| 1 | BRCA1
|
| The functional impact of BRCA1 BRCT domain variants using multiplexed DNA double-strand break repair assays
|
| Adamovich AI, Diabate M, Banerjee T, Nagy G, Smith N, Duncan K, Mendoza Mendoza E, Prida G, Freitas MA, Starita LM, Parvin JD.
|
| Am J Hum Genet. Apr 7;109(4):618-630. doi: 10.1016/j.ajhg.2022.01.019. Epub 2022 Feb 22. 2022
|
| 2 | BARD1, BRCA1
|
| Structural insight into BRCA1-BARD1 complex recruitment to damaged chromatin.
|
| Dai L, Dai Y, Han J, Huang Y, Wang L, Huang J, Zhou Z.
|
| Mol Cell. Jul 1;81(13):2765-2777.e6. doi: 10.1016/j.molcel.2021.05.010. Epub 2021 Jun 7. 2021
|
| 3 | BARD1, BRCA1, SIRT2
|
| SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation.
|
| Minten EV, Kapoor-Vazirani P, Li C, Zhang H, Balakrishnan K, Yu DS.
|
| Cell Rep. Mar 30;34(13):108921. doi: 10.1016/j.celrep.2021.108921. 2021
|
| 4 | BARD1, BRCA1, TOP2B
|
| BRCA1-BARD1 regulates transcription through modulating topoisomerase IIβ.
|
| Bunch H, Jeong J, Kang K, Jo DS, Cong ATQ, Kim D, Kim D, Cho DH, Lee YM, Chen BPC, Schellenberg MJ, Calderwood SK.
|
| Open Biol. Oct;11(10):210221. doi: 10.1098/rsob.210221. Epub 2021 Oct 6. 2021
|
| 5 | BARD1, BRCA1
|
| The antitumorigenic roles of BRCA1-BARD1 in DNA repair and replication.
|
| Tarsounas M, Sung P.
|
| Nat Rev Mol Cell Biol. May;21(5):284-299. doi: 10.1038/s41580-020-0218-z. Epub 2020 Feb 24. 2020
|
| 6 | BARD1, BRCA1, OLA1, RACK1
|
| The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1
|
| Otsuka K, Yoshino Y, Qi H, Chiba N.
|
| Genes (Basel) Jul 24;11(8):842. doi: 10.3390/genes11080842. 2020
|
| 7 | ADAT2, BRCA1
|
| Uncovering the Translational Regulatory Activity of the Tumor Suppressor BRCA1
|
| Berthel E, Vincent A, Eberst L, Torres AG, Dacheux E, Rey C, Marcel V, Paraqindes H, Lachuer J, Catez F, Pouplana LR, Treilleux I, Diaz JJ, Venezia ND.
|
| Cells. Apr 10;9(4):941. doi: 10.3390/cells9040941. 2020
|
| 8 | BRCA1, GOT1, GOT2
|
| Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.
|
| Hong R, Zhang W, Xia X, Zhang K, Wang Y, Wu M, Fan J, Li J, Xia W, Xu F, Chen J, Wang S, Zhan Q.
|
| Mol Oncol 13(4):959-977. doi: 10.1002/1878-0261.12466. Epub 2019 Mar 1.
2019
|
| 9 | BARD1, BRCA1, OLA1, RACK1
|
| RACK1 regulates centriole duplication by controlling localization of BRCA1 to the centrosome in mammary tissue-derived cells
|
| Yoshino Y, Qi H, Kanazawa R, Sugamata M, Suzuki K, Kobayashi A, Shindo K, Matsuzawa A, Shibata S, Endo S, Miyanishi Y, Shimaoka T, Ishioka C, Kanno SI, Yasui A, Chiba N.
|
| Oncogene Apr;38(16):3077-3092. doi: 10.1038/s41388-018-0647-8. Epub 2019 Jan 7. 2019
|
| 10 | BRCA1, BRCA2
|
| Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches.
|
| Guidugli L, Shimelis H, Masica DL, Pankratz VS, Lipton GB, Singh N, Hu C, Monteiro ANA, Lindor NM, Goldgar DE, Karchin R, Iversen ES, Couch FJ.
|
| Am J Hum Genet m J Hum Genet. 2018 Jan 17. pii: S0002-9297(17)30502-5. doi: 10.1016/j.ajhg.2017.12.013. [Epub ahead of print]
2018
|
| 11 | BRCA1, BRCA2
|
| A Dominantly Inherited 5' UTR Variant Causing Methylation-Associated Silencing of BRCA1 as a Cause of Breast and Ovarian Cancer.
|
| Evans DGR, van Veen EM, Byers HJ, Wallace AJ, Ellingford JM, Beaman G, Santoyo-Lopez J, Aitman TJ, Eccles DM, Lalloo FI, Smith MJ, Newman WG.
|
| Am J Hum Genet 103(2):213-220. doi: 10.1016/j.ajhg.2018.07.002.
2018
|
| 12 | BRCA1, POU2F1
|
| BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism.
|
| Vázquez-Arreguín K, Maddox J, Kang J, Park D, Cano RR, Factor RE, Ludwig T, Tantin D.
|
| Mol Cancer Res 16(3):439-452. doi: 10.1158/1541-7786.MCR-17-0364. Epub 2018 Jan 12.
2018
|
| 13 | ACLY, BRCA1
|
| Nuclear Acetyl-CoA Production by ACLY Promotes Homologous Recombination.
|
| Sivanand S, Rhoades S, Jiang Q, Lee JV, Benci J, Zhang J, Yuan S, Viney I, Zhao S, Carrer A, Bennett MJ, Minn AJ, Weljie AM, Greenberg RA, Wellen KE.
|
| Mol Cell ol Cell. 2017 Jul 1. pii: S1097-2765(17)30435-5. doi: 10.1016/j.molcel.2017.06.008. [Epub ahead of print]
2017
|
| 14 | BRCA1, ZMYM3
|
| ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.
|
| Leung JW, Makharashvili N, Agarwal P, Chiu LY, Pourpre R, Cammarata MB, Cannon JR, Sherker A, Durocher D, Brodbelt JS, Paull TT, Miller KM.
|
| Genes Dev 31(3):260-274. doi: 10.1101/gad.292516.116. Epub 2017 Feb 27.
2017
|
| 15 | BARD1, BRCA1, RAD51
|
| BRCA1-BARD1 promotes RAD51-mediated homologous DNA pairing.
|
| Zhao W, Steinfeld JB, Liang F, Chen X, Maranon DG, Jian Ma C, Kwon Y, Rao T, Wang W, Sheng C, Song X, Deng Y, Jimenez-Sainz J, Lu L, Jensen RB, Xiong Y, Kupfer GM, Wiese C, Greene EC, Sung P.
|
| Nature. Oct 19;550(7676):360-365. doi: 10.1038/nature24060. Epub 2017 Oct 4. 2017
|
| 16 | BRCA1, FANCR, FANCS, FANCT, FANCU, FANCV, MAD2L2, RAD51, RAD51B, RAD51C, RAD51D, REV3L, UBE2T, XRCC2
|
| Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia.
|
| Mamrak NE, Shimamura A, Howlett NG.
|
| Blood Rev lood Rev. 2016 Oct 13. pii: S0268-960X(16)30054-6. doi: 10.1016/j.blre.2016.10.002. Review.
2016
|
| 17 | BRCA1, BRCA2, MDC1, RNF8, SLX4
|
| Elucidation of the Fanconi Anemia Protein Network in Meoisis and Its Function in the Regulation of Histone Modifications.
|
| Alavattam KG, Kato Y, Sin HS, Maezawa S, Kowalski IJ, Zhang F, Pang Q, Andreassen PR, Namekawa SH.
|
| Cell Rep 17(4):1141-1157. doi: 10.1016/j.celrep.2016.09.073.
2016
|
| 18 | BRCA1, BRCA2, ERCC5
|
| Non-catalytic Roles for XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability.
|
| Trego KS, Groesser T, Davalos AR, Parplys AC, Zhao W, Nelson MR, Hlaing A, Shih B, Rydberg B, Pluth JM, Tsai MS, Hoeijmakers JH, Sung P, Wiese C, Campisi J, Cooper PK.
|
| Mol Cell 61(4):535-46. doi: 10.1016/j.molcel.2015.12.026.
2016
|
| 19 | BRCA1, FAM175A
|
| Structure of BRCA1-BRCT/Abraxas Complex Reveals Phosphorylation-Dependent BRCT Dimerization at DNA Damage Sites.
|
| Wu Q, Paul A, Su D, Mehmood S, Foo TK, Ochi T, Bunting EL, Xia B, Robinson CV, Wang B, Blundell TL.
|
| Mol Cell 61(3):434-48. doi: 10.1016/j.molcel.2015.12.017.
2016
|
| 20 | BRCA1, CEP72, CHEK2
|
| The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.
|
| Lüddecke S, Ertych N, Stenzinger A, Weichert W, Beissbarth T, Dyczkowski J, Gaedcke J, Valerius O, Braus GH, Kschischo M, Bastians H.
|
| Oncogene 35(18):2398-406. doi: 10.1038/onc.2015.290. 2016
|
| 21 | AURKA, BRCA1, CHEK2
|
| CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.
|
| Ertych N, Stolz A, Valerius O, Braus GH, Bastians H.
|
| Proc Natl Acad Sci U S A 113(7):1817-22. doi: 10.1073/pnas.1525129113. Epub 2016 Feb 1.
2016
|
| 22 | BRCA1, BRCA2, FANCA, FANCD2, FANCF, FANCL
|
| Fanconi Anemia Proteins Function in Mitophagy and Immunity
|
| Sumpter R Jr, Sirasanagandla S, Fernández ÁF, Wei Y, Dong X, Franco L, Zou Z, Marchal C, Lee MY, Clapp DW, Hanenberg H, Levine B.
|
| Cell. May 5;165(4):867-81. doi: 10.1016/j.cell.2016.04.006. Epub 2016 Apr 28. 2016
|
| 23 | BARD1, BRCA1
|
| New concepts on BARD1: Regulator of BRCA pathways and beyond
|
| Irminger-Finger I, Ratajska M, Pilyugin M.
|
| Int J Biochem Cell Biol Mar;72:1-17. doi: 10.1016/j.biocel.2015.12.008. Epub 2015 Dec 29. 2016
|
| 24 | BRCA1, TP53BP1, USP51
|
| USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.
|
| Wang Z, Zhang H, Liu J, Cheruiyot A, Lee JH, Ordog T, Lou Z, You Z, Zhang Z.
|
| Genes Dev. Apr 15;30(8):946-59. doi: 10.1101/gad.271841.115. 2016
|
| 25 | BRCA1, E2F4, RAD17
|
| Gain of function mutant p53 proteins cooperate with E2F4 to transcriptionally downregulate RAD17 and BRCA1 gene expression.
|
| Valenti F, Ganci F, Fontemaggi G, Sacconi A, Strano S, Blandino G, Di Agostino S.
|
| Oncotarget 6(8):5547-66.
2015
|
| 26 | BABAM1, BRCA1, BRCA2
|
| MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links.
|
| Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman MM, Greenberg RA.
|
| Genes Dev 29(18):1955-68. doi: 10.1101/gad.264192.115.
2015
|
| 27 | BRCA1, FAM175A
|
| BRCA1 Is Required for Maintenance of Phospho-Chk1 and G2/M Arrest during DNA Cross-Link Repair in DT40 Cells.
|
| Draga M, Madgett EB, Vandenberg CJ, du Plessis D, Kaufmann A, Werler P, Chakraborty P, Lowndes NF, Hiom K.
|
| Mol Cell Biol 35(22):3829-40. doi: 10.1128/MCB.01497-14.
2015
|
| 28 | BRCA1, FAM175A
|
| Mislocalization of BRCA1-complex due to ABRAXAS Arg361Gln mutation.
|
| Vikrant, Kumar R, Siddiqui Q, Singh N, Waghmare SK, Varma AK.
|
| J Biomol Struct Dyn 33(6):1291-301. doi: 10.1080/07391102.2014.945484.
2015
|
| 29 | BRCA1, NPRL2
|
| TUSC4 functions as a tumor suppressor by regulating BRCA1 stability.
|
| Peng Y, Dai H, Wang E, Lin CC, Mo W, Peng G, Lin SY.
|
| Cancer Res 75(2):378-86. doi: 10.1158/0008-5472.CAN-14-2315. Epub 2014 Dec 5.
2015
|
| 30 | BRCA1, TP53BP1
|
| Double-strand break repair: 53BP1 comes into focus.
|
| Panier S, Boulton SJ.
|
| Nat Rev Mol Cell Biol 15(1):7-18. doi: 10.1038/nrm3719. Epub 2013 Dec 11. Review.
2014
|
| 31 | BRCA1, CHEK1, FANCD2
|
| BRCA1, FANCD2 and Chk1 are potential molecular targets for the modulation of a radiation-induced DNA damage response in bystander cells.
|
| Burdak-Rothkamm S, Rothkamm K, McClelland K, Rashid ST, Prise KM.
|
| Cancer Lett ancer Lett. 2014 Oct 7. pii: S0304-3835(14)00584-9. doi: 10.1016/j.canlet.2014.09.043. [Epub ahead of print]
2014
|
| 32 | BLM, BRCA1, RAD50
|
| Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells.
|
| Acharya S, Kaul Z, Gocha AS, Martinez AR, Harris J, Parvin JD, Groden J.
|
| PLoS One 9(8):e103819. doi: 10.1371/journal.pone.0103819. eCollection 2014.
2014
|
| 33 | BRCA1, BRIP1, PLK1
|
| BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1.
|
| Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D.
|
| Cell Cycle 13(23):3685-97. doi: 10.4161/15384101.2014.964973.
2014
|
| 34 | BRCA1, BRCA2
|
| Rapid evolution of BRCA1 and BRCA2 in humans and other primates.
|
| Lou DI, McBee RM, Le UQ, Stone AC, Wilkerson GK, Demogines AM, Sawyer SL.
|
| BMC Evol Biol 14:155. doi: 10.1186/1471-2148-14-155.
2014
|
| 35 | BRCA1, FAM175A
|
| The BRCA1-interacting protein Abraxas is required for genomic stability and tumor suppression.
|
| Castillo A, Paul A, Sun B, Huang TH, Wang Y, Yazinski SA, Tyler J, Li L, You MJ, Zou L, Yao J, Wang B.
|
| Cell Rep 8(3):807-17. doi: 10.1016/j.celrep.2014.06.050.
2014
|
| 36 | BRCA1, HUWE1
|
| HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin-proteasome pathway.
|
| Wang X, Lu G, Li L, Yi J, Yan K, Wang Y, Zhu B, Kuang J, Lin M, Zhang S, Shao G.
|
| Biochem Biophys Res Commun 444(4):549-54. doi: 10.1016/j.bbrc.2014.01.075. Epub 2014 Jan 25.
