| 1 | ACTL6B, BDNF
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| BDNF rescues BAF53b-dependent synaptic plasticity and cocaine-associated memory in the nucleus accumbens.
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| White AO, Kramár EA, López AJ, Kwapis JL, Doan J, Saldana D, Davatolhagh MF, Alaghband Y, Blurton-Jones M, Matheos DP, Wood MA.
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| Nat Commun 7:11725. doi: 10.1038/ncomms11725.
2016
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| 2 | BDNF, LRIG1, NTRK2
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| Lrig1 is a cell-intrinsic modulator of hippocampal dendrite complexity and BDNF signaling.
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| Alsina FC, Hita FJ, Fontanet PA, Irala D, Hedman H, Ledda F, Paratcha G.
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| EMBO Rep 17(4):601-16. doi: 10.15252/embr.201541218. Epub 2016 Mar 2.
2016
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| 3 | BDNF, CYFIP1, EIF4E, MKNK1
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| BDNF stimulation of protein synthesis in cortical neurons requires the MAP kinase-interacting kinase MNK1.
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| Genheden M, Kenney JW, Johnston HE, Manousopoulou A, Garbis SD, Proud CG.
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| J Neurosci 35(3):972-84. doi: 10.1523/JNEUROSCI.2641-14.2015.
2015
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| 4 | BDNF, ELAVL4
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| HuD interacts with Bdnf mRNA and is essential for activity-induced BDNF synthesis in dendrites.
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| Vanevski F, Xu B.
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| PLoS One 10(2):e0117264. doi: 10.1371/journal.pone.0117264. eCollection 2015.
2015
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| 5 | BDNF, NTRK2, SLC6A5, SLC6A9
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| BDNF, via truncated TrkB receptor, modulates GlyT1 and GlyT2 in astrocytes.
|
| Aroeira RI, Sebastião AM, Valente CA.
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| Glia 63(12):2181-97. doi: 10.1002/glia.22884.
2015
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| 6 | BDNF, CRP
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| Protective Effects of BDNF against C-Reactive Protein-Induced Inflammation in Women.
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| Noren Hooten N, Ejiogu N, Zonderman AB, Evans MK.
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| Mediators Inflamm 2015:516783. doi: 10.1155/2015/516783. Epub 2015 May 26.
2015
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| 7 | BBS4, BDNF, NTRK2
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| BBS4 Is Necessary for Ciliary Localization of TrkB Receptor and Activation by BDNF.
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| Leitch CC, Zaghloul NA.
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| PLoS One 9(5):e98687. doi: 10.1371/journal.pone.0098687. eCollection 2014.
2014
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| 8 | BDNF, NTF3
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| Neurotrophin-3 regulates ribbon synapse density in the cochlea and induces synapse regeneration after acoustic trauma.
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| Wan G, Gómez-Casati ME, Gigliello AR, Liberman MC, Corfas G.
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| Elife 3. doi: 10.7554/eLife.03564.
2014
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| 9 | BDNF, NTF3
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| Effects of the neurotrophic factors BDNF, NT-3, and FGF2 on dissociated neurons of the cochlear nucleus.
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| Rak K, Völker J, Frenz S, Scherzad A, Schendzielorz P, Radeloff A, Jablonka S, Hagen R, Mlynski R.
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| Neuroreport 25(12):960-4. doi: 10.1097/WNR.0000000000000220.
2014
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| 10 | AICDA, BDNF
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| Activation-induced cytidine deaminase regulates activity-dependent BDNF expression in post-mitotic cortical neurons.
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| Ratnu VS, Wei W, Bredy TW.
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| Eur J Neurosci 40(7):3032-9. doi: 10.1111/ejn.12678.
2014
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| 11 | BDNF, ELP4
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| Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.
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| Gkampeta A, Fidani L, Clarimón J, Kalinderi K, Katopodi T, Zafeiriou D, Pavlou E.
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| Epilepsy Res 108(10):1734-9. doi: 10.1016/j.eplepsyres.2014.09.005.
2014
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| 12 | BDNF, DEL2P25, SIM1, TRKB
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| Obesity with associated developmental delay and/or learning disability in patients exhibiting additional features: Report of novel pathogenic copy number variants.
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| D'Angelo CS, Kohl I, Varela MC, de Castro CI, Kim CA, Bertola DR, Lourenço CM, Perez AB, Koiffmann CP.
|
| Am J Med Genet A 161(3):479-86. doi: 10.1002/ajmg.a.35761. Epub 2013 Feb 7.
