| 1 | BAX, VDAC2
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| VDAC2 enables BAX to mediate apoptosis and limit tumor development.
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| Chin HS, Li MX, Tan IKL, Ninnis RL, Reljic B, Scicluna K, Dagley LF, Sandow JJ, Kelly GL, Samson AL, Chappaz S, Khaw SL, Chang C, Morokoff A, Brinkmann K, Webb A, Hockings C, Hall CM, Kueh AJ, Ryan MT, Kluck RM, Bouillet P, Herold MJ, Gray DHD, Huang DCS, van Delft MF, Dewson G.
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| Nat Commun 9(1):4976. doi: 10.1038/s41467-018-07309-4.
2018
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| 2 | BAX, VDAC2
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| The porin VDAC2 is the mitochondrial platform for Bax retrotranslocation.
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| Lauterwasser J, Todt F, Zerbes RM, Nguyen TN, Craigen W, Lazarou M, van der Laan M, Edlich F.
|
| Sci Rep 6:32994. doi: 10.1038/srep32994.
2016
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| 3 | BAK1, BAX
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| Differential retrotranslocation of mitochondrial Bax and Bak.
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| Todt F, Cakir Z, Reichenbach F, Emschermann F, Lauterwasser J, Kaiser A, Ichim G, Tait SW, Frank S, Langer HF, Edlich F.
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| EMBO J 34(1):67-80. doi: 10.15252/embj.201488806. Epub 2014 Nov 5.
2015
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| 4 | BAX, DRAM1
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| DRAM1 regulates apoptosis through increasing protein levels and lysosomal localization of BAX.
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| Guan JJ, Zhang XD, Sun W, Qi L, Wu JC, Qin ZH.
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| Cell Death Dis 6:e1624. doi: 10.1038/cddis.2014.546.
2015
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| 5 | BAX, BCL2L1
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| Bcl-xL stimulates Bax relocation to mitochondria and primes cells to ABT-737.
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| Renault TT, Teijido O, Missire F, Ganesan YT, Velours G, Arokium H, Beaumatin F, Llanos R, Athané A, Camougrand N, Priault M, Antonsson B, Dejean LM, Manon S.
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| Int J Biochem Cell Biol 64:136-46. doi: 10.1016/j.biocel.2015.03.020. Epub 2015 Apr 8.
2015
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| 6 | BAX, MOAP1, RASSF1
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| Modulator of apoptosis 1 (MOAP-1) is a tumor suppressor protein linked to the RASSF1A protein.
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| Law J, Salla M, Zare A, Wong Y, Luong L, Volodko N, Svystun O, Flood K, Lim J, Sung M, Dyck JR, Tan CT, Su YC, Yu VC, Mackey J, Baksh S.
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| J Biol Chem 290(40):24100-18. doi: 10.1074/jbc.M115.648345. Epub 2015 Aug 12.
2015
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| 7 | BAK1, BAX, OMA1
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| Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
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| Jiang X, Jiang H, Shen Z, Wang X.
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| Proc Natl Acad Sci U S A 111(41):14782-7. doi: 10.1073/pnas.1417253111. Epub 2014 Oct 1.
2014
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| 8 | BAK1, BAX
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| Bak core and latch domains separate during activation, and freed core domains form symmetric homodimers.
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| Brouwer JM, Westphal D, Dewson G, Robin AY, Uren RT, Bartolo R, Thompson GV, Colman PM, Kluck RM, Czabotar PE.
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| Mol Cell 55(6):938-46. doi: 10.1016/j.molcel.2014.07.016. Epub 2014 Aug 28.
2014
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| 9 | BAK1, BAX
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| Prosurvival Bcl-2 family members affect autophagy only indirectly, by inhibiting Bax and Bak.
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| Lindqvist LM, Heinlein M, Huang DC, Vaux DL.
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| Proc Natl Acad Sci U S A 111(23):8512-7. doi: 10.1073/pnas.1406425111. Epub 2014 May 27.
2014
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| 10 | BAK1, BAX
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| Organization of the mitochondrial apoptotic BAK pore: oligomerization of the BAK homodimers.
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| Aluvila S, Mandal T, Hustedt E, Fajer P, Choe JY, Oh KJ.
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| J Biol Chem 289(5):2537-51. doi: 10.1074/jbc.M113.526806. Epub 2013 Dec 11.
2014
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| 11 | BAX, VDAC2
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| Bax targets mitochondria by distinct mechanisms before or during apoptotic cell death: a requirement for VDAC2 or Bak for efficient Bax apoptotic function.