2014
|
| 37 | BARD1, BRCA1, OLA1
|
| OLA1 in centrosome biology alongside the BRCA1/BARD1 complex: looking beyond centrosomes.
|
| Gomez V, Hergovich A.
|
| Mol Cell. Jan 9;53(1):3-5. doi: 10.1016/j.molcel.2013.12.016. 2014
|
| 38 | BARD1, BRCA1, OLA1
|
| The BRCA1/BARD1-interacting protein OLA1 functions in centrosome regulation.
|
| Matsuzawa A, Kanno S, Nakayama M, Mochiduki H, Wei L, Shimaoka T, Furukawa Y, Kato K, Shibata S, Yasui A, Ishioka C, Chiba N.
|
| Mol Cell. Jan 9;53(1):101-14. doi: 10.1016/j.molcel.2013.10.028. Epub 2013 Nov 27. 2014
|
| 39 | BARD1, BRCA1, CDC25C
|
| BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation.
|
| Shabbeer S, Omer D, Berneman D, Weitzman O, Alpaugh A, Pietraszkiewicz A, Metsuyanim S, Shainskaya A, Papa MZ, Yarden RI.
|
| Oncogene 32(42):5005-16. doi: 10.1038/onc.2012.522. Epub 2012 Dec 17.
2013
|
| 40 | BRCA1, CTSL, TP53
|
| BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells.
|
| Grotsky DA, Gonzalez-Suarez I, Novell A, Neumann MA, Yaddanapudi SC, Croke M, Martinez-Alonso M, Redwood AB, Ortega-Martinez S, Feng Z, Lerma E, Ramon y Cajal T, Zhang J, Matias-Guiu X, Dusso A, Gonzalo S.
|
| J Cell Biol 200(2):187-202. doi: 10.1083/jcb.201204053. 2013
|
| 41 | AURKA, BORA, BRCA1, PLK1
|
| BRCA1 downregulates the kinase activity of Polo-like kinase 1 in response to replication stress.
|
| Zou J, Rezvani K, Wang H, Lee KS, Zhang D.
|
| Cell Cycle 12(14):2255-65. doi: 10.4161/cc.25349.
2013
|
| 42 | BRCA1, TP53BP1
|
| Differences in 53BP1 and BRCA1 regulation between cycling and non-cycling cells.
|
| Croke M, Neumann MA, Grotsky DA, Kreienkamp R, Yaddanapudi SC, Gonzalo S.
|
| Cell Cycle 12(23):3629-39. doi: 10.4161/cc.26582. Epub 2013 Oct 2.
2013
|
| 43 | BRCA1, NBN, RBBP8
|
| The interaction of CtIP and Nbs1 connects CDK and ATM to regulate HR-mediated double-strand break repair.
|
| Wang H, Shi LZ, Wong CC, Han X, Hwang PY, Truong LN, Zhu Q, Shao Z, Chen DJ, Berns MW, Yates JR 3rd, Chen L, Wu X.
|
| PLoS Genet 9(2):e1003277. doi: 10.1371/journal.pgen.1003277. Epub 2013 Feb 28.
2013
|
| 44 | BRCA1, ZNF423
|
| Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
|
| Ingle JN, Liu M, Wickerham DL, Schaid DJ, Wang L, Mushiroda T, Kubo M, Costantino JP, Vogel VG, Paik S, Goetz MP, Ames MM, Jenkins GD, Batzler A, Carlson EE, Flockhart DA, Wolmark N, Nakamura Y, Weinshilboum RM.
|
| Cancer Discov 3(7):812-25. doi: 10.1158/2159-8290.CD-13-0038. Epub 2013 Jun 13.
2013
|
| 45 | BRCA1, FAM175A
|
| Preliminary crystallographic studies of BRCA1 BRCT-ABRAXAS complex.
|
| Badgujar DC, Sawant U; Vikrant.
|
| Acta Crystallogr Sect F Struct Biol Cryst Commun 69(Pt 12):1401-4. doi: 10.1107/S1744309113030649.
2013
|
| 46 | BRCA1, DCLRE1B, FANCD2
|
| The SNM1B/APOLLO DNA nuclease functions in resolution of replication stress and maintenance of common fragile site stability.
|
| Mason JM, Das I, Arlt M, Patel N, Kraftson S, Glover TW, Sekiguchi JM.
|
| Hum Mol Genet 22(24):4901-13. doi: 10.1093/hmg/ddt340. Epub 2013 Jul 17.
2013
|
| 47 | BRCA1, SMARCA4
|
| BRG1 is required for formation of senescence-associated heterochromatin foci induced by oncogenic RAS or BRCA1 loss
|
| Tu Z, Zhuang X, Yao YG, Zhang R.
|
| Mol Cell Biol. May;33(9):1819-29. doi: 10.1128/MCB.01744-12. Epub 2013 Feb 25. 2013
|
| 48 | BRCA1, HSP90AA1
|
| BRCA1 and HSP90 cooperate in homologous and non-homologous DNA double-strand-break repair and G2/M checkpoint activation.
|
| Stecklein SR, Kumaraswamy E, Behbod F, Wang W, Chaguturu V, Harlan-Williams LM, Jensen RA.
|
| Proc Natl Acad Sci U S A 109(34):13650-5. doi: 10.1073/pnas.1203326109. Epub 2012 Aug 6.
2012
|
| 49 | BRCA1, CLASP1
|
| A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair.
|
| Sato K, Sundaramoorthy E, Rajendra E, Hattori H, Jeyasekharan AD, Ayoub N, Schiess R, Aebersold R, Nishikawa H, Sedukhina AS, Wada H, Ohta T, Venkitaraman AR.
|
| Curr Biol 22(18):1659-66. doi: 10.1016/j.cub.2012.07.034. Epub 2012 Aug 2.
2012
|
| 50 | BRCA1
|
| Germline BRCA1 mutations increase prostate cancer risk.
|
| Leongamornlert D, Mahmud N, Tymrakiewicz M, Saunders E, Dadaev T, Castro E, Goh C, Govindasami K, Guy M, O'Brien L, Sawyer E, Hall A, Wilkinson R, Easton D; UKGPCS Collaborators, Goldgar D, Eeles R, Kote-Jarai Z.
|
| Br J Cancer 106(10):1697-701.
2012
|
| 51 | BRCA1
|
| BRCA1 regulates microRNA biogenesis via the DROSHA microprocessor complex.
|
| Kawai S, Amano A.
|
| J Cell Biol 197(2):201-8. doi: 10.1083/jcb.201110008. Epub 2012 Apr 9.
2012
|
| 52 | BRCA1
|
| BRCA1 functions independently of homologous recombination in DNA interstrand crosslink repair.
|
| Bunting SF, Callén E, Kozak ML, Kim JM, Wong N, López-Contreras AJ, Ludwig T, Baer R, Faryabi RB, Malhowski A, Chen HT, Fernandez-Capetillo O, D'Andrea A, Nussenzweig A.
|
| Mol Cell 46(2):125-35. Epub 2012 Mar 22.
2012
|
| 53 | BRCA1
|
| The C-terminal proteolytic fragment of the breast cancer susceptibility type 1 protein (BRCA1) is degraded by the N-end rule pathway.
|
| Xu Z, Payoe R, Fahlman RP.
|
| J Biol Chem 287(10):7495-502. Epub 2012 Jan 18.
2012
|
| 54 | BARD1, BRCA1
|
| BARD1: an independent predictor of survival in non-small cell lung cancer.
|
| Zhang YQ, Bianco A, Malkinson AM, Leoni VP, Frau G, De Rosa N, André PA, Versace R, Boulvain M, Laurent GJ, Atzori L, Irminger-Finger I.
|
| Int J Cancer 131(1):83-94. doi: 10.1002/ijc.26346. Epub 2011 Dec 21.
2012
|
| 55 | ATM, BRCA1, E2F1, RBBP8
|
| Dynamic coregulatory complex containing BRCA1, E2F1 and CtIP controls ATM transcription.
|
| Moiola C, De Luca P, Cotignola J, Gardner K, Vazquez E, De Siervi A.
|
| Cell Physiol Biochem 30(3):596-608. doi: 10.1159/000341441. Epub 2012 Jul 27.
2012
|
| 56 | BRCA1, CRIM1
|
| Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase.
|
| Brodie KM, Henderson BR.
|
| J Biol Chem. 287(10):7701-16. 2012
|
| 57 | BRCA1, YY1
|
| Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation.
|
| Lee MH, Lahusen T, Wang RH, Xiao C, Xu X, Hwang YS, He WW, Shi Y, Deng CX.
|
| Oncogene 31(1):116-27. doi: 10.1038/onc.2011.217. Epub 2011 Jun 13.
2012
|
| 58 | BRCA1
|
| Functional differences among BRCA1 missense mutations in the control of centrosome duplication.
|
| Kais Z, Chiba N, Ishioka C, Parvin JD.
|
| Oncogene 31(6):799-804. doi: 10.1038/onc.2011.271. Epub 2011 Jul 4.
2012
|
| 59 | BRCA1, FBXO44, SKP1
|
| The F-box protein FBXO44 mediates BRCA1 ubiquitination and degradation.
|
| Lu Y, Li J, Cheng D, Parameswaran B, Zhang S, Jiang Z, Yew PR, Peng J, Ye Q, Hu Y.
|
| J Biol Chem 287(49):41014-22. doi: 10.1074/jbc.M112.407106. Epub 2012 Oct 18.
2012
|
| 60 | BRCA1, RNF8, TP53BP1
|
| RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.
|
| Nakada S, Yonamine RM, Matsuo K.
|
| Cancer Res 72(19):4974-83. doi: 10.1158/0008-5472.CAN-12-1057. Epub 2012 Aug 3.
2012
|
| 61 | BRCA1, TP53BP1
|
| BRCA1-associated exclusion of 53BP1 from DNA damage sites underlies temporal control of DNA repair.
|
| Chapman JR, Sossick AJ, Boulton SJ, Jackson SP.
|
| J Cell Sci 125(Pt 15):3529-34. Epub 2012 May 2.
2012
|
| 62 | BRCA1, GATA3
|
| BRCA1 and GATA3 corepress FOXC1 to inhibit the pathogenesis of basal-like breast cancers.
|
| Tkocz D, Crawford NT, Buckley NE, Berry FB, Kennedy RD, Gorski JJ, Harkin DP, Mullan PB.
|
| Oncogene 31(32):3667-78. doi: 10.1038/onc.2011.531. Epub 2011 Nov 28.
2012
|
| 63 | BRCA1, RNF168, TP53BP1
|
| RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1.
|
| Muñoz MC, Laulier C, Gunn A, Cheng A, Robbiani DF, Nussenzweig A, Stark JM.
|
| J Biol Chem 287(48):40618-28. doi: 10.1074/jbc.M112.410951. Epub 2012 Oct 10.
2012
|
| 64 | BRCA1, UIMC1
|
| RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci.
|
| Hu Y, Scully R, Sobhian B, Xie A, Shestakova E, Livingston DM.
|
| Genes Dev 25(7):685-700. Epub 2011 Mar 15.
2011
|
| 65 | BRCA1, UIMC1
|
| The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection.
|
| Coleman KA, Greenberg RA.
|
| J Biol Chem 286(15):13669-80. Epub 2011 Feb 18.
2011
|
| 66 | BCL2, BRCA1
|
| Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes.
|
| Laulier C, Barascu A, Guirouilh-Barbat J, Pennarun G, Le Chalony C, Chevalier F, Palierne G, Bertrand P, Verbavatz JM, Lopez BS.
|
| Cancer Res 71(10):3590-602. Epub 2011 Mar 28.
2011
|
| 67 | BRCA1
|
| Hypoxia-induced epigenetic regulation and silencing of the BRCA1 promoter.
|
| Lu Y, Chu A, Turker MS, Glazer PM.
|
| Mol Cell Biol 31(16):3339-50. Epub 2011 Jun 13.
2011
|
| 68 | BRCA1, TUBG1
|
| Cdk1 and BRCA1 target γ-tubulin to microtubule domains.
|
| Hubert T, Vandekerckhove J, Gettemans J.
|
| Biochem Biophys Res Commun 414(1):240-5. Epub 2011 Sep 17.
2011
|
| 69 | BRCA1
|
| BRCA1 tumour suppression occurs via heterochromatin-mediated silencing.
|
| Zhu Q, Pao GM, Huynh AM, Suh H, Tonnu N, Nederlof PM, Gage FH, Verma IM.
|
| Nature 477(7363):179-84. doi: 10.1038/nature10371.
2011
|
| 70 | BRCA1
|
| BRCA1 is required for postreplication repair after UV-induced DNA damage.
|
| Pathania S, Nguyen J, Hill SJ, Scully R, Adelmant GO, Marto JA, Feunteun J, Livingston DM.
|
| Mol Cell 44(2):235-51. doi: 10.1016/j.molcel.2011.09.002. Epub 2011 Sep 29.
2011
|
| 71 | BRCA1, MIR155
|
| Tumor suppressor BRCA1 epigenetically controls oncogenic microRNA-155.
|
| Chang S, Wang RH, Akagi K, Kim KA, Martin BK, Cavallone L; Kathleen Cuningham Foundation Consortium for Research into Familial Breast Cancer (kConFab), Haines DC, Basik M, Mai P, Poggi E, Isaacs C, Looi LM, Mun KS, Greene MH, Byers SW, Teo SH, Deng CX, Sharan SK.
|
| Nat Med 17(10):1275-82. doi: 10.1038/nm.2459. Erratum in: Nat Med. 2011 Oct;17(10):2 p following 1282. Nat Med. 2011 Nov;17(11):1521.
2011
|
| 72 | BARD1, BRCA1, BRCA2, BRIP1, CHEK2, MRE11A, MSH6, NBN, PALB2, RAD50, RAD51c, TP53
|
| Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.
|
| Walsh T, Casadei S, Lee MK, Pennil CC, Nord AS, Thornton AM, Roeb W, Agnew KJ, Stray SM, Wickramanayake A, Norquist B, Pennington KP, Garcia RL, King MC, Swisher EM.
|
| Proc Natl Acad Sci U S A 108(44):18032-7. doi: 10.1073/pnas.1115052108. Epub 2011 Oct 17.
2011
|
| 73 | BRCA1
|
| BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity.
|
| Shakya R, Reid LJ, Reczek CR, Cole F, Egli D, Lin CS, deRooij DG, Hirsch S, Ravi K, Hicks JB, Szabolcs M, Jasin M, Baer R, Ludwig T.
|
| Science 334(6055):525-8. doi: 10.1126/science.1209909.
2011
|
| 74 | BRCA1, UBE2I
|
| Ubc9 mediates nuclear localization and growth suppression of BRCA1 and BRCA1a proteins.
|
| Qin Y, Xu J, Aysola K, Begum N, Reddy V, Chai Y, Grizzle WE, Partridge EE, Reddy ES, Rao VN.
|
| J Cell Physiol 226(12):3355-67. doi: 10.1002/jcp.22695.
