1 | BCAR1, CFLAR
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| The interaction of CFLAR with p130Cas promotes cell migration.
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| Li H, Li L, Qiu X, Zhang J, Hua Z.
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| Biochim Biophys Acta Mol Cell Res. Feb;1870(2):119390. doi: 10.1016/j.bbamcr.2022.119390. Epub 2022 Nov 16. 2023
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2 | BCAR1, EZR
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| Ezrin Is Associated with Disease Progression in Ovarian Carcinoma.
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| Horwitz V, Davidson B, Stern D, Tropé CG, Tavor Re'em T, Reich R.
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| PLoS One 11(9):e0162502. doi: 10.1371/journal.pone.0162502. eCollection 2016.
2016
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3 | BCAR1, WASL
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| N-WASP-directed actin polymerization activates Cas phosphorylation and lamellipodium spreading.
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| Zhang X, Moore SW, Iskratsch T, Sheetz MP.
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| J Cell Sci 127(Pt 7):1394-405. doi: 10.1242/jcs.134692. Epub 2014 Jan 30.
2014
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4 | BCAR1, MAPK7, PTK6
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| Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate.
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| Zheng Y, Asara JM, Tyner AL.
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| J Biol Chem 287(1):148-58. doi: 10.1074/jbc.M111.298117. Epub 2011 Nov 14.
2012
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5 | BCAR1, CASS4, NEDD9
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| NEDD9 and BCAR1 negatively regulate E-cadherin membrane localization, and promote E-cadherin degradation.
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| Tikhmyanova N, Golemis EA.
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| PLoS One 6(7):e22102. Epub 2011 Jul 12.
2011
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6 | BCAR1, NRP1
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| Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells.
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| Evans IM, Yamaji M, Britton G, Pellet-Many C, Lockie C, Zachary IC, Frankel P.
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| Mol Cell Biol 31(6):1174-85. Epub 2011 Jan 18.
2011
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7 | BCAR1, SYK
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| Identification of BCAR-1 as a new substrate of Syk tyrosine kinase through a determination of amino acid sequence preferences surrounding the substrate tyrosine residue.
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| Kim JY, Huh K, Jung R, Kim TJ.
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| Immunol Lett 135(1-2):151-7. Epub 2010 Oct 31.
2011
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8 | BCAR1, NRP1
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| Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.
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| Pellet-Many C, Frankel P, Evans IM, Herzog B, Jünemann-Ramírez M, Zachary IC.
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| Biochem J 435(3):609-18.
2011
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9 | BCAR1
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| Tyrosine phosphorylation within the SH3 domain regulates CAS subcellular localization, cell migration, and invasiveness.
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| Janotiak R, Tolde O, Brůhová Z, Novotný M, Hanks SK, Rösel D, Brábek J.
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| Mol Biol Cell 22(22):4256-67. doi: 10.1091/mbc.E11-03-0207. Epub 2011 Sep 21.
2011
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10 | BCAR1, BCAR3, SRC
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| BCAR3 regulates Src/p130 Cas association, Src kinase activity, and breast cancer adhesion signaling.
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| Schuh NR, Guerrero MS, Schrecengost RS, Bouton AH.
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| J Biol Chem 285(4):2309-17. Epub 2009 Nov 23.PMID: 19940159 2010
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11 | BCAR1, CASS4, EFS, NEDD9
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| CAS proteins in normal and pathological cell growth control.
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| Tikhmyanova N, Little JL, Golemis EA.
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| Cell Mol Life Sci 67(7):1025-48. Epub 2009 Nov 25. Review.
2010
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12 | BCAR1, CASS4, EFS, NEDD9
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| Dcas supports cell polarization and cell-cell adhesion complexes in development.
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| Tikhmyanova N, Tulin AV, Roegiers F, Golemis EA.
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| PLoS One 5(8):e12369.
2010
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13 | ARHGAP32, BCAR1, PPFIA4, PTPRS, TRIO
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| Receptor tyrosine phosphatase sigma (RPTPσ) regulates, p250GAP, a novel substrate that attenuates Rac signaling.
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| Chagnon MJ, Wu CL, Nakazawa T, Yamamoto T, Noda M, Blanchetot C, Tremblay ML.
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| Cell Signal 22(11):1626-33. Epub 2010 Jun 12.