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| Ma SB, Nguyen TN, Tan I, Ninnis R, Iyer S, Stroud DA, Menard M, Kluck RM, Ryan MT, Dewson G.
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| Cell Death Differ 21(12):1925-35. doi: 10.1038/cdd.2014.119. Epub 2014 Aug 22.
2014
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| 12 | ATXN3, BAX, BCL2L1, MJD
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| Ataxin-3 protects cells against H2O2-induced oxidative stress by enhancing the interaction between Bcl-XL and Bax.
|
| Zhou L, Wang H, Wang P, Ren H, Chen D, Ying Z, Wang G.
|
| Neuroscience 243:14-21. doi: 10.1016/j.neuroscience.2013.03.047. Epub 2013 Apr 2.
2013
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| 13 | BAX, BCL2L2, CASP6
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| Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration.
|
| Cosker KE, Pazyra-Murphy MF, Fenstermacher SJ, Segal RA.
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| J Neurosci 33(12):5195-207. doi: 10.1523/JNEUROSCI.3862-12.2013.
2013
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| 14 | BAK1, BAX
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| Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune disease.
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| Mason KD, Lin A, Robb L, Josefsson EC, Henley KJ, Gray DH, Kile BT, Roberts AW, Strasser A, Huang DC, Waring P, O'Reilly LA.
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| Proc Natl Acad Sci U S A 110(7):2599-604. doi: 10.1073/pnas.1215097110. Epub 2013 Jan 24.
2013
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| 15 | BAK1, BAX
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| Proapoptotic Bax and Bak proteins form stable protein-permeable pores of tunable size.
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| Bleicken S, Landeta O, Landajuela A, Basañez G, García-Sáez AJ.
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| J Biol Chem 288(46):33241-52. doi: 10.1074/jbc.M113.512087. Epub 2013 Oct 7.
2013
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| 16 | BAK1, BAX
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| Direct activation of full-length proapoptotic BAK.
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| Leshchiner ES, Braun CR, Bird GH, Walensky LD.
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| Proc Natl Acad Sci U S A 110(11):E986-95. doi: 10.1073/pnas.1214313110. Epub 2013 Feb 12.
2013
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| 17 | BAX, CTBP1
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| AMP-activated protein kinase phosphorylates CtBP1 and down-regulates its activity.
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| Kim JH, Choi SY, Kang BH, Lee SM, Park HS, Kang GY, Bang JY, Cho EJ, Youn HD.
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| Biochem Biophys Res Commun 431(1):8-13. doi: 10.1016/j.bbrc.2012.12.117. Epub 2013 Jan 3.
2013
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| 18 | BAX, ING1, PCNA
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| ING1 induces apoptosis through direct effects at the mitochondria.
|
| Bose P, Thakur S, Thalappilly S, Ahn BY, Satpathy S, Feng X, Suzuki K, Kim SW, Riabowol K.
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| Cell Death Dis 4:e788. doi: 10.1038/cddis.2013.321. Erratum in: Cell Death Dis. 2013;4:e837.
2013
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| 19 | BAK1, BAX, BBC3, BCL2L11
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| PUMA and BIM are required for oncogene inactivation-induced apoptosis.
|
| Bean GR, Ganesan YT, Dong Y, Takeda S, Liu H, Chan PM, Huang Y, Chodosh LA, Zambetti GP, Hsieh JJ, Cheng EH.
|
| Sci Signal 6(268):ra20. doi: 10.1126/scisignal.2003483.
2013
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| 20 | BAX, MUC1
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| The MUC1-C oncoprotein binds to the BH3 domain of the pro-apoptotic BAX protein and blocks BAX function.
|
| Ahmad R, Alam M, Rajabi H, Kufe D.
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| J Biol Chem 287(25):20866-75. doi: 10.1074/jbc.M112.357293. Epub 2012 Apr 27.
2012
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| 21 | BAX, PRKN
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| The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax.
|
| Johnson BN, Berger AK, Cortese GP, Lavoie MJ.
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| Proc Natl Acad Sci U S A 109(16):6283-8. doi: 10.1073/pnas.1113248109. Epub 2012 Mar 29. 2012
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| 22 | BAK1, BAX
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| Bax regulates primary necrosis through mitochondrial dynamics.
