Citations for
1BSG
CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury.
Yee C, Main NM, Terry A, Stevanovski I, Maczurek A, Morgan AJ, Calabro S, Potter AJ, Iemma TL, Bowen DG, Ahlenstiel G, Warner FJ, McCaughan GW, McLennan SV, Shackel NA.
PLoS One 14(7):e0215557. doi: 10.1371/journal.pone.0215557. eCollection 2019. 2019
2BSG
Hypo-phosphorylated CD147 promotes migration and invasion of hepatocellular carcinoma cells and predicts a poor prognosis.
Jin J, Wang SJ, Cui J, Li L, Li JY, Liu FL, Sun XX, Jiang JL, Cui HY, Chen ZN.
Cell Oncol (Dordr) 42(4):537-554. doi: 10.1007/s13402-019-00444-0. Epub 2019 Apr 23. 2019
3BSG
CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling.
Yoshioka T, Kosugi T, Masuda T, Watanabe T, Ryuge A, Nagaya H, Maeda K, Sato Y, Katsuno T, Kato N, Ishimoto T, Yuzawa Y, Maruyama S, Kadomatsu K.
Am J Pathol 189(7):1338-1350. doi: 10.1016/j.ajpath.2019.04.003. Epub 2019 Apr 20. 2019
4BSG
CD147 as an apoptosis regulator in spermatogenesis: deciphering its association with matrix metalloproteinases' pathway.
Asgari R, Mansouri K, Bakhtiari M, Vaisi-Raygani A.
Mol Biol Rep 46(1):1099-1105. doi: 10.1007/s11033-018-4568-y. Epub 2019 Jan 2. 2019
5BSG, YIPF2
YIPF2 is a novel Rab-GDF that enhances HCC malignant phenotypes by facilitating CD147 endocytic recycle.
Qi S, Su L, Li J, Zhao P, Zhang Q, Niu X, Liu J, Jia G, Wei X, Tavernier J, Jiang J, Chen Z, Zhang S.
Cell Death Dis. Jun 12;10(6):462. doi: 10.1038/s41419-019-1709-8 2019
6BSG, PPIA
Cyclophilin A and CD147 associate with progression of diabetic nephropathy.
Chiu PF, Su SL, Tsai CC, Wu CL, Kuo CL, Kor CT, Chang CC, Liu CS.
Free Radic Res 52(11-12):1456-1463. doi: 10.1080/10715762.2018.1523545. Epub 2018 Dec 20. 2018
7BSG, IGFBP2
Downregulation of CD147 induces malignant melanoma cell apoptosis via the regulation of IGFBP2 expression.
Zhao S, Wu L, Kuang Y, Su J, Luo Z, Wang Y, Li J, Zhang J, Chen W, Li F, He Y, Tao J, Zhou J, Xu X, Peng C, Chen X.
Int J Oncol 53(6):2397-2408. doi: 10.3892/ijo.2018.4579. Epub 2018 Oct 1. 2018
8BSG
CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.
Vanarsdall AL, Pritchard SR, Wisner TW, Liu J, Jardetzky TS, Johnson DC.
mBio 9(3). pii: e00781-18. doi: 10.1128/mBio.00781-18. 2018
9BSG, CXCL1
CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.
Shi WP, Ju D, Li H, Yuan L, Cui J, Luo D, Chen ZN, Bian H.
Int J Mol Sci 19(4). pii: E1145. doi: 10.3390/ijms19041145. 2018
10BSG, SLC16A4, TMPRSS11B
Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism.
Updegraff BL, Zhou X, Guo Y, Padanad MS, Chen PH, Yang C, Sudderth J, Rodriguez-Tirado C, Girard L, Minna JD, Mishra P, DeBerardinis RJ, O'Donnell KA.
Cell Rep 25(8):2223-2233.e6. doi: 10.1016/j.celrep.2018.10.100. 2018
11ATP2B1, BSG, NPTN
Structure of the human plasma membrane Ca2+-ATPase 1 in complex with its obligatory subunit neuroplastin
Gong D, Chi X, Ren K, Huang G, Zhou G, Yan N, Lei J, Zhou Q.
Nat Commun. Sep 6;9(1):3623. doi: 10.1038/s41467-018-06075-7. 2018
12BSG, RING1
Nuclear envelope-distributed CD147 interacts with and inhibits the transcriptional function of RING1 and promotes melanoma cell motility.
Chen J, Peng C, Lei L, Zhang J, Zeng W, Chen X.
