| 1 | BMP4, TBX3
|
| Tbx3 represses bmp4 expression and with Pax6 is required and sufficient for retina formation.
|
| Motahari Z, Martinez-De Luna RI, Viczian AS, Zuber ME.
|
| Development evelopment. 2016 Aug 30. pii: dev.130955. [Epub ahead of print]
2016
|
| 2 | BMP4, RBM39, SIN3B
|
| Negative autoregulation of BMP dependent transcription by SIN3B splicing reveals a role for RBM39.
|
| Faherty N, Benson M, Sharma E, Lee A, Howarth A, Lockstone H, Ebner D, Bhattacharya S.
|
| Sci Rep 6:28210. doi: 10.1038/srep28210.
2016
|
| 3 | BMP4, MSX1, OSR2
|
| Bmp4-Msx1 signaling and Osr2 control tooth organogenesis through antagonistic regulation of secreted Wnt antagonists
|
| Jia S, Kwon HE, Lan Y, Zhou J, Liu H, Jiang R.
|
| Dev Biol. Dec 1;420(1):110-119. doi: 10.1016/j.ydbio.2016.10.001. Epub 2016 Oct 3 2016
|
| 4 | BMP4
|
| BMP4 promotes human Sertoli cell proliferation via Smad1/5 and ID2/3 pathway and its abnormality is associated with azoospermia.
|
| Hai Y, Sun M, Niu M, Yuan Q, Guo Y, Li Z, He Z.
|
| Discov Med 19(105):311-25.
2015
|
| 5 | ARSB, BMP4, CHST11, WNT9A
|
| Regulation of chondroitin-4-sulfotransferase (CHST11) expression by opposing effects of arylsulfatase B on BMP4 and Wnt9A.
|
| Bhattacharyya S, Feferman L, Tobacman JK.
|
| Biochim Biophys Acta 1849(3):342-52. doi: 10.1016/j.bbagrm.2014.12.009. Epub 2014 Dec 12.
2015
|
| 6 | BMP4, BMP7
|
| BMP4 and BMP7 induce the white-to-brown transition of primary human adipose stem cells.
|
| Elsen M, Raschke S, Tennagels N, Schwahn U, Jelenik T, Roden M, Romacho T, Eckel J.
|
| Am J Physiol Cell Physiol 306(5):C431-40. doi: 10.1152/ajpcell.00290.2013. Epub 2013 Nov 27.
2014
|
| 7 | BMP4
|
| Bone morphogenetic protein 4 inhibits liposaccharide-induced inflammation in the airway.
|
| Li Z, Wang J, Wang Y, Jiang H, Xu X, Zhang C, Li D, Xu C, Zhang K, Qi Y, Gong X, Tang C, Zhong N, Lu W.
|
| Eur J Immunol 44(11):3283-94. doi: 10.1002/eji.201344287. Epub 2014 Sep 25.
2014
|
| 8 | BMP4
|
| Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect.
|
| He F, Hu X, Xiong W, Li L, Lin L, Shen B, Yang L, Gu S, Zhang Y, Chen Y.
|
| Dev Biol 391(2):170-81. doi: 10.1016/j.ydbio.2014.04.013. Epub 2014 Apr 28.
2014
|
| 9 | BMP4
|
| Expression of bone morphogenetic protein 4 and its receptors in the remodeling heart.
|
| Wu X, Sagave J, Rutkovskiy A, Haugen F, Baysa A, Nygĺrd S, Czibik G, Dahl CP, Gullestad L, Vaage J, Valen G.
|
| Life Sci 97(2):145-54. doi: 10.1016/j.lfs.2013.12.030. Epub 2014 Jan 4.
2014
|
| 10 | BGLAP, BMP4
|
| Rho-kinase limits BMP-4-stimulated osteocalcin synthesis in osteoblasts: regulation of the p38 MAP kinase pathway.
|
| Kondo A, Tokuda H, Matsushima-Nishiwaki R, Kuroyanagi G, Yamamoto N, Mizutani J, Kozawa O, Otsuka T.
|
| Life Sci 96(1-2):18-25. doi: 10.1016/j.lfs.2013.12.017. Epub 2013 Dec 22.
2014
|
| 11 | BMP4
|
| Study of the association between the BMP4 gene and congenital anomalies of the kidney and urinary tract.
|
| Reis GS, Simőes E Silva AC, Freitas IS, Heilbuth TR, Marco LA, Oliveira EA, Miranda DM.
|
| J Pediatr (Rio J) 90(1):58-64. doi: 10.1016/j.jped.2013.06.004. Epub 2013 Oct 13.