2011
|
| 75 | BRCA1
|
| Profiling of the BRCA1 transcriptome through microarray and ChIP-chip analysis.
|
| Gorski JJ, Savage KI, Mulligan JM, McDade SS, Blayney JK, Ge Z, Harkin DP.
|
| Nucleic Acids Res. 39(22):9536-48 2011
|
| 76 | BRCA1
|
| Common variants of the BRCA1 wild-type allele modify the risk of breast cancer in BRCA1 mutation carriers.
|
| Cox DG, Simard J, Sinnett D, Hamdi Y, Soucy P, Ouimet M, Barjhoux L, Verny-Pierre C, McGuffog L, Healey S, Szabo C, Greene MH, Mai PL, Andrulis IL; Ontario Cancer Genetics Network, Thomassen M, Gerdes AM, Caligo MA, Friedman E, Laitman Y, Kaufman B, Paluch SS, Borg Å, Karlsson P, Askmalm MS, Bustinza GB; SWE-BRCA Collaborators, Nathanson KL, Domchek SM, Rebbeck TR, Benítez J, Hamann U, Rookus MA, van den Ouweland AM, Ausems MG, Aalfs CM, van Asperen CJ, Devilee P, Gille HJ; HEBON; EMBRACE, Peock S, Frost D, Evans DG, Eeles R, Izatt L, Adlard J, Paterson J, Eason J, Godwin AK, Remon MA, Moncoutier V, Gauthier-Villars M, Lasset C, Giraud S, Hardouin A, Berthet P, Sobol H, Eisinger F, Bressac de Paillerets B, Caron O, Delnatte C; GEMO Study Collaborators, Goldgar D, Miron A, Ozcelik H, Buys S, Southey MC, Terry MB; Breast Cancer Family Registry, Singer CF, Dressler AC, Tea MK, Hansen TV, Johannsson O, Piedmonte M, Rodriguez GC, Basil JB, Blank S, Toland AE, Montagna M, Isaacs C, Blanco I, Gayther SA, Moysich KB, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Ditsch N, Arnold N, Niederacher D, Sutter C, Gadzicki D, Fiebig B, Caldes T, Laframboise R, Nevanlinna H, Chen X, Beesley J, Spurdle AB, Neuhausen SL, Ding YC, Couch FJ, Wang X, Peterlongo P, Manoukian S, Bernard L, Radice P, Easton DF, Chenevix-Trench G, Antoniou AC, Stoppa-Lyonnet D, Mazoyer S, Sinilnikova OM; Consortium of Investigators of Modifiers of BRCA1/2.
|
| Hum Mol Genet 20(23):4732-47. doi: 10.1093/hmg/ddr388. Epub 2011 Sep 2.
2011
|
| 77 | BRCA1
|
| BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein.
|
| Wei L, Lan L, Yasui A, Tanaka K, Saijo M, Matsuzawa A, Kashiwagi R, Maseki E, Hu Y, Parvin JD, Ishioka C, Chiba N.
|
| Cancer Sci. 102(10):1840-7. 2011
|
| 78 | BRCA1
|
| Multifunctional transcription factor TFII-I is an activator of BRCA1 function.
|
| Tanikawa M, Wada-Hiraike O, Nakagawa S, Shirane A, Hiraike H, Koyama S, Miyamoto Y, Sone K, Tsuruga T, Nagasaka K, Matsumoto Y, Ikeda Y, Shoji K, Oda K, Fukuhara H, Nakagawa K, Kato S, Yano T, Taketani Y.
|
| Br J Cancer. 104(8):1349-55. 2011
|
| 79 | BRCA1
|
| KIAA0101 interacts with BRCA1 and regulates centrosome number.
|
| Kais Z, Barsky SH, Mathsyaraja H, Zha A, Ransburgh DJ, He G, Pilarski RT, Shapiro CL, Huang K, Parvin JD.
|
| Mol Cancer Res. 9(8):1091-9. 2011
|
| 80 | BRCA1
|
| BRCA1 and its toolbox for the maintenance of genome integrity.
|
| Huen MS, Sy SM, Chen J.
|
| Nat Rev Mol Cell Biol 11(2):138-48. Epub 2009 Dec 23. Review.PMID: 20029420 2010
|
| 81 | BRCA1, SERPINB5
|
| BRCA1 185delAG mutant protein, BRAt, up-regulates maspin in ovarian epithelial cells.
|
| O'Donnell JD, Linger RJ, Kruk PA.
|
| Gynecol Oncol 116(2):262-8. Epub 2009 Nov 10.
2010
|
| 82 | BRCA1, LIG4, TP53BP1
|
| 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
|
| Bunting SF, Callén E, Wong N, Chen HT, Polato F, Gunn A, Bothmer A, Feldhahn N, Fernandez-Capetillo O, Cao L, Xu X, Deng CX, Finkel T, Nussenzweig M, Stark JM, Nussenzweig A.
|
| Cell 141(2):243-54. Epub 2010 Apr 1.
2010
|
| 83 | BRCA1, BRIP1
|
| Targeting the FANCJ-BRCA1 interaction promotes a switch from recombination to poleta-dependent bypass.
|
| Xie J, Litman R, Wang S, Peng M, Guillemette S, Rooney T, Cantor SB.
|
| Oncogene 29(17):2499-508. Epub 2010 Feb 22.
2010
|
| 84 | BARD1, BRCA1, ETV5, SRSF1, UBXN1
|
| Etv5 Regulates Sertoli Cell Chemokines Involved in Mouse Stem/Progenitor Spermatogonia Maintenance.
|
| Simon L, Ekman GC, Garcia T, Carnes K, Zhang Z, Murphy T, Murphy KM, Hess RA, Cooke PS, Hofmann MC.
|
| Stem Cells Stem Cells. 2010 Aug 26. [Epub ahead of print] 2010
|
| 85 | BARD1, BRCA1, UBXN1
|
| The UBXN1 protein associates with autoubiquitinated forms of the BRCA1 tumor suppressor and inhibits its enzymatic function.
|
| Wu-Baer F, Ludwig T, Baer R.
|
| Mol Cell Biol 30(11):2787-98. Epub 2010 Mar 29.PMID: 20351172 2010
|
| 86 | BRCA1
|
| GWAS identifies a common breast cancer risk allele among BRCA1 carriers.
|
| Kraft P, Haiman CA.
|
| Nat Genet 42(10):819-20. No abstract available.
2010
|
| 87 | BRCA1
|
| A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.
|
| Antoniou AC, Wang X, Fredericksen ZS, McGuffog L, Tarrell R, Sinilnikova OM, Healey S, Morrison J, Kartsonaki C, Lesnick T, Ghoussaini M, Barrowdale D; EMBRACE, Peock S, Cook M, Oliver C, Frost D, Eccles D, Evans DG, Eeles R, Izatt L, Chu C, Douglas F, Paterson J, Stoppa-Lyonnet D, Houdayer C, Mazoyer S, Giraud S, Lasset C, Remenieras A, Caron O, Hardouin A, Berthet P; GEMO Study Collaborators, Hogervorst FB, Rookus MA, Jager A, van den Ouweland A, Hoogerbrugge N, van der Luijt RB, Meijers-Heijboer H, Gómez García EB; HEBON, Devilee P, Vreeswijk MP, Lubinski J, Jakubowska A, Gronwald J, Huzarski T, Byrski T, Górski B, Cybulski C, Spurdle AB, Holland H; kConFab, Goldgar DE, John EM, Hopper JL, Southey M, Buys SS, Daly MB, Terry MB, Schmutzler RK, Wappenschmidt B, Engel C, Meindl A, Preisler-Adams S, Arnold N, Niederacher D, Sutter C, Domchek SM, Nathanson KL, Rebbeck T, Blum JL, Piedmonte M, Rodriguez GC, Wakeley K, Boggess JF, Basil J, Blank SV, Friedman E, Kaufman B, Laitman Y, Milgrom R, Andrulis IL, Glendon G, Ozcelik H, Kirchhoff T, Vijai J, Gaudet MM, Altshuler D, Guiducci C; SWE-BRCA, Loman N, Harbst K, Rantala J, Ehrencrona H, Gerdes AM, Thomassen M, Sunde L, Peterlongo P, Manoukian S, Bonanni B, Viel A, Radice P, Caldes T, de la Hoya M, Singer CF, Fink-Retter A, Greene MH, Mai PL, Loud JT, Guidugli L, Lindor NM, Hansen TV, Nielsen FC, Blanco I, Lazaro C, Garber J, Ramus SJ, Gayther SA, Phelan C, Narod S, Szabo CI; MOD SQUAD, Benitez J, Osorio A, Nevanlinna H, Heikkinen T, Caligo MA, Beattie MS, Hamann U, Godwin AK, Montagna M, Casella C, Neuhausen SL, Karlan BY, Tung N, Toland AE, Weitzel J, Olopade O, Simard J, Soucy P, Rubinstein WS, Arason A, Rennert G, Martin NG, Montgomery GW, Chang-Claude J, Flesch-Janys D, Brauch H; GENICA, Severi G, Baglietto L, Cox A, Cross SS, Miron P, Gerty SM, Tapper W, Yannoukakos D, Fountzilas G, Fasching PA, Beckmann MW, Dos Santos Silva I, Peto J, Lambrechts D, Paridaens R, Rüdiger T, Försti A, Winqvist R, Pylkäs K, Diasio RB, Lee AM, Eckel-Passow J, Vachon C, Blows F, Driver K, Dunning A, Pharoah PP, Offit K, Pankratz VS, Hakonarson H, Chenevix-Trench G, Easton DF, Couch FJ.
|
| Nat Genet 42(10):885-92. Epub 2010 Sep 19.
2010
|
| 88 | BRCA1
|
| Transcriptional regulation of BRCA1 expression by a metabolic switch.
|
| Di LJ, Fernandez AG, De Siervi A, Longo DL, Gardner K.
|
| Nat Struct Mol Biol 17(12):1406-13. Epub 2010 Nov 21.
2010
|
| 89 | BRCA1, CTBP1
|
| Redox-dependent Brca1 transcriptional regulation by an NADH-sensor CtBP1.
|
| Deng Y, Liu J, Han G, Lu SL, Wang SY, Malkoski S, Tan AC, Deng C, Wang XJ, Zhang Q.
|
| Oncogene 29(50):6603-8. Epub 2010 Sep 6.
2010
|
| 90 | BRCA1, BRD7
|
| BRD7, a subunit of SWI/SNF complexes, binds directly to BRCA1 and regulates BRCA1-dependent transcription.
|
| Harte MT, O'Brien GJ, Ryan NM, Gorski JJ, Savage KI, Crawford NT, Mullan PB, Harkin DP.
|
| Cancer Res 70(6):2538-47. Epub 2010 Mar 9.
2010
|
| 91 | BRCA1
|
| HERC2 is an E3 ligase that targets BRCA1 for degradation.
|
| Wu W, Sato K, Koike A, Nishikawa H, Koizumi H, Venkitaraman AR, Ohta T.
|
| Cancer Res. 70(15):6384-92. 2010
|
| 92 | BRCA1
|
| Identification of DBC1 as a transcriptional repressor for BRCA1.
|
| Hiraike H, Wada-Hiraike O, Nakagawa S, Koyama S, Miyamoto Y, Sone K, Tanikawa M, Tsuruga T, Nagasaka K, Matsumoto Y, Oda K, Shoji K, Fukuhara H, Saji S, Nakagawa K, Kato S, Yano T, Taketani Y.
|
| Br J Cancer. 102(6):1061-7. 2010
|
| 93 | BRCA1
|
| MRG15 binds directly to PALB2 and stimulates homology-directed repair of chromosomal breaks.
|
| Hayakawa T, Zhang F, Hayakawa N, Ohtani Y, Shinmyozu K, Nakayama J, Andreassen PR.
|
| J Cell Sci. 123(Pt 7):1124-30. 2010
|
| 94 | BRCA1
|
| Methylation of the tumor suppressor protein, BRCA1, influences its transcriptional cofactor function.
|
| Guendel I, Carpio L, Pedati C, Schwartz A, Teal C, Kashanchi F, Kehn-Hall K.
|
| PLoS One. 5(6):e11379. 2010
|
| 95 | BRCA1
|
| Ubiquitination and downregulation of BRCA1 by ubiquitin-conjugating enzyme E2T overexpression in human breast cancer cells.
|
| Ueki T, Park JH, Nishidate T, Kijima K, Hirata K, Nakamura Y, Katagiri T.
|
| Cancer Res. 69(22):8752-60. 2009
|
| 96 | BRCA1, BRCA2, PALB2
|
| PALB2 is an integral component of the BRCA complex required for homologous recombination repair.
|
| Sy SM, Huen MS, Chen J.
|
| Proc Natl Acad Sci U S A 106(17):7155-60. Epub 2009 Apr 15.
2009
|
| 97 | BABAM1, BRCA1, BRE, FAM175A, UIMC1
|
| MERIT40 facilitates BRCA1 localization and DNA damage repair.
|
| Feng L, Huang J, Chen J.
|
| Genes Dev 23(6):719-28. Epub 2009 Mar 4. 2009
|
| 98 | BABAM1, BRCA1
|
| NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.
|
| Wang B, Hurov K, Hofmann K, Elledge SJ.
|
| Genes Dev 23(6):729-39. Epub 2009 Mar 4. 2009
|
| 99 | BABAM1, BRCA1, BRE, FAM175A, UIMC1
|
| MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.
|
| Shao G, Patterson-Fortin J, Messick TE, Feng D, Shanbhag N, Wang Y, Greenberg RA.
|
| Genes Dev 23(6):740-54. Epub 2009 Mar 4. 2009
|
| 100 | BRCA1, EZH2
|
| Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1.
|
| Gonzalez ME, Li X, Toy K, DuPrie M, Ventura AC, Banerjee M, Ljungman M, Merajver SD, Kleer CG.
|
| Oncogene 28(6):843-53. Epub 2008 Dec 15.
2009
|
| 101 | BABAM1, BRCA1, BRE, UIMC1
|
| Mutation screening of the MERIT40 gene encoding a novel BRCA1 and RAP80 interacting protein in breast cancer families.
|
| Solyom S, Patterson-Fortin J, Pylkäs K, Greenberg RA, Winqvist R.
|
| Breast Cancer Res Treat reast Cancer Res Treat. 2009 Jul 2. [Epub ahead of print] 2009
|
| 102 | BRCA1, NINL
|
| BRCA1 Interaction of Centrosomal Protein Nlp Is Required for Successful Mitotic Progression.
|
| Jin S, Gao H, Mazzacurati L, Wang Y, Fan W, Chen Q, Yu W, Wang M, Zhu X, Zhang C, Zhan Q.
|
| J Biol Chem 284(34):22970-7. Epub 2009 Jun 9.