2013
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| 13 | BDNF, ERBB2, NRG1
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| RET and NRG1 interplay in Hirschsprung disease.
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| Gui H, Tang WK, So MT, Proitsi P, Sham PC, Tam PK, Sau-Wai Ngan E, Cherny SS, Garcia-Barceló MM.
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| Hum Genet 132(5):591-600. doi: 10.1007/s00439-013-1272-9. Epub 2013 Feb 12.
2013
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| 14 | BDNF, SIK1
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| Role of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNF.
|
| Finsterwald C, Carrard A, Martin JL.
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| PLoS One 8(1):e54545. doi: 10.1371/journal.pone.0054545. Epub 2013 Jan 22.
2013
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| 15 | BDNF, ELAVL4
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| HuD promotes BDNF expression in brain neurons via selective stabilization of the BDNF long 3'UTR mRNA.
|
| Allen M, Bird C, Feng W, Liu G, Li W, Perrone-Bizzozero NI, Feng Y.
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| PLoS One 8(1):e55718. doi: 10.1371/journal.pone.0055718. Epub 2013 Jan 31.
2013
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| 16 | BDNF, CREB1, NR4A2
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| Nurr1 protein is required for N-methyl-D-aspartic acid (NMDA) receptor-mediated neuronal survival.
|
| Barneda-Zahonero B, Servitja JM, Badiola N, Miñano-Molina AJ, Fadó R, Saura CA, Rodríguez-Alvarez J.
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| J Biol Chem 287(14):11351-62. doi: 10.1074/jbc.M111.272427. Epub 2012 Jan 31.
2012
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| 17 | BDNF, NTRK2
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| Expression of TrkB and BDNF is associated with poor prognosis in non-small cell lung cancer.
|
| Okamura K, Harada T, Wang S, Ijichi K, Furuyama K, Koga T, Okamoto T, Takayama K, Yano T, Nakanishi Y.
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| Lung Cancer 78(1):100-6. doi: 10.1016/j.lungcan.2012.07.011. Epub 2012 Aug 18.
2012
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| 18 | BDNF, MMP9
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| Decreased serum levels of mature brain-derived neurotrophic factor (BDNF), but not its precursor proBDNF, in patients with major depressive disorder.
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| Yoshida T, Ishikawa M, Niitsu T, Nakazato M, Watanabe H, Shiraishi T, Shiina A, Hashimoto T, Kanahara N, Hasegawa T, Enohara M, Kimura A, Iyo M, Hashimoto K.
|
| PLoS One 7(8):e42676. doi: 10.1371/journal.pone.0042676. Epub 2012 Aug 3.
2012
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| 19 | BDNF
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| Brain-derived neurotrophic factor in primary headaches.
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| Fischer M, Wille G, Klien S, Shanib H, Holle D, Gaul C, Broessner G.
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| J Headache Pain 13(6):469-75. doi: 10.1007/s10194-012-0454-5. Epub 2012 May 15.
2012
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| 20 | BDNF
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| Plasma BDNF is associated with age-related white matter atrophy but not with cognitive function in older, non-demented adults.
|
| Driscoll I, Martin B, An Y, Maudsley S, Ferrucci L, Mattson MP, Resnick SM.
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| PLoS One 7(4):e35217. doi: 10.1371/journal.pone.0035217. Epub 2012 Apr 16.
2012
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| 21 | BDNF
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| Cooperative roles of BDNF expression in neurons and Schwann cells are modulated by exercise to facilitate nerve regeneration.
|
| Wilhelm JC, Xu M, Cucoranu D, Chmielewski S, Holmes T, Lau KS, Bassell GJ, English AW.
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| J Neurosci 32(14):5002-9. doi: 10.1523/JNEUROSCI.1411-11.2012.
2012
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| 22 | BDNF, COMT
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| Interaction of BDNF and COMT polymorphisms on paired-associative stimulation-induced cortical plasticity.
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| Witte AV, Kürten J, Jansen S, Schirmacher A, Brand E, Sommer J, Flöel A.
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| J Neurosci 32(13):4553-61. doi: 10.1523/JNEUROSCI.6010-11.2012.
2012
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| 23 | BDNF, RACK1, YWHAZ
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| Direct interaction between scaffolding proteins RACK1 and 14-3-3ζ regulates brain-derived neurotrophic factor (BDNF) transcription.
