Citations for
1BHMT, CBS
Association between BHMT and CBS gene promoter methylation with the efficacy of folic acid therapy in patients with hyperhomocysteinemia.
Huang X, Li D, Zhao Q, Zhang C, Ren B, Yue L, Du B, Godfrey O, Wang X, Zhang W.
J Hum Genet 64(12):1227-1235. doi: 10.1038/s10038-019-0672-7. Epub 2019 Sep 27. 2019
2BHMT
Long non-coding RNA Bhmt-AS attenuates hepatic gluconeogenesis via modulation of Bhmt expression.
Shen X, Zhang Y, Zhang X, Yao Y, Zheng Y, Cui X, Liu C, Wang Q, Li JZ.
Biochem Biophys Res Commun 516(1):215-221. doi: 10.1016/j.bbrc.2019.06.008. Epub 2019 Jun 14. 2019
3BHMT
Exome sequencing of cases with neural tube defects identifies candidate genes involved in one-carbon/vitamin B12 metabolisms and Sonic Hedgehog pathway.
Renard E, Chéry C, Oussalah A, Josse T, Perrin P, Tramoy D, Voirin J, Klein O, Leheup B, Feillet F, Guéant-Rodriguez RM, Guéant JL.
Hum Genet 138(7):703-713. doi: 10.1007/s00439-019-02015-7. Epub 2019 May 28. 2019
4BHMT
Association between the BHMT gene rs3733890 polymorphism and the efficacy of oral folate therapy in patients with hyperhomocysteinemia.
Ren B, Tian D, Wang L, Han H, Wang W, Tian H, Yue L, Zhang W.
Ann Hum Genet 83(6):434-444. doi: 10.1111/ahg.12326. Epub 2019 May 20. 2019
5BHMT, BHMT2, DMGDH
Evidence of interaction between genes in the folate/homocysteine metabolic pathway in controlling risk of non-syndromic oral cleft.
Wang P, Wu T, Schwender H, Wang H, Shi B, Wang ZQ, Yuan Y, Liu DJ, Wang MY, Li J, Zhou ZB, Zhu HP, Beaty TH.
Oral Dis 24(5):820-828. doi: 10.1111/odi.12831. Epub 2018 Apr 24. 2018
6BHMT, BHMT2, HMGB1, YWHAE
Identification of hepatic protein-protein interaction targets for betaine homocysteine S-methyltransferase.
Garrido F, Pacheco M, Vargas-Martínez R, Velasco-García R, Jorge I, Serrano H, Portillo F, Vázquez J, Pajares MÁ.
PLoS One 13(6):e0199472. doi: 10.1371/journal.pone.0199472. eCollection 2018. 2018
7BHMT
Reduced brain volume and impaired memory in betaine homocysteine S-methyltransferase knockout mice.
Prieur EAK, Pjetri E, Zeisel SH, Jadavji NM.
Appl Physiol Nutr Metab 42(11):1228-1231. doi: 10.1139/apnm-2017-0182. Epub 2017 Jul 17. 2017
8BHMT
Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy.
Colomina JM, Cavallé-Busquets P, Fernàndez-Roig S, Solé-Navais P, Fernandez-Ballart JD, Ballesteros M, Ueland PM, Meyer K, Murphy MM.
Nutrients 8(10). pii: E621. 2016
9BHMT
Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis.
Jin B, Gong Z, Yang N, Huang Z, Zeng S, Chen H, Hu S, Pan G.
Tumour Biol 37(5):5911-7. doi: 10.1007/s13277-015-4443-6. Epub 2015 Nov 23. 2016
10BHMT, BHMT2
Evolutionary Analyses and Natural Selection of Betaine-Homocysteine S-Methyltransferase (BHMT) and BHMT2 Genes.
Ganu RS, Ishida Y, Koutmos M, Kolokotronis SO, Roca AL, Garrow TA, Schook LB.
PLoS One 10(7):e0134084. doi: 10.1371/journal.pone.0134084. eCollection 2015. 2015
11BHMT
Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury.
Ma H, Ning J, Jin X, Mao C, Bu X, Wang M, Liu H, Wang K, Lausted C, Hood L, Chen J, Hu Z.
Biomarkers 19(7):578-84. doi: 10.3109/1354750X.2014.951880. Epub 2014 Aug 21. 2014
12BHMT
Specific potassium ion interactions facilitate homocysteine binding to betaine-homocysteine S-methyltransferase.
Mládková J, Hladílková J, Diamond CE, Tryon K, Yamada K, Garrow TA, Jungwirth P, Koutmos M, Jiráček J.