2014
|
| 12 | BMP4, EDN3, MITF
|
| BMP4 is required for the initial expression of MITF in melanocyte precursor differentiation from embryonic stem cells.
|
| Yang J, Wang J, Pan L, Li H, Rao C, Zhang X, Niu G, Qu J, Hou L.
|
| Exp Cell Res 320(1):54-61. doi: 10.1016/j.yexcr.2013.09.017. Epub 2013 Sep 27.
2014
|
| 13 | BMP4
|
| BMP4/Thrombospondin-1 loop paracrinically inhibits tumor angiogenesis and suppresses the growth of solid tumors.
|
| Tsuchida R, Osawa T, Wang F, Nishii R, Das B, Tsuchida S, Muramatsu M, Takahashi T, Inoue T, Wada Y, Minami T, Yuasa Y, Shibuya M.
|
| Oncogene 33(29):3803-11. doi: 10.1038/onc.2013.358. Epub 2013 Sep 9.
2014
|
| 14 | BMP4, NOG
|
| Noggin attenuates the osteogenic activation of human valve interstitial cells in aortic valve sclerosis.
|
| Poggio P, Sainger R, Branchetti E, Grau JB, Lai EK, Gorman RC, Sacks MS, Parolari A, Bavaria JE, Ferrari G.
|
| Cardiovasc Res 98(3):402-10. doi: 10.1093/cvr/cvt055. Epub 2013 Mar 12.
2013
|
| 15 | BMP4, LIN28A
|
| Lin28 regulates BMP4 and functions with Oct4 to affect ovarian tumor microenvironment.
|
| Ma W, Ma J, Xu J, Qiao C, Branscum A, Cardenas A, Baron AT, Schwartz P, Maihle NJ, Huang Y.
|
| Cell Cycle 12(1):88-97. doi: 10.4161/cc.23028. Epub 2012 Dec 19.
2013
|
| 16 | BMP4, WISP2, ZNF423
|
| WISP2 regulates preadipocyte commitment and PPARγ activation by BMP4.
|
| Hammarstedt A, Hedjazifar S, Jenndahl L, Gogg S, Grünberg J, Gustafson B, Klimcakova E, Stich V, Langin D, Laakso M, Smith U.
|
| Proc Natl Acad Sci U S A 110(7):2563-8. doi: 10.1073/pnas.1211255110. Epub 2013 Jan 28.
2013
|
| 17 | BMP4
|
| BMP4 promotes vascularization of human adipose stromal cells and endothelial cells in vitro and in vivo.
|
| Zhou C, Cai X, Grottkau BE, Lin Y.
|
| Cell Prolif 46(6):695-704. doi: 10.1111/cpr.12073.
2013
|
| 18 | BMP4
|
| Bmp4 expressed in preadipocytes is required for the onset of adipocyte differentiation.
|
| Suenaga M, Kurosawa N, Asano H, Kanamori Y, Umemoto T, Yoshida H, Murakami M, Kawachi H, Matsui T, Funaba M.
|
| Cytokine 64(1):138-45. doi: 10.1016/j.cyto.2013.07.011. Epub 2013 Aug 2.
2013
|
| 19 | BMP4, PTK2
|
| The role of focal adhesion kinase in BMP4 induction of mesenchymal stem cell adipogenesis.
|
| Lee JS, Ha L, Kwon IK, Lim JY.
|
| Biochem Biophys Res Commun 435(4):696-701. doi: 10.1016/j.bbrc.2013.05.045. Epub 2013 May 20.
2013
|
| 20 | BMP4, WWTR1
|
| BMP4 is a novel transcriptional target and mediator of mammary cell migration downstream of the Hippo pathway component TAZ.
|
| Lai D, Yang X.
|
| Cell Signal 25(8):1720-8. doi: 10.1016/j.cellsig.2013.05.002. Epub 2013 May 11.
2013
|
| 21 | BMP4
|
| Identification of the control region of pancreatic expression of Bmp4 in vitro and in vivo.
|
| Yasunaga M, Masui E, Oji A, Soma A, Osaki M, Nakanishi T, Sato K.
|
| PLoS One 8(4):e61821. doi: 10.1371/journal.pone.0061821. Print 2013.
2013
|
| 22 | BMP4, DKK2, MSX1, OSR2
|
| Roles of Bmp4 during tooth morphogenesis and sequential tooth formation.
|
| Jia S, Zhou J, Gao Y, Baek JA, Martin JF, Lan Y, Jiang R.
|
| Development 140(2):423-32. doi: 10.1242/dev.081927.