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| Neasta J, Kiely PA, He DY, Adams DR, O'Connor R, Ron D.
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| J Biol Chem 287(1):322-36. doi: 10.1074/jbc.M111.272195. Epub 2011 Nov 8. 2012
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| 24 | BDNF, NTRK2
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| Expression of brain-derived neurotrophic factor and TrkB receptor in the sudden infant death syndrome brainstem.
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| Tang S, Machaalani R, Waters KA.
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| Respir Physiol Neurobiol 180(1):25-33. doi: 10.1016/j.resp.2011.10.004. Epub 2011 Oct 14.
2012
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| 25 | BDNF, DEL16P112D, DEL16P112P, SIM1, TRKB
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| Copy number variants in obesity-related syndromes: review and perspectives on novel molecular approaches.
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| D'Angelo CS, Koiffmann CP.
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| J Obes 2012:845480. doi: 10.1155/2012/845480. Epub 2012 Dec 17.
2012
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| 26 | BDNF, SOD2
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| Brain-derived neurotrophic factor increases expression of MnSOD in human circulating angiogenic cells.
|
| He T, Katusic ZS.
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| Microvasc Res 83(3):366-71. doi: 10.1016/j.mvr.2012.01.001. Epub 2012 Jan 9.
2012
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| 27 | BDNF, PGRMC1
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| Progesterone increases the release of brain-derived neurotrophic factor from glia via progesterone receptor membrane component 1 (Pgrmc1)-dependent ERK5 signaling.
|
| Su C, Cunningham RL, Rybalchenko N, Singh M.
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| Endocrinology 153(9):4389-400. doi: 10.1210/en.2011-2177. Epub 2012 Jul 9.
2012
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| 28 | BDNF, PARD3, RAC1
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| Brain-derived neurotrophic factor (BDNF) induces polarized signaling of small GTPase (Rac1) protein at the onset of Schwann cell myelination through partitioning-defective 3 (Par3) protein.
|
| Tep C, Kim ML, Opincariu LI, Limpert AS, Chan JR, Appel B, Carter BD, Yoon SO.
|
| J Biol Chem 287(2):1600-8. doi: 10.1074/jbc.M111.312736. Epub 2011 Nov 29.
2012
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| 29 | BDNF, NFATC4
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| Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus.
|
| Quadrato G, Benevento M, Alber S, Jacob C, Floriddia EM, Nguyen T, Elnaggar MY, Pedroarena CM, Molkentin JD, Di Giovanni S.
|
| Proc Natl Acad Sci U S A 109(23):E1499-508. doi: 10.1073/pnas.1202068109. Epub 2012 May 14.
2012
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| 30 | BDNF
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| BDNF is a negative modulator of morphine action.
|
| Koo JW, Mazei-Robison MS, Chaudhury D, Juarez B, LaPlant Q, Ferguson D, Feng J, Sun H, Scobie KN, Damez-Werno D, Crumiller M, Ohnishi YN, Ohnishi YH, Mouzon E, Dietz DM, Lobo MK, Neve RL, Russo SJ, Han MH, Nestler EJ.
|
| Science 338(6103):124-8. doi: 10.1126/science.1222265.
2012
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| 31 | BDNF, DEL11PO
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| 11p14.1 microdeletions associated with ADHD, autism, developmental delay, and obesity.
|
| Shinawi M, Sahoo T, Maranda B, Skinner SA, Skinner C, Chinault C, Zascavage R, Peters SU, Patel A, Stevenson RE, Beaudet AL.
|
| Am J Med Genet A 155(6):1272-80. doi: 10.1002/ajmg.a.33878. Epub 2011 May 12.
2011
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| 32 | BDNF, GDNF, S100B
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| S100B protein, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor in human milk.
|
| Li R, Xia W, Zhang Z, Wu K.
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| PLoS One 6(6):e21663. Epub 2011 Jun 27.
2011
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| 33 | BDNF
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| Evidence of associations between bipolar disorder and the brain-derived neurotrophic factor (BDNF) gene.
|
| Sears C, Markie D, Olds R, Fitches A.
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| Bipolar Disord 13(7-8):630-7. doi: 10.1111/j.1399-5618.2011.00955.x.
