1 | BCL11B, TCF3
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| Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network.
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| Longabaugh WJR, Zeng W, Zhang JA, Hosokawa H, Jansen CS, Li L, Romero-Wolf M, Liu P, Kueh HY, Mortazavi A, Rothenberg EV.
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| Proc Natl Acad Sci U S A 114(23):5800-5807. doi: 10.1073/pnas.1610617114.
2017
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2 | BCL11B
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| The T-ALL related gene BCL11B regulates the initial stages of human T-cell differentiation.
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| Ha VL, Luong A, Li F, Casero D, Malvar J, Kim YM, Bhatia R, Crooks GM, Parekh C.
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| Leukemia eukemia. 2017 Mar 14. doi: 10.1038/leu.2017.70. [Epub ahead of print]
2017
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3 | BCL11B
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| A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland.
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| Cai S, Kalisky T, Sahoo D, Dalerba P, Feng W, Lin Y, Qian D, Kong A, Yu J, Wang F, Chen EY, Scheeren FA, Kuo AH, Sikandar SS, Hisamori S, van Weele LJ, Heiser D, Sim S, Lam J, Quake S, Clarke MF.
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| Cell Stem Cell 20(2):247-260.e5. doi: 10.1016/j.stem.2016.11.007. Epub 2016 Dec 29.
2017
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4 | BCL11B, MSX2
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| Bcl11b regulates enamel matrix protein expression and dental epithelial cell differentiation during rat tooth development.
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| Li Z, Chen G, Yang Y, Guo W, Tian W.
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| Mol Med Rep 15(1):297-304. doi: 10.3892/mmr.2016.6030. Epub 2016 Dec 12.
2017
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5 | BCL11B, IMD49
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| Multisystem Anomalies in Severe Combined Immunodeficiency with Mutant BCL11B.
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| Punwani D, Zhang Y, Yu J, Cowan MJ, Rana S, Kwan A, Adhikari AN, Lizama CO, Mendelsohn BA, Fahl SP, Chellappan A, Srinivasan R, Brenner SE, Wiest DL, Puck JM.
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| N Engl J Med 375(22):2165-2176.
2016
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6 | BCL11B
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| Structure-function integrity of the adult hippocampus depends on the transcription factor Bcl11b/Ctip2.
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| Simon R, Baumann L, Fischer J, Seigfried FA, De Bruyckere E, Liu P, Jenkins NA, Copeland NG, Schwegler H, Britsch S.
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| Genes Brain Behav 15(4):405-19. doi: 10.1111/gbb.12287. Epub 2016 Mar 30.
2016
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7 | BCL11B
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| Transcription Factor Bcl11b Controls Identity and Function of Mature Type 2 Innate Lymphoid Cells.
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| Califano D, Cho JJ, Uddin MN, Lorentsen KJ, Yang Q, Bhandoola A, Li H, Avram D.
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| Immunity 43(2):354-68. doi: 10.1016/j.immuni.2015.07.005. Epub 2015 Jul 28.
2015
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8 | BCL11B
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| Bcl11b is essential for group 2 innate lymphoid cell development.
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| Walker JA, Oliphant CJ, Englezakis A, Yu Y, Clare S, Rodewald HR, Belz G, Liu P, Fallon PG, McKenzie AN.
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| J Exp Med 212(6):875-82. doi: 10.1084/jem.20142224. Epub 2015 May 11.
2015
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9 | BCL11B
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| The multifaceted roles of Bcl11b in thymic and peripheral T cells: impact on immune diseases.
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| Avram D, Califano D.
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| J Immunol 193(5):2059-65. doi: 10.4049/jimmunol.1400930. Review.
2014
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10 | BCL11B, SP6
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| Ctip2-mediated Sp6 transcriptional regulation in dental epithelium-derived cells.
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| Adiningrat A, Tanimura A, Miyoshi K, Yanuaryska RD, Hagita H, Horiguchi T, Noma T.
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| J Med Invest 61(1-2):126-36.
2014
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11 | BCL11B, CDK9
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| CTIP2 is a negative regulator of P-TEFb.
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| Cherrier T, Le Douce V, Eilebrecht S, Riclet R, Marban C, Dequiedt F, Goumon Y, Paillart JC, Mericskay M, Parlakian A, Bausero P, Abbas W, Herbein G, Kurdistani SK, Grana X, Van Driessche B, Schwartz C, Candolfi E, Benecke AG, Van Lint C, Rohr O.