2009
|
| 103 | BRCA1
|
| BRCA1 localization to the telomere and its loss from the telomere in response to DNA damage.
|
| Ballal RD, Saha T, Fan S, Haddad BR, Rosen EM.
|
| J Biol Chem 284(52):36083-98. Epub 2009 Sep 21.PMID: 19797051 2009
|
| 104 | BRCA1
|
| BRCA1 interaction of centrosomal protein Nlp is required for successful mitotic progression.
|
| Jin S, Gao H, Mazzacurati L, Wang Y, Fan W, Chen Q, Yu W, Wang M, Zhu X, Zhang C, Zhan Q.
|
| J Biol Chem. 284(34):22970-7. 2009
|
| 105 | BRCA1
|
| BRCA1 interacts with Smad3 and regulates Smad3-mediated TGF-beta signaling during oxidative stress responses.
|
| Li H, Sekine M, Seng S, Avraham S, Avraham HK.
|
| PLoS One. 4(9):e7091. 2009
|
| 106 | BRCA1
|
| Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells.
|
| Deng C, Ueda E, Chen KE, Bula C, Norman AW, Luben RA, Walker AM.
|
| Mol Endocrinol. 23(2):226-36. 2009
|
| 107 | BRCA1
|
| Dynamic interactions of proteins in complex networks: identifying the complete set of interacting E2s for functional investigation of E3-dependent protein ubiquitination.
|
| Christensen DE, Klevit RE.
|
| FEBS J. 276(19):5381-9. 2009
|
| 108 | BRCA1
|
| BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair.
|
| Adamo A, Montemauri P, Silva N, Ward JD, Boulton SJ, La Volpe A.
|
| EMBO Rep 9(3):287-92. Epub 2008 Jan 25.
2008
|
| 109 | APC, BRCA1, BRCA2, CDH1, CDKN2A, MLH1, MSH2, MSH6, PMS2, PRSS1, PTEN, RB1, SPINK1, STK11, TP53
|
| Inherited susceptibility to common cancers.
|
| Foulkes WD.
|
| N Engl J Med 359(20):2143-53. No abstract available.
2008
|
| 110 | ACACA, BRCA1
|
| Structural evidence for direct interactions between the BRCT domains of human BRCA1 and a phospho-peptide from human ACC1.
|
| Shen Y, Tong L.
|
| Biochemistry 47(21):5767-73. Epub 2008 May 2.PMID: 18452305 2008
|
| 111 | BRCA1
|
| BRCA1 transcriptional activity is enhanced by interactions between its AD1 domain and AhR.
|
| Kang HJ, Kim HJ, Cho CH, Hu Y, Li R, Bae I.
|
| Cancer Chemother Pharmacol. 62(6):965-75. 2008
|
| 112 | BRCA1
|
| Interaction of p14ARF with Brca1 in cancer cell lines and primary breast cancer.
|
| He L, Fan C, Ning X, Feng X, Liu Y, Chen B, Tang D.
|
| Cell Biol Int 32(10):1302-9. 2008
|
| 113 | BRCA1
|
| Gamma-irradiation-induced DNA damage checkpoint activation involves feedback regulation between extracellular signal-regulated kinase 1/2 and BRCA1.
|
| Yan Y, Black CP, Cao PT, Haferbier JL, Kolb RH, Spieker RS, Ristow AM, Cowan KH.
|
| Cancer Res. 68(13):5113-21. 2008
|
| 114 | BRCA1
|
| SUMO1 negatively regulates BRCA1-mediated transcription, via modulation of promoter occupancy.
|
| Park MA, Seok YJ, Jeong G, Lee JS.
|
| Nucleic Acids Res. 36(1):263-83. 2008
|
| 115 | BRCA1
|
| Rapid recruitment of BRCA1 to DNA double-strand breaks is dependent on its association with Ku80.
|
| Wei L, Lan L, Hong Z, Yasui A, Ishioka C, Chiba N.
|
| Mol Cell Biol. 28(24):7380-93. 2008
|
| 116 | BRCA1,BRCA2
|
| Cancer risks in carriers of the BRCA1/2 Ashkenazi founder mutations.
|
| Kadouri L, Hubert A, Rotenberg Y, Hamburger T, Sagi M, Nechushtan C, Abeliovich D, Peretz T.
|
| J Med Genet 44(7):467-71. Epub 2007 Feb 16. 2007
|
| 117 | BRCA1
|
| Compromised Fanconi anemia response due to BRCA1 deficiency in cisplatin-sensitive head and neck cancer cell lines.
|
| Burkitt K, Ljungman M.
|
| Cancer Lett 253(1):131-7. Epub 2007 Feb 26. 2007
|
| 118 | BRCA1, FAM175A, UIMC1
|
| Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response.
|
| Wang B, Matsuoka S, Ballif BA, Zhang D, Smogorzewska A, Gygi SP, Elledge SJ.
|
| Science 316(5828):1194-8. 2007
|
| 119 | BRCA1, FAM175A
|
| CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response.
|
| Kim H, Huang J, Chen J.
|
| Nat Struct Mol Biol 14(8):710-5. Epub 2007 Jul 22. 2007
|
| 120 | BRCA1, FAM175A, UIMC1
|
| CCDC98 targets BRCA1 to DNA damage sites.
|
| Liu Z, Wu J, Yu X.
|
| Nat Struct Mol Biol 14(8):716-20. Epub 2007 Jul 22. 2007
|
| 121 | BRCA1, ESR1, PGR, PYCARD
|
| Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients.
|
| Mirza S, Sharma G, Prasad CP, Parshad R, Srivastava A, Gupta SD, Ralhan R.
|
| Life Sci 81(4):280-7. Epub 2007 May 25. 2007
|
| 122 | BRCA1, BARD1
|
| Structural Requirements for the BARD1 Tumor Suppressor in Chromosomal Stability and Homology-directed DNA Repair.
|
| Laufer M, Nandula SV, Modi AP, Wang S, Jasin M, Murty VV, Ludwig T, Baer R.
|
| J Biol Chem 282(47):34325-33. Epub 2007 Sep 11. 2007
|
| 123 | BRCA1, PPP1CB
|
| The interaction of PP1 with BRCA1 and analysis of their expression in breast tumors.
|
| Winter SL, Bosnoyan-Collins L, Pinnaduwage D, Andrulis IL.
|
| BMC Cancer 7:85. 2007
|
| 124 | BARD1, BRCA1, BRCC3, FAM175A, RNF8, UIMC1
|
| Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
|
| Wang B, Elledge SJ.
|
| Proc Natl Acad Sci U S A 104(52):20759-63. Epub 2007 Dec 5. 2007
|
| 125 | BARD1, BRCA1, BRCC3, FAM175A, UIMC1
|
| Wang B, Elledge SJ.
|
| Ubc13/Rnf8 ubiquitin ligases control foci formation of the Rap80/Abraxas/Brca1/Brcc36 complex in response to DNA damage.
|
| Proc Natl Acad Sci U S A 104(52):20759-63. Epub 2007 Dec 5. 2007
|
| 126 | BRCA1
|
| Phosphorylation of ATR-interacting protein on Ser239 mediates an interaction with breast-ovarian cancer susceptibility 1 and checkpoint function.
|
| Venere M, Snyder A, Zgheib O, Halazonetis TD.
|
| Cancer Res. 67(13):6100-5. 2007
|
| 127 | ACACA, BRCA1
|
| BRCA1 affects lipid synthesis through its interaction with acetyl-CoA carboxylase.
|
| Moreau K, Dizin E, Ray H, Luquain C, Lefai E, Foufelle F, Billaud M, Lenoir GM, Venezia ND.
|
| J Biol Chem 281(6):3172-81. Epub 2005 Dec 2. 2006
|
| 128 | BRCA1
|
| Genetic, functional, and histopathological evaluation of two C-terminal BRCA1 missense variants.
|
| Lovelock PK, Healey S, Au W, Sum EY, Tesoriero A, Wong EM, Hinson S, Brinkworth R, Bekessy A, Diez O, Izatt L, Solomon E, Jenkins M, Renard H, Hopper J, Waring P, Tavtigian SV, Goldgar D, Lindeman GJ, Visvader JE, Couch FJ, Henderson BR, Southey M, Chenevix-Trench G, Spurdle AB, Brown MA; kConFab Investigators.
|
| J Med Genet 43(1):74-83. Epub 2005 May 27. 2006
|
| 129 | BRCA1, BARD1, UBE2D1
|
| Genetic analysis of BRCA1 ubiquitin ligase activity and its relationship to breast cancer susceptibility.
|
| Morris JR, Pangon L, Boutell C, Katagiri T, Keep NH, Solomon E.
|
| Hum Mol Genet 15(4):599-606. Epub 2006 Jan 10. 2006
|
| 130 | BRCA1, BRCA2, CSB, ELOA, ERCC6
|
| Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling.
|
| Newman JC, Bailey AD, Weiner AM.
|
| Proc Natl Acad Sci U S A 103(25):9613-8. Epub 2006 Jun 13. 2006
|
| 131 | BRCA1,CAV1
|
| Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells.
|
| Glait C, Ravid D, Lee SW, Liscovitch M, Werner H.
|
| FEBS Lett 580(22):5268-74. Epub 2006 Sep 11. 2006
|
| 132 | BACH1, BRCA1
|
| BACH1 is a DNA repair protein supporting BRCA1 damage response.
|
| Peng M, Litman R, Jin Z, Fong G, Cantor SB.
|
| Oncogene 25(15):2245-53. 2006
|
| 133 | BRCA1
|
| Mapping and conformational characterization of the DNA-binding region of the breast cancer susceptibility protein BRCA1.
|
| Naseem R, Sturdy A, Finch D, Jowitt T, Webb M.
|
| Biochem J 395(3):529-35. 2006
|
| 134 | BRCA1, BRCA2, DEPDC1B
|
| Chromosome 5 imbalance mapping in breast tumors from BRCA1 and BRCA2 mutation carriers and sporadic breast tumors.
|
| Johannsdottir HK, Jonsson G, Johannesdottir G, Agnarsson BA, Eerola H, Arason A, Heikkila P, Egilsson V, Olsson H, Johannsson OT, Nevanlinna H, Borg A, Barkardottir RB.
|
| Int J Cancer 119(5):1052-60.
2006
|
| 135 | BRCA1, RBBP8, ZNF350
|
| Removal of BRCA1/CtIP/ZBRK1 repressor complex on ANG1 promoter leads to accelerated mammary tumor growth contributed by prominent vasculature.
|
| Furuta S, Wang JM, Wei S, Jeng YM, Jiang X, Gu B, Chen PL, Lee EY, Lee WH.
|
| Cancer Cell 10(1):13-24.
2006
|
| 136 | BRCA1
|
| Prevention of Brca1-mediated mammary tumorigenesis in mice by a progesterone antagonist.
|
| Poole AJ, Li Y, Kim Y, Lin SC, Lee WH, Lee EY.
|
| Science. 314(5804):1467-70. 2006
|
| 137 | BRCA1
|
| An hGCN5/TRRAP histone acetyltransferase complex co-activates BRCA1 transactivation function through histone modification.
|
| Oishi H, Kitagawa H, Wada O, Takezawa S, Tora L, Kouzu-Fujita M, Takada I, Yano T, Yanagisawa J, Kato S.
|
| J Biol Chem. 281(1):20-6. 2006
|
| 138 | BRCA1
|
| BRCA1 modulates xenobiotic stress-inducible gene expression by interacting with ARNT in human breast cancer cells.
|
| Kang HJ, Kim HJ, Kim SK, Barouki R, Cho CH, Khanna KK, Rosen EM, Bae I.
|
| J Biol Chem. 281(21):14654-62. 2006
|
| 139 | BRCA1
|
| BRCA1 interacts with poly(A)-binding protein: implication of BRCA1 in translation regulation.
|
| Dizin E, Gressier C, Magnard C, Ray H, Décimo D, Ohlmann T, Dalla Venezia N.
|
| J Biol Chem. 281(34):24236-46. 2006
|
| 140 | BRCA1
|
| Identification of two evolutionarily conserved and functional regulatory elements in intron 2 of the human BRCA1 gene.
|
| Wardrop SL, Brown MA; kConFab Investigators.
|
| Genomics 86(3):316-28. 2005
|
| 141 | BRCA1, BRCA2
|
| Genetic testing in an ethnically diverse cohort of high-risk women: a comparative analysis of BRCA1 and BRCA2 mutations in American families of European and African ancestry.
|
| Nanda R, Schumm LP, Cummings S, Fackenthal JD, Sveen L, Ademuyiwa F, Cobleigh M, Esserman L, Lindor NM, Neuhausen SL, Olopade OI.
|
| JAMA 294(15):1925-33. 2005
|
| 142 | BRCA1
|
| TGFbeta1/Smad3 counteracts BRCA1-dependent repair of DNA damage.
|
| Dubrovska A, Kanamoto T, Lomnytska M, Heldin CH, Volodko N, Souchelnytskyi S.
|
| Oncogene. 24(14):2289-97. 2005
|
| 143 | BRCA1
|
| BRCA1 can modulate RNA polymerase II carboxy-terminal domain phosphorylation levels.
|
| Moisan A, Larochelle C, Guillemette B, Gaudreau L.
|
| Mol Cell Biol. 24(16):6947-56. 2004
|
| 144 | BRCA1, BARD1
|
| BRCA1 : BARD1 induces the formation of conjugated ubiquitin structures, dependent on K6 of ubiquitin, in cells during DNA replication and repair.
|
| Morris JR, Solomon E.
|
| Hum Mol Genet 13(8):807-17. Epub 2004 Feb 19. 2004
|
| 145 | BRCA1, CALML5, MRC1
|
| Human Claspin works with BRCA1 to both positively and negatively regulate cell proliferation.
|
| Lin SY, Li K, Stewart GS, Elledge SJ.
|
| Proc Natl Acad Sci U S A 101(17):6484-9. Epub 2004 Apr 19. 2004
|
| 146 | MCPH1, BRCA1
|
| Reconstructing the evolutionary history of microcephalin, a gene controlling human brain size.
|
| Evans PD, Anderson JR, Vallender EJ, Choi SS, Lahn BT.
|
| Hum Mol Genet 13(11):1139-45. Epub 2004 Mar 31. 2004
|
| 147 | MCPH1, BRCA1, CHEK1
|
| Microcephalin is a DNA damage response protein involved in regulation of CHK1 and BRCA1.
|
| Xu X, Lee J, Stern DF.
|
| J Biol Chem 279(33):34091-4. Epub 2004 Jun 25. 2004
|
| 148 | AURKA, BRCA1
|
| BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition.
|
| Ouchi M, Fujiuchi N, Sasai K, Katayama H, Minamishima YA, Ongusaha PP, Deng C, Sen S, Lee SW, Ouchi T.