2013
|
| 23 | BMP4, EBF2, EBF3
|
| Bmp4 regulates chick Ebf2 and Ebf3 gene expression in somite development.
|
| El-Magd MA, Allen S, McGonnell I, Otto A, Patel K.
|
| Dev Growth Differ 55(8):710-22. doi: 10.1111/dgd.12077.
2013
|
| 24 | BMP4, MSX1, TBX2
|
| Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development
|
| Saadi I, Das P, Zhao M, Raj L, Ruspita I, Xia Y, Papaioannou VE, Bei M
|
| Development. Jul;140(13):2697-702. doi: 10.1242/dev.088393. Epub 2013 May 29 2013
|
| 25 | BMP4, DEL14Q22
|
| Variability in expression of a familial 2.79 Mb microdeletion in chromosome14q22.1-22.2.
|
| Lumaka A, Van Hole C, Casteels I, Ortibus E, De Wolf V, Vermeesch JR, Lukusa T, Devriendt K.
|
| Am J Med Genet A 158A(6):1381-7. doi: 10.1002/ajmg.a.35353. Epub 2012 May 11.
2012
|
| 26 | BMP4, JUND
|
| The role of heterodimeric AP-1 protein comprised of JunD and c-Fos proteins in hematopoiesis.
|
| Lee SY, Yoon J, Lee MH, Jung SK, Kim DJ, Bode AM, Kim J, Dong Z.
|
| J Biol Chem 287(37):31342-8. doi: 10.1074/jbc.M112.387266. Epub 2012 Jul 20.
2012
|
| 27 | BMP2, BMP4
|
| Expression of BMP-2 and BMP-4 proteins by type-1 and type-2 astrocytes induced from neural stem cells under different differentiation conditions.
|
| Hu JG, Zhang YX, Qi Q, Wang R, Shen L, Zhang C, Xi J, Zhou JS, Lu HZ.
|
| Acta Neurobiol Exp (Wars) 72(1):95-101.
2012
|
| 28 | BMP4
|
| BMP4 is a novel paracrine inhibitor of liver regeneration.
|
| Do N, Zhao R, Ray K, Ho K, Dib M, Ren X, Kuzontkoski P, Terwilliger E, Karp SJ.
|
| Am J Physiol Gastrointest Liver Physiol 303(11):G1220-7. doi: 10.1152/ajpgi.00105.2012. Epub 2012 Sep 27.
2012
|
| 29 | BMP4
|
| Evaluation of germline BMP4 mutation as a cause of colorectal cancer.
|
| Lubbe SJ, Pittman AM, Matijssen C, Twiss P, Olver B, Lloyd A, Qureshi M, Brown N, Nye E, Stamp G, Blagg J, Houlston RS.
|
| Hum Mutat 32(1):E1928-38. doi: 10.1002/humu.21376. Epub 2010 Oct 14.
2011
|
| 30 | BMP4, SMAD1, WIF1
|
| Smad1 and its target gene Wif1 coordinate BMP and Wnt signaling activities to regulate fetal lung development.
|
| Xu B, Chen C, Chen H, Zheng SG, Bringas P Jr, Xu M, Zhou X, Chen D, Umans L, Zwijsen A, Shi W.
|
| Development 138(5):925-35. Epub 2011 Jan 26.
2011
|
| 31 | BMP2, BMP4, NEO1
|
| Neogenin, a receptor for bone morphogenetic proteins.
|
| Hagihara M, Endo M, Hata K, Higuchi C, Takaoka K, Yoshikawa H, Yamashita T.
|
| J Biol Chem 286(7):5157-65. Epub 2010 Dec 13.
2011
|
| 32 | BMP4
|
| Activation of bone morphogenetic protein 4 signaling leads to glomerulosclerosis that mimics diabetic nephropathy.
|
| Tominaga T, Abe H, Ueda O, Goto C, Nakahara K, Murakami T, Matsubara T, Mima A, Nagai K, Araoka T, Kishi S, Fukushima N, Jishage K, Doi T.
|
| J Biol Chem 286(22):20109-16. Epub 2011 Apr 6.
2011
|
| 33 | BMP4
|
| BMP4 promotes prostate tumor growth in bone through osteogenesis.
|
| Lee YC, Cheng CJ, Bilen MA, Lu JF, Satcher RL, Yu-Lee LY, Gallick GE, Maity SN, Lin SH.
|
| Cancer Res 71(15):5194-203. Epub 2011 Jun 13.
2011
|
| 34 | BMP4
|
| BMP4 loss-of-function mutations in developmental eye disorders including SHORT syndrome.
|
| Reis LM, Tyler RC, Schilter KF, Abdul-Rahman O, Innis JW, Kozel BA, Schneider AS, Bardakjian TM, Lose EJ, Martin DM, Broeckel U, Semina EV.
|
| Hum Genet 130(4):495-504. doi: 10.1007/s00439-011-0968-y. Epub 2011 Feb 22.