2011
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| 34 | BDNF, NTRK2
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| Self-amplifying autocrine actions of BDNF in axon development.
|
| Cheng PL, Song AH, Wong YH, Wang S, Zhang X, Poo MM.
|
| Proc Natl Acad Sci U S A 108(45):18430-5. doi: 10.1073/pnas.1115907108. Epub 2011 Oct 24.
2011
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| 35 | BDNF, NTRK2
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| Expression of TrkB and BDNF in human cochlea-an immunohistochemical study.
|
| Liu W, Kinnefors A, Boström M, Rask-Andersen H.
|
| Cell Tissue Res 345(2):213-21. doi: 10.1007/s00441-011-1209-3. Epub 2011 Jul 8.
2011
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| 36 | BDNF
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| Identification of cis-elements and transcription factors regulating neuronal activity-dependent transcription of human BDNF gene.
|
| Pruunsild P, Sepp M, Orav E, Koppel I, Timmusk T.
|
| J Neurosci 31(9):3295-308. doi: 10.1523/JNEUROSCI.4540-10.2011.
2011
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| 37 | BDNF, NTRK2, SOD1
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| The in vivo contribution of motor neuron TrkB receptors to mutant SOD1 motor neuron disease.
|
| Zhai J, Zhou W, Li J, Hayworth CR, Zhang L, Misawa H, Klein R, Scherer SS, Balice-Gordon RJ, Kalb RG.
|
| Hum Mol Genet. 20(21):4116-31 2011
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| 38 | BDNF
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| Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging.
|
| Zeng Y, Tan M, Kohyama J, Sneddon M, Watson JB, Sun YE, Xie CW.
|
| J Neurosci 31(49):17800-10. doi: 10.1523/JNEUROSCI.3878-11.2011.
2011
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| 39 | BDNF, HAP1
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| Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release.
|
| Wu LL, Fan Y, Li S, Li XJ, Zhou XF.
|
| J Biol Chem 285(8):5614-23. Epub 2009 Dec 7.
2010
|
| 40 | BDNF
|
| BDNF variant Val66Met interacts with estrous cycle in the control of hippocampal function.
|
| Spencer JL, Waters EM, Milner TA, Lee FS, McEwen BS.
|
| Proc Natl Acad Sci U S A 107(9):4395-400. Epub 2010 Feb 8.PMID: 20142488 2010
|
| 41 | BDNF
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| Genetic variants in the BDNF gene and therapeutic response to risperidone in schizophrenia patients: a pharmacogenetic study.
|
| Xu M, Li S, Xing Q, Gao R, Feng G, Lin Z, St Clair D, He L.
|
| Eur J Hum Genet 18(6):707-12. Epub 2010 Jan 20.PMID: 20087404 2010
|
| 42 | BDNF, RAI1, SMS
|
| Rai1 haploinsufficiency causes reduced Bdnf expression resulting in hyperphagia, obesity and altered fat distribution in mice and humans with no evidence of metabolic syndrome.
|
| Burns B, Schmidt K, Williams SR, Kim S, Girirajan S, Elsea SH.
|
| Hum Mol Genet 19(20):4026-42. Epub 2010 Jul 27.PMID: 20663924 2010
|
| 43 | BDNF, NTRK2
|
| Immunolocalization of pro- and mature-brain derived neurotrophic factor (BDNF) and receptor TrkB in the human brainstem and hippocampus.
|
| Tang S, Machaalani R, Waters KA.
|
| Brain Res 1354:1-14. Epub 2010 Jul 29.PMID: 20673758 2010
|
| 44 | BDNF, NTRK2
|
| Increased BDNF levels and NTRK2 gene association suggest a disruption of BDNF/TrkB signaling in autism.
|
| Correia CT, Coutinho AM, Sequeira AF, Sousa IG, Lourenço Venda L, Almeida JP, Abreu RL, Lobo C, Miguel TS, Conroy J, Cochrane L, Gallagher L, Gill M, Ennis S, Oliveira GG, Vicente AM.
|
| Genes Brain Behav 9(7):841-8. doi: 10.1111/j.1601-183X.2010.00627.x. Epub 2010 Aug 19.PMID: 20662941 2010
|
| 45 | BDNF, EEF2, EEF2K
|
| Synaptic activity controls dendritic spine morphology by modulating eEF2-dependent BDNF synthesis.
|
| Verpelli C, Piccoli G, Zibetti C, Zanchi A, Gardoni F, Huang K, Brambilla D, Di Luca M, Battaglioli E, Sala C.
|
| J Neurosci 30(17):5830-42. doi: 10.1523/JNEUROSCI.0119-10.2010.