PLoS One 12(8):e0183689. doi: 10.1371/journal.pone.0183689. eCollection 2017. 2017
13BSG, PPIA
Potential role of cyclophilin A in regulating cytokine secretion.
Dawar FU, Xiong Y, Khattak MNK, Li J, Lin L, Mei J.
J Leukoc Biol 102(4):989-992. doi: 10.1189/jlb.3RU0317-090RR. Epub 2017 Jul 20. Review. 2017
14BSG
Overexpression of EMMPRIN is associated with lymph node metastasis and advanced stage of non-small cell lung cancer: a retrospective study.
Liu B, Wan Z, Sheng B, Lin Y, Fu T, Zeng Q, Qi C.
BMC Pulm Med 17(1):214. doi: 10.1186/s12890-017-0540-1. 2017
15ATP2B1, BSG, NPTN
Neuroplastin and Basigin Are Essential Auxiliary Subunits of Plasma Membrane Ca2+-ATPases and Key Regulators of Ca2+ Clearance.
Schmidt N, Kollewe A, Constantin CE, Henrich S, Ritzau-Jost A, Bildl W, Saalbach A, Hallermann S, Kulik A, Fakler B, Schulte U.
Neuron 96(4):827-838.e9. doi: 10.1016/j.neuron.2017.09.038. Epub 2017 Oct 19. 2017
16BSG, SMAD4
CD147-induced cell proliferation is associated with Smad4 signal inhibition.
Qin H, Rasul A, Li X, Masood M, Yang G, Wang N, Wei W, He X, Watanabe N, Li J, Li X.
Exp Cell Res 358(2):279-289. doi: 10.1016/j.yexcr.2017.07.003. Epub 2017 Jul 3. 2017
17BSG
Up-regulated basigin-2 in microglia induced by hypoxia promotes retinal angiogenesis.
Yin J, Xu WQ, Ye MX, Zhang Y, Wang HY, Zhang J, Li Y, Wang YS.
J Cell Mol Med 21(12):3467-3480. doi: 10.1111/jcmm.13256. Epub 2017 Jun 29. 2017
18BSG
CD147 regulates extrinsic apoptosis in spermatocytes by modulating NFκB signaling pathways.
Wang C, Fok KL, Cai Z, Chen H, Chan HC.
Oncotarget 8(2):3132-3143. doi: 10.18632/oncotarget.13624. 2017
19BSG
Extracellular matrix metalloproteinase inducer (EMMPRIN) is a potential biomarker of angiogenesis in proliferative diabetic retinopathy.
Abu El-Asrar AM, Ahmad A, Alam K, Siddiquei MM, Mohammad G, Hertogh G, Mousa A, Opdenakker G.
Acta Ophthalmol 95(7):697-704. doi: 10.1111/aos.13284. Epub 2016 Nov 18. 2017
20BSG, PPIA
CD147 stimulates hepatoma cells escaping from immune surveillance of T cells by interaction with Cyclophilin A.
Ren YX, Wang SJ, Fan JH, Sun SJ, Li X, Padhiar AA, Zhang JN.
Biomed Pharmacother 80:289-297. doi: 10.1016/j.biopha.2016.03.036. Epub 2016 Apr 1. 2016
21BSG
CD147/EMMPRIN overexpression and prognosis in cancer: A systematic review and meta-analysis.
Xin X, Zeng X, Gu H, Li M, Tan H, Jin Z, Hua T, Shi R, Wang H.
Sci Rep 6:32804. doi: 10.1038/srep32804. Review. 2016
22BSG
Spatiotemporal expression of caveolin-1 and EMMPRIN during mouse tooth development.
Shi L, Li L, Wang D, Li S, Chen Z, An Z.
J Mol Histol 47(3):337-44. doi: 10.1007/s10735-016-9675-2. Epub 2016 Apr 13. 2016
23BSG, NFATC1
CD147 promotes the formation of functional osteoclasts through NFATc1 signalling.
Nishioku T, Terasawa M, Baba M, Yamauchi A, Kataoka Y.
Biochem Biophys Res Commun 473(2):620-4. doi: 10.1016/j.bbrc.2016.03.147. Epub 2016 Mar 31. 2016
24BSG, TRAF6
TRAF6 regulates melanoma invasion and metastasis through ubiquitination of Basigin.
Luo Z, Zhang X, Zeng W, Su J, Yang K, Lu L, Lim CB, Tang W, Wu L, Zhao S, Jia X, Peng C, Chen X.