2011
|
| 35 | BMP4, TBX1
|
| Inactivation of Bmp4 from the Tbx1 expression domain causes abnormal pharyngeal arch artery and cardiac outflow tract remodeling.
|
| Nie X, Brown CB, Wang Q, Jiao K.
|
| Cells Tissues Organs 193(6):393-403. doi: 10.1159/000321170. Epub 2010 Dec 1.
2011
|
| 36 | BMP2, BMP4, DPYSL2
|
| The suppression of CRMP2 expression by bone morphogenetic protein (BMP)-SMAD gradient signaling controls multiple stages of neuronal development.
|
| Sun Y, Fei T, Yang T, Zhang F, Chen YG, Li H, Xu Z.
|
| J Biol Chem 285(50):39039-50. Epub 2010 Oct 6.
2010
|
| 37 | BMP2, BMP4, GDF11, MSTN, TGFB1, WFIKKN1, WFIKKN2
|
| WFIKKN1 and WFIKKN2 bind growth factors TGFβ1, BMP2 and BMP4 but do not inhibit their signalling activity.
|
| Szláma G, Kondás K, Trexler M, Patthy L.
|
| FEBS J 277(24):5040-50. doi: 10.1111/j.1742-4658.2010.07909.x. Epub 2010 Nov 5.
2010
|
| 38 | BMP4
|
| Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.
|
| Suzuki S, Marazita ML, Cooper ME, Miwa N, Hing A, Jugessur A, Natsume N, Shimozato K, Ohbayashi N, Suzuki Y, Niimi T, Minami K, Yamamoto M, Altannamar TJ, Erkhembaatar T, Furukawa H, Daack-Hirsch S, L'heureux J, Brandon CA, Weinberg SM, Neiswanger K, Deleyiannis FW, de Salamanca JE, Vieira AR, Lidral AC, Martin JF, Murray JC.
|
| Am J Hum Genet 84(3):406-11. Epub 2009 Feb 26.
2009
|
| 39 | BMP2, BMP4
|
| Bone morphogenetic proteins are involved in the pathobiology of synovial chondromatosis.
|
| Nakanishi S, Sskamoto K, Yoshitake H, Kino K, Amagasa T, Yamaguchi A.
|
| Biochem Biophys Res Commun 379(4):914-9. Epub 2009 Jan 10.
2009
|
| 40 | BMP4
|
| CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells.
|
| Andersson T, Södersten E, Duckworth JK, Cascante A, Fritz N, Sacchetti P, Cervenka I, Bryja V, Hermanson O.
|
| J Biol Chem. 284(6):3672-81 2009
|
| 41 | BMP4
|
| BMP4 mediates oxidative stress-induced retinal pigment epithelial cell senescence and is overexpressed in age-related macular degeneration.
|
| Zhu D, Wu J, Spee C, Ryan SJ, Hinton DR.
|
| J Biol Chem 284(14):9529-39. Epub 2009 Jan 21.
2009
|
| 42 | BMP4
|
| BMP4-Smad signaling pathway mediates adriamycin-induced premature senescence in lung cancer cells.
|
| Su D, Zhu S, Han X, Feng Y, Huang H, Ren G, Pan L, Zhang Y, Lu J, Huang B.
|
| J Biol Chem 284(18):12153-64. Epub 2009 Mar 6.
2009
|
| 43 | BMP4, GREM1
|
| Bone morphogenetic protein 4 inhibits TGF-beta2 stimulation of extracellular matrix proteins in optic nerve head cells: role of gremlin in ECM modulation.
|
| Zode GS, Clark AF, Wordinger RJ.
|
| Glia 57(7):755-66.
2009
|
| 44 | BMP15, BMP4
|
| Bone morphogenetic protein 15 (BMP15) acts as a BMP and Wnt inhibitor during early embryogenesis.
|
| Di Pasquale E, Brivanlou AH.
|
| J Biol Chem 284(38):26127-36. Epub 2009 Jun 24.PMID: 19553676 2009
|
| 45 | BMP4, SCX
|
| Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction.
|
| Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E.
|
| Dev Cell 17(6):861-73. doi: 10.1016/j.devcel.2009.10.010.