2010
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14 | BCAR1
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| p130Cas is an essential transducer element in ErbB2 transformation.
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| Cabodi S, Tinnirello A, Bisaro B, Tornillo G, del Pilar Camacho-Leal M, Forni G, Cojoca R, Iezzi M, Amici A, Montani M, Eva A, Di Stefano P, Muthuswamy SK, Tarone G, Turco E, Defilippi P.
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| FASEB J 24(10):3796-808. Epub 2010 May 26.
2010
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15 | BCAR1
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| p130 Crk-associated substrate (CAS) in vascular smooth muscle.
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| Tang DD.
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| J Cardiovasc Pharmacol Ther 14(2):89-98. Epub 2009 Mar 27. Review.
2009
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16 | BCAR1
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| Relation among p130Cas, E-cadherin and beta-catenin expression, clinicopathologic significance and prognosis in human hepatocellular carcinoma.
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| Guo C, Liu QG, Yang W, Zhang ZL, Yao YM.
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| Hepatobiliary Pancreat Dis Int 7(5):490-6.
2008
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17 | BCAR1
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| p130CAS is required for netrin signaling and commissural axon guidance.
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| Liu G, Li W, Gao X, Li X, Jrgensen C, Park HT, Shin NY, Yu J, He ML, Hanks SK, Wu JY, Guan KL, Rao Y.
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| J Neurosci 27(4):957-68. 2007
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18 | NPHP1, NPHP4, TTC8, BCAR1, PTK2B
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| Characterization of the nephrocystin/nephrocystin-4 complex and subcellular localization of nephrocystin-4 to primary cilia and centrosomes.
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| Mollet G, Silbermann F, Delous M, Salomon R, Antignac C, Saunier S.
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| Hum Mol Genet 14(5):645-56. Epub 2005 Jan 20. 2005
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19 | INPPL1, BCAR1
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| SH2-containing 5'-inositol phosphatase, SHIP2, regulates cytoskeleton organization and ligand-dependent down-regulation of the epidermal growth factor receptor.
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| Prasad NK, Decker SJ.
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| J Biol Chem 280(13):13129-36. Epub 2005 Jan 24. 2005
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20 | BCAR1
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| Tyrosine phosphorylation of paxillin, FAK, and p130CAS: effects on cell spreading and migration.
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| Panetti TS.
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| Front Biosci 7:d143-50. Review. 2002
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21 | BCAR1, NPHP4, PTK2B
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| A gene mutated in nephronophthisis and retinitis pigmentosa encodes a novel protein, nephroretinin, conserved in evolution.
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| Otto E, Hoefele J, Ruf R, Mueller AM, Hiller KS, Wolf MT, Schuermann MJ, Becker A, Birkenhager R, Sudbrak R, Hennies HC, Nurnberg P, Hildebrandt F.
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| Am J Hum Genet 71(5):1161-7. 2002
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22 | BCAR1
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| Analysis of gene expression profile in p130(Cas)-deficient fibroblasts.
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| Nakamoto T, Suzuki T, Huang J, Matsumura T, Seo S, Honda H, Sakai R, Hirai H.
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| Biochem Biophys Res Commun 294(3):635-41. 2002
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23 | BCAR1
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| Tyrosine dephosphorylation, but not phosphorylation, of p130Cas is dependent on integrin alpha IIb beta 3-mediated aggregation in platelets: implication of p130Cas involvement in pathways unrelated to cytoskeletal reorganization.
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| Ohmori T, Yatomi Y, Inoue K, Satoh K, Ozaki Y.
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| Biochemistry 39(19):5797-807. 2000
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24 | BCAR1
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| Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment.
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| van der Flier S, Brinkman A, Look MP, Kok EM, Meijer-van Gelder ME, Klijn JG, Dorssers LC, Foekens JA.
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| J Natl Cancer Inst 92(2):120-7. 2000
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25 | BCAR1
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| BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells.
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| Brinkman A, van der Flier S, Kok EM, Dorssers LC.
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| J Natl Cancer Inst 92(2):112-20. 2000
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26 | BCAR1
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| Induction of antiestrogen resistance in human breast cancer cells by random insertional mutagenesis using defective retroviruses: identification of bcar-1, a common integration site.
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| Dorssers LC, van Agthoven T, Dekker A, van Agthoven TL, Kok EM.
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| Mol Endocrinol 7(7):870-8. 1993
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