1 | BTG4, CNOT7, CNOT8, ZCF1
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| Homozygous Mutations in BTG4 Cause Zygotic Cleavage Failure and Female Infertility
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| Zheng W, Zhou Z, Sha Q, Niu X, Sun X, Shi J, Zhao L, Zhang S, Dai J, Cai S, Meng F, Hu L, Gong F, Li X, Fu J, Shi R, Lu G, Chen B, Fan H, Wang L, Lin G, Sang Q.
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| Am J Hum Genet. Jul 2;107(1):24-33. doi: 10.1016/j.ajhg.2020.05.010. Epub 2020 Jun 4. 2020
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2 | BTG4
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| BTG4 is A Novel p53 Target Gene That Inhibits Cell Growth and Induces Apoptosis.
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| Zhang N, Jiang T, Wang Y, Wang S, Hu L, Bu Y.
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| Genes (Basel). Feb 19;11(2):217. doi: 10.3390/genes11020217 2020
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3 | BTG4, CNOT7, CNOT8
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| The BTG4 and CAF1 complex prevents the spontaneous activation of eggs by deadenylating maternal mRNAs.
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| Pasternak M, Pfender S, Santhanam B, Schuh M.
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| Open Biol. Sep;6(9):160184. doi: 10.1098/rsob.160184 2016
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4 | BTG4, CNOT7
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| BTG4 is a meiotic cell cycle-coupled maternal-zygotic-transition licensing factor in oocytes.
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| Yu C, Ji SY, Sha QQ, Dang Y, Zhou JJ, Zhang YL, Liu Y, Wang ZW, Hu B, Sun QY, Sun SC, Tang F, Fan HY.
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| Nat Struct Mol Biol. May;23(5):387-94. doi: 10.1038/nsmb.3204. Epub 2016 Apr 1 2016
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5 | BTG1, BTG2, BTG3, BTG4, CNOT7, CNOT8, TOB1, TOB2
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| The anti-proliferative activity of BTG/TOB proteins is mediated via the Caf1a (CNOT7) and Caf1b (CNOT8) deadenylase subunits of the Ccr4-not complex.
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| Doidge R, Mittal S, Aslam A, Winkler GS.
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| PLoS One. ;7(12):e51331. doi: 10.1371/journal.pone.0051331. Epub 2012 Dec 7 2012
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6 | BTG1, BTG2, BTG3, BTG4, CNOT7, CNOT8, TOB1, TOB2
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| The mammalian anti-proliferative BTG/Tob protein family.
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| Winkler GS.
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| J Cell Physiol 222(1):66-72. Review.PMID: 19746446 2010
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7 | BTG2, BTG3, BTG4
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| Frequent promoter hypermethylation and transcriptional downregulation of BTG4 gene in gastric cancer.
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| Dong W, Tu S, Xie J, Sun P, Wu Y, Wang L.
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| Biochem Biophys Res Commun 387(1):132-8. Epub 2009 Jul 1.PMID: 19576178 2009
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8 | POU2AF1, BTG4
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| Identification of a potential role for POU2AF1 and BTG4 in the deletion of 11q23 in chronic lymphocytic leukemia.
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| Auer RL, Starczynski J, McElwaine S, Bertoni F, Newland AC, Fegan CD, Cotter FE.
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| Genes Chromosomes Cancer 43(1):1-10. 2005
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9 | BTG1, BTG2, BTG3, BTG4, TOB1, TOB2
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| Antiproliferative proteins of the BTG/Tob family are degraded by the ubiquitin-proteasome system.
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| Sasajima H, Nakagawa K, Yokosawa H.
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| Eur J Biochem 269(14):3596-604.PMID: 12135500 2002
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10 | BTG4, CNOT7, BTG3, TOB1, TOB2
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| Association of ANA, a member of the antiproliferative Tob family proteins, with a Caf1 component of the CCR4 transcriptional regulatory complex.
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| Yoshida Y, Hosoda E, Nakamura T, Yamamoto T.
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| Jpn J Cancer Res 92(6):592-6. 2001
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11 | BTG4
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| Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium.
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| Buanne P, Corrente G, Micheli L, Palena A, Lavia P, Spadafora C, Lakshmana MK, Rinaldi A, Banfi S, Quarto M, Bulfone A, Tirone F.
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| Genomics 68(3):253-63. 2000
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