Citations for
1ACTL6B, BDNF
BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens.
White AO, Kramár EA, López AJ, Kwapis JL, Doan J, Saldana D, Davatolhagh MF, Alaghband Y, Blurton-Jones M, Matheos DP, Wood MA.
Nat Commun 7:11725. doi: 10.1038/ncomms11725. 2016
2BDNF, LRIG1, NTRK2
Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling.
Alsina FC, Hita FJ, Fontanet PA, Irala D, Hedman H, Ledda F, Paratcha G.
EMBO Rep 17(4):601-16. doi: 10.15252/embr.201541218. Epub 2016 Mar 2. 2016
3BDNF, CYFIP1, EIF4E, MKNK1
BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.
Genheden M, Kenney JW, Johnston HE, Manousopoulou A, Garbis SD, Proud CG.
J Neurosci 35(3):972-84. doi: 10.1523/JNEUROSCI.2641-14.2015. 2015
4BDNF, ELAVL4
HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.
Vanevski F, Xu B.
PLoS One 10(2):e0117264. doi: 10.1371/journal.pone.0117264. eCollection 2015. 2015
5BDNF, NTRK2, SLC6A5, SLC6A9
BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes.
Aroeira RI, Sebastião AM, Valente CA.
Glia 63(12):2181-97. doi: 10.1002/glia.22884. 2015
6BDNF, CRP
Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women.
Noren Hooten N, Ejiogu N, Zonderman AB, Evans MK.
Mediators Inflamm 2015:516783. doi: 10.1155/2015/516783. Epub 2015 May 26. 2015
7BBS4, BDNF, NTRK2
BBS4 Is Necessary for Ciliary Localization of TrkB Receptor and Activation by BDNF.
Leitch CC, Zaghloul NA.
PLoS One 9(5):e98687. doi: 10.1371/journal.pone.0098687. eCollection 2014. 2014
8BDNF, NTF3
Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma.
Wan G, Gómez-Casati ME, Gigliello AR, Liberman MC, Corfas G.
Elife 3. doi: 10.7554/eLife.03564. 2014
9BDNF, NTF3
Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus.
Rak K, Völker J, Frenz S, Scherzad A, Schendzielorz P, Radeloff A, Jablonka S, Hagen R, Mlynski R.
Neuroreport 25(12):960-4. doi: 10.1097/WNR.0000000000000220. 2014
10AICDA, BDNF
Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons.
Ratnu VS, Wei W, Bredy TW.
Eur J Neurosci 40(7):3032-9. doi: 10.1111/ejn.12678. 2014
11BDNF, ELP4
Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.
Gkampeta A, Fidani L, Clarimón J, Kalinderi K, Katopodi T, Zafeiriou D, Pavlou E.
Epilepsy Res 108(10):1734-9. doi: 10.1016/j.eplepsyres.2014.09.005. 2014
12BDNF, DEL2P25, SIM1, TRKB
Obesity with associated developmental delay and/or learning disability in patients exhibiting additional features: Report of novel pathogenic copy number variants.
D'Angelo CS, Kohl I, Varela MC, de Castro CI, Kim CA, Bertola DR, Lourenço CM, Perez AB, Koiffmann CP.
Am J Med Genet A 161(3):479-86. doi: 10.1002/ajmg.a.35761. Epub 2013 Feb 7. 2013
13BDNF, ERBB2, NRG1
RET and NRG1 interplay in Hirschsprung disease.
Gui H, Tang WK, So MT, Proitsi P, Sham PC, Tam PK, Sau-Wai Ngan E, Cherny SS, Garcia-Barceló MM.
Hum Genet 132(5):591-600. doi: 10.1007/s00439-013-1272-9. Epub 2013 Feb 12. 2013
14BDNF, SIK1
Role of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNF.
Finsterwald C, Carrard A, Martin JL.
PLoS One 8(1):e54545. doi: 10.1371/journal.pone.0054545. Epub 2013 Jan 22. 2013
15BDNF, ELAVL4
HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.
Allen M, Bird C, Feng W, Liu G, Li W, Perrone-Bizzozero NI, Feng Y.
PLoS One 8(1):e55718. doi: 10.1371/journal.pone.0055718. Epub 2013 Jan 31. 2013
16BDNF, CREB1, NR4A2
Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival.
