Citations for
1BRD7, INSR
BRD7 improves glucose homeostasis independent of IRS proteins.
Kim Y, Lee JM, Han Y, Tao R, White MF, Liu R, Park SW.
J Endocrinol. Aug 14;258(3):e230119. doi: 10.1530/JOE-23-0119. 2023
2BIRC2, BRD7
BRD7 inhibits enhancer activity and expression of BIRC2 to suppress tumor growth and metastasis in nasopharyngeal carcinoma.
Li M, Wei Y, Liu Y, Wei J, Zhou X, Duan Y, Chen S, Xue C, Zhan Y, Zheng L, Deng H, Tang F, Fan S, Xiong W, Li G, Tan M, Zhou M.
Cell Death Dis. Feb 14;14(2):121. doi: 10.1038/s41419-023-05632-3. 2023
3BRD7, GSK3B, NFE2L2
Upregulation of BRD7 protects podocytes against high glucose-induced apoptosis by enhancing Nrf2 in a GSK-3β-dependent manner.
Yu X, Jiang N, Li J, Li X, He S.
Tissue Cell. Jun;76:101813. doi: 10.1016/j.tice.2022.101813. Epub 2022 2022
4BRD7
Emerging Roles of BRD7 in Pathophysiology.
Park SW, Lee JM.
Int J Mol Sci. Sep 27;21(19):7127. doi: 10.3390/ijms21197127. 2020
5BRD7
Expression and subcellular localization of the bromodomain-containing protein 7 is a prognostic biomarker in breast cancer.2020 PMID:
Vivenza D, Garrone O, Brizio R, Mantovani F, Del Sal G, Merlano M, Crook T, Lo Nigro C.
Anticancer Drugs. Apr;31(4):423-430. doi: 10.1097/CAD.0000000000000897. 2020
6BRD7, OLIG2, SEH1L
Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination
Liu Z, Yan M, Liang Y, Liu M, Zhang K, Shao D, Jiang R, Li L, Wang C, Nussenzveig DR, Zhang K, Chen S, Zhong C, Mo W, Fontoura BMA, Zhang L.
Neuron May 8;102(3):587-601.e7. doi: 10.1016/j.neuron.2019.02.018. Epub 2019 Mar 12. 2019
7BRD7
BRD7 deficiency leads to the development of obesity and hyperglycemia.
Lee JM, Kim Y, Salazar Hernández MA, Han Y, Liu R, Park SW.
Sci Rep. Mar 29;9(1):5327. doi: 10.1038/s41598-019-41713-0. 2019
8BRD7
BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.
Zhao R, Liu Y, Wang H, Yang J, Niu W, Fan S, Xiong W, Ma J, Li X, Phillips JB, Tan M, Qiu Y, Li G, Zhou M.
Cell Mol Immunol. Oct;14(10):830-841. doi: 10.1038/cmi.2016.31. Epub 2016 Jul 4. 2017
9BRD7
The role of BRD7 in embryo development and glucose metabolism.
Kim Y, Andrés Salazar Hernández M, Herrema H, Delibasi T, Park SW.
J Cell Mol Med. Aug;20(8):1561-70. doi: 10.1111/jcmm.12907. Erratum in: J Cell Mol Med. 2017 Jun;21(6):1243. 2016
10BRD7, XAF1
XIAP-associating factor 1, a transcriptional target of BRD7, contributes to endothelial cell senescence. 2016 PMID:
Heo JI, Kim W, Choi KJ, Bae S, Jeong JH, Kim KS.
Oncotarget Feb 2;7(5):5118-30. doi: 10.18632/oncotarget.6962. 2016
11BRD7
Bromodomain-containing protein 7 (BRD7) as a potential tumor suppressor in hepatocellular carcinoma.
Chen CL, Wang Y, Pan QZ, Tang Y, Wang QJ, Pan K, Huang LX, He J, Zhao JJ, Jiang SS, Zhang XF, Zhang HX, Zhou ZQ, Weng de S, Xia JC.
Oncotarget. Mar 29;7(13):16248-61. doi: 10.18632/oncotarget.7637. 2016
12BRD7
Inactivation of BRD7 results in impaired cognitive behavior and reduced synaptic plasticity of the medial prefrontal cortex.
Xu Y, Cao W, Zhou M, Li C, Luo Y, Wang H, Zhao R, Jiang S, Yang J, Liu Y, Wang X, Li X, Xiong W, Ma J, Peng S, Zeng Z, Li X, Tan M, Li G.
Behav Brain Res. Jun 1;286:1-10. doi: 10.1016/j.bbr.2015.02.031. Epub 2015 Feb 23. 2015
13BRD7, XBP1
BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3K
Park SW, Herrema H, Salazar M, Cakir I, Cabi S, Basibuyuk Sahin F, Chiu YH, Cantley LC, Ozcan U
Cell Metab. Jul 1;20(1):73-84. doi: 10.1016/j.cmet.2014.04.006. Epub 2014 May 15. Erratum in: Cell Metab. 2014 Dec 2;20(6):1088. 2014
14BRD7, PRMT5
Bromodomain protein 7 interacts with PRMT5 and PRC2, and is involved in transcriptional repression of their target genes.
Tae S, Karkhanis V, Velasco K, Yaneva M, Erdjument-Bromage H, Tempst P, Sif S.