2010
|
| 46 | BDNF, FTO, HSPA1B, MC4R, TMEM18
|
| Genome-wide association yields new sequence variants at seven loci that associate with measures of obesity.
|
| Thorleifsson G, Walters GB, Gudbjartsson DF, Steinthorsdottir V, Sulem P, Helgadottir A, Styrkarsdottir U, Gretarsdottir S, Thorlacius S, Jonsdottir I, Jonsdottir T, Olafsdottir EJ, Olafsdottir GH, Jonsson T, Jonsson F, Borch-Johnsen K, Hansen T, Andersen G, Jorgensen T, Lauritzen T, Aben KK, Verbeek AL, Roeleveld N, Kampman E, Yanek LR, Becker LC, Tryggvadottir L, Rafnar T, Becker DM, Gulcher J, Kiemeney LA, Pedersen O, Kong A, Thorsteinsdottir U, Stefansson K.
|
| Nat Genet 41(1):18-24. Epub 2008 Dec 14. 2009
|
| 47 | BDNF, REST
|
| Remote control of activity-dependent BDNF gene promoter-I transcription mediated by REST/NRSF.
|
| Hara D, Fukuchi M, Miyashita T, Tabuchi A, Takasaki I, Naruse Y, Mori N, Kondo T, Tsuda M.
|
| Biochem Biophys Res Commun 384(4):506-11. Epub 2009 May 6.
2009
|
| 48 | BDNF, FAIM2, GNPDA2, MC4R, SEC16B, TMEM18
|
| Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
|
| Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Kamatani N, Nakamura Y.
|
| J Hum Genet 54(12):727-31. Epub 2009 Oct 23.
2009
|
| 49 | BDNF
|
| Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease.
|
| Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, Chiba AA, Tuszynski MH.
|
| Nat Med. 15(3):331-7 2009
|
| 50 | BDNF
|
| New insights into brain BDNF function in normal aging and Alzheimer disease.
|
| Tapia-Arancibia L, Aliaga E, Silhol M, Arancibia S.
|
| Brain Res Rev rain Res Rev. 2008 Aug 3. [Epub ahead of print]
2008
|
| 51 | BDNF, WAGR, WAGRO
|
| Brain-derived neurotrophic factor and obesity in the WAGR syndrome.
|
| Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL, Uhl GR, Rennert OM, Yanovski JA.
|
| N Engl J Med 359(9):918-27. Erratum in: N Engl J Med. 2008 Sep 25;359(13):1414. 2008
|
| 52 | BDNF, HD
|
| Systematic assessment of BDNF and its receptor levels in human cortices affected by Huntington's disease.
|
| Zuccato C, Marullo M, Conforti P, MacDonald ME, Tartari M, Cattaneo E.
|
| Brain Pathol 18(2):225-38. Epub 2007 Dec 17.
2008
|
| 53 | BDNF, HD, HTT
|
| Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons.
|
| Zala D, Colin E, Rangone H, Liot G, Humbert S, Saudou F.
|
| Hum Mol Genet 17(24):3837-46. Epub 2008 Sep 4. 2008
|
| 54 | AREG, ARHGAP, BDNF, EPHA4, GFPT2, GRIA3, NEFM, PENK, PMCH, SLC16A6, SYT1
|
| Gene expression pattern of functional neuronal cells derived from human bone marrow mesenchymal stromal cells.
|
| Tondreau T, Dejeneffe M, Meuleman N, Stamatopoulos B, Delforge A, Martiat P, Bron D, Lagneaux L.
|
| BMC Genomics 9:166.PMID: 18405367 2008
|
| 55 | BDNF, NTRK2
|
| Retinal TrkB receptors regulate neural development in the inner, but not outer, retina.
|
| Grishanin RN, Yang H, Liu X, Donohue-Rolfe K, Nune GC, Zang K, Xu B, Duncan JL, Lavail MM, Copenhagen DR, Reichardt LF.
|
| Mol Cell Neurosci 38(3):431-43. Epub 2008 Apr 22.
2008
|
| 56 | BDNF
|
| BDNF is essential to promote persistence of long-term memory storage.
|
| Bekinschtein P, Cammarota M, Katche C, Slipczuk L, Rossato JI, Goldin A, Izquierdo I, Medina JH.
|
| Proc Natl Acad Sci U S A. 105(7):2711-6. 2008
|
| 57 | BDNF
|
| Genetic variants in brain-derived neurotrophic factor associated with Alzheimer's disease.
|
| Huang R, Huang J, Cathcart H, Smith S, Poduslo SE.
|
| J Med Genet 44(2):e66.
