Citations for
1BNIP3L
BNIP3L/NIX-mediated mitophagy protects against ischemic brain injury independent of PARK2.
Yuan Y, Zheng Y, Zhang X, Chen Y, Wu X, Wu J, Shen Z, Jiang L, Wang L, Yang W, Luo J, Qin Z, Hu W, Chen Z.
Autophagy utophagy. 2017 Aug 18:1-13. doi: 10.1080/15548627.2017.1357792. [Epub ahead of print] 2017
2BNIP3L
BNIP3L/NIX-dependent mitophagy regulates cell differentiation via metabolic reprogramming.
Esteban-Martínez L, Boya P.
Autophagy utophagy. 2017 Jun 14:0. doi: 10.1080/15548627.2017.1332567. [Epub ahead of print] 2017
3BNIP3L
Programmed mitophagy is essential for the glycolytic switch during cell differentiation.
Esteban-Martínez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Mariño G, Seco E, Durand S, Enot D, Graña O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P.
EMBO J 36(12):1688-1706. doi: 10.15252/embj.201695916. Epub 2017 May 2. 2017
4BNIP3, BNIP3L, FUNDC1, PINK1
Selective removal of mitochondria via mitophagy: distinct pathways for different mitochondrial stresses.
Wei H, Liu L, Chen Q.
Biochim Biophys Acta 1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1. Review. 2015
5BNIP3, BNIP3L
Mitochondrial autophagy: Origins, significance, and role of BNIP3 and NIX.
Ney PA.
Biochim Biophys Acta 1853(10 Pt B):2775-83. doi: 10.1016/j.bbamcr.2015.02.022. Epub 2015 Mar 6. Review. 2015
6BNIP3L, PRKN
The mitochondrial protein BNIP3L is the substrate of PARK2 and mediates mitophagy in PINK1/PARK2 pathway.
Gao F, Chen D, Si J, Hu Q, Qin Z, Fang M, Wang G.
Hum Mol Genet 24(9):2528-38. doi: 10.1093/hmg/ddv017. Epub 2015 Jan 22. 2015
7BNIP3, BNIP3L
BNIP3- and BNIP3L-Mediated Mitophagy Promotes the Generation of Natural Killer Cell Memory.
O'Sullivan TE, Johnson LR, Kang HH, Sun JC.
Immunity 43(2):331-42. doi: 10.1016/j.immuni.2015.07.012. Epub 2015 Aug 4. 2015
8BNIP3L
The stress-related hormone norepinephrine induced upregulation of Nix, contributing to ECM protein expression.
Liu W, Wang X, Gong J, Mei Z, Gao X, Zhao Y, Ma J, Qian L.
Cell Stress Chaperones 19(6):903-12. doi: 10.1007/s12192-014-0515-6. Epub 2014 May 7. 2014
9BNIP3, BNIP3L, C14orf1, CLN8, GABARAPL2, STX8, VAPA
Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis.
Passantino R, Cascio C, Deidda I, Galizzi G, Russo D, Spedale G, Guarneri P.
Biochim Biophys Acta 1833(3):529-40. doi: 10.1016/j.bbamcr.2012.10.030. Epub 2012 Nov 8. 2013
10BNIP3, BNIP3L
A nucleus-targeted alternately spliced Nix/Bnip3L protein isoform modifies nuclear factor κB (NFκB)-mediated cardiac transcription.
Chen Y, Decker KF, Zheng D, Matkovich SJ, Jia L, Dorn GW 2nd.
J Biol Chem 288(22):15455-65. doi: 10.1074/jbc.M113.452342. Epub 2013 Apr 19. 2013
11BNIP3, BNIP3L, SPATA18
BNIP3 and NIX mediate Mieap-induced accumulation of lysosomal proteins within mitochondria.
Nakamura Y, Kitamura N, Shinogi D, Yoshida M, Goda O, Murai R, Kamino H, Arakawa H.
PLoS One 7(1):e30767. doi: 10.1371/journal.pone.0030767. Epub 2012 Jan 26. 2012
12BNIP3L
A short linear motif in BNIP3L (NIX) mediates mitochondrial clearance in reticulocytes.
Zhang J, Loyd MR, Randall MS, Waddell MB, Kriwacki RW, Ney PA.
Autophagy 8(9):1325-32. doi: 10.4161/auto.20764. Epub 2012 Aug 21. 2012
13BNIP3L, CALR, CLTC, GABARAP, NBR1, SQSTM1
Atg8-family interacting motif crucial for selective autophagy.
Noda NN, Ohsumi Y, Inagaki F.
FEBS Lett 584(7):1379-85. Epub 2010 Jan 17. Review.PMID: 20083108 2010
14BNIP3L, PRKN
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming.
Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB, Dorn GW 2nd, Yin XM.
J Biol Chem 285(36):27879-90. doi: 10.1074/jbc.M110.119537. Epub 2010 Jun 23. 2010
15BNIP3, BNIP3L
Role of BNIP3 and NIX in cell death, autophagy, and mitophagy.
Zhang J, Ney PA.
Cell Death Differ 16(7):939-46. Epub 2009 Feb 20. 2009
16BNIP3, BNIP3L
Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains.
Bellot G, Garcia-Medina R, Gounon P, Chiche J, Roux D, Pouysségur J, Mazure NM.
Mol Cell Biol 29(10):2570-81. Epub 2009 Mar 9. 2009
17BNIP3L, GABARAP
Nix directly binds to GABARAP: a possible crosstalk between apoptosis and autophagy.