|
| J Biol Chem. 279(19):19643-8 2004
|
| 149 | BRCA1
|
| Genetic interactions between Brca1 and Gadd45a in centrosome duplication, genetic stability, and neural tube closure.
|
| Wang X, Wang RH, Li W, Xu X, Hollander MC, Fornace AJ Jr, Deng CX.
|
| J Biol Chem. 279(28):29606-14. 2004
|
| 150 | BRCA1
|
| BRCA1 interacts with and is required for paclitaxel-induced activation of mitogen-activated protein kinase kinase kinase 3.
|
| Gilmore PM, McCabe N, Quinn JE, Kennedy RD, Gorski JJ, Andrews HN, McWilliams S, Carty M, Mullan PB, Duprex WP, Liu ET, Johnston PG, Harkin DP.
|
| Cancer Res. 64(12):4148-54. 2004
|
| 151 | BRCA1
|
| BRCA1 function mediates a TRAP/DRIP complex through direct interaction with TRAP220.
|
| Wada O, Oishi H, Takada I, Yanagisawa J, Yano T, Kato S.
|
| Oncogene. 23(35):6000-5. 2004
|
| 152 | BRCA1
|
| BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II.
|
| Cabart P, Chew HK, Murphy S.
|
| Oncogene. 23(31):5316-29. 2004
|
| 153 | BRCA1
|
| BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.
|
| Hill DA, de la Serna IL, Veal TM, Imbalzano AN.
|
| J Cell Biochem. 91(5):987-98. 2004
|
| 154 | BRCA1
|
| Nucleophosmin/B23 is a candidate substrate for the BRCA1-BARD1 ubiquitin ligase.
|
| Sato K, Hayami R, Wu W, Nishikawa T, Nishikawa H, Okuda Y, Ogata H, Fukuda M, Ohta T.
|
| J Biol Chem. 279(30):30919-22. 2004
|
| 155 | BRCA1
|
| Association of BRCA1 with the inactive X chromosome and XIST RNA.
|
| Ganesan S, Silver DP, Drapkin R, Greenberg R, Feunteun J, Livingston DM.
|
| Philos Trans R Soc Lond B Biol Sci. 359(1441):123-8. 2004
|
| 156 | BRCA1, TP53
|
| BRCA1: a scaffold for p53 response?
|
| Hohenstein P, Giles RH.
|
| Trends Genet 19(9):489-94. No abstract available. 2003
|
| 157 | BRCA1
|
| BRCT repeats as phosphopeptide-binding modules involved in protein targeting.
|
| Manke IA, Lowery DM, Nguyen A, Yaffe MB.
|
| Science 302(5645):636-9. 2003
|
| 158 | BRCA1
|
| The BRCT domain is a phospho-protein binding domain.
|
| Yu X, Chini CC, He M, Mer G, Chen J.
|
| Science 302(5645):639-42. 2003
|
| 159 | BRCA1, BARD1
|
| The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin.
|
| Wu-Baer F, Lagrazon K, Yuan W, Baer R.
|
| J Biol Chem 278(37):34743-6. Epub 2003 Jul 30. 2003
|
| 160 | BRCA1, BRCA2, BRCC3
|
| Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
|
| Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R.
|
| Mol Cell 12(5):1087-99. 2003
|
| 161 | BRCA1
|
| Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice.
|
| Xu X, Aprelikova O, Moens P, Deng CX, Furth PA.
|
| Development 130(9):2001-12.
2003
|
| 162 | BRCA1, BRCA2, BRE
|
| Regulation of BRCC, a holoenzyme complex containing BRCA1 and BRCA2, by a signalosome-like subunit and its role in DNA repair.
|
| Dong Y, Hakimi MA, Chen X, Kumaraswamy E, Cooch NS, Godwin AK, Shiekhattar R.
|
| Mol Cell 12(5):1087-99.
2003
|
| 163 | BRCA1
|
| A member of the Pyrin family, IFI16, is a novel BRCA1-associated protein involved in the p53-mediated apoptosis pathway.
|
| Aglipay JA, Lee SW, Okada S, Fujiuchi N, Ohtsuka T, Kwak JC, Wang Y, Johnstone RW, Deng C, Qin J, Ouchi T.
|
| Oncogene. 22(55):8931-8. 2003
|
| 164 | BRCA1, ETS2
|
| Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
|
| Baker KM, Wei G, Schaffner AE, Ostrowski MC.
|
| J Biol Chem. 278(20):17876-84. 2003
|
| 165 | BRCA1
|
| BRCA1-Sp1 interactions in transcriptional regulation of the IGF-IR gene.
|
| Abramovitch S, Glaser T, Ouchi T, Werner H.
|
| FEBS Lett. 541(1-3):149-54. 2003
|
| 166 | BRCA1
|
| BRCA1 interacts with FHL2 and enhances FHL2 transactivation function.
|
| Yan J, Zhu J, Zhong H, Lu Q, Huang C, Ye Q.
|
| FEBS Lett. 553(1-2):183-9. 2003
|
| 167 | BRCA1
|
| BRCA1 augments transcription by the NF-kappaB transcription factor by binding to the Rel domain of the p65/RelA subunit.
|
| Benezra M, Chevallier N, Morrison DJ, MacLachlan TK, El-Deiry WS, Licht JD.
|
| J Biol Chem. 278(29):26333-41. 2003
|
| 168 | BRCA1
|
| Functional and physical interactions between BRCA1 and p53 in transcriptional regulation of the IGF-IR gene.
|
| Abramovitch S, Werner H.
|
| Horm Metab Res. 35(11-12):758-62. 2003
|
| 169 | BRCA1
|
| Isolation and characterization of a BRCA1-interacting protein
|
| Yan JH, Ye QN, Zhu JH, Zhong HJ, Zheng HY, Huang CF.
|
| Yi Chuan Xue Bao 30(12):1161-6. 2003
|
| 170 | BRCA1
|
| BRCA1 associates with processive RNA polymerase II.
|
| Krum SA, Miranda GA, Lin C, Lane TF.
|
| J Biol Chem. 278(52):52012-20. 2003
|
| 171 | BRCA1, GADD45A, GADD45B, GADD45G, NFYA, POU2F1
|
| BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs.
|
| Fan W, Jin S, Tong T, Zhao H, Fan F, Antinore MJ, Rajasekaran B, Wu M, Zhan Q.
|
| J Biol Chem 277(10):8061-7. 2002
|
| 172 | BRCA1, LMO4, RBBP8
|
| The LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activity.
|
| Sum EY, Peng B, Yu X, Chen J, Byrne J, Lindeman GJ, Visvader JE.
|
| J Biol Chem 277(10):7849-56. 2002
|
| 173 | BRCA1, EP300, ESR1
|
| p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
|
| Fan S, Ma YX, Wang C, Yuan RQ, Meng Q, Wang JA, Erdos M, Goldberg ID, Webb P, Kushner PJ, Pestell RG, Rosen EM.
|
| Cancer Res 62(1):141-51. 2002
|
| 174 | BRCA1, CHEK1
|
| BRCA1 regulates the G2/M checkpoint by activating Chk1 kinase upon DNA damage.
|
| Yarden RI, Pardo-Reoyo S, Sgagias M, Cowan KH, Brody LC.
|
| Nat Genet 30(3):285-9. 2002
|
| 175 | BRCA1, CDKN1B
|
| BRCA1 transactivates the cyclin-dependent kinase inhibitor p27(Kip1).
|
| Williamson EA, Dadmanesh F, Koeffler HP.
|
| Oncogene 21(20):3199-206. 2002
|
| 176 | BARD1, BRCA1
|
| The BRCA1 and BARD1 association with the RNA polymerase II holoenzyme.
|
| Chiba N, Parvin JD.
|
| Cancer Res 62(15):4222-8. 2002
|
| 177 | BARD1, BRCA1
|
| BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export.
|
| Fabbro M, Rodriguez JA, Baer R, Henderson BR.
|
| J Biol Chem 277(24):21315-24. 2002
|
| 178 | BRCA1
|
| Structural determinants of BRCA1 translational regulation.
|
| Sobczak K, Krzyzosiak WJ.
|
| J Biol Chem 277(19):17349-58. 2002
|
| 179 | BRCA1, JUN, JUNB
|
| JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction.
|
| Hu YF, Li R.
|
| Genes Dev 16(12):1509-17. 2002
|
| 180 | BRCA1, FANCA
|
| BRCA1 interacts directly with the Fanconi anemia protein FANCA.
|
| Folias A, Matkovic M, Bruun D, Reid S, Hejna J, Grompe M, D'Andrea A, Moses R.
|
| Hum Mol Genet 11(21):2591-7. 2002
|
| 181 | BRCA1, BRCA2
|
| Hereditary breast and ovarian cancer in Asia: genetic epidemiology of BRCA1 and BRCA2.
|
| Liede A, Narod SA.
|
| Hum Mutat 20(6):413-24. Review. 2002
|
| 182 | BARD1, BRCA1
|
| The BRCA1/BARD1 heterodimer, a tumor suppressor complex with ubiquitin E3 ligase activity.
|
| Baer R, Ludwig T.
|
| Curr Opin Genet Dev 12(1):86-91. Review. 2002
|
| 183 | BRCA1
|
| Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1.
|
| Ekblad CM, Wilkinson HR, Schymkowitz JW, Rousseau F, Freund SM, Itzhaki LS.
|
| J Mol Biol 320(3):431-42. 2002
|
| 184 | FANCD2, BRCA1, RAD51
|
| S-phase-specific interaction of the Fanconi anemia protein, FANCD2, with BRCA1 and RAD51.
|
| Taniguchi T, Garcia-Higuera I, Andreassen PR, Gregory RC, Grompe M, D'Andrea AD.
|
| Blood 100(7):2414-20. 2002
|
| 185 | BRCA1, BRCA2
|
| Clinical characteristics of individuals with germline mutations in BRCA1 and BRCA2: analysis of 10,000 individuals.
|
| Frank TS, Deffenbaugh AM, Reid JE, Hulick M, Ward BE, Lingenfelter B, Gumpper KL, Scholl T, Tavtigian SV, Pruss DR, Critchfield GC.
|
| J Clin Oncol 20(6):1480-90. 2002
|
| 186 | ABL1, BRCA1
|
| Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.
|
| Foray N, Marot D, Randrianarison V, Venezia ND, Picard D, Perricaudet M, Favaudon V, Jeggo P.
|
| Mol Cell Biol. 22(12):4020-32. 2002
|
| 187 | BRCA1
|
| BRCA1 interacts with acetyl-CoA carboxylase through its tandem of BRCT domains.
|
| Magnard C, Bachelier R, Vincent A, Jaquinod M, Kieffer S, Lenoir GM, Venezia ND.
|
| Oncogene. 21(44):6729-39. 2002
|
| 188 | BRCA1
|
| A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer.
|
| Li H, Lee TH, Avraham H.
|
| J Biol Chem. 277(23):20965-73. 2002
|
| 189 | BRCA1
|
| Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells.
|
| Kawai H, Li H, Chun P, Avraham S, Avraham HK
|
| Oncogene. 21(50):7730-9. 2002
|
| 190 | BRCA1
|
| Regulation of BRCA1 phosphorylation by interaction with protein phosphatase 1alpha.
|
| Liu Y, Virshup DM, White RL, Hsu LC.
|
| Cancer Res. 62(22):6357-61. 2002
|
| 191 | BRCA1
|
| BRCA1 and BRCA2 bind Stat5a and suppress its transcriptional activity.
|
| Vidarsson H, Mikaelsdottir EK, Rafnar T, Bertwistle D, Ashworth A, Eyfjord JE, Valgeirsdottir S.
|
| FEBS Lett. 532(1-2):247-52. 2002
|
| 192 | BRCA1
|
| Subcellular localization of the BRCA1 gene product in mitotic cells.
|
| Lotti LV, Ottini L, D'Amico C, Gradini R, Cama A, Belleudi F, Frati L, Torrisi MR, Mariani-Costantini R.
|
| Genes Chromosomes Cancer. 35(3):193-203. 2002
|
| 193 | BRCA1
|
| Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity.
|
| Ruffner H, Joazeiro CA, Hemmati D, Hunter T, Verma IM.
|
| Proc Natl Acad Sci U S A 98(9):5134-9. 2001
|
| 194 | BRCA1
|
| Functional analysis of BRCA1 C-terminal missense mutations identified in breast and ovarian cancer families.
|
| Vallon-Christersson J, Cayanan C, Haraldsson K, Loman N, Bergthorsson JT, Brondum-Nielsen K, Gerdes AM, Moller P, Kristoffersson U, Olsson H, Borg A, Monteiro AN.
|
| Hum Mol Genet 10(4):353-60. 2001
|
| 195 | BACH1, BRCA1, BRIP1
|
| BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
|
| Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.
|
| Cell 105(1):149-60. 2001
|
| 196 | BRCA1, FANCD2
|
| Interaction of the Fanconi anemia proteins and BRCA1 in a common pathway.
|
| Garcia-Higuera I, Taniguchi T, Ganesan S, Meyn MS, Timmers C, Hejna J, Grompe M, D'Andrea AD.
|
| Mol Cell 7(2):249-62. 2001
|
| 197 | BRCA1
|
| Identification of a gamma-tubulin-binding domain in BRCA1.
|
| Hsu LC, Doan TP, White RL.
|
| Cancer Res. 61(21):7713-8. 2001
|
| 198 | BARD1, BRCA1
|
| The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation.
|
| Hashizume R, Fukuda M, Maeda I, Nishikawa H, Oyake D, Yabuki Y, Ogata H, Ohta T.
|
| J Biol Chem 276(18):14537-40. 2001
|
| 199 | BRCA1, BRCA2
|
| Prevalence and penetrance of germline BRCA1 and BRCA2 mutations in a population series of 649 women with ovarian cancer.
|
| Risch HA, McLaughlin JR, Cole DE, Rosen B, Bradley L, Kwan E, Jack E, Vesprini DJ, Kuperstein G, Abrahamson JL, Fan I, Wong B, Narod SA.
|
| Am J Hum Genet 68(3):700-10. Epub 2001 Feb 15. 2001
|
| 200 | BRCA1
|
| BRCA2 is required for homology-directed repair of chromosomal breaks
|
| Moynahan, M. E.; Pierce, A. J.; Jasin, M.
|
| Mol Cell. 7: 263-272 2001
|
| 201 | BRCA1, JAK2, STAT3
|
| Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells.
|
| Gao B, Shen X, Kunos G, Meng Q, Goldberg ID, Rosen EM, Fan S.
|
| FEBS Lett. 488(3):179-84. 2001
|
| 202 | BRCA1
|
| Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis.
|
| Xu X, Qiao W, Linke SP, Cao L, Li WM, Furth PA, Harris CC, Deng CX.