2009
|
| 46 | BMP4, DEL14Q22 , MCOPS6
|
| Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways.
|
| Bakrania P, Efthymiou M, Klein JC, Salt A, Bunyan DJ, Wyatt A, Ponting CP, Martin A, Williams S, Lindley V, Gilmore J, Restori M, Robson AG, Neveu MM, Holder GE, Collin JR, Robinson DO, Farndon P, Johansen-Berg H, Gerrelli D, Ragge NK.
|
| Am J Hum Genet 82(2):304-19. Epub 2008 Jan 31. 2008
|
| 47 | BMP4, CRELD1, GATA4, NKX2-5
|
| Mutations in GATA4, NKX2.5, CRELD1, and BMP4 are infrequently found in patients with congenital cardiac septal defects.
|
| Posch MG, Perrot A, Schmitt K, Mittelhaus S, Esenwein EM, Stiller B, Geier C, Dietz R, Gessner R, Ozcelik C, Berger F.
|
| Am J Med Genet A 146A(2):251-3. No abstract available.
2008
|
| 48 | BMP4, DEL14Q22
|
| Heterozygous deletion at 14q22.1-q22.3 including the BMP4 gene in a patient with psychomotor retardation, congenital corneal opacity and feet polysyndactyly.
|
| Hayashi S, Okamoto N, Makita Y, Hata A, Imoto I, Inazawa J.
|
| Am J Med Genet A m J Med Genet A. 2008 Oct 16. [Epub ahead of print]
2008
|
| 49 | BMP4
|
| Bone morphogenetic protein-4 strongly potentiates growth factor-induced proliferation of mammary epithelial cells.
|
| Montesano R, Sarközi R, Schramek H.
|
| Biochem Biophys Res Commun 374(1):164-8. Epub 2008 Jul 14.
2008
|
| 50 | BMP2, BMP4, BMP6, SOST, WNT10B
|
| Regulation of bone formation by osteoclasts involves Wnt/BMP signaling and the chemokine sphingosine-1-phosphate.
|
| Pederson L, Ruan M, Westendorf JJ, Khosla S, Oursler MJ.
|
| Proc Natl Acad Sci U S A 105(52):20764-9. Epub 2008 Dec 15.
2008
|
| 51 | BMP4
|
| Cyclic dermal BMP signalling regulates stem cell activation during hair regeneration
|
| Plikus, M. V.; Mayer, J. A.; de la Cruz, D.; Baker, R. E.; Maini, P. K.; Maxson, R.; Chuong, C.-M.
|
| Nature 451: 340-344 2008
|
| 52 | BMP4
|
| Type IV collagens regulate BMP signalling in Drosophila
|
| Wang, X.; Harris, R. E.; Bayston, L. J.; Ashe, H. L.
|
| Nature 455: 72-77 2008
|
| 53 | BMP4, SMAD5
|
| BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development.
|
| Porayette P, Paulson RF.
|
| Dev Biol 317(1):24-35. Epub 2008 Feb 15.
2008
|
| 54 | BMP4, SIX2
|
| SIX2 and BMP4 mutations associate with anomalous kidney development.
|
| Weber S, Taylor JC, Winyard P, Baker KF, Sullivan-Brown J, Schild R, Knüppel T, Zurowska AM, Caldas-Alfonso A, Litwin M, Emre S, Ghiggeri GM, Bakkaloglu A, Mehls O, Antignac C, Network E, Schaefer F, Burdine RD.
|
| J Am Soc Nephrol 19(5):891-903. Epub 2008 Feb 27.PMID: 18305125 2008
|
| 55 | BMP4, BMP7, HOXB6, HOXA4
|
| Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias.
|
| Chen T, Li Q, Xu J, Ding K, Wang Y, Wang W, Li S, Shen Y.
|
| Eur J Hum Genet 15(1):23-8. Epub 2006 Sep 27. 2007
|
| 56 | BMP4, BMP5
|
| Over-expression of BMP4 and BMP5 in a child with axial skeletal malformations and heterotopic ossification: A new syndrome.
|
| Feldman GJ, Billings PC, Patel RV, Caron RJ, Guenther C, Kingsley DM, Kaplan FS, Shore EM.
|
| Am J Med Genet A 143(7):699-706. 2007
|
| 57 | HFE2, BMP2, BMP4
|
| Common Variants in the BMP2, BMP4, and HJV Genes of the Hepcidin Regulation Pathway Modulate HFE Hemochromatosis Penetrance.
|
| Milet J, Dehais V, Bourgain C, Jouanolle AM, Mosser A, Perrin M, Morcet J, Brissot P, David V, Deugnier Y, Mosser J.
|
| Am J Hum Genet 81(4):799-807. Epub 2007 Aug 31. 2007
|
| 58 | BMP1, BMP2, BMP4
|
| Bone morphogenetic protein 1 prodomain specifically binds and regulates signaling by bone morphogenetic proteins 2 and 4.
|
| Jasuja R, Ge G, Voss NG, Lyman-Gingerich J, Branam AM, Pelegri FJ, Greenspan DS.
|
| J Biol Chem 282(12):9053-62. Epub 2007 Jan 25.