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| Whelan RS, Konstantinidis K, Wei AC, Chen Y, Reyna DE, Jha S, Yang Y, Calvert JW, Lindsten T, Thompson CB, Crow MT, Gavathiotis E, Dorn GW 2nd, O'Rourke B, Kitsis RN.
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| Proc Natl Acad Sci U S A 109(17):6566-71. doi: 10.1073/pnas.1201608109. Epub 2012 Apr 9.
2012
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| 23 | BAX, BCL2L2
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| Bcl-w promotes cell invasion by blocking the invasion-suppressing action of Bax.
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| Kim EM, Kim J, Park JK, Hwang SG, Kim WJ, Lee WJ, Kang SW, Um HD.
|
| Cell Signal 24(6):1163-72.
2012
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| 24 | BAX, TOMM22
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| The cytosolic domain of human Tom22 modulates human Bax mitochondrial translocation and conformation in yeast.
|
| Renault TT, Grandier-Vazeille X, Arokium H, Velours G, Camougrand N, Priault M, Teijido O, Dejean LM, Manon S.
|
| FEBS Lett 586(2):116-21. doi: 10.1016/j.febslet.2011.12.003. Epub 2011 Dec 17.
2012
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| 25 | BAX, BCL2L1, MCL1
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| Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis.
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| Czabotar PE, Lee EF, Thompson GV, Wardak AZ, Fairlie WD, Colman PM.
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| J Biol Chem 286(9):7123-31. Epub 2011 Jan 3.
2011
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| 26 | BAK1, BAX
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| Bcl-2 proteins regulate ER membrane permeability to luminal proteins during ER stress-induced apoptosis.
|
| Wang X, Olberding KE, White C, Li C.
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| Cell Death Differ. 18(1):38-47. 2011
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| 27 | BAK1, BAX
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| Bcl-2 family interaction with the mitochondrial morphogenesis machinery.
|
| Cleland MM, Norris KL, Karbowski M, Wang C, Suen DF, Jiao S, George NM, Luo X, Li Z, Youle RJ.
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| Cell Death Differ. 18(2):235-47 2011
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| 28 | BAX, HIF1AN
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| Prevention of apoptosis by the interaction between FIH1 and Bax.
|
| Yan B, Kong M, Chen YH.
|
| Mol Cell Biochem 348(1-2):1-9. Epub 2010 Nov 11.
2011
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| 29 | BAX, RNF144B
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| IBRDC2, an IBR-type E3 ubiquitin ligase, is a regulatory factor for Bax and apoptosis activation.
|
| Benard G, Neutzner A, Peng G, Wang C, Livak F, Youle RJ, Karbowski M.
|
| EMBO J 29(8):1458-71. Epub 2010 Mar 18.PMID: 20300062 2010
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| 30 | BAK1, BAX, VDAC2
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| Inhibition of Bak activation by VDAC2 is dependent on the Bak transmembrane anchor.
|
| Lazarou M, Stojanovski D, Frazier AE, Kotevski A, Dewson G, Craigen WJ, Kluck RM, Vaux DL, Ryan MT.
|
| J Biol Chem 285(47):36876-83. Epub 2010 Sep 17.
2010
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| 31 | BAK1, BAX, BBC3, BCL2L11, BID
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| BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.
|
| Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.
|
| Science 330(6009):1390-3.
2010
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| 32 | BAK1, BAX
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| A role for proapoptotic Bax and Bak in T-cell differentiation and transformation.
|
| Biswas S, Shi Q, Matise L, Cleveland S, Dave U, Zinkel S.
|
| Blood 116(24):5237-46. Epub 2010 Sep 2.
2010
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| 33 | BAX, BCL2L11, RACK1
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| A novel pro-apoptotic function of RACK1: suppression of Src activity in the intrinsic and Akt pathways.
|
| Mamidipudi V, Cartwright CA.
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| Oncogene 28(50):4421-33. Epub 2009 Sep 21.PMID: 19767770 2009
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| 34 | BAX, IFNGR2
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| The C-terminus of interferon gamma receptor beta chain (IFNgammaR2) has antiapoptotic activity as a Bax inhibitor.
|
| Gomez JA, Sun W, Gama V, Hajkova D, Yoshida T, Wu Z, Miyagi M, Pink JJ, Jackson MW, Danielpour D, Matsuyama S.
|
| Cancer Biol Ther 8(18):1771-86. Epub 2009 Sep 20.PMID: 19657228 2009
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| 35 | BAX, DND1
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| BAX-mediated cell death affects early germ cell loss and incidence of testicular teratomas in Dnd1(Ter/Ter) mice.
|
| Cook MS, Coveney D, Batchvarov I, Nadeau JH, Capel B.
|
| Dev Biol 328(2):377-83. Epub 2009 Feb 6.