Schwarten M, Mohrlüder J, Ma P, Stoldt M, Thielmann Y, Stangler T, Hersch N, Hoffmann B, Merkel R, Willbold D.
Autophagy 5(5):690-8. Epub 2009 Jul 20.PMID: 19363302 2009
18IGFBP7, BNIP3L, SMARCB1
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.
Wajapeyee N, Serra RW, Zhu X, Mahalingam M, Green MR.
Cell 132(3):363-74. 2008
19BNIP3L
Essential role for Nix in autophagic maturation of erythroid cells.
Sandoval H, Thiagarajan P, Dasgupta SK, Schumacher A, Prchal JT, Chen M, Wang J.
Nature 454(7201):232-5. Epub 2008 May 4. 2008
20BNIP3, BNIP3L
BNIP3 subfamily BH3-only proteins: mitochondrial stress sensors in normal and pathological functions.
Chinnadurai G, Vijayalingam S, Gibson SB.
Oncogene 27 Suppl 1:S114-27. 2008
21BNIP3L
NIX is required for programmed mitochondrial clearance during reticulocyte maturation.
Schweers RL, Zhang J, Randall MS, Loyd MR, Li W, Dorsey FC, Kundu M, Opferman JT, Cleveland JL, Miller JL, Ney PA.
Proc Natl Acad Sci U S A 104(49):19500-5. Epub 2007 Nov 29. 2007
22ABL2, AKAP8, ANKRD13D, AP3D1, ARFGAP3, ARMCX6, ASUN, BAT2L, BCl2L13, BNIP3L, BPTF, BRD7, BZW1, BZW2, C12orf43, C19orf26, C1orf105, C2orf49, C6orf81, CA10, CAD, CARHSP1, CBX4, CCDC55, CCDC61, CCNK, CDC42BPB, CDC42EP3, CDC42EP4, CDS2, CENPN, CLK1, COPA, CSDA, CTPS2, DBN1, DCP1A, DECR2, DPF2, DPM1, EIF2AK1, EPB41L4A, EPN1, FAM91A1, FOSL2, FOXK1, GDF5OS, GFOD2, GIGYF2, GPATCH8, GTPBP1, HES7, HNRNPUL1, KIF1C, LPIN2, LRCH4, MAN2C1, MAST1, MED13, MED24, MED26, MINK1, MISP, MYO10, NKTR, OSBP, PAM, PCDH7, PEX14, PHF16, PHRF1, PLCB4, PLXNC1, POM121, POM121L2, PPHLN1, PRICKLE3, PRX, PUM2, RABGGTB, RBEL1, RIMS1, RIMS2, RPL14, RRP1B, RRP8, SAFB, SCAMP3, SCMH1, SCYL1, SENP6, SERBP1, SFRS13A, SFRS17A, SIPA1L1, SLC26A6, SLIRP, SLMAP, SNTA1, SORBS3, SPICE1, SSFA2, STAM, SUB1, TFIP11, TLN2, TMC6, TMEM104, TMEM106B, TMEM22, TOM1, UHRF1, UTP14A, WDR43, ZNF324, ZNF648
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M.
Cell. 127(3):635-48. 2006
23BNIP3L
The proapoptotic factor Nix is coexpressed with Bcl-xL during terminal erythroid differentiation.
Aerbajinai W, Giattina M, Lee YT, Raffeld M, Miller JL.
Blood 102(2):712-7. Epub 2003 Mar 27. 2003
24STEAP1, PKMYT1, BNIP3L, STEAP3
The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase.
Passer BJ, Nancy-Portebois V, Amzallag N, Prieur S, Cans C, Roborel de Climens A, Fiucci G, Bouvard V, Tuynder M, Susini L, Morchoisne S, Crible V, Lespagnol A, Dausset J, Oren M, Amson R, Telerman A.
Proc Natl Acad Sci U S A 100(5):2284-9. Epub 2003 Feb 26. 2003
25BNIP3L
BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3.
Yasuda M, et al.
Cancer Res 59(3):533-7. 1999
26BCL2, BNIP3L
Bcl-2/E1B 19 kDa-interacting protein 3-like protein (Bnip3L) interacts with bcl-2/Bcl-xL and induces apoptosis by altering mitochondrial membrane permeability.
Imazu T, Shimizu S, Tagami S, Matsushima M, Nakamura Y, Miki T, Okuyama A, Tsujimoto Y.
Oncogene 18(32):4523-9 1999
27BNIP3, BNIP3L
Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins.
Chen G, Cizeau J, Vande Velde C, Park JH, Bozek G, Bolton J, Shi L, Dubik D, Greenberg A.
J Biol Chem 274(1):7-10. 1999
28BAK1, BAX, BCL2, BCL2L2, BID, BNIP3L
The Bcl-2 protein family : arbiters of cell survival.
Adams JM, et al.
Science 281 : 1322-1326. 1998
29BNIP3L
Isolation, mapping, and functional analysis of a novel human cDNA (BNIP3L) encoding a protein homologous to human NIP3.
Matsushima M, Fujiwara T, Takahashi E, Minaguchi T, Eguchi Y, Tsujimoto Y, Suzumori K, Nakamura Y.
Genes Chromosomes Cancer 21(3):230-5. 1998
30BNIP3L, BNIP1, BNIP2
Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins.
Boyd JM, Malstrom S, Subramanian T, Venkatesh LK, Schaeper U, Elangovan B, D'Sa-Eipper C, Chinnadurai G.
Cell 79(2):341-51. 1994