2007
|
| 59 | BMP4
|
| Effects of TGF-beta-2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma
|
| Wordinger, R. J.; Fleenor, D. L.; Hellberg, P. E.; Pang, I.-H.; Tovar, T. O.; Zode, G. S.; Fuller, J. A.; Clark, A. F.
|
| Invest Ophthalmol Vis Sci. 48: 1191-1200 2007
|
| 60 | BMP4, NOG
|
| Evidence for expansion-based temporal BMP4/NOGGIN interactions in specifying periodontium morphogenesis.
|
| Kim JY, Cho SW, Hwang HJ, Lee MJ, Lee JM, Cai J, Choi SH, Kim CK, Jung HS.
|
| Cell Tissue Res 330(1):123-32. Epub 2007 Jul 6.PMID: 17618464 2007
|
| 61 | BMP4, GREM2
|
| Wnt/beta-catenin signaling regulates expression of PRDC, an antagonist of the BMP-4 signaling pathway.
|
| Im J, Kim H, Kim S, Jho EH.
|
| Biochem Biophys Res Commun 354(1):296-301. Epub 2007 Jan 8.
2007
|
| 62 | BMP4, MGP
|
| Regulation of bone morphogenetic protein-4 by matrix GLA protein in vascular endothelial cells involves activin-like kinase receptor 1.
|
| Yao Y, Zebboudj AF, Shao E, Perez M, Boström K.
|
| J Biol Chem 281(45):33921-30. Epub 2006 Sep 1.
2006
|
| 63 | BMP4
|
| Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour-initiating cells.
|
| Piccirillo SG, Reynolds BA, Zanetti N, Lamorte G, Binda E, Broggi G, Brem H, Olivi A, Dimeco F, Vescovi AL.
|
| Nature 444(7120):761-5. 2006
|
| 64 | BMP4, RUNX2
|
| Different roles of Runx2 during early neural crest-derived bone and tooth development.
|
| James MJ, Jrvinen E, Wang XP, Thesleff I.
|
| J Bone Miner Res 21(7):1034-44. 2006
|
| 65 | BMP4, DMD
|
| Gene expression profiling highlights defective myogenesis in DMD patients and a possible role for bone morphogenetic protein 4.
|
| Sterrenburg E, van der Wees CG, White SJ, Turk R, de Menezes RX, van Ommen GJ, den Dunnen JT, 't Hoen PA.
|
| Neurobiol Dis 23(1):228-36. Epub 2006 May 6. 2006
|
| 66 | BMP4, GREM1
|
| Regulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
|
| Frank NY, Kho AT, Schatton T, Murphy GF, Molloy MJ, Zhan Q, Ramoni MF, Frank MH, Kohane IS, Gussoni E.
|
| J Cell Biol 175(1):99-110. Epub 2006 Oct 2.
2006
|
| 67 | BMP4
|
| Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway
|
| Moreno M, Muńoz R, Aroca F, Labarca M, Brandan E, Larraín J.
|
| EMBO J. 24(7):1397-405 2005
|
| 68 | NKX2-1, BMP4
|
| NKX2.1 regulates transcription of the gene for human bone morphogenetic protein-4 in lung epithelial cells.
|
| Zhu NL, Li C, Xiao J, Minoo P.
|
| Gene 327(1):25-36. 2004
|
| 69 | BMP4, BMP5, BMP6
|
| Effect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cells.
|
| Xu WP, Shiba H, Mizuno N, Uchida Y, Mouri Y, Kawaguchi H, Kurihara H.
|
| Cell Biol Int 28(10):675-82. 2004
|
| 70 | BMP4
|
| Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype
|
| Kan, L.; Hu, M.; Gomes, W. A.; Kessler, J. A.
|
| Am. J. Path. 165: 1107-1115 2004
|
| 71 | BMP4
|
| BMPER, a novel endothelial cell precursor-derived protein, antagonizes bone morphogenetic protein signaling and endothelial cell differentiation
|
| Moser M, Binder O, Wu Y, Aitsebaomo J, Ren R, Bode C, Bautch VL, Conlon FL, Patterson C.
|
| Mol Cell Biol. 23(16):5664-79 2003
|
| 72 | BMP4
|
| An essential role of Bmp4 in the atrioventricular septation of the mouse heart
|
| Jiao, K.; Kulessa, H.; Tompkins, K.; Zhou, Y.; Batts, L.; Baldwin, H. S.; Hogan, B. L. M.