Barneda-Zahonero B, Servitja JM, Badiola N, Miñano-Molina AJ, Fadó R, Saura CA, Rodríguez-Alvarez J.
J Biol Chem 287(14):11351-62. doi: 10.1074/jbc.M111.272427. Epub 2012 Jan 31. 2012
17BDNF, NTRK2
Expression of TrkB and BDNF is associated with poor prognosis in non-small cell lung cancer.
Okamura K, Harada T, Wang S, Ijichi K, Furuyama K, Koga T, Okamoto T, Takayama K, Yano T, Nakanishi Y.
Lung Cancer 78(1):100-6. doi: 10.1016/j.lungcan.2012.07.011. Epub 2012 Aug 18. 2012
18BDNF, MMP9
Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder.
Yoshida T, Ishikawa M, Niitsu T, Nakazato M, Watanabe H, Shiraishi T, Shiina A, Hashimoto T, Kanahara N, Hasegawa T, Enohara M, Kimura A, Iyo M, Hashimoto K.
PLoS One 7(8):e42676. doi: 10.1371/journal.pone.0042676. Epub 2012 Aug 3. 2012
19BDNF
Brain-derived neurotrophic factor in primary headaches.
Fischer M, Wille G, Klien S, Shanib H, Holle D, Gaul C, Broessner G.
J Headache Pain 13(6):469-75. doi: 10.1007/s10194-012-0454-5. Epub 2012 May 15. 2012
20BDNF
Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults.
Driscoll I, Martin B, An Y, Maudsley S, Ferrucci L, Mattson MP, Resnick SM.
PLoS One 7(4):e35217. doi: 10.1371/journal.pone.0035217. Epub 2012 Apr 16. 2012
21BDNF
Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration.
Wilhelm JC, Xu M, Cucoranu D, Chmielewski S, Holmes T, Lau KS, Bassell GJ, English AW.
J Neurosci 32(14):5002-9. doi: 10.1523/JNEUROSCI.1411-11.2012. 2012
22BDNF, COMT
Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity.
Witte AV, Kürten J, Jansen S, Schirmacher A, Brand E, Sommer J, Flöel A.
J Neurosci 32(13):4553-61. doi: 10.1523/JNEUROSCI.6010-11.2012. 2012
23BDNF, RACK1, YWHAZ
Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription.
Neasta J, Kiely PA, He DY, Adams DR, O'Connor R, Ron D.
J Biol Chem 287(1):322-36. doi: 10.1074/jbc.M111.272195. Epub 2011 Nov 8. 2012
24BDNF, NTRK2
Expression of brain-derived neurotrophic factor and TrkB receptor in the sudden infant death syndrome brainstem.
Tang S, Machaalani R, Waters KA.
Respir Physiol Neurobiol 180(1):25-33. doi: 10.1016/j.resp.2011.10.004. Epub 2011 Oct 14. 2012
25BDNF, DEL16P112D, DEL16P112P, SIM1, TRKB
Copy number variants in obesity-related syndromes: review and perspectives on novel molecular approaches.
D'Angelo CS, Koiffmann CP.
J Obes 2012:845480. doi: 10.1155/2012/845480. Epub 2012 Dec 17. 2012
26BDNF, SOD2
Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.
He T, Katusic ZS.
Microvasc Res 83(3):366-71. doi: 10.1016/j.mvr.2012.01.001. Epub 2012 Jan 9. 2012
27BDNF, PGRMC1
Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling.
Su C, Cunningham RL, Rybalchenko N, Singh M.
Endocrinology 153(9):4389-400. doi: 10.1210/en.2011-2177. Epub 2012 Jul 9. 2012
28BDNF, PARD3, RAC1
Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.
Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SO.
J Biol Chem 287(2):1600-8. doi: 10.1074/jbc.M111.312736. Epub 2011 Nov 29. 2012
29BDNF, NFATC4
Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus.
Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Nguyen T, Elnaggar MY, Pedroarena CM, Molkentin JD, Di Giovanni S.
Proc Natl Acad Sci U S A 109(23):E1499-508. doi: 10.1073/pnas.1202068109. Epub 2012 May 14. 2012
30BDNF
BDNF is a negative modulator of morphine action.
Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, Lobo MK, Neve RL, Russo SJ, Han MH, Nestler EJ.
Science 338(6103):124-8. doi: 10.1126/science.1222265. 2012
31BDNF, DEL11PO
11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity.
Shinawi M, Sahoo T, Maranda B, Skinner SA, Skinner C, Chinault C, Zascavage R, Peters SU, Patel A, Stevenson RE, Beaudet AL.
Am J Med Genet A 155(6):1272-80. doi: 10.1002/ajmg.a.33878. Epub 2011 May 12. 2011
32BDNF, GDNF, S100B
S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk.
Li R, Xia W, Zhang Z, Wu K.
PLoS One 6(6):e21663. Epub 2011 Jun 27. 2011
33BDNF
Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene.
Sears C, Markie D, Olds R, Fitches A.
Bipolar Disord 13(7-8):630-7. doi: 10.1111/j.1399-5618.2011.00955.x. 2011
34BDNF, NTRK2
Self-amplifying autocrine actions of BDNF in axon development.
Cheng PL, Song AH, Wong YH, Wang S, Zhang X, Poo MM.
Proc Natl Acad Sci U S A 108(45):18430-5. doi: 10.1073/pnas.1115907108. Epub 2011 Oct 24. 2011
35BDNF, NTRK2
Expression of TrkB and BDNF in human cochlea-an immunohistochemical study.
Liu W, Kinnefors A, Boström M, Rask-Andersen H.
Cell Tissue Res 345(2):213-21. doi: 10.1007/s00441-011-1209-3. Epub 2011 Jul 8. 2011
36BDNF
Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene.
Pruunsild P, Sepp M, Orav E, Koppel I, Timmusk T.
J Neurosci 31(9):3295-308. doi: 10.1523/JNEUROSCI.4540-10.2011. 2011
37BDNF, NTRK2, SOD1
The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease.
Zhai J, Zhou W, Li J, Hayworth CR, Zhang L, Misawa H, Klein R, Scherer SS, Balice-Gordon RJ, Kalb RG.
Hum Mol Genet. 20(21):4116-31 2011
38BDNF
Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging.
Zeng Y, Tan M, Kohyama J, Sneddon M, Watson JB, Sun YE, Xie CW.
J Neurosci 31(49):17800-10. doi: 10.1523/JNEUROSCI.3878-11.2011. 2011
39BDNF, HAP1
Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release.
Wu LL, Fan Y, Li S, Li XJ, Zhou XF.
J Biol Chem 285(8):5614-23. Epub 2009 Dec 7. 2010
40BDNF
BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function.
Spencer JL, Waters EM, Milner TA, Lee FS, McEwen BS.
Proc Natl Acad Sci U S A 107(9):4395-400. Epub 2010 Feb 8.PMID: 20142488 2010
41BDNF
Genetic variants in the BDNF gene and therapeutic response to risperidone in schizophrenia patients: a pharmacogenetic study.
Xu M, Li S, Xing Q, Gao R, Feng G, Lin Z, St Clair D, He L.
Eur J Hum Genet 18(6):707-12. Epub 2010 Jan 20.PMID: 20087404 2010
42BDNF, RAI1, SMS
Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome.
Burns B, Schmidt K, Williams SR, Kim S, Girirajan S, Elsea SH.
Hum Mol Genet 19(20):4026-42. Epub 2010 Jul 27.PMID: 20663924 2010
43BDNF, NTRK2
Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus.
Tang S, Machaalani R, Waters KA.
Brain Res 1354:1-14. Epub 2010 Jul 29.PMID: 20673758 2010
44BDNF, NTRK2
Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism.
Correia CT, Coutinho AM, Sequeira AF, Sousa IG, Lourenço Venda L, Almeida JP, Abreu RL, Lobo C, Miguel TS, Conroy J, Cochrane L, Gallagher L, Gill M, Ennis S, Oliveira GG, Vicente AM.
Genes Brain Behav 9(7):841-8. doi: 10.1111/j.1601-183X.2010.00627.x. Epub 2010 Aug 19.PMID: 20662941 2010
45BDNF, EEF2, EEF2K
Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis.