|
| Nat Genet. 28(3):266-71. 2001
|
| 203 | BRCA1
|
| c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells.
|
| Chai Y, Chipitsyna G, Cui J, Liao B, Liu S, Aysola K, Yezdani M, Reddy ES, Rao VN.
|
| Oncogene. 20(11):1357-67. 2001
|
| 204 | BRCA1
|
| Rb-associated protein 46 (RbAp46) inhibits transcriptional transactivation mediated by BRCA1.
|
| Chen GC, Guan LS, Yu JH, Li GC, Choi Kim HR, Wang ZY.
|
| Biochem Biophys Res Commun. 284(2):507-14. 2001
|
| 205 | BRCA1
|
| Comparison between genotype and phenotype identifies a high-risk population carrying BRCA1 mutations.
|
| Cortesi L, Turchetti D, Bertoni C, Bellei R, Mangone L, Vinceti M, Federico M, Silingardi V, Ferrari S.
|
| Genes Chromosomes Cancer 27(2):130-5 2000
|
| 206 | BRCA1, CREBBP, EP300
|
| CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
|
| Pao GM, Janknecht R, Ruffner H, Hunter T, Verma IM.
|
| Proc Natl Acad Sci U S A 97(3):1020-5. 2000
|
| 207 | BRCA1, BRCA2
|
| BRCA1 and BRCA2 mutation analysis of 208 Ashkenazi Jewish women with ovarian cancer.
|
| Moslehi R, Chu W, Karlan B, Fishman D, Risch H, Fields A, Smotkin D, Ben-David Y, Rosenblatt J, Russo D, Schwartz P, Tung N, Warner E, Rosen B, Friedman J, Brunet JS, Narod SA.
|
| Am J Hum Genet 66(4):1259-72. 2000
|
| 208 | BRCA1
|
| An alu-mediated 7.1 kb deletion of BRCA1 exons 8 and 9 in breast and ovarian cancer families that results in alternative splicing of exon 10.
|
| Rohlfs EM, Puget N, Graham ML, Weber BL, Garber JE, Skrzynia C, Halperin JL, Lenoir GM, Silverman LM, Mazoyer S.
|
| Genes Chromosomes Cancer 28(3):300-7. 2000
|
| 209 | BRCA1, BRCA2
|
| Multiple copies of mutant BRCA1 and BRCA2 alleles in breast tumors from germ-line mutation carriers.
|
| Staff S, Nupponen NN, Borg A, Isola JJ, Tanner MM.
|
| Genes Chromosomes Cancer 28(4):432-42. 2000
|
| 210 | BRCA1, IFNG, STAT1
|
| Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes.
|
| Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM.
|
| Proc Natl Acad Sci U S A 97(10):5208-13. 2000
|
| 211 | BRCA1, SMARCA4
|
| BRCA1 is associated with a human SWI/SNF-related complex: linking chromatin remodeling to breast cancer.
|
| Bochar DA, Wang L, Beniya H, Kinev A, Xue Y, Lane WS, Wang W, Kashanchi F, Shiekhattar R.
|
| Cell 102(2):257-65. 2000
|
| 212 | ATM, BRCA1
|
| Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response.
|
| Li S, Ting NS, Zheng L, Chen PL, Ziv Y, Shiloh Y, Lee EY, Lee WH.
|
| Nature 406(6792):210-5. 2000
|
| 213 | BRCA1
|
| The exon 13 duplication in the BRCA1 gene is a founder mutation present in geographically diverse populations. The BRCA1 Exon 13 Duplication Screening Group.
|
| [No authors listed] Related Articles, OMIM
|
| Am J Hum Genet 67(1):207-12. 2000
|
| 214 | BRCA1, BRIP1
|
| Abnormal expression of BRCA1 and BRCA1-interactive DNA-repair proteins in breast carcinomas.
|
| Yoshikawa K, Ogawa T, Baer R, Hemmi H, Honda K, Yamauchi A, Inamoto T, Ko K, Yazumi S, Motoda H, Kodama H, Noguchi S, Gazdar AF, Yamaoka Y, Takahashi R.
|
| Int J Cancer 88(1):28-36. 2000
|
| 215 | BRCA1, ZNF350
|
| Sequence-specific transcriptional corepressor function for BRCA1 through a novel zinc finger protein, ZBRK1.
|
| Zheng L, Pan H, Li S, Flesken-Nikitin A, Chen PL, Boyer TG, Lee WH.
|
| Mol Cell 6(4):757-68. 2000
|
| 216 | ATF1, BRCA1
|
| BRCA1 physically and functionally interacts with ATF1.
|
| Houvras Y, Benezra M, Zhang H, Manfredi JJ, Weber BL, Licht JD.
|
| J Biol Chem. 275(46):36230-7. 2000
|
| 217 | BRCA1, MSH2
|
| BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures.
|
| Wang Y, Cortez D, Yazdi P, Neff N, Elledge SJ, Qin J.
|
| Genes Dev. 14(8):927-39. 2000
|
| 218 | BRCA1
|
| Identification of a functional nuclear export sequence in BRCA1.
|
| Rodríguez JA, Henderson BR.
|
| J Biol Chem. 275(49):38589-96. 2000
|
| 219 | BRCA1
|
| Ataxia telangiectasia-related protein is involved in the phosphorylation of BRCA1 following deoxyribonucleic acid damage.
|
| Chen J.
|
| Cancer Res. 60(18):5037-9. 2000
|
| 220 | BRCA1
|
| Breast cancer susceptibility gene 1 (BRCAI) is a coactivator of the androgen receptor.
|
| Park JJ, Irvine RA, Buchanan G, Koh SS, Park JM, Tilley WD, Stallcup MR, Press MF, Coetzee GA.
|
| Cancer Res. 60(21):5946-9. 2000
|
| 221 | BRCA1
|
| Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress.
|
| Tibbetts RS, Cortez D, Brumbaugh KM, Scully R, Livingston D, Elledge SJ, Abraham RT
|
| Genes Dev. 14(23):2989-3002. 2000
|
| 222 | BRCA1
|
| BRCA1 interaction with RNA polymerase II reveals a role for hRPB2 and hRPB10alpha in activated transcription.
|
| Schlegel BP, Green VJ, Ladias JA, Parvin JD.
|
| Proc Natl Acad Sci U S A. 97(7):3148-53. 2000
|
| 223 | BRCA1
|
| VCP, a weak ATPase involved in multiple cellular events, interacts physically with BRCA1 in the nucleus of living cells.
|
| Zhang H, Wang Q, Kajino K, Greene MI.
|
| DNA Cell Biol. 19(5):253-63. 2000
|
| 224 | BRCA1
|
| Screening for germ-line rearrangements and regulatory mutations in BRCA1 led to the identification of four new deletions.
|
| Puget N, et al.
|
| Cancer Res 59(2):455-61. 1999
|
| 225 | BRCA1
|
| BRCA1 gene mutation and loss of heterozygosity on chromosome 17q21 in primary prostate cancer.
|
| Uchida T, et al.
|
| Int J Cancer 84(1):19-23. 1999
|
| 226 | BRCA1, RNU2@
|
| Evidence for effective suppression of recombination in the chromosome 17q21 segment spanning RNU2-BRCA1.
|
| Liu X, et al.
|
| Am J Hum Genet 64(5):1427-39. 1999
|
| 227 | BRCA1
|
| Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1.
|
| Harkin DP, et al.
|
| Cell 97(5):575-86. 1999
|
| 228 | BRCA1
|
| BRCA1 IVS16+6T-->C is a deleterious mutation that creates an aberrant transcript by activating a cryptic splice donor site.
|
| Scholl T, et al.
|
| Am J Med Genet 85(2):113-6. 1999
|
| 229 | BRCA1
|
| BRCA1 mutations in familial ovarian cancer.
|
| Lallas TA, et al.
|
| Mol Genet Metab 67(4):357-63. 1999
|
| 230 | BRCA1
|
| Identification of a 3 kb Alu-mediated BRCA1 gene rearrangement in two breast/ovarian cancer families.
|
| Montagna M, et al.
|
| Oncogene 18(28):4160-5 1999
|
| 231 | BRCA1, RB1
|
| BRCA1-associated growth arrest is RB-dependent.
|
| Aprelikova ON, et al.
|
| Proc Natl Acad Sci U S A 96(21):11866-71 1999
|
| 232 | BRCA1, HDAC1, HDAC2
|
| BRCA1 interacts with components of the histone deacetylase complex.
|
| Yarden RI, et al.
|
| Proc Natl Acad Sci U S A 96(9):4983-8 1999
|
| 233 | BRCA1, BRCA2
|
| The Contribution of Germline BRCA1 and BRCA2 Mutations to Familial Ovarian Cancer: No Evidence for Other Ovarian Cancer-Susceptibility Genes.
|
| Gayther SA, et al.
|
| Am J Hum Genet 65(4):1021-1029 1999
|
| 234 | BRCA1, BRCA2, RAD51, RAD54L
|
| Detection of loss of heterozygosity at RAD51, RAD52, RAD54 and BRCA1 and BRCA2 loci in breast cancer: pathological correlations.
|
| Gonzalez R, Silva JM, Dominguez G, Garcia JM, Martinez G, Vargas J, Provencio M, Espana P, Bonilla F.
|
| Br J Cancer 81(3):503-9 1999
|
| 235 | BRCA1, MKRN1, MKRN2, MKRN3, MKRNP1, MKRNP2, MKRNP3, MKRNP4, MKRNP5, MKRNP6, RNF139, SIAH1, SIAH2
|
| RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination.
|
| Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM.
|
| Proc Natl Acad Sci U S A 96(20):11364-9 1999
|
| 236 | ATM, BRCA1
|
| Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks.
|
| Cortez D, Wang Y, Qin J, Elledge SJ.
|
| Science 286(5442):1162-6 1999
|
| 237 | BRCA1
|
| Brca1 controls homology-directed DNA repair.
|
| Moynahan ME, Chiu JW, Koller BH, Jasin M.
|
| Mol Cell. 4(4):511-8. 1999
|
| 238 | BRCA1
|
| BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site.
|
| Ruffner H, Jiang W, Craig AG, Hunter T, Verma IM.
|
| Mol Cell Biol. 19(7):4843-54. 1999
|
| 239 | BRCA1
|
| Casein kinase 2 binds to and phosphorylates BRCA1.
|
| O'Brien KA, Lemke SJ, Cocke KS, Rao RN, Beckmann RP.
|
| Biochem Biophys Res Commun. 260(3):658-64. 1999
|
| 240 | BRCA1, FAS, RAD50
|
| Association of BRCA1 with the hRad50-hMre11-p95 complex and the DNA damage response.
|
| Zhong Q, Chen CF, Li S, Chen Y, Wang CC, Xiao J, Chen PL, Sharp ZD, Lee WH.
|
| Science. 285(5428):747-50. 1999
|
| 241 | BRCA1
|
| The second BRCT domain of BRCA1 proteins interacts with p53 and stimulates transcription from the p21WAF1/CIP1 promoter.
|
| Chai YL, Cui J, Shao N, Shyam E, Reddy P, Rao VN.
|
| Oncogene. 18(1):263-8. 1999
|
| 242 | BRCA1
|
| Heregulin induces phosphorylation of BRCA1 through phosphatidylinositol 3-Kinase/AKT in breast cancer cells.
|
| Altiok S, Batt D, Altiok N, Papautsky A, Downward J, Roberts TM, Avraham H.
|
| J Biol Chem. 274(45):32274-8. 1999
|
| 243 | BRCA1
|
| Binding of CtIP to the BRCT repeats of BRCA1 involved in the transcription regulation of p21 is disrupted upon DNA damage.
|
| Li S, Chen PL, Subramanian T, Chinnadurai G, Tomlinson G, Osborne CK, Sharp ZD, Lee WH.
|
| J Biol Chem. 274(16):11334-8. 1999
|
| 244 | BRCA1, BRCA2
|
| Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families.
|
| Ford D, et al.
|
| Am J Hum Genet 62 : 676-689. 1998
|
| 245 | BRCA1, TSG17B
|
| Frequent microsatellite instability and loss of heterozygosity in the region including BRCA1 (17q21) in young patients with gastric cancer.
|
| Semba S, et al.
|
| Int J Oncol 12 : 1245-1251. 1998
|
| 246 | BRCA1
|
| BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A.
|
| Anderson SF, et al.
|
| Nat Genet 19 : 254-256. 1998
|
| 247 | BRCA1
|
| BRCA1-related breast cancer in Austrian breast and ovarian cancer families : specific BRCA1 mutations and pathological characteristics.
|
| Wagner TM, et al.
|
| Int J Cancer 77 : 354-360. 1998
|
| 248 | BRCA1
|
| A high proportion of mutations in the BRCA1 gene in German breast/ovarian cancer families with clustering of mutations in the 3' third of the gene.
|
| Dong J, et al.
|
| Hum Genet 103 : 154-161. 1998
|
| 249 | BRCA1
|
| New mechanism of BRCA-1 mutation by deletion/insertion at the same nucleotide position in three unrelated French breast/ovarian cancer families.
|
| Presneau N, et al.
|
| Hum Genet 103 : 334-339. 1998
|
| 250 | APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
|
| Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
|
| Hooper ML.
|
| EMBO J 17(23):6783-9. 1998
|
| 251 | BRCA1, BRCA2
|
| Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families.
|
| Tonin PN, Mes-Masson AM, Futreal PA, Morgan K, Mahon M, Foulkes WD, Cole DE, Provencher D, Ghadirian P, Narod SA.
|
| Am J Hum Genet 63 : 1341-1351. 1998
|
| 252 | BRCA1, CBS, MTHFR, MTR, NTDS1, T
|
| Susceptibility to spina bifida : an association study of five candidate genes.
|
| Morrison K, et al.
|
| Ann Hum Genet 62 : 379-396. 1998
|
| 253 | BRCA1
|
| BRCA1 is associated with the centrosome during mitosis.
|
| Hsu LC, et al.
|
| Proc Natl Acad Sci U S A 95(22):12983-8. 1998
|
| 254 | BRCA1, RBBP8
|
| Characterization of a carboxy-terminal BRCA1 interacting protein.
|
| Wong AK, Ormonde PA, Pero R, Chen Y, Lian L, Salada G, Berry S, Lawrence Q, Dayananth P, Ha P, Tavtigian SV, Teng DH, Bartel PL.
|
| Oncogene 17(18):2279-85. 1998
|
| 255 | BRCA1, BRCA2
|
| Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells.
|
| Chen, J.; Silver, D. P.; Walpita, D.; Cantor, S. B.; Gazdar, A. F.; Tomlinson, G.; Couch, F. J.; Weber, B. L.; Ashley, T.; Livingston, D. M.; Scully, R.
|
| Mol Cell. 2: 317-328 1998
|
| 256 | BRCA1, MYC
|
| BRCA1 binds c-Myc and inhibits its transcriptional and transforming activity in cells.