|
| Genes Dev. 17: 2362-2367 2003
|
| 73 | BMP2, BMP4, BMP5, BMP7, NOG
|
| Bone morphogenetic proteins with some comments on fibrodysplasia ossificans progressiva and NOGGIN.
|
| Cohen MM Jr.
|
| Am J Med Genet 109(2):87-92. No abstract available. 2002
|
| 74 | BMP4
|
| Oncogenic beta-catenin is required for bone morphogenetic protein 4 expression in human cancer cells.
|
| Kim JS, Crooks H, Dracheva T, Nishanian TG, Singh B, Jen J, Waldman T.
|
| Cancer Res 62(10):2744-8. 2002
|
| 75 | BMP2, BMP4, BMP7, BMPR1A, BMPR1B, BMPR2, GREM1
|
| Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues.
|
| Wordinger RJ, Agarwal R, Talati M, Fuller J, Lambert W, Clark AF.
|
| Mol Vis 8:241-50. 2002
|
| 76 | BMP4, CHRD, TWSG1
|
| Twisted gastrulation is a conserved extracellular BMP antagonist.
|
| Ross JJ, Shimmi O, Vilmos P, Petryk A, Kim H, Gaudenz K, Hermanson S, Ekker SC, O'Connor MB, Marsh JL.
|
| Nature 410(6827):479-83. 2001
|
| 77 | BMP4, CHRD, TWSG1
|
| Twisted gastrulation can function as a BMP antagonist.
|
| Chang C, Holtzman DA, Chau S, Chickering T, Woolf EA, Holmgren LM, Bodorova J, Gearing DP, Holmes WE, Brivanlou AH.
|
| Nature 410(6827):483-7. 2001
|
| 78 | BMP4, BMP7, GLI1, GLI3
|
| Characterization of human bone morphogenetic protein (BMP)-4 and -7 gene promoters: activation of BMP promoters by Gli, a sonic hedgehog mediator.
|
| Kawai S, Sugiura T.
|
| Bone 29(1):54-61. 2001
|
| 79 | BMP4
|
| BMP4 plays a key role in left-right patterning in chick embryos by maintaining Sonic hedgehog asymmetry
|
| Monsoro-Burq, A.-H.; le Douarin, N. M.
|
| Molec. Cell 7: 789-799 2001
|
| 80 | BMP4, NOG
|
| Linkage exclusion and mutational analysis of the noggin gene in patients with fibrodysplasia ossificans progressiva (FOP)
|
| Xu MQ, Feldman G, Le Merrer M , Shugart YY, Glaser DL, Urtizberea JA, Fardeau M, Connor JM, Triffitt J, Smith R, Shore EM, Kaplan FS.
|
| Clin Genet 58(4):291-8. 2000
|
| 81 | BMP4
|
| Bone morphogenetic protein inhibits ovarian androgen production.
|
| Dooley CA, Attia GR, Rainey WE, Moore DR, Carr BR.
|
| J Clin Endocrinol Metab 85(9):3331-7. 2000
|
| 82 | BMP4
|
| Requirement of Bmp8b for the generation of primordial germ cells in the mouse
|
| Ying Y, Liu XM, Marble A, Lawson KA, Zhao GQ.
|
| Mol Endocrinol. 14(7):1053-63 2000
|
| 83 | BMP4
|
| Noggin is a negative regulator of neuronal differentiation in developing neocortex
|
| Li W, LoTurco JJ.
|
| Dev Neurosci. 22(1-2):68-73 2000
|
| 84 | BMP4
|
| USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney
|
| Yanagita M, Oka M, Watabe T, Iguchi H, Niida A, Takahashi S, Akiyama T, Miyazono K, Yanagisawa M, Sakurai T
|
| Biochem Biophys Res Commun. 16(2):490-500 2000
|
| 85 | BMP4
|
| Independent regulation of Dlx2 expression in the epithelium and mesenchyme of the first branchial arch
|
| Thomas, B. L.; Liu, J. K.; Rubenstein, J. L. R.; Sharpe, P. T.
|
| Development 127: 217-224 2000
|
| 86 | BMP4
|
| Functional characterization of two promoters in the human bone morphogenetic protein-4 gene.
|
| Van den Wijngaard A, et al.
|
| J Bone Miner Res 14(8):1432-41 1999
|
| 87 | BMP4
|
| The E-Box motif, recognized by tissue-specific nuclear factor(s), is important for BMP-4 gene expression in osteogenic cells.