Verpelli C, Piccoli G, Zibetti C, Zanchi A, Gardoni F, Huang K, Brambilla D, Di Luca M, Battaglioli E, Sala C.
J Neurosci 30(17):5830-42. doi: 10.1523/JNEUROSCI.0119-10.2010. 2010
46BDNF, FTO, HSPA1B, MC4R, TMEM18
Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K.
Nat Genet 41(1):18-24. Epub 2008 Dec 14. 2009
47BDNF, REST
Remote control of activity-dependent BDNF gene promoter-I transcription mediated by REST/NRSF.
Hara D, Fukuchi M, Miyashita T, Tabuchi A, Takasaki I, Naruse Y, Mori N, Kondo T, Tsuda M.
Biochem Biophys Res Commun 384(4):506-11. Epub 2009 May 6. 2009
48BDNF, FAIM2, GNPDA2, MC4R, SEC16B, TMEM18
Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y.
J Hum Genet 54(12):727-31. Epub 2009 Oct 23. 2009
49BDNF
Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.
Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, Chiba AA, Tuszynski MH.
Nat Med. 15(3):331-7 2009
50BDNF
New insights into brain BDNF function in normal aging and Alzheimer disease.
Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S.
Brain Res Rev rain Res Rev. 2008 Aug 3. [Epub ahead of print] 2008
51BDNF, WAGR, WAGRO
Brain-derived neurotrophic factor and obesity in the WAGR syndrome.
Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL, Uhl GR, Rennert OM, Yanovski JA.
N Engl J Med 359(9):918-27. Erratum in: N Engl J Med. 2008 Sep 25;359(13):1414. 2008
52BDNF, HD
Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease.
Zuccato C, Marullo M, Conforti P, MacDonald ME, Tartari M, Cattaneo E.
Brain Pathol 18(2):225-38. Epub 2007 Dec 17. 2008
53BDNF, HD, HTT
Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.
Zala D, Colin E, Rangone H, Liot G, Humbert S, Saudou F.
Hum Mol Genet 17(24):3837-46. Epub 2008 Sep 4. 2008
54AREG, ARHGAP, BDNF, EPHA4, GFPT2, GRIA3, NEFM, PENK, PMCH, SLC16A6, SYT1
Gene expression pattern of functional neuronal cells derived from human bone marrow mesenchymal stromal cells.
Tondreau T, Dejeneffe M, Meuleman N, Stamatopoulos B, Delforge A, Martiat P, Bron D, Lagneaux L.
BMC Genomics 9:166.PMID: 18405367 2008
55BDNF, NTRK2
Retinal TrkB receptors regulate neural development in the inner, but not outer, retina.
Grishanin RN, Yang H, Liu X, Donohue-Rolfe K, Nune GC, Zang K, Xu B, Duncan JL, Lavail MM, Copenhagen DR, Reichardt LF.
Mol Cell Neurosci 38(3):431-43. Epub 2008 Apr 22. 2008
56BDNF
BDNF is essential to promote persistence of long-term memory storage.
Bekinschtein P, Cammarota M, Katche C, Slipczuk L, Rossato JI, Goldin A, Izquierdo I, Medina JH.
Proc Natl Acad Sci U S A. 105(7):2711-6. 2008
57BDNF
Genetic variants in brain-derived neurotrophic factor associated with Alzheimer's disease.
Huang R, Huang J, Cathcart H, Smith S, Poduslo SE.
J Med Genet 44(2):e66. 2007
58BDNF
Brain-derived neurotrophic factor and risk of schizophrenia: an association study and meta-analysis.
Qian L, Zhao J, Shi Y, Zhao X, Feng G, Xu F, Zhu S, He L.
Biochem Biophys Res Commun 353(3):738-43. Epub 2006 Dec 22. 2007
59BDNF, SPRY2
Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival.
Gross I, Armant O, Benosman S, de Aguilar JL, Freund JN, Kedinger M, Licht JD, Gaiddon C, Loeffler JP.
Cell Death Differ 14(10):1802-12. Epub 2007 Jun 29. 2007
60BDNF, BDNFOS
Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters.
Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T.
Genomics 90(3):397-406. Epub 2007 Jul 12. 2007
61BDNF
Association study of the brain-derived neurotropic factor (BDNF) gene in attention deficit hyperactivity disorder.