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| Proc Natl Acad Sci U S A 110(31):12655-60. doi: 10.1073/pnas.1220136110. Epub 2013 Jul 12.
2013
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12 | BCL11B
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| A far downstream enhancer for murine Bcl11b controls its T-cell specific expression.
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| Li L, Zhang JA, Dose M, Kueh HY, Mosadeghi R, Gounari F, Rothenberg EV.
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| Blood 122(6):902-11. doi: 10.1182/blood-2012-08-447839. Epub 2013 Jun 5.
2013
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13 | BCL11B
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| Reduced level of the BCL11B protein is associated with adult T-cell leukemia/lymphoma.
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| Kurosawa N, Fujimoto R, Ozawa T, Itoyama T, Sadamori N, Isobe M.
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| PLoS One 8(1):e55147. doi: 10.1371/journal.pone.0055147. Epub 2013 Jan 30.
2013
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14 | BCL11B, IKZF2
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| HELIOS-BCL11B fusion gene involvement in a t(2;14)(q34;q32) in an adult T-cell leukemia patient.
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| Fujimoto R, Ozawa T, Itoyama T, Sadamori N, Kurosawa N, Isobe M.
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| Cancer Genet 205(7-8):356-64. doi: 10.1016/j.cancergen.2012.04.006.
2012
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15 | BCL11B
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| BCL11B suppression does not influence CD34(+) cell differentiation and proliferation.
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| Shen Q, Huang X, Chen S, Yang L, Chen S, Li B, Wu X, Grabarczyk P, Przybylski GK, Schmidt CA, Li Y.
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| Hematology 17(6):329-33. doi: 10.1179/1024533212Z.000000000145.
2012
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16 | BCL11B
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| Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling.
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| Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK.
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| J Cell Sci 125(Pt 23):5733-44. doi: 10.1242/jcs.108969. Epub 2012 Sep 26.
2012
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17 | BCL11B, DSP
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| A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.
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| Simon R, Brylka H, Schwegler H, Venkataramanappa S, Andratschke J, Wiegreffe C, Liu P, Fuchs E, Jenkins NA, Copeland NG, Birchmeier C, Britsch S.
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| EMBO J 31(13):2922-36. doi: 10.1038/emboj.2012.142. Epub 2012 May 15.
2012
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18 | BCL11B
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| The BCL11B tumor suppressor is mutated across the major molecular subtypes of T-cell acute lymphoblastic leukemia.
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| Gutierrez A, Kentsis A, Sanda T, Holmfeldt L, Chen SC, Zhang J, Protopopov A, Chin L, Dahlberg SE, Neuberg DS, Silverman LB, Winter SS, Hunger SP, Sallan SE, Zha S, Alt FW, Downing JR, Mullighan CG, Look AT.
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| Blood 118(15):4169-73. doi: 10.1182/blood-2010-11-318873. Epub 2011 Aug 30.
2011
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19 | BCL11B
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| An early T cell lineage commitment checkpoint dependent on the transcription factor Bcl11b.
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| Li L, Leid M, Rothenberg EV.
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| Science. 329(5987):89-93. 2010
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20 | BCL11B
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| An essential developmental checkpoint for production of the T cell lineage.
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| Ikawa T, Hirose S, Masuda K, Kakugawa K, Satoh R, Shibano-Satoh A, Kominami R, Katsura Y, Kawamoto H.
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| Science. 329(5987):93-6. 2010
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21 | BCL11B
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| Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis.
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| Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M.
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| Proc Natl Acad Sci U S A 106(11):4278-83. Epub 2009 Feb 26.
2009
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22 | BCL11B, MAP3K8
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| BCL11B enhances TCR/CD28-triggered NF-kappaB activation through up-regulation of Cot kinase gene expression in T-lymphocytes.
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| Cismasiu VB, Duque J, Paskaleva E, Califano D, Ghanta S, Young HA, Avram D.
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| Biochem J 417(2):457-66.
2009
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23 | BCL11B, CDKN1A, SUV39H1
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| p21(WAF1) gene promoter is epigenetically silenced by CTIP2 and SUV39H1.
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| Cherrier T, Suzanne S, Redel L, Calao M, Marban C, Samah B, Mukerjee R, Schwartz C, Gras G, Sawaya BE, Zeichner SL, Aunis D, Van Lint C, Rohr O.