Oncotarget 7(6):7179-92. doi: 10.18632/oncotarget.6886. 2016
25BSG
Basigin (CD147), a multifunctional transmembrane glycoprotein with various binding partners.
Muramatsu T.
J Biochem 159(5):481-90. doi: 10.1093/jb/mvv127. Epub 2015 Dec 18. Review. 2016
26BSG
Activation of TGF-β1-CD147 positive feedback loop in hepatic stellate cells promotes liver fibrosis.
Li HY, Ju D, Zhang DW, Li H, Kong LM, Guo Y, Li C, Wang XL, Chen ZN, Bian H.
Sci Rep 5:16552. doi: 10.1038/srep16552. 2015
27BSG
CD147 promotes liver fibrosis progression via VEGF-A/VEGFR2 signalling-mediated cross-talk between hepatocytes and sinusoidal endothelial cells.
Yan Z, Qu K, Zhang J, Huang Q, Qu P, Xu X, Yuan P, Huang X, Shao Y, Liu C, Zhang H, Xing J.
Clin Sci (Lond) 129(8):699-710. doi: 10.1042/CS20140823. Epub 2015 Jun 16. 2015
28BSG
The role of EMMPRIN in T cell biology and immunological diseases.
Hahn JN, Kaushik DK, Yong VW.
J Leukoc Biol 98(1):33-48. doi: 10.1189/jlb.3RU0215-045R. Epub 2015 May 14. Review. 2015
29BSG, KDR
EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.
Khayati F, Pérez-Cano L, Maouche K, Sadoux A, Boutalbi Z, Podgorniak MP, Maskos U, Setterblad N, Janin A, Calvo F, Lebbé C, Menashi S, Fernandez-Recio J, Mourah S.
Oncotarget 6(12):9766-80. 2015
30BSG, SLC3A2
CD147-CD98hc complex contributes to poor prognosis of non-small cell lung cancer patients through promoting cell proliferation via the PI3K/Akt signaling pathway.
Fei F, Li X, Xu L, Li D, Zhang Z, Guo X, Yang H, Chen Z, Xing J.
Ann Surg Oncol 21(13):4359-68. doi: 10.1245/s10434-014-3816-1. Epub 2014 Aug 2. 2014
31ADAM12, BSG
EMMPRIN and ADAM12 in prostate cancer: preliminary results of a prospective study.
Bilgin Doğru E, Dizdar Y, Akşit E, Ural F, Şanlı Ö, Yasasever V.
Tumour Biol 35(11):11647-53. doi: 10.1007/s13277-014-2514-8. 2014
32BSG, GP6
Circulating levels of soluble EMMPRIN (CD147) correlate with levels of soluble glycoprotein VI in human plasma.
Pennings GJ, Yong AS, Wong C, Al-Tamimi M, Gardiner EE, Andrews RK, Kritharides L.
Platelets 25(8):639-42. doi: 10.3109/09537104.2013.852660. Epub 2013 Nov 18. 2014
33BSG, SLC16A1, SLC16A4
CD147 required for corneal endothelial lactate transport.
Li S, Nguyen TT, Bonanno JA.
Invest Ophthalmol Vis Sci 55(7):4673-81. doi: 10.1167/iovs.14-14386. 2014
34BSG
Important functional roles of basigin in thymocyte development and T cell activation.
Yao H, Teng Y, Sun Q, Xu J, Chen YT, Hou N, Cheng X, Yang X, Chen ZN.
Int J Biol Sci 10(1):43-52. doi: 10.7150/ijbs.6818. eCollection 2013. 2013
35BSG, GPER1
Stimulation of GPR30 increases release of EMMPRIN-containing microvesicles in human uterine epithelial cells.
Burnett LA, Light MM, Mehrotra P, Nowak RA.
J Clin Endocrinol Metab 97(12):4613-22. doi: 10.1210/jc.2012-2098. Epub 2012 Sep 25. Erratum in: J Clin Endocrinol Metab. 2013 Nov;98(11):4546. 2012
36BSG
EMMPRIN: a novel regulator of leukocyte transmigration into the CNS in multiple sclerosis and experimental autoimmune encephalomyelitis.
Agrawal SM, Silva C, Tourtellotte WW, Yong VW.
J Neurosci 31(2):669-77. 2011
37BSG
Characterization of basigin isoforms and the inhibitory function of basigin-3 in human hepatocellular carcinoma proliferation and invasion.