Lee J, Laurin N, Crosbie J, Ickowicz A, Pathare T, Malone M, Tannock R, Kennedy JL, Schachar R, Barr CL.
Am J Med Genet B Neuropsychiatr Genet 144(8):976-81. 2007
62BDNF
The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study.
Rosa A, Cuesta MJ, Fatjo-Vilas M, Peralta V, Zarzuela A, Fananas L.
Am J Med Genet B Neuropsychiatr Genet 141(2):135-8. 2006
63BDNF
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior.
Chen ZY, Jing D, Bath KG, Ieraci A, Khan T, Siao CJ, Herrera DG, Toth M, Yang C, McEwen BS, Hempstead BL, Lee FS.
Science 314(5796):140-3. 2006
64BDNF
Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene.
Gray J, Yeo GS, Cox JJ, Morton J, Adlam AL, Keogh JM, Yanovski JA, El Gharbawy A, Han JC, Tung YC, Hodges JR, Raymond FL, O'rahilly S, Farooqi IS.
Diabetes 55(12):3366-71. 2006
65BDNF
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ.
Science. 311(5762):864-8. 2006
66BDNF
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor.
Li Y, Jia YC, Cui K, Li N, Zheng ZY, Wang YZ, Yuan XB.
Nature 434(7035):894-8. Epub 2005 Mar 9. 2005
67BDNF
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain.
Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y.
Nature 438(7070):1017-21. 2005
68BDNF, CCHS3
Neurotrophic factor expression in three infants with Ondine's curse.
Chiaretti A, Zorzi G, Di Rocco C, Genovese O, Antonelli A, Piastra M, Polidori G, Aloe L.
Pediatr Neurol 33(5):331-6. 2005
69BDNF
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.
Chen ZY, Ieraci A, Teng H, Dall H, Meng CX, Herrera DG, Nykjaer A, Hempstead BL, Lee FS.
J Neurosci. 25(26):6156-66. 2005
70BDNF
Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.
Ribases M, Gratacos M, Fernandez-Aranda F, Bellodi L, Boni C, Anderluh M, Cavallini MC, Cellini E, Di Bella D, Erzegovesi S, Foulon C, Gabrovsek M, Gorwood P, Hebebrand J, Hinney A, Holliday J, Hu X, Karwautz A, Kipman A, Komel R, Nacmias B, Remschmidt H, Ricca V, Sorbi S, Wagner G, Treasure J, Collier DA, Estivill X.
Hum Mol Genet 13(12):1205-12. Epub 2004 Apr 28. 2004
71BDNF, HTT, HAP1, DCTN1
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F.
Cell 118(1):127-38. 2004
72BDNF, HD
Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J.
J Neurosci 24(35):7727-39. 2004
73BDNF, CFL1
Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.
Gehler S, Shaw AE, Sarmiere PD, Bamburg JR, Letourneau PC.
J Neurosci 24(47):10741-9. 2004
74BDNF
The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival.
Sadakata T, Mizoguchi A, Sato Y, Katoh-Semba R, Fukuda M, Mikoshiba K, Furuichi T.
J Neurosci. 24(1):43-52. 2004
75BDNF
The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR.
Cell 112(2):257-69. 2003
76BDNF
Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder.
Hall D, Dhilla A, Charalambous A, Gogos JA, Karayiorgou M.
Am J Hum Genet 73(2):370-6. Epub 2003 Jun 27. 2003
77BDNF
Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset.
Hong CJ, Liu HC, Liu TY, Lin CH, Cheng CY, Tsai SJ.
Neurosci Lett 353(1):75-7. 2003
78BDNF
The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.
Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL.
Am J Hum Genet 71(3):651-5. 2002
79BDNF, NTF4, NTRK2
A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4.
Naylor RL, Robertson AG, Allen SJ, Sessions RB, Clarke AR, Mason GG, Burston JJ, Tyler SJ, Wilcock GK, Dawbarn D.
Biochem Biophys Res Commun 291(3):501-7. 2002
80BDNF, NTRK2, NTRK3
Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.
Postigo A, Calella AM, Fritzsch B, Knipper M, Katz D, Eilers A, Schimmang T, Lewin GR, Klein R, Minichiello L.