|
| Kawasaki S, Ebara S, Nakayama K, Takaoka K.
|
| Biochem Biophys Res Commun 263(2):560-5. 1999
|
| 88 | BMP1, BMP15, BMP2, BMP3, GDF10, BMP4, BMP5, BMP6, BMP7, BMPR1A, BMPR1APS1, BMPR1B, BMPR2, GDF1, GDF2, GDF3, GDF5, MSTN, GDF9
|
| Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.
|
| Constam DB, Robertson EJ.
|
| J Cell Biol 144(1):139-49. 1999
|
| 89 | PAX3, BMP2, BMP4
|
| The importance of timing differentiation during limb muscle development.
|
| Amthor H, et al.
|
| Curr Biol 8(11):642-52. 1998
|
| 90 | BMP4, FGF4
|
| Antagonistic effects of FGF4 on BMP induction of apoptosis and chondrogenesis in the chick limb bud.
|
| Buckland RA, et al.
|
| Mech Dev 71(1-2):143-50. 1998
|
| 91 | MSX2, BMP4
|
| Ectopic expression of Msx-2 in posterior limb bud mesoderm impairs limb morphogenesis while inducing BMP-4 expression, inhibiting cell proliferation, and promoting apoptosis.
|
| Ferrari D, et al.
|
| Dev Biol 197(1):12-24. 1998
|
| 92 | BMP4
|
| Mutational screening of the bone morphogenetic protein 4 gene in a family with fibrodysplasia ossificans progressiva.
|
| Xu M, et al.
|
| Clin Orthop (346):53-8 1998
|
| 93 | BMP4, FURIN
|
| BMP-4 is proteolytically activated by furin and/or PC6 during vertebrate embryonic development.
|
| Cui Y, Jean F, Thomas G, Christian JL.
|
| EMBO J 17(16):4735-43. 1998
|
| 94 | BMP4
|
| The human bone morphogenetic protein 4 (BMP-4) gene: molecular structure and transcriptional regulation
|
| Shore, E. M.; Xu, M.; Shah, P. B.; Janoff, H. B.; Hahn, G. V.; Deardorff, M. A.; Sovinsky, L.; Spinner, N. B.; Zasloff, M. A.; Wozney, J. M.; Kaplan, F. S.
|
| Calcif. Tissue Int. 63: 221-229 1998
|
| 95 | BMP4
|
| Genomic organization of the human bone morphogenetic protein-4 gene : molecular basis for multiple transcripts.
|
| van den Wijngaard A, et al.
|
| Biochem Biophys Res Commun 219 : 789-794. 1996
|
| 96 | BMP4
|
| Requirement for BMP signaling in interdigital apoptosis and scale formation.
|
| Zou H, et al.
|
| Science 272(5262):738-41. 1996
|
| 97 | BMP4, NOG
|
| The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4.
|
| Zimmerman LB, et al.
|
| Cell 86(4):599-606. 1996
|
| 98 | BMP4, SMAD1
|
| A human Mad protein acting as a BMP-regulated transcriptional activator.
|
| Liu F, Hata A, Baker JC, Doody J, Carcamo J, Harland RM, Massague J.
|
| Nature 381(6583):620-3. 1996
|
| 99 | BMP4
|
| Fine mapping of the human bone morphogenetic protein-4 gene (BMP4) to chromosome 14q22-q23 by in situ hybridization.
|
| Van den Wijngaard A, et al.
|
| Genomics 27 : 559-560. 1995
|
| 100 | BMP4
|
| Cloning and characterization of a human type II receptor for bone morphogenetic proteins
|
| Rosenzweig BL, Imamura T, Okadome T, Cox GN, Yamashita H, ten Dijke P, Heldin CH, Miyazono K.
|
| Proc Natl Acad Sci U S A. 92(17):7632-6 1995
|
| 101 | BMP4
|
| Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4
|
| ten Dijke P, Yamashita H, Sampath TK, Reddi AH, Estevez M, Riddle DL, Ichijo H, Heldin CH, Miyazono K.
|
| J Biol Chem. 269(25):16985-8 1994
|
| 102 | BMP4
|
| Basic science and pathology. Chromosomal assignment of the human gene for bone morphogenetic protein 4.
|
| Tabas JA, et al.
|
| Clin Orthop 293 : 310-316. 1993
|
| 103 | BMP1, BMP2, BMP3, BMP4, BMP5, BMP6, BMP7
|
| Expression of bone morphogenetic proteins in human prostatic adenocarcinoma and benign prostatic hyperplasia.
|
| Bentley H, et al.
|
| Br J Cancer 66 : 1159-1163. 1992
|