA
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| Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.
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| Kojouharova MS, Gadjeva MG, Tsacheva IG, Zlatarova A, Roumenina LT, Tchorbadjieva MI, Atanasov BP, Waters P, Urban BC, Sim RB, Reid KB, Kishore U.
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| J Immunol 172(7):4351-8. 2004
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18 | C1QA, C1QB, C1QC
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| Mutational analyses of the recombinant globular regions of human C1q A, B, and C chains suggest an essential role for arginine and histidine residues in the C1q-IgG interaction.
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| Kojouharova MS, Gadjeva MG, Tsacheva IG, Zlatarova A, Roumenina LT, Tchorbadjieva MI, Atanasov BP, Waters P, Urban BC, Sim RB, Reid KB, Kishore U.
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| J Immunol 172(7):4351-8.
2004
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19 | C1QA, C1QB, C1QC
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| C1q regulatory region polymorphism down-regulating murine c1q protein levels with linkage to lupus nephritis.
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| Miura-Shimura Y, Nakamura K, Ohtsuji M, Tomita H, Jiang Y, Abe M, Zhang D, Hamano Y, Tsuda H, Hashimoto H, Nishimura H, Taki S, Shirai T, Hirose S.
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| J Immunol 169(3):1334-9.
2002
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20 | C1QA
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| Molecular basis of hereditary C1q deficiency associated with SLE and IgA nephropathy in a Turkish family.
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| Topaloglu R, et al.
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| Kidney Int 50 : 635-642. 1996
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21 | C1QA, C1QC
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| Non-sense and missense mutations in the structural genes of complement component C1q A and C chains are linked with two different types of complete selective C1q deficiencies.
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| Petry F, et al.
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| J Immunol 155 : 4734-4738. 1995
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22 | C1Q@, C1QA, C1QB, C1QC
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| Localization of the gene cluster encoding the A,B, and C chains of human C1q to 1p34.1-1p36.3.
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| Sellar GC, et al.
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| Immunogenetics 35 : 214-216. 1992
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23 | C1Q@, C1QA, C1QB, C1QC
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| Characterization and organization of the genes encoding the A-, B-, and C-chains of human complement subcomponent C1q.
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| Sellar GC, et al.
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| Biochem J 274 : 481-490. 1991
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24 | C1QA
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| Assignment of the A chain of C1q (C1QA) to the short arm of chromosome 1.
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| Hedge PJ, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 627. 1987
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