|
| Wang Q, Zhang H, Kajino K, Greene MI.
|
| Oncogene. 17(15):1939-48 1998
|
| 257 | BRCA1
|
| BRCA1 physically associates with p53 and stimulates its transcriptional activity.
|
| Zhang H, Somasundaram K, Peng Y, Tian H, Zhang H, Bi D, Weber BL, El-Deiry WS.
|
| Oncogene. 16(13):1713-21. 1998
|
| 258 | BRCA1
|
| BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
|
| Jensen DE, Proctor M, Marquis ST, Gardner HP, Ha SI, Chodosh LA, Ishov AM, Tommerup N, Vissing H, Sekido Y, Minna J, Borodovsky A, Schultz DC, Wilkinson KD, Maul GG, Barlev N, Berger SL, Prendergast GC, Rauscher FJ 3rd.
|
| Oncogene. 16(9):1097-112. 1998
|
| 259 | BRCA1
|
| Identification of a novel cytoplasmic protein that specifically binds to nuclear localization signal motifs.
|
| Li S, Ku CY, Farmer AA, Cong YS, Chen CF, Lee WH.
|
| J Biol Chem. 273(11):6183-9. 1998
|
| 260 | BRCA1
|
| The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression.
|
| Yu X, Wu LC, Bowcock AM, Aronheim A, Baer R.
|
| J Biol Chem. 273(39):25388-92. 1998
|
| 261 | BRCA1, BRCA2
|
| A breast/ovarian cancer patient with germline mutations in both BRCA1 and BRCA2.
|
| Ramus SJ, et al.
|
| Nat Genet 15 : 14-15. 1997
|
| 262 | BRCA1
|
| Localization of BRCA1 and a splice variant identifies the nuclear localization signal.
|
| Thakur S, et al.
|
| Mol Cell Biol 17 : 444-452. 1997
|
| 263 | BRCA1, RAD51
|
| Association of BRCA1 with Rad51 in mitotic and meiotic cells.
|
| Scully R, et al.
|
| Cell 88 : 265-275. 1997
|
| 264 | BRCA1
|
| New nonsense mutation in the breast cancer-1 gene in a French site-specific breast cancer family.
|
| Laplace-Marieze V, et al.
|
| Hum Mutat 9 : 474. 1997
|
| 265 | BRCA1
|
| BRCA1 sequence variations in 160 individuals referred to a breast/ovarian family cancer clinic.
|
| Stoppa-Lyonnet D, et al.
|
| Am J Hum Genet 60 : 1021-1030. 1997
|
| 266 | BRCA1
|
| BRCA1 is a component of the RNA polymerase II holoenzyme.
|
| Scully R, Anderson SF, Chao DM, Wei W, Ye L, Young RA, Livingston DM, Parvin JD.
|
| Proc Natl Acad Sci U S A 94(11):5605-10. 1997
|
| 267 | BRCA1
|
| Mutational analysis of BRCA1 gene in ovarian and breast-ovarian cancer families in Japan.
|
| Takano M, Aida H, Tsuneki I, Takakuwa K, Hasegawa I, Tanaka H, Saito M, Tsuji S, Sonoda T, Hatae M, Chen JT, Takahashi K, Hasegawa K, Toyoda N, Saito N, Yakushiji M, Araki T, Tanaka K.
|
| Jpn J Cancer Res 88(4):407-13. 1997
|
| 268 | BRCA1, NBR1, NBR2
|
| Isolation and characterisation of the NBR2 gene which lies head to head with the human BRCA1 gene.
|
| Xu CF, Brown MA, Nicolai H, Chambers JA, Griffiths BL, Solomon E.
|
| Hum Mol Genet 6(7):1057-62. 1997
|
| 269 | BRCA1
|
| BRCA1 is a cell cycle-regulated nuclear phosphoprotein.
|
| Ruffner H, Verma IM.
|
| Proc Natl Acad Sci U S A 94(14):7138-43. 1997
|
| 270 | BRCA1
|
| The 12 base pair duplication/insertion alteration could be a regulatory mutation.
|
| Robledo M, Osorio A, Sentis C, Albertos J, Estevez L, Benitez J.
|
| J Med Genet 34(7):592-3. 1997
|
| 271 | BRCA1
|
| Identification of a 14 kb deletion involving the promoter region of BRCA1 in a breast cancer family.
|
| Swensen J, Hoffman M, Skolnick MH, Neuhausen SL.
|
| Hum Mol Genet 6(9):1513-7. 1997
|
| 272 | BRCA1
|
| BRCA1 genomic deletions are major founder mutations in Dutch breast cancer patients.
|
| Petrij-Bosch A, Peelen T, van Vliet M, van Eijk R, Olmer R, Drusedau M, Hogervorst FB, Hageman S, Arts PJ, Ligtenberg MJ, Meijers-Heijboer H, Klijn JG, Vasen HF, Cornelisse CJ, van 't Veer LJ, Bakker E, van Ommen GJ, Devilee P.
|
| Nat Genet 17(3):341-5. Erratum in: Nat Genet 1997 Dec;17(4):503. 1997
|
| 273 | BRCA1
|
| From BRCA1 to RAP1 : a widespread BRCT module closely associated with DNA repair.
|
| Callebaut I, et al.
|
| FEBS Lett 400 : 25-30. 1997
|
| 274 | BRCA1, DNTT, ECT2, MDM4, RAD9A, XPC, XRCC1
|
| From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair.
|
| Callebaut I, et al.
|
| FEBS Lett 400(1):25-30. 1997
|
| 275 | BRCA1, DNTT, ECT2, MDM4, RAD9A, XRCC1
|
| A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
|
| Bork P, et al.
|
| FASEB J 11(1):68-76. 1997
|
| 276 | BRCA1, BRCA2
|
| The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women.
|
| Abeliovich D, Kaduri L, Lerer I, Weinberg N, Amir G, Sagi M, Zlotogora J, Heching N, Peretz T.
|
| Am J Hum Genet 60(3):505-14. 1997
|
| 277 | BRCA1, CDK5, E2F1
|
| BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases.
|
| Wang H, Shao N, Ding QM, Cui J, Reddy ES, Rao VN.
|
| Oncogene. 15(2):143-57. 1997
|
| 278 | BRCA1
|
| Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.
|
| Ludwig T, Chapman DL, Papaioannou VE, Efstratiadis A.
|
| Genes Dev. 11(10):1226-41. 1997
|
| 279 | BRCA1, TSG17B
|
| BRCA1 mutations in a population-based sample of young women with breast cancer.
|
| Langston AA, et al.
|
| N Engl J Med 334 : 137-142. 1996
|
| 280 | BRCA1, TSG17B
|
| A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families.
|
| Serova O, et al.
|
| Am J Hum Genet 58 : 42-51. 1996
|
| 281 | BRCA1
|
| Haplotype and phenotype analysis of six recurrent BRCA1 mutations in 61 families : results of an international study.
|
| Neuhausen SL, et al.
|
| Am J Hum Genet 58 : 271-280. 1996
|
| 282 | TSG17B, BRCA1
|
| Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities.
|
| Gowen LC, et al.
|
| Nat Genet 12 : 191-194. 1996
|
| 283 | BRCA1, D17S1185, D17S1186, D17S1187, D17S1332, D17S1333, D17S1334, D17S1335, D17S1336, D17S1337, D17S1338, D17S1339, D17S1340, D17S1341, D17S1342, D17S1343
|
| Isolation of tetranucleotide repeat polymorphisms flanking the BRCA1 gene.
|
| Bennett-Baker PE, et al.
|
| Genomics 32 : 163-167. 1996
|
| 284 | BRCA1
|
| Rapid detection of regionally clustered germ-line BRCA1 mutations by multiplex heteroduplex analysis.
|
| Gayther SA, et al.
|
| Am J Hum Genet 58 : 451-456. 1996
|
| 285 | BRCA1
|
| Founding BRCA1 mutations in hereditary breast and ovarian cancer in Southern Sweden.
|
| Johannsson O, et al.
|
| Am J Hum Genet 58 : 441-450. 1996
|
| 286 | BRCA1
|
| BRCA1 is secreted and exhibits properties of a granin.
|
| Jensen RA, et al.
|
| Nat Genet 12 : 303-308. 1996
|
| 287 | BRCA1
|
| Granin expectations in breast cancer ?
|
| Steeg PS.
|
| Nat Genet 12 : 223-225. 1996
|
| 288 | BRCA1, BRCA2
|
| Hereditary breast cancer. Pathobiology, prognosis, and BRCA1 and BRCA2 gene linkage.
|
| Marcus JN, et al.
|
| Cancer 77 : 697-709. 1996
|
| 289 | BRCA1
|
| Comparison of BRCA1 polymorphisms, rare sequence variants and/or missense mutations in unaffected and breast/ovarian cancer populations.
|
| Durocher F, et al.
|
| Hum Mol Genet 5 : 835-842. 1996
|
| 290 | BRCA1
|
| Two distinct origins of a common BRCA1 mutation in breast-ovarian cancer families : a genetic study of 15 185delAG-mutation kindreds.
|
| Berman DB, et al.
|
| Am J Hum Genet 58 : 1166-1176. 1996
|
| 291 | BRCA1
|
| Mutations and polymorphisms in the familial early-onset breast cancer (BRCA1) gene.
|
| Couch FJ, et al.
|
| Hum Mutat 8 : 8-18. 1996
|
| 292 | BRCA1
|
| Mutations in the BRCA1 gene in Japanese breast cancer patients.
|
| Katagiri T, et al.
|
| Hum Mutat 7 : 334-339. 1996
|
| 293 | BRCA1
|
| Human, canine and murine BRCA1 genes : sequence comparison among species.
|
| Szabo CI, et al.
|
| Hum Mol Genet 5 : 1289-1298. 1996
|
| 294 | BRCA1
|
| BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner.
|
| Chen Y, et al.
|
| Cancer Res 56 : 3168-3172. 1996
|
| 295 | BRCA1, TSG17B
|
| BRCA1 mutations in a selected series of breast/ovarian cancer patients.
|
| Garvin AM, et al.
|
| J Med Genet 33 : 721-725. 1996
|
| 296 | BRCA1, BRCA2
|
| Genetic heterogeneity in hereditary breast cancer : role of BRCA1 and BRCA2.
|
| Rebbeck TR, et al.
|
| Am J Hum Genet 59 : 547-553. 1996
|
| 297 | BRCA1, BRCA1P1, NBR1, NBR2
|
| The 5' end of the BRCA1 gene lies within a duplicated region of human chromosome 17q21.
|
| Brown MA, Xu CF, Nicolai H, Griffiths B, Chambers JA, Black D, Solomon E.
|
| Oncogene 12 : 2507-2513. 1996
|
| 298 | BRCA1
|
| Mutation analysis of the BRCA1 gene in 23 families with cases of cancer of the breast, ovary, and multiple other sites.
|
| Durocher F, et al.
|
| J Med Genet 33 : 814-819. 1996
|
| 299 | BRCA1
|
| Clinical and pathological features of ovarian cancer in women with germ-line mutations of BRCA1.
|
| Rubin SC, et al.
|
| N Engl J Med 335 : 1413-1416. 1996
|
| 300 | BRCA1
|
| A novel mutation in the BRCA1 gene in a German early-onset breast cancer family.
|
| Waindzoch B, et al.
|
| Hum Mutat 8 : 393. 1996
|
| 301 | NBR1, NBR2, BRCA1, BRCA1P1
|
| The BRCA1 and 1A1.3B promoters are parallel elements of a genomic duplication at 17q21.
|
| Barker DF, et al.
|
| Genomics 38 : 215-222. 1996
|
| 302 | BRCA1
|
| Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis.
|
| Hacia JG, et al.
|
| Nat Genet 14 : 441-447. 1996
|
| 303 | BRCA1, IFI35, RND2, RPL21L, AOC3P
|
| Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.
|
| Smith TM, et al.
|
| Genome Res 6 : 1029-1049. 1996
|
| 304 | BRCA1
|
| The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.
|
| Hakem R, de la Pompa JL, Sirard C, Mo R, Woo M, Hakem A, Wakeham A, Potter J, Reitmair A, Billia F, Firpo E, Hui CC, Roberts J, Rossant J, Mak TW.
|
| Cell. 85(7):1009-23. 1996
|
| 305 | BRCA1
|
| The nuclear localization sequences of the BRCA1 protein interact with the importin-alpha subunit of the nuclear transport signal receptor.
|
| Chen CF, Li S, Chen Y, Chen PL, Sharp ZD, Lee WH.
|
| J Biol Chem. 271(51):32863-8. 1996
|
| 306 | BRCA1, HSD17B1, NRXN3, TUBG1, ATP6V0A1, PSME3
|
| Molecular cloning and expression pattern of genes from a 470 Kb region near BRCA1 locus on chromosome 17q21.
|
| Jacob ANK, et al.
|
| Oncogene 11 : 981-986. 1995
|
| 307 | TSG17B, BRCA1
|
| Localization of potential tumor suppressor loci to a < 2Mb region on chromosome 17q in human prostate cancer.
|
| Gao X, et al.
|
| Oncogene 11 : 1241-1247. 1995
|
| 308 | BRCA1
|
| A common BRCA1 mutation in the Ashkenazim.
|
| Goldgar DE, et al.
|
| Nat Genet 11 : 113-114. 1995
|
| 309 | BRCA1
|
| The carrier frequency of the BRCA1 185delAG mutation is approximately 1 percent in Ashkenazi Jewish individuals.
|
| Struewing JP, et al.
|
| Nat Genet 11 : 198-200. 1995
|
| 310 | BRCA1
|
| Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families.
|
| Friedman LS, et al.
|
| Am J Hum Genet 57 : 1284-1297. 1995
|
| 311 | BRCA1
|
| Distinct transcription start sites generate two forms of BRCA1 mRNA.
|
| Xu CF, et al.
|
| Hum Mol Genet 4 : 2259-2264. 1995
|
| 312 | BRCA1
|
| Germline mutations of the BRCA1 gene in breast and ovarian cancer families provide evidence for a genotype-phenotype correlation.
|
| Gayther SA, et al.
|
| Nat Genet 11 : 428-433. 1995
|
| 313 | BRCA1
|
| A human BRCA1 gene knockout.
|
| Boyd M, et al.
|
| Nature 375 : 541-542. 1995
|
| 314 | AOC3P,BRCA1,ETV4,EZH1,GSD1A,HSD17B2,NBR1
|
| Direct selection of expressed sequences within a 1-Mb region flanking BRCA1 on human chromosome 17q21.
|
| Osborne-Lawrence S, et al.
|
| Genomics 25 : 248-255. 1995
|
| 315 | AOC3P,ATP6V0A1,BRCA1,DDX5,ETV4,EZH1,FLT4R,GSD1A,HMG17P1,HSD17B1,NRXN3,RPL27,TUBG1
|
| Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17.