Nucleic Acids Res 39(13):5424-38. Epub 2011 Mar 29. 2011
15BRD7
BRD7 is a candidate tumour suppressor gene required for p53 function.
Drost J, Mantovani F, Tocco F, Elkon R, Comel A, Holstege H, Kerkhoven R, Jonkers J, Voorhoeve PM, Agami R, Del Sal G.
Nat Cell Biol 12(4):380-9. Epub 2010 Mar 14.PMID: 20228809 2010
16BRD7, PRDM1
Polybromo-associated BRG1-associated factor components BRD7 and BAF180 are critical regulators of p53 required for induction of replicative senescence.
Burrows AE, Smogorzewska A, Elledge SJ.
Proc Natl Acad Sci U S A 107(32):14280-5. Epub 2010 Jul 26. 2010
17BRCA1, BRD7
BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP.
Cancer Res 70(6):2538-47. Epub 2010 Mar 9. 2010
18BRD7, TRIM24
TRIM24 mediates ligand-dependent activation of androgen receptor and is repressed by a bromodomain-containing protein, BRD7, in prostate cancer cells.
Kikuchi M, Okumura F, Tsukiyama T, Watanabe M, Miyajima N, Tanaka J, Imamura M, Hatakeyama S.
Biochim Biophys Acta 1793(12):1828-36. Epub 2009 Nov 10. 2009
19BRD7, SMARCA4
BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells.
Kaeser MD, Aslanian A, Dong MQ, Yates JR 3rd, Emerson BM.
J Biol Chem 283(47):32254-63. Epub 2008 Sep 22. 2008
20BRD7
Transcriptional regulation of BRD7 expression by Sp1 and c-Myc.
Liu H, Zhou M, Luo X, Zhang L, Niu Z, Peng C, Ma J, Peng S, Zhou H, Xiang B, Li X, Li S, He J, Li X, Li G.
BMC Mol Biol 9:111. 2008
21BRD7
Promoter methylation inhibits BRD7 expression in human nasopharyngeal carcinoma cells.
Liu H, Zhang L, Niu Z, Zhou M, Peng C, Li X, Deng T, Shi L, Tan Y, Li G.
BMC Cancer 8:253. 2008
22ABL2, AKAP8, ANKRD13D, AP3D1, ARFGAP3, ARMCX6, ASUN, BAT2L, BCl2L13, BNIP3L, BPTF, BRD7, BZW1, BZW2, C12orf43, C19orf26, C1orf105, C2orf49, C6orf81, CA10, CAD, CARHSP1, CBX4, CCDC55, CCDC61, CCNK, CDC42BPB, CDC42EP3, CDC42EP4, CDS2, CENPN, CLK1, COPA, CSDA, CTPS2, DBN1, DCP1A, DECR2, DPF2, DPM1, EIF2AK1, EPB41L4A, EPN1, FAM91A1, FOSL2, FOXK1, GDF5OS, GFOD2, GIGYF2, GPATCH8, GTPBP1, HES7, HNRNPUL1, KIF1C, LPIN2, LRCH4, MAN2C1, MAST1, MED13, MED24, MED26, MINK1, MISP, MYO10, NKTR, OSBP, PAM, PCDH7, PEX14, PHF16, PHRF1, PLCB4, PLXNC1, POM121, POM121L2, PPHLN1, PRICKLE3, PRX, PUM2, RABGGTB, RBEL1, RIMS1, RIMS2, RPL14, RRP1B, RRP8, SAFB, SCAMP3, SCMH1, SCYL1, SENP6, SERBP1, SFRS13A, SFRS17A, SIPA1L1, SLC26A6, SLIRP, SLMAP, SNTA1, SORBS3, SPICE1, SSFA2, STAM, SUB1, TFIP11, TLN2, TMC6, TMEM104, TMEM106B, TMEM22, TOM1, UHRF1, UTP14A, WDR43, ZNF324, ZNF648
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.
Cell. 127(3):635-48. 2006
23BRD7
Cloning and characterization of the BRD7 gene promoter.
Liu H, Peng C, Zhou M, Zhou J, Shen S, Zhou H, Xiong W, Luo X, Peng S, Niu Z, Ouyang J, Li X, Li G.
DNA Cell Biol 25(6):346-58. 2006
24BRD7
The transcriptional regulation role of BRD7 by binding to acetylated histone through bromodomain.
Peng C, Zhou J, Liu HY, Zhou M, Wang LL, Zhang QH, Yang YX, Xiong W, Shen SR, Li XL, Li GY.
J Cell Biochem 97(4):882-92. 2006
25BRD2, BRD7
BRD2 is one of BRD7-interacting proteins and its over-expression could initiate apoptosis.
Zhou M, Xu XJ, Zhou HD, Liu HY, He JJ, Li XL, Peng C, Xiong W, Fan SQ, Lu JH, Ouyang J, Shen SR, Xiang B, Li GY.
Mol Cell Biochem 292(1-2):205-12. Epub 2006 Jun 20. 2006
26BRD7P3, BRD7
Identification and molecular characterization of BP75, a novel bromodomain-containing protein.
Cuppen E, van Ham M, Pepers B, Wieringa B, Hendriks W.
FEBS Lett 459(3):291-8. 1999