Proteins 82(10):2552-64. doi: 10.1002/prot.24619. Epub 2014 Jun 17. 2014
13BHMT
Mouse betaine-homocysteine S-methyltransferase deficiency reduces body fat via increasing energy expenditure and impairing lipid synthesis and enhancing glucose oxidation in white adipose tissue.
Teng YW, Ellis JM, Coleman RA, Zeisel SH.
J Biol Chem 287(20):16187-98. doi: 10.1074/jbc.M111.303255. Epub 2012 Feb 23. 2012
14BHMT
A splicing variant leads to complete loss of function of betaine-homocysteine methyltransferase (BHMT) gene in hepatocellular carcinoma.
Pellanda H, Namour F, Fofou-Caillierez M, Bressenot A, Alberto JM, Chéry C, Ayav A, Bronowicki JP, Guéant JL, Forges T.
Int J Biochem Cell Biol 44(2):385-92. doi: 10.1016/j.biocel.2011.11.014. Epub 2011 Nov 26. 2012
15BHMT
BHMT gene polymorphisms as risk factors for cleft lip and cleft palate in a Chinese population.
Hu Y, Chen E, Mu Y, Li J, Chen R.
Biomed Environ Sci 24(2):89-93. doi: 10.3967/0895-3988.2011.02.001. 2011
16BHMT
Betaine-homocysteine methyltransferase: human liver genotype-phenotype correlation.
Feng Q, Kalari K, Fridley BL, Jenkins G, Ji Y, Abo R, Hebbring S, Zhang J, Nye MD, Leeder JS, Weinshilboum RM.
Mol Genet Metab 102(2):126-33. doi: 10.1016/j.ymgme.2010.10.010. Epub 2010 Oct 21. 2011
17BHMT, BHMT2
New evidence for the role of cystathionine beta-synthase in non-syndromic cleft lip with or without cleft palate.
Martinelli M, Masiero E, Carinci F, Morselli PG, Pezzetti F, Scapoli L.
Eur J Oral Sci 119(3):193-7. doi: 10.1111/j.1600-0722.2011.00824.x. Epub 2011 May 5. 2011
18BHMT, BHMT2
Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts.
Mostowska A, Hozyasz KK, Biedziak B, Misiak J, Jagodzinski PP.
Eur J Oral Sci 118(4):325-32. doi: 10.1111/j.1600-0722.2010.00757.x. 2010
19BHMT, BHMT2
Polymorphisms located in the region containing BHMT and BHMT2 genes as maternal protective factors for orofacial clefts.
Mostowska A, Hozyasz KK, Biedziak B, Misiak J, Jagodzinski PP.
Eur J Oral Sci 118(4):325-32. doi: 10.1111/j.1600-0722.2010.00757.x. 2010
20BHMT, BHMT2
Human betaine-homocysteine methyltransferase (BHMT) and BHMT2: common gene sequence variation and functional characterization.
Li F, Feng Q, Lee C, Wang S, Pelleymounter LL, Moon I, Eckloff BW, Wieben ED, Schaid DJ, Yee V, Weinshilboum RM.
Mol Genet Metab 94(3):326-35. Epub 2008 May 23. 2008
21BHMT
Polymorphisms in methionine synthase reductase and betaine-homocysteine S-methyltransferase genes: risk of placental abruption.
Ananth CV, Elsasser DA, Kinzler WL, Peltier MR, Getahun D, Leclerc D, Rozen RR; New Jersey Placental Abruption Study Investigators.
Mol Genet Metab. 91(1):104-10. Epub 2007 Mar 26. 2007
22BHMT
Betaine-Homocysteine Methyltransferase (BHMT): Genomic Sequencing and Relevance to Hyperhomocysteinemia and Vascular Disease in Humans.
Heil SG, Lievers KJ, Boers GH, Verhoef P, den Heijer M, Trijbels FJ, Blom HJ.
Mol Genet Metab 71(3):511-519. 2000
23BHMT, BHMT2
Betaine-homocysteine methyltransferase-2: cDNA cloning, gene sequence, physical mapping, and expression of the human and mouse genes.
Chadwick LH, McCandless SE, Silverman GL, Schwartz S, Westaway D, Nadeau JH.
Genomics 70(1):66-73. 2000
24BHMT
Betaine-homocysteine methyltransferase expression in porcine and human tissues and chromosomal localization of the human gene.
Sunden SL, Renduchintala MS, Park EI, Miklasz SD, Garrow TA.
Arch Biochem Biophys 345(1):171-4. 1997
25BHMT
Purification, kinetic properties, and cDNA cloning of mammalian betaine-homocysteine methyltransferase.
Garrow TA.
J Biol Chem 271(37):22831-8. 1996