Citations for
1BRCA2, BRIP1, FANCD2
FANCD2, FANCJ and BRCA2 cooperate to promote replication fork recovery independently of the Fanconi Anemia core complex.
Raghunandan M, Chaudhury I, Kelich SL, Hanenberg H, Sobeck A.
Cell Cycle 14(3):342-53. doi: 10.4161/15384101.2014.987614. 2015
2BRIP1, MSH5
hMSH5 Facilitates the Repair of Camptothecin-induced Double-strand Breaks through an Interaction with FANCJ.
Xu Y, Wu X, Her C.
J Biol Chem. Jul 24;290(30):18545-58. doi: 10.1074/jbc.M115.642884. Epub 2015 Jun 8 2015
3BRIP1, FANCD2
The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.
Chen X, Wilson JB, McChesney P, Williams SA, Kwon Y, Longerich S, Marriott AS, Sung P, Jones NJ, Kupfer GM.
J Biol Chem 289(37):25774-82. doi: 10.1074/jbc.M114.552570. Epub 2014 Jul 28. 2014
4BRIP1, FANCD2
The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.
Chen X, Wilson JB, McChesney P, Williams SA, Kwon Y, Longerich S, Marriott AS, Sung P, Jones NJ, Kupfer GM.
J Biol Chem 289(37):25774-82. doi: 10.1074/jbc.M114.552570. Epub 2014 Jul 28. 2014
5BRIP1, RPA1, TERF2
Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.
Sommers JA, Banerjee T, Hinds T, Wan B, Wold MS, Lei M, Brosh RM Jr.
J Biol Chem 289(29):19928-41. doi: 10.1074/jbc.M113.542456. Epub 2014 Jun 3. 2014
6BRCA1, BRIP1, PLK1
BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1.
Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D.
Cell Cycle 13(23):3685-97. doi: 10.4161/15384101.2014.964973. 2014
7BRIP1
FANCJ/BACH1 acetylation at lysine 1249 regulates the DNA damage response.
Xie J, Peng M, Guillemette S, Quan S, Maniatis S, Wu Y, Venkatesh A, Shaffer SA, Brosh RM Jr, Cantor SB.
PLoS Genet 8(7):e1002786. doi: 10.1371/journal.pgen.1002786. Epub 2012 Jul 5. 2012
8BRIP1
The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function.
Wu Y, Sommers JA, Loiland JA, Kitao H, Kuper J, Kisker C, Brosh RM Jr.
J Biol Chem 287(26):21699-716. doi: 10.1074/jbc.M112.351338. Epub 2012 May 10. 2012
9BRIP1
BRCA1-mediated repression of mutagenic end-joining of DNA double-strand breaks requires complex formation with BACH1.
Dohrn L, Salles D, Siehler SY, Kaufmann J, Wiesmüller L.
Biochem J 441(3):919-26. doi: 10.1042/BJ20110314. 2012
10BRIP1, TOPBP1
Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.
Leung CC, Gong Z, Chen J, Glover JN.
J Biol Chem 286(6):4292-301. Epub 2010 Dec 2. 2011
11BLM, BRIP1
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.
Suhasini AN, Rawtani NA, Wu Y, Sommers JA, Sharma S, Mosedale G, North PS, Cantor SB, Hickson ID, Brosh RM Jr.
EMBO J 30(4):692-705. Epub 2011 Jan 14. 2011
12BRIP1
Mutations in BRIP1 confer high risk of ovarian cancer.
Rafnar T, Gudbjartsson DF, Sulem P, Jonasdottir A, Sigurdsson A, Jonasdottir A, Besenbacher S, Lundin P, Stacey SN, Gudmundsson J, Magnusson OT, le Roux L, Orlygsdottir G, Helgadottir HT, Johannsdottir H, Gylfason A, Tryggvadottir L, Jonasson JG, de Juan A, Ortega E, Ramon-Cajal JM, García-Prats MD, Mayordomo C, Panadero A, Rivera F, Aben KK, van Altena AM, Massuger LF, Aavikko M, Kujala PM, Staff S, Aaltonen LA, Olafsdottir K, Bjornsson J, Kong A, Salvarsdottir A, Saemundsson H, Olafsson K, Benediktsdottir KR, Gulcher J, Masson G, Kiemeney LA, Mayordomo JI, Thorsteinsdottir U, Stefansson K.
Nat Genet 43(11):1104-7. doi: 10.1038/ng.955. 2011
13BARD1, BRCA1, BRCA2, BRIP1, CHEK2, MRE11A, MSH6, NBN, PALB2, RAD50, RAD51c, TP53
Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM, Roeb W, Agnew KJ, Stray SM, Wickramanayake A, Norquist B, Pennington KP, Garcia RL, King MC, Swisher EM.
Proc Natl Acad Sci U S A 108(44):18032-7. doi: 10.1073/pnas.1115052108. Epub 2011 Oct 17. 2011
14BRIP1, HRAS, KRAS
Oncogenic RAS regulates BRIP1 expression to induce dissociation of BRCA1 from chromatin, inhibit DNA repair, and promote senescence.
Tu Z, Aird KM, Bitler BG, Nicodemus JP, Beeharry N, Xia B, Yen TJ, Zhang R.
Dev Cell 21(6):1077-91. doi: 10.1016/j.devcel.2011.10.010. Epub 2011 Dec 1. 2011
15BRIP1, TOPBP1
BACH1/FANCJ acts with TopBP1 and participates early in DNA replication checkpoint control.
Gong Z, Kim JE, Leung CC, Glover JN, Chen J.