Liao CG, Kong LM, Song F, Xing JL, Wang LX, Sun ZJ, Tang H, Yao H, Zhang Y, Wang L, Wang Y, Yang XM, Li Y, Chen ZN.
Mol Cell Biol 31(13):2591-604. Epub 2011 May 2. 2011
38BSG
HAb18G/CD147 promotes epithelial-mesenchymal transition through TGF-β signaling and is transcriptionally regulated by Slug.
Wu J, Ru NY, Zhang Y, Li Y, Wei D, Ren Z, Huang XF, Chen ZN, Bian H.
Oncogene 30(43):4410-27. doi: 10.1038/onc.2011.149. Epub 2011 May 2. 2011
39BSG, SLC16A1, SLC16A4
CD147 subunit of lactate/H+ symporters MCT1 and hypoxia-inducible MCT4 is critical for energetics and growth of glycolytic tumors.
Le Floch R, Chiche J, Marchiq I, Naiken T, Ilc K, Murray CM, Critchlow SE, Roux D, Simon MP, Pouysségur J.
Proc Natl Acad Sci U S A 108(40):16663-8. doi: 10.1073/pnas.1106123108. Epub 2011 Sep 19. Erratum in: Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):20166. 2011
40BSG, SLC16A4
Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer.
Pértega-Gomes N, Vizcaíno JR, Miranda-Gonçalves V, Pinheiro C, Silva J, Pereira H, Monteiro P, Henrique RM, Reis RM, Lopes C, Baltazar F.
BMC Cancer 11:312. doi: 10.1186/1471-2407-11-312. 2011
41BSG
EMMPRIN regulates the canonical Wnt/beta-catenin signaling pathway, a potential role in accelerating lung tumorigenesis.
Sidhu SS, Nawroth R, Retz M, Lemjabbar-Alaoui H, Dasari V, Basbaum C.
Oncogene 29(29):4145-56. Epub 2010 May 31. 2010
42BSG
Extracellular matrix metalloproteinase inducer (EMMPRIN) is increased in human left ventricle after acute myocardial infarction.
Nie R, Xie S, Du B, Liu X, Deng B, Wang J.
Arch Med Res 40(7):605-11.PMID: 20082877 2009
43BSG
Structure of the EMMPRIN N-terminal domain 1: dimerization via beta-strand swapping.
Luo J, Teplyakov A, Obmolova G, Malia T, Wu SJ, Beil E, Baker A, Swencki-Underwood B, Zhao Y, Sprenkle J, Dixon K, Sweet R, Gilliland GL.
Proteins 77(4):1009-14. No abstract available. PMID: 19768682 2009
44BSG, GP6
EMMPRIN (CD147) is a novel receptor for platelet GPVI and mediates platelet rolling via GPVI-EMMPRIN interaction.
Seizer P, Borst O, Langer HF, Bültmann A, Münch G, Herouy Y, Stellos K, Krämer B, Bigalke B, Büchele B, Bachem MG, Vestweber D, Simmet T, Gawaz M, May AE.
Thromb Haemost 101(4):682-6.PMID: 19350111 2009
45BSG
CD147 impacts angiogenesis and metastasis formation.
Voigt H, Vetter-Kauczok CS, Schrama D, Hofmann UB, Becker JC, Houben R.
Cancer Invest 27(3):329-33.PMID: 19160100 2009
46BSG
CD147 inhibits the nuclear factor of activated T-cells by impairing Vav1 and Rac1 downstream signaling.
Ruiz S, Castro-Castro A, Bustelo XR.
J Biol Chem 283(9):5554-66. Epub 2007 Dec 26. 2008
47BSG
Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted Abeta.
Vetrivel KS, Zhang X, Meckler X, Cheng H, Lee S, Gong P, Lopes KO, Chen Y, Iwata N, Yin KJ, Lee JM, Parent AT, Saido TC, Li YM, Sisodia SS, Thinakaran G.
J Biol Chem 283(28):19489-98. Epub 2008 May 1. 2008
48BSG
EMMPRIN mediates beta-adrenergic receptor-stimulated matrix metalloproteinase activity in cardiac myocytes.
Siwik DA, Kuster GM, Brahmbhatt JV, Zaidi Z, Malik J, Ooi H, Ghorayeb G.
J Mol Cell Cardiol 44(1):210-7. Epub 2007 Jul 31.PMID: 17869266 2008
49BSG
CD147 regulates vascular endothelial growth factor-A expression, tumorigenicity, and chemosensitivity to curcumin in hepatocellular carcinoma.
Jia L, Wang H, Qu S, Miao X, Zhang J.