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| Oncogene 28(38):3380-9. Epub 2009 Jul 6.PMID: 19581932 2009
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24 | BCL11B
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| BCL11B is a general transcriptional repressor of the HIV-1 long terminal repeat in T lymphocytes through recruitment of the NuRD complex.
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| Cismasiu VB, Paskaleva E, Suman Daya S, Canki M, Duus K, Avram D.
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| Virology 380(2):173-81. Epub 2008 Sep 2.
2008
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25 | BCL11B, FEZF2
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| The Fezf2-Ctip2 genetic pathway regulates the fate choice of subcortical projection neurons in the developing cerebral cortex.
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| Chen B, Wang SS, Hattox AM, Rayburn H, Nelson SB, McConnell SK.
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| Proc Natl Acad Sci U S A 105(32):11382-7. Epub 2008 Aug 4.
2008
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26 | BCL11B
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| Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells.
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| Grabarczyk P, Przybylski GK, Depke M, Völker U, Bahr J, Assmus K, Bröker BM, Walther R, Schmidt CA.
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| Oncogene 26(26):3797-810. Epub 2006 Dec 18.
2007
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27 | BCL11B
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| Lack of Bcl11b tumor suppressor results in vulnerability to DNA replication stress and damages.
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| Kamimura K, Mishima Y, Obata M, Endo T, Aoyagi Y, Kominami R.
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| Oncogene 26(40):5840-50. Epub 2007 Mar 19.
2007
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28 | BCL11B
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| Recruitment of chromatin-modifying enzymes by CTIP2 promotes HIV-1 transcriptional silencing.
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| Marban C, Suzanne S, Dequiedt F, de Walque S, Redel L, Van Lint C, Aunis D, Rohr O.
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| EMBO J. 26(2):412-23. 2007
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29 | BCL11B, CDKN1C
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| CTIP2 associates with the NuRD complex on the promoter of p57KIP2, a newly identified CTIP2 target gene.
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| Topark-Ngarm A, Golonzhka O, Peterson VJ, Barrett B Jr, Martinez B, Crofoot K, Filtz TM, Leid M.
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| J Biol Chem 281(43):32272-83. Epub 2006 Sep 1.
2006
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30 | BCL11B
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| BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes.
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| Cismasiu VB, Ghanta S, Duque J, Albu DI, Chen HM, Kasturi R, Avram D.
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| Blood. 108(8):2695-702. 2006
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31 | BCL11B, FEZF2
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| Fezl regulates the differentiation and axon targeting of layer 5 subcortical projection neurons in cerebral cortex.
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| Chen B, Schaevitz LR, McConnell SK.
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| Proc Natl Acad Sci U S A 102(47):17184-9. Epub 2005 Nov 11. 2005
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32 | BCL11B, TALL, TLX3
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| Activation of HOX11L2 by juxtaposition with 3'-BCL11B in an acute lymphoblastic leukemia cell line (HPB-ALL) with t(5;14)(q35;q32.2).
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| MacLeod RA, Nagel S, Kaufmann M, Janssen JW, Drexler HG.
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| Genes Chromosomes Cancer 37(1):84-91. 2003
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33 | BCL11B
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| Recruitment of Tat to heterochromatin protein HP1 via interaction with CTIP2 inhibits human immunodeficiency virus type 1 replication in microglial cells.
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| Rohr O, Lecestre D, Chasserot-Golaz S, Marban C, Avram D, Aunis D, Leid M, Schaeffer E.
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| J Virol. 77(9):5415-27. 2003
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34 | BCL11B
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| Bcl11b is required for differentiation and survival of alphabeta T lymphocytes.
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| Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, Mishima Y, Hitomi J, Yamamoto T, Utsuyama M, Niwa O, Aizawa S, Kominami R.
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| Nat Immunol. 4(6):533-9. 2003
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35 | BCL11B, BCL11A
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| The BCL11 gene family: involvement of BCL11A in lymphoid malignancies
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| Satterwhite E, Sonoki T, Willis TG, Harder L, Nowak R, Arriola EL, Liu H, Price HP, Gesk S, Steinemann D, Schlegelberger B, Oscier DG, Siebert R, Tucker PW, Dyer MJ.
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| Blood 98(12):3413-20. 2001
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