|
| Brody LC, et al.
|
| Genomics 25 : 238-247. 1995
|
| 316 | BRCA1
|
| A YAC-, P1-, and cosmid-based physical map of the BRCA1 region on chromosome 17q21.
|
| Couch FJ, et al.
|
| Genomics 25 : 264-273. 1995
|
| 317 | NBR1, BRCA1, EZH1, HERVK, HMG17P1, PSME3, NAGLU, DUSP3, RAB5C, TUBG1, AOC3P, ATP6V0A1, VAT1
|
| 22 genes from chromosome 17q21: cloning, sequencing, and characterization of mutations in breast cancer families and tumors.
|
| Friedman LS, Ostermeyer EA, Lynch ED, Welcsh P, Szabo CI, Meza JE, Anderson LA, Dowd P, Lee MK, Rowell SE, et al.
|
| Genomics 25(1):256-63. 1995
|
| 318 | BRCA1, TSG17B
|
| Loss of heterozygosity of the BRCA1 and other loci on chromosome 17q in human prostate cancer.
|
| Gao X, et al.
|
| Cancer Res 55 : 1002-1005. 1995
|
| 319 | BRCA1, TSG17B
|
| Somatic mutations in the BRCA1 gene in sporadic ovarian tumours.
|
| Merajver SD, et al.
|
| Nat Genet 9 : 439-443. 1995
|
| 320 | BRCA1, TSG17B
|
| Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression.
|
| Thompson ME, et al.
|
| Nat Genet 9 : 444-450. 1995
|
| 321 | BRCA1
|
| Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1.
|
| Brown MA, et al.
|
| Proc Natl Acad Sci U S A 92 : 4362-4366. 1995
|
| 322 | BRCA1
|
| Detection of eight BRCA1 mutations in 10 breast/ovarian cancer families, including 1 family with male breast cancer.
|
| Struewing JP, et al.
|
| Am J Hum Genet 57 : 1-7. 1995
|
| 323 | BRCA1
|
| An evaluation of genetic heterogeneity in 145 breast-ovarian cancer families.
|
| Narod SA, et al.
|
| Am J Hum Genet 56 : 254-264. 1995
|
| 324 | BRCA1
|
| Breast and ovarian cancer incidence in BRCAI-mutation carriers.
|
| Easton DF, et al.
|
| Am J Hum Genet 56 : 265-271. 1995
|
| 325 | BRCA1, VAT1
|
| Comparison of the positional cloning methods used to isolate the BRCA1 gene.
|
| Harshman K, Bell R, Rosenthal J, Katcher H, Miki Y, Swenson J, Gholami Z,Frye C, Ding W, Dayananth P, et al.
|
| Hum Mol Genet 4(8):1259-66. 1995
|
| 326 | BRCA1, HAPOD, HSD17B1
|
| Human familial and sporadic breast cancer : analysis of the coding regions of the 17beta-hydroxysteroid dehydrogenase 2 gene (EDH17B2) using a single-strand conformation polymorphism assay.
|
| Mannermaa A, et al.
|
| Hum Genet 93 : 319-324. 1994
|
| 327 | TSG17B, BRCA1
|
| Detection of allelic losses on 17q12-q21 chromosomal region in benign lesions and malignant tumors occurring in a familial context.
|
| Lalle P, et al.
|
| Oncogene 9 : 437-442. 1994
|
| 328 | BRCA1
|
| Genetic mapping of the BRCA1 region on chromosome 17q21.
|
| Albertsen H, et al.
|
| Am J Hum Genet 54 : 516-525. 1994
|
| 329 | BRCA1
|
| A radiation hybrid map of the BRCAI region.
|
| O'Connell P, et al.
|
| Am J Hum Genet 54 : 526-534. 1994
|
| 330 | BRCA1
|
| Localisation of the breast-ovarian cancer susceptibility gene (BRCAI) on 17q12-21 to an interval of < IcM.
|
| Smith SA, et al.
|
| Genes Chromosomes Cancer 10 : 71-76. 1994
|
| 331 | BRCA1
|
| Familial male breast cancer is not linked to the BRCA1 locus on chromosome 17q.
|
| Stratton MR, et al.
|
| Nat Genet 7 : 103-107. 1994
|
| 332 | BRCA1
|
| Loss of heterozygosity studies in tumors from families with breast-ovarian cancer syndrome.
|
| Zelada-Hedman M, et al.
|
| Hum Genet 94 : 231-234. 1994
|
| 333 | ACLY, BRCA1, CNP, KAT2A, NBR1, PSME3, PYY, RAB5C
|
| A physical map and candidate genes in the BRCA1 region on chromosome 17q12-21.
|
| Albertsen HM, et al.
|
| Nat Genet 7 : 472-479. 1994
|
| 334 | BRCA1, HAPOD, HSD17B1
|
| A point mutation in the putative TATA box, detected in nondiseased individuals and patients with hereditary breast cancer, decreases promoter activity of the 17beta-hydroxysteroid dehydrogenase type 1 gene 2 (EDH17B2) in vitro.
|
| Peltoketo H, et al.
|
| Genomics 23 : 250-252. 1994
|
| 335 | BRCA1
|
| A large kindred with 17q-linked breast and ovarian cancer : genetic, phenotypic, and genealogical analysis.
|
| Goldgar DE, et al.
|
| J Natl Cancer Inst 86 : 200-209. 1994
|
| 336 | TSG17B, BRCA1
|
| Detailed deletion mapping of chromosome segment 17q12-21 in sporadic breast tumours.
|
| Nagai MA, et al.
|
| Genes Chromosomes Cancer 11 : 58-62. 1994
|
| 337 | BRCA1
|
| The gene for hereditary breast-ovarian cancer, BRCA1, maps distal to EDH17B2 in chromosome region 17q12-q21.
|
| Tonin P, et al.
|
| Hum Mol Genet 3 : 1679-1682. 1994
|
| 338 | BRCA1
|
| Mutations in the BRCA1 gene in families with early-onset breast and ovarian cancer.
|
| Castilla LH, et al.
|
| Nat Genet 8 : 387-391. 1994
|
| 339 | BRCA1
|
| Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families.
|
| Simard J, et al.
|
| Nat Genet 8 : 392-398. 1994
|
| 340 | BRCA1
|
| Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families.
|
| Friedman LS, et al.
|
| Nat Genet 8 : 399-404. 1994
|
| 341 | BRCA1, ARL4D, 8EG2, BCC7, BCC8, BCC10, BCL1, ET6B, HERVK, MEOX1, DUSP3
|
| The detailed characterisation of a 400 kb cosmid walk in the BRCA1 region: identification and localisation of 10 genes including a dual-specificity phosphatase.
|
| Jones KA, Black DM, Brown MA, Griffiths BL, Nicolai HM, Chambers JA, Bonjardim M, Xu CF, Boyd M, McFarlane R, et al.
|
| Hum Mol Genet 3(11):1927-34. 1994
|
| 342 | BRCA1
|
| Familial site-specific ovarian cancer is linked to BRCAI on 17q12-21.
|
| Steichen-Gersdorf E, et al.
|
| Am J Hum Genet 55 : 870-875. 1994
|
| 343 | BRCA1, MEOX1
|
| Isolation of a diverged homeobox gene, MOX1, from the BRCA1 region on 17q21 by solution hybrid capture.
|
| Futreal PA, et al.
|
| Hum Mol Genet 3 : 1359-1364. 1994
|
| 344 | D17S1320, D17S1321, D17S1322, D17S1323, D17S1324, D17S1325, D17S1326, D17S1329, BRCA1
|
| A P1-based physical map of the region from D17S776 to D17S78 containing the breast cancer susceptibility gene BRCA1.
|
| Neuhausen SL, et al.
|
| Hum Mol Genet 3 : 1919-1926. 1994
|
| 345 | BRCA1
|
| BRCA1 mutations in primary breast and ovarian carcinomas.
|
| Futreal AP, et al.
|
| Science 266 : 120-122. 1994
|
| 346 | NBR1, BRCA1
|
| Regulation of BRCA1.
|
| Brown MA, et al.
|
| Nature 372 : 733. 1994
|
| 347 | BRCA1, VAT1
|
| A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.
|
| Miki Y, Swensen J, Shattuck-Eidens D, Futreal PA, Harshman K, TavtigianS, Liu Q, Cochran C, Bennett LM, Ding W, et al.
|
| Science 266(5182):66-71. 1994
|
| 348 | BRCA1, D17S74
|
| A linkage analysis of D17S74 (CMM86) in thirty-five families with premenopausal bilateral breast cancer.
|
| Haile RW, et al.
|
| Cancer Res 53 : 212-214. 1993
|
| 349 | BRCA1
|
| Genetic analysis of the BRCA1 region in a large breast/ovarian family : refinement of the minimal region containing BRCA1.
|
| Kelsell DP, et al.
|
| Hum Mol Genet 2 : 1823-1828. 1993
|
| 350 | BRCA1
|
| Genetic linkage analysis in familial breast and ovarian cancer : results from 214 families.
|
| Easton DF, et al.
|
| Am J Hum Genet 52 : 678-701. 1993
|
| 351 | BRCA1
|
| A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCAI).
|
| Black DM, et al.
|
| Am J Hum Genet 52 : 702-710. 1993
|
| 352 | BRCA1
|
| Linkage analysis of chromosome 17q markers and breast-ovarian cancer in Icelandic families, and possible relationship to prostatic cancer.
|
| Arason A, et al.
|
| Am J Hum Genet 52 : 711-717. 1993
|
| 353 | BRCA1, THRA, D17S183
|
| THRA1 and D17S183 flank an interval of <4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.
|
| Bowcock AM, et al.
|
| Am J Hum Genet 52 : 718-722. 1993
|
| 354 | BRCA1
|
| Linkage of a major breast cancer gene to chromosome 17q12-21 : results from 15 Edinburgh families.
|
| Cohen BB, et al.
|
| Am J Hum Genet 52 : 723-729. 1993
|
| 355 | BRCA1
|
| Linkage to markers for the chromosome region 17q12-q21 in 13 Dutch breast cancer kindreds.
|
| Devilee P, et al.
|
| Am J Hum Genet 52 : 730-735. 1993
|
| 356 | BRCA1
|
| A breast-ovarian cancer susceptibility gene maps to chromosome 17q21.
|
| Feunteun J, et al.
|
| Am J Hum Genet 52 : 736-742. 1993
|
| 357 | BRCA1
|
| Linkage analysis with markers on 17q in 29 Swedish breast cancer families.
|
| Lindblom A, et al.
|
| Am J Hum Genet 52 : 749-753. 1993
|
| 358 | BRCA1
|
| Chromosome 17q linkage studies of 18 Utah breast cancer kindreds.
|
| Goldgar DE, et al.
|
| Am J Hum Genet 52 : 743-748. 1993
|
| 359 | BRCA1
|
| Linkage analysis of 19 French breast cancer families, with five chromosome 17q markers.
|
| Mazoyer S, et al.
|
| Am J Hum Genet 52 : 754-760. 1993
|
| 360 | BRCA1
|
| Linkage studies with 17q and 18q markers in a breast/ovarian cancer family.
|
| Milner BJ, et al.
|
| Am J Hum Genet 52 : 761-766. 1993
|
| 361 | BRCA1
|
| Genetic heterogeneity and localization of a familial breast-ovarian cancer gene on chromosome 17q12-q21.
|
| Smith SA, et al.
|
| Am J Hum Genet 52 : 767-776. 1993
|
| 362 | BRCA1
|
| Linkage analysis of early-onset breast and ovarian cancer families, with markers on the long arm of chromosome 17.
|
| Spurr NK, et al.
|
| Am J Hum Genet 52 : 777-785. 1993
|
| 363 | BRCA1
|
| A linkage study in seven breast cancer families.
|
| Teare MD, et al.
|
| Am J Hum Genet 52 : 786-788. 1993
|
| 364 | BRCA1
|
| Linkage analysis in German breast cancer families with early onset of the disease, using highly polymorphic markers from the chromosome 17q11-q24 region.
|
| Zimmermann W, et al.
|
| Am J Hum Genet 52 : 789-791. 1993
|
| 365 | BRCA1, D17S409
|
| BRCA1 maps proximal to D17S579 on chromosome 17q21 by genetic analysis.
|
| Chamberlain JS, et al.
|
| Am J Hum Genet 52 : 792-798. 1993
|
| 366 | BRCA1, HSD17B1
|
| Genetic mapping of the breast-ovarian cancer syndrome to a small interval on chromosome 17q12-21 : exclusion of candidate genes EDH17B2 and RARA.
|
| Simard J, et al.
|
| Hum Mol Genet 2 : 1193-1199. 1993
|
| 367 | BRCA1
|
| High-density genetic map of the BRCA1 region of chromosome 17q12-q21.
|
| Anderson LA, et al.
|
| Genomics 17 : 618-623. 1993
|
| 368 | BRCA1
|
| A radiation hybrid map of the BRCA1 region of chromosome 17q12-q21.
|
| Abel KJ, et al.
|
| Genomics 17 : 632-641. 1993
|
| 369 | BRCA1
|
| Multicolor FISH mapping with Alu-PCR-amplified YAC clone DNA determines the order of markers in the BRCA1 region on chromosome 17q12-q21.
|
| Flejter WL, et al.
|
| Genomics 17 : 624-631. 1993
|
| 370 | BRCA1
|
| Linkage of familial breast cancer to chromosome 17q21 may not be restricted to early-onset disease.
|
| Margaritte P, et al.
|
| Am J Hum Genet 50 : 1231-1234. 1992
|
| 371 | BRCA1
|
| Genetic heterogeneity of early-onset familial breast cancer.
|
| Sobol H, et al.
|
| Hum Genet 89 : 381-383. 1992
|
| 372 | BRCA1
|
| Closing in on a breast cancer gene on chromosome 17q.
|
| Hall JM, et al.
|
| Am J Hum Genet 50 : 1235-1242. 1992
|
| 373 | BRCA1
|
| Genetic counselling and hereditary breast/ovarian cancer.
|
| Lynch HT, et al.
|
| Lancet 339 : 1181. 1991
|
| 374 | BRCA1
|
| Familial breast-ovarian cancer locus on chromosome 17q12-q23.
|
| Narod SA, et al.
|
| Lancet 338 : 82-83. 1991
|
| 375 | TSG17B, BRCA1
|
| Linkage of early-onset familial breast cancer to chromosome 17q21.
|
| Hall JM, et al.
|
| Science 250 : 1684-1689. 1990
|
| 376 | BRCA1
|
| Inheritance of proliferative breast disease in breast cancer kindreds.
|
| Skolnick MH, et al.
|
| Science 250 : 1715-1720. 1990
|
| 377 | BRCA1
|
| BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II.
|
| Cabart P, Chew HK, Murphy S.
|
|
|