Mol Cell 37(3):438-46.PMID: 20159562 2010
16BRCA1, BRIP1
Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass.
Xie J, Litman R, Wang S, Peng M, Guillemette S, Rooney T, Cantor SB.
Oncogene 29(17):2499-508. Epub 2010 Feb 22. 2010
17BRIP1, FANCD2
FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses.
Zhang F, Fan Q, Ren K, Auerbach AD, Andreassen PR.
Chromosoma 119(6):637-49. doi: 10.1007/s00412-010-0285-6. Epub 2010 Jul 31. 2010
18BRIP1
FANCJ uses its motor ATPase to destabilize protein-DNA complexes, unwind triplexes, and inhibit RAD51 strand exchange.
Sommers JA, Rawtani N, Gupta R, Bugreev DV, Mazin AV, Cantor SB, Brosh RM Jr.
J Biol Chem 284(12):7505-17. Epub 2009 Jan 16. 2009
19BRIP1, RPA1
FANCJ Helicase Uniquely Senses Oxidative Base Damage in Either Strand of Duplex DNA and Is Stimulated by Replication Protein A to Unwind the Damaged DNA Substrate in a Strand-specific Manner.
Suhasini AN, Sommers JA, Mason AC, Voloshin ON, Camerini-Otero RD, Wold MS, Brosh RM Jr.
J Biol Chem 284(27):18458-70. Epub 2009 May 5. 2009
20BRIP1, FANCM, PALB2
Remodeling of DNA replication structures by the branch point translocase FANCM.
Gari K, Décaillet C, Delannoy M, Wu L, Constantinou A.
Proc Natl Acad Sci U S A 105(42):16107-12. Epub 2008 Oct 8. 2008
21BRIP1, FANCJ
FANCJ is a structure-specific DNA helicase associated with the maintenance of genomic G/C tracts.
London TB, Barber LJ, Mosedale G, Kelly GP, Balasubramanian S, Hickson ID, Boulton SJ, Hiom K.
J Biol Chem 283(52):36132-9. Epub 2008 Oct 31. 2008
22BRIP1
Mutational analysis of the breast cancer susceptibility gene BRIP1 /BACH1/FANCJ in high-risk non-BRCA1/BRCA2 breast cancer families.
Guénard F, Labrie Y, Ouellette G, Joly Beauparlant C, Simard J, Durocher F; INHERIT BRCAs.
J Hum Genet 53(7):579-91. Epub 2008 Apr 15. 2008
23BRIP1, FANCJ
FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability.
Wu Y, Shin-ya K, Brosh RM Jr.
Mol Cell Biol 28(12):4116-28. Epub 2008 Apr 21.PMID: 18426915 2008
24BRIP1, RPA1
FANCJ (BACH1) helicase forms DNA damage inducible foci with replication protein A and interacts physically and functionally with the single-stranded DNA-binding protein.
Gupta R, Sharma S, Sommers JA, Kenny MK, Cantor SB, Brosh RM Jr.
Blood 110(7):2390-8. Epub 2007 Jun 27.PMID: 17596542 2007
25BRIP1, FANCJ
Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.
Seal S, Thompson D, Renwick A, Elliott A, Kelly P, Barfoot R, Chagtai T, Jayatilake H, Ahmed M, Spanova K, North B, McGuffog L, Evans DG, Eccles D; Breast Cancer Susceptibility Collaboration (UK); Easton DF, Stratton MR, Rahman N.
Nat Genet 38(11):1239-41. Epub 2006 Oct 8. 2006
26BRIP1, FANCJ
The BRCA1-interacting helicase BRIP1 is deficient in Fanconi anemia.
Levran O, Attwooll C, Henry RT, Milton KL, Neveling K, Rio P, Batish SD, Kalb R, Velleuer E, Barral S, Ott J, Petrini J, Schindler D, Hanenberg H, Auerbach AD.
Nat Genet 37(9):931-3. Epub 2005 Aug 21. 2005
27FANCJ, BRIP1
The DNA helicase BRIP1 is defective in Fanconi anemia complementation group J.
Levitus M, Waisfisz Q, Godthelp BC, de Vries Y, Hussain S, Wiegant WW, Elghalbzouri-Maghrani E, Steltenpool J, Rooimans MA, Pals G, Arwert F, Mathew CG, Zdzienicka MZ, Hiom K, De Winter JP, Joenje H.
Nat Genet 37(9):934-5. Epub 2005 Aug 21. 2005
28BRIP1, FANCJ
The BRIP1 helicase functions independently of BRCA1 in the Fanconi anemia pathway for DNA crosslink repair.
Bridge WL, Vandenberg CJ, Franklin RJ, Hiom K.
Nat Genet 37(9):953-7. Epub 2005 Aug 21. 2005
29BRIP1,FANCJ
BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.
Litman R, Peng M, Jin Z, Zhang F, Zhang J, Powell S, Andreassen PR, Cantor SB.
Cancer Cell 8(3):255-65. 2005
30BACH1, BRCA1, BRIP1
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.
Cell 105(1):149-60. 2001
31BRIP1
SUVi and BACH1: a new subfamily of mammalian helicases?
Menichini P, Linial M.
Mutat Res 487(1-2):67-71. 2001
32BRCA1, BRIP1
Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas.
Yoshikawa K, Ogawa T, Baer R, Hemmi H, Honda K, Yamauchi A, Inamoto T, Ko K, Yazumi S, Motoda H, Kodama H, Noguchi S, Gazdar AF, Yamaoka Y, Takahashi R.
Int J Cancer 88(1):28-36. 2000