2007
|
| 58 | BDNF
|
| Brain-derived neurotrophic factor and risk of schizophrenia: an association study and meta-analysis.
|
| Qian L, Zhao J, Shi Y, Zhao X, Feng G, Xu F, Zhu S, He L.
|
| Biochem Biophys Res Commun 353(3):738-43. Epub 2006 Dec 22. 2007
|
| 59 | BDNF, SPRY2
|
| Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival.
|
| Gross I, Armant O, Benosman S, de Aguilar JL, Freund JN, Kedinger M, Licht JD, Gaiddon C, Loeffler JP.
|
| Cell Death Differ 14(10):1802-12. Epub 2007 Jun 29. 2007
|
| 60 | BDNF, BDNFOS
|
| Dissecting the human BDNF locus: bidirectional transcription, complex splicing, and multiple promoters.
|
| Pruunsild P, Kazantseva A, Aid T, Palm K, Timmusk T.
|
| Genomics 90(3):397-406. Epub 2007 Jul 12. 2007
|
| 61 | BDNF
|
| Association study of the brain-derived neurotropic factor (BDNF) gene in attention deficit hyperactivity disorder.
|
| Lee J, Laurin N, Crosbie J, Ickowicz A, Pathare T, Malone M, Tannock R, Kennedy JL, Schachar R, Barr CL.
|
| Am J Med Genet B Neuropsychiatr Genet 144(8):976-81. 2007
|
| 62 | BDNF
|
| The Val66Met polymorphism of the brain-derived neurotrophic factor gene is associated with risk for psychosis: evidence from a family-based association study.
|
| Rosa A, Cuesta MJ, Fatjo-Vilas M, Peralta V, Zarzuela A, Fananas L.
|
| Am J Med Genet B Neuropsychiatr Genet 141(2):135-8. 2006
|
| 63 | BDNF
|
| Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior.
|
| Chen ZY, Jing D, Bath KG, Ieraci A, Khan T, Siao CJ, Herrera DG, Toth M, Yang C, McEwen BS, Hempstead BL, Lee FS.
|
| Science 314(5796):140-3. 2006
|
| 64 | BDNF
|
| Hyperphagia, severe obesity, impaired cognitive function, and hyperactivity associated with functional loss of one copy of the brain-derived neurotrophic factor (BDNF) gene.
|
| Gray J, Yeo GS, Cox JJ, Morton J, Adlam AL, Keogh JM, Yanovski JA, El Gharbawy A, Han JC, Tung YC, Hodges JR, Raymond FL, O'rahilly S, Farooqi IS.
|
| Diabetes 55(12):3366-71.
2006
|
| 65 | BDNF
|
| Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
|
| Berton O, McClung CA, Dileone RJ, Krishnan V, Renthal W, Russo SJ, Graham D, Tsankova NM, Bolanos CA, Rios M, Monteggia LM, Self DW, Nestler EJ.
|
| Science. 311(5762):864-8. 2006
|
| 66 | BDNF
|
| Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor.
|
| Li Y, Jia YC, Cui K, Li N, Zheng ZY, Wang YZ, Yuan XB.
|
| Nature 434(7035):894-8. Epub 2005 Mar 9. 2005
|
| 67 | BDNF
|
| BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain.
|
| Coull JA, Beggs S, Boudreau D, Boivin D, Tsuda M, Inoue K, Gravel C, Salter MW, De Koninck Y.
|
| Nature 438(7070):1017-21. 2005
|
| 68 | BDNF, CCHS3
|
| Neurotrophic factor expression in three infants with Ondine's curse.
|
| Chiaretti A, Zorzi G, Di Rocco C, Genovese O, Antonelli A, Piastra M, Polidori G, Aloe L.
|
| Pediatr Neurol 33(5):331-6.
2005
|
| 69 | BDNF
|
| Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.
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| Chen ZY, Ieraci A, Teng H, Dall H, Meng CX, Herrera DG, Nykjaer A, Hempstead BL, Lee FS.
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| J Neurosci. 25(26):6156-66. 2005
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| 70 | BDNF
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| Association of BDNF with anorexia, bulimia and age of onset of weight loss in six European populations.