IUBMB Life 60(1):57-63.PMID: 18379992 2008
50BSG, ITGB2, SPN
LFA-1-mediated leukocyte adhesion regulated by interaction of CD43 with LFA-1 and CD147.
Khunkaewla P, Schiller HB, Paster W, Leksa V, Cermák L, Andera L, Horejsí V, Stockinger H.
Mol Immunol 45(6):1703-11. Epub 2007 Nov 9. 2008
51BSG, MMP14
Membrane type 1 matrix metalloproteinase (MT1-MMP/MMP-14) cleaves and releases a 22-kDa extracellular matrix metalloproteinase inducer (EMMPRIN) fragment from tumor cells.
Egawa N, Koshikawa N, Tomari T, Nabeshima K, Isobe T, Seiki M.
J Biol Chem 281(49):37576-85. Epub 2006 Oct 18. 2006
52BSG
Upregulated EMMPRIN/CD147 might contribute to growth and angiogenesis of gastric carcinoma: a good marker for local invasion and prognosis.
Zheng HC, Takahashi H, Murai Y, Cui ZG, Nomoto K, Miwa S, Tsuneyama K, Takano Y.
Br J Cancer 95(10):1371-8. Epub 2006 Oct 31. 2006
53BSG, OK
The glycosylation characteristic of hepatoma-associated antigen HAb18G/CD147 in human hepatoma cells.
Yu XL, Jiang JL, Li L, Feng Q, Xu J, Chen ZN.
Int J Biochem Cell Biol 38(11):1939-45. Epub 2006 May 27. 2006
54BSG
High incidence of EMMPRIN expression in human tumors.
Riethdorf S, Reimers N, Assmann V, Kornfeld JW, Terracciano L, Sauter G, Pantel K.
Int J Cancer 119(8):1800-10. 2006
55BSG
EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair.
Gabison EE, Hoang-Xuan T, Mauviel A, Menashi S.
Biochimie 87(3-4):361-8. Review. 2005
56BSG, EMB, SLC16A7, SLC16A8
Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70).
Wilson MC, Meredith D, Fox JE, Manoharan C, Davies AJ, Halestrap AP.
J Biol Chem 280(29):27213-21. Epub 2005 May 24. 2005
57BSG
Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts.
Kanekura T, Chen X, Kanzaki T.
Int J Cancer 99(4):520-8. 2002
58BSG
Extracellular matrix metalloproteinase inducer (EMMPRIN) is induced upon monocyte differentiation and is expressed in human atheroma.
Major TC, Liang L, Lu X, Rosebury W, Bocan TM.
Arterioscler Thromb Vasc Biol 22(7):1200-7. 2002
59BSG, PPIA, PPIB
CD147 is a signaling receptor for cyclophilin B.
Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M.
Biochem Biophys Res Commun 288(4):786-8. 2001
60BSG
Expression of emmprin by oral squamous cell carcinoma.
Bordador LC, Li X, Toole B, Chen B, Regezi J, Zardi L, Hu Y, Ramos DM.
Int J Cancer 85(3):347-52. 2000
61BSG
EMMPRIN (CD147), an inducer of matrix metalloproteinase synthesis, also binds interstitial collagenase to the tumor cell surface.
Guo H, Li R, Zucker S, Toole BP.
Cancer Res 60(4):888-91. 2000
62BSG
Expression of emmprin (CD147), a cell surface inducer of matrix metalloproteinases, in normal human brain and gliomas.
Sameshima T, Nabeshima K, Toole BP, Yokogami K, Okada Y, Goya T, Koono M, Wakisaka S.
Int J Cancer 88(1):21-7. 2000
63BSG
Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.
Guo H, Majmudar G, Jensen TC, Biswas C, Toole BP, Gordon MK.
Gene 220(1-2):99-108. 1998
64BSG
The pattern of expression of CD147/neurothelin during human T-cell ontogeny as defined by the monoclonal antibody 8D6.
Kirsch AH, et al.
Tissue Antigens 50 : 147-152. 1997
65BSG
Human keratinocytes express EMMPRIN, an extracellular matrix metalloproteinase inducer.
DeCastro R, Zhang Y, Guo H, Kataoka H, Gordon MK, Toole Bp, Biswas G.
J Invest Dermatol 106(6):1260-5. 1996
66BSG
Mapping basigin (BSG), a member of the immunoglobulin superfamily, to 19p13.3.
Kaname T, et al.
Cytogenet Cell Genet 64 : 195-197. 1993