Genes Dev 16(5):633-45. 2002
81BDNF, NTRK2, SCN11A
Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9.
Blum R, Kafitz KW, Konnerth A.
Nature 419(6908):687-93. 2002
82BDNF
Brain-derived neurotrophic factor: a novel human ovarian follicular protein.
Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF.
J Clin Endocrinol Metab 87(2):655-9. 2002
83BDNF
Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I.
Tabuchi A, Sakaya H, Kisukeda T, Fushiki H, Tsuda M.
J Biol Chem 277(39):35920-31. Epub 2002 Jul 11. 2002
84BDNF
Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus.
Solum DT, Handa RJ.
J Neurosci. 22(7):2650-9 2002
85BDNF, DRD3
BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization.
Guillin O, Diaz J, Carroll P, Griffon N, Schwartz JC, Sokoloff P.
Nature 411(6833):86-9. 2001
86BDNF
Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus.
Muller D, Djebbara-Hannas Z, Jourdain P, Vutskits L, Durbec P, Rougon G, Kiss JZ.
Proc Natl Acad Sci U S A. 97(8):4315-20. 2000
87BDNF, MBTPS1, PCSK1
Mammalian subtilisin/kexin isozyme SKI-1 : a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.
Seidah NG, et al.
Proc Natl Acad Sci U S A 96 : 1321-1326. 1999
88BDNF
Detailed transcript map of a 810-kb region at 11p14 involving identification of 10 novel human 3' exons.
Guillemot F, et al.
Eur J Hum Genet 7(4):487-95. 1999
89BDNF, NTF3
Patterned expression of BDNF and NT-3 in the retina and anterior segment of the developing mammalian eye.
Bennett JL, Zeiler SR, Jones KR.
Invest Ophthalmol Vis Sci 40(12):2996-3005 1999
90BDNF
Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.
Klöcker N, Kermer P, Gleichmann M, Weller M, Bähr M.
J Neurosci. 19(19):8517-27. 1999
91BDNF
BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.
Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S.
Cell. 98(6):739-55. 1999
92BDNF
Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities.
Lyons WE, Mamounas LA, Ricaurte GA, Coppola V, Reid SW, Bora SH, Wihler C, Koliatsos VE, Tessarollo L.
Proc Natl Acad Sci U S A. 96(26):15239-44. 1999
93BDNF
Haniu M, Montestruque S, Bures EJ, Talvenheimo J, Toso R, Lewis-Sandy S, Welcher AA, Rohde MF.
Interactions between brain-derived neurotrophic factor and the TRKB receptor. Identification of two ligand binding domains in soluble TRKB by affinity separation and chemical cross-linking.
J Biol Chem. 272(40):25296-303. 1997
94BDNF, FSHB, GTF2H1, MYOD1, WAGR
A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11 : distal p13 to proximal p15.1.
Fantes JA, et al.
Genomics 25 : 447-461. 1995
95BDNF, WAGR
A 1.7-Mb YAC contig around the human BDNF gene (11p13) : integration of the physical, genetic, and cytogenetic maps in relation to WAGR syndrome.
Rosier MF, et al.
Genomics 24 : 69-77. 1994
96BDNF
Formation of heterodimers from three neurotrophins, nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor.
Arakawa T, Haniu M, Narhi LO, Miller JA, Talvenheimo J, Philo JS, Chute HT, Matheson C, Carnahan J, Louis JC, et al.
J Biol Chem. 269(45):27833-9. 1994
97BDNF
The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.
Hanson IM, et al.
Genomics 13 : 1331-1333. 1992
98BDNF
Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF).
Pršschel M, et al.
Hum Mol Genet 1 : 353. 1992
99NTF3, BDNF
Human and rat brain-derived neurotrophic factor and neurotrophin-3 : gene structures, distributions, and chromosomal localizations.
Maisonpierre PC, et al.
Genomics 10 : 558-568. 1991
100NTF3, BDNF
Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse.
…zelik T, et al.
Genomics 10 : 569-575. 1991
101BDNF
Molecular cloning of a human gene that is a member of the nerve growth factor family.
Jones KR, Reichardt LF.
Proc Natl Acad Sci U S A. 87(20):8060-4. 1990