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| Ribases M, Gratacos M, Fernandez-Aranda F, Bellodi L, Boni C, Anderluh M, Cavallini MC, Cellini E, Di Bella D, Erzegovesi S, Foulon C, Gabrovsek M, Gorwood P, Hebebrand J, Hinney A, Holliday J, Hu X, Karwautz A, Kipman A, Komel R, Nacmias B, Remschmidt H, Ricca V, Sorbi S, Wagner G, Treasure J, Collier DA, Estivill X.
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| Hum Mol Genet 13(12):1205-12. Epub 2004 Apr 28. 2004
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| 71 | BDNF, HTT, HAP1, DCTN1
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| Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
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| Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F.
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| Cell 118(1):127-38. 2004
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| 72 | BDNF, HD
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| Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.
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| Canals JM, Pineda JR, Torres-Peraza JF, Bosch M, Martín-Ibañez R, Muñoz MT, Mengod G, Ernfors P, Alberch J.
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| J Neurosci 24(35):7727-39.
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| 73 | BDNF, CFL1
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| Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin.
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| Gehler S, Shaw AE, Sarmiere PD, Bamburg JR, Letourneau PC.
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| J Neurosci 24(47):10741-9. 2004
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| 74 | BDNF
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| The secretory granule-associated protein CAPS2 regulates neurotrophin release and cell survival.
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| Sadakata T, Mizoguchi A, Sato Y, Katoh-Semba R, Fukuda M, Mikoshiba K, Furuichi T.
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| J Neurosci. 24(1):43-52. 2004
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| 75 | BDNF
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| The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function.
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| Egan MF, Kojima M, Callicott JH, Goldberg TE, Kolachana BS, Bertolino A, Zaitsev E, Gold B, Goldman D, Dean M, Lu B, Weinberger DR.
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| Cell 112(2):257-69. 2003
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| 76 | BDNF
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| Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder.
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| Hall D, Dhilla A, Charalambous A, Gogos JA, Karayiorgou M.
|
| Am J Hum Genet 73(2):370-6. Epub 2003 Jun 27. 2003
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| 77 | BDNF
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| Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson's disease and age of onset.
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| Hong CJ, Liu HC, Liu TY, Lin CH, Cheng CY, Tsai SJ.
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| Neurosci Lett 353(1):75-7. 2003
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| 78 | BDNF
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| The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study.
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| Neves-Pereira M, Mundo E, Muglia P, King N, Macciardi F, Kennedy JL.
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| Am J Hum Genet 71(3):651-5. 2002
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| 79 | BDNF, NTF4, NTRK2
|
| A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4.
|
| Naylor RL, Robertson AG, Allen SJ, Sessions RB, Clarke AR, Mason GG, Burston JJ, Tyler SJ, Wilcock GK, Dawbarn D.
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| Biochem Biophys Res Commun 291(3):501-7. 2002
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| 80 | BDNF, NTRK2, NTRK3
|
| Distinct requirements for TrkB and TrkC signaling in target innervation by sensory neurons.
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| Postigo A, Calella AM, Fritzsch B, Knipper M, Katz D, Eilers A, Schimmang T, Lewin GR, Klein R, Minichiello L.
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| Genes Dev 16(5):633-45. 2002
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| 81 | BDNF, NTRK2, SCN11A
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| Neurotrophin-evoked depolarization requires the sodium channel Na(V)1.9.
|
| Blum R, Kafitz KW, Konnerth A.
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| Nature 419(6908):687-93. 2002
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| 82 | BDNF
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| Brain-derived neurotrophic factor: a novel human ovarian follicular protein.
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| Seifer DB, Feng B, Shelden RM, Chen S, Dreyfus CF.
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| J Clin Endocrinol Metab 87(2):655-9. 2002
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| 83 | BDNF
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| Involvement of an upstream stimulatory factor as well as cAMP-responsive element-binding protein in the activation of brain-derived neurotrophic factor gene promoter I.
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| Tabuchi A, Sakaya H, Kisukeda T, Fushiki H, Tsuda M.
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| J Biol Chem 277(39):35920-31. Epub 2002 Jul 11. 2002
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| 84 | BDNF
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| Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus.
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| Solum DT, Handa RJ.
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| J Neurosci. 22(7):2650-9 2002
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| 85 | BDNF, DRD3
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| BDNF controls dopamine D3 receptor expression and triggers behavioural sensitization.
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| Guillin O, Diaz J, Carroll P, Griffon N, Schwartz JC, Sokoloff P.
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| Nature 411(6833):86-9. 2001
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| 86 | BDNF
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| Brain-derived neurotrophic factor restores long-term potentiation in polysialic acid-neural cell adhesion molecule-deficient hippocampus.
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| Muller D, Djebbara-Hannas Z, Jourdain P, Vutskits L, Durbec P, Rougon G, Kiss JZ.
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| Proc Natl Acad Sci U S A. 97(8):4315-20. 2000
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| 87 | BDNF, MBTPS1, PCSK1
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| Mammalian subtilisin/kexin isozyme SKI-1 : a widely expressed proprotein convertase with a unique cleavage specificity and cellular localization.
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| Seidah NG, et al.
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| Proc Natl Acad Sci U S A 96 : 1321-1326. 1999
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| 88 | BDNF
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| Detailed transcript map of a 810-kb region at 11p14 involving identification of 10 novel human 3' exons.
|
| Guillemot F, et al.
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| Eur J Hum Genet 7(4):487-95. 1999
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| 89 | BDNF, NTF3
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| Patterned expression of BDNF and NT-3 in the retina and anterior segment of the developing mammalian eye.
|
| Bennett JL, Zeiler SR, Jones KR.
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| Invest Ophthalmol Vis Sci 40(12):2996-3005 1999
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| 90 | BDNF
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| Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.
|
| Klöcker N, Kermer P, Gleichmann M, Weller M, Bähr M.
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| J Neurosci. 19(19):8517-27. 1999
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| 91 | BDNF
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| BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex.
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| Huang ZJ, Kirkwood A, Pizzorusso T, Porciatti V, Morales B, Bear MF, Maffei L, Tonegawa S.
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| Cell. 98(6):739-55. 1999
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| 92 | BDNF
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| Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities.
|
| Lyons WE, Mamounas LA, Ricaurte GA, Coppola V, Reid SW, Bora SH, Wihler C, Koliatsos VE, Tessarollo L.
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| Proc Natl Acad Sci U S A. 96(26):15239-44. 1999
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| 93 | BDNF
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| Haniu M, Montestruque S, Bures EJ, Talvenheimo J, Toso R, Lewis-Sandy S, Welcher AA, Rohde MF.
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| Interactions between brain-derived neurotrophic factor and the TRKB receptor. Identification of two ligand binding domains in soluble TRKB by affinity separation and chemical cross-linking.
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| J Biol Chem. 272(40):25296-303. 1997
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| 94 | BDNF, FSHB, GTF2H1, MYOD1, WAGR
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| A high-resolution integrated physical, cytogenetic, and genetic map of human chromosome 11 : distal p13 to proximal p15.1.
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| Fantes JA, et al.
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| Genomics 25 : 447-461. 1995
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| 95 | BDNF, WAGR
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| A 1.7-Mb YAC contig around the human BDNF gene (11p13) : integration of the physical, genetic, and cytogenetic maps in relation to WAGR syndrome.
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| Rosier MF, et al.
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| Genomics 24 : 69-77. 1994
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| 96 | BDNF
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| Formation of heterodimers from three neurotrophins, nerve growth factor, neurotrophin-3, and brain-derived neurotrophic factor.
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| Arakawa T, Haniu M, Narhi LO, Miller JA, Talvenheimo J, Philo JS, Chute HT, Matheson C, Carnahan J, Louis JC, et al.
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| J Biol Chem. 269(45):27833-9. 1994
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| 97 | BDNF
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| The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13-p14.
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| Hanson IM, et al.
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| Genomics 13 : 1331-1333. 1992
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| 98 | BDNF
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| Dinucleotide repeat polymorphism at the human gene for the brain-derived neurotrophic factor (BDNF).
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| Pršschel M, et al.
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| Hum Mol Genet 1 : 353. 1992
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| 99 | NTF3, BDNF
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| Human and rat brain-derived neurotrophic factor and neurotrophin-3 : gene structures, distributions, and chromosomal localizations.
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| Maisonpierre PC, et al.
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| Genomics 10 : 558-568. 1991
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| 100 | NTF3, BDNF
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| Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse.
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| …zelik T, et al.
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| Genomics 10 : 569-575. 1991
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| 101 | BDNF
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| Molecular cloning of a human gene that is a member of the nerve growth factor family.
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