2009
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| 36 | BAX, KCNA3
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| Mitochondrial potassium channel Kv1.3 mediates Bax-induced apoptosis in lymphocytes.
|
| Szabó I, Bock J, Grassmé H, Soddemann M, Wilker B, Lang F, Zoratti M, Gulbins E.
|
| Proc Natl Acad Sci U S A 105(39):14861-6. Epub 2008 Sep 25.
2008
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| 37 | BAX
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| Cholesterol effects on BAX pore activation.
|
| Christenson E, Merlin S, Saito M, Schlesinger P.
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| J Mol Biol 381(5):1168-83. Epub 2008 Jun 20.
2008
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| 38 | BAX
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| BAX activation is initiated at a novel interaction site.
|
| Gavathiotis E, Suzuki M, Davis ML, Pitter K, Bird GH, Katz SG, Tu HC, Kim H, Cheng EH, Tjandra N, Walensky LD.
|
| Nature 455(7216):1076-81.
2008
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| 39 | BAX, NPM1
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| Characterisation of the Bax-nucleophosmin interaction: the importance of the Bax C-terminus.
|
| Thompson J, Finlayson K, Salvo-Chirnside E, MacDonald D, McCulloch J, Kerr L, Sharkey J.
|
| Apoptosis 13(3):394-403.PMID: 18214681 2008
|
| 40 | BAX,TOMM22
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| TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax.
|
| Bellot G, Cartron PF, Er E, Oliver L, Juin P, Armstrong LC, Bornstein P, Mihara K, Manon S, Vallette FM.
|
| Cell Death Differ 14(4):785-94. Epub 2006 Nov 10. 2007
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| 41 | BAX
|
| Bax gene G(-248)A promoter polymorphism is associated with increased lifespan of the neutrophils of patients with osteomyelitis.
|
| Ocana MG, Valle-Garay E, Montes AH, Meana A, Carton JA, Fierer J, Celada A, Asensi V.
|
| Genet Med 9(4):249-55. 2007
|
| 42 | AIFM1, ENDOG, BAX
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| The pro-inflammatory oxidant hypochlorous acid induces Bax-dependent mitochondrial permeabilisation and cell death through AIF-/EndoG-dependent pathways.
|
| Whiteman M, Chu SH, Siau JL, Rose P, Sabapathy K, Schantz JT, Cheung NS, Spencer JP, Armstrong JS.
|
| Cell Signal 19(4):705-14. Epub 2006 Nov 14. 2007
|
| 43 | BID, BAX
|
| The mitochondrial TOM complex is required for tBid/Bax-induced cytochrome c release.
|
| Ott M, Norberg E, Walter KM, Schreiner P, Kemper C, Rapaport D, Zhivotovsky B, Orrenius S.
|
| J Biol Chem 282(38):27633-9. Epub 2007 Jul 16. 2007
|
| 44 | BAK1, BAX, BNIP3
|
| Bnip3 mediates mitochondrial dysfunction and cell death through Bax and Bak.
|
| Kubli DA, Ycaza JE, Gustafsson AB.
|
| Biochem J 405(3):407-15.
2007
|
| 45 | BAX, PRKCZ
|
| Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.
|
| Xin M, Gao F, May WS, Flagg T, Deng X.
|
| J Biol Chem 282(29):21268-77. Epub 2007 May 24.PMID: 1752516 2007
|
| 46 | BAX, MOAP1
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| Inhibition of ubiquitin-mediated degradation of MOAP-1 by apoptotic stimuli promotes Bax function in mitochondria.
|
| Fu NY, Sukumaran SK, Yu VC.
|
| Proc Natl Acad Sci U S A 104(24):10051-6. Epub 2007 May 29.
2007
|
| 47 | BAX, BAK1, ERN1
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| Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.
|
| Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ.
|
| Science 312(5773):572-6. 2006
|
| 48 | BAX, KRAS, MOAP1, RASSF1
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| The RASSF1A tumor suppressor activates Bax via MOAP-1.
|
| Vos MD, Dallol A, Eckfeld K, Allen NP, Donninger H, Hesson LB, Calvisi D, Latif F, Clark GJ.
|
| J Biol Chem 281(8):4557-63. Epub 2005 Dec 12.
2006
|
| 49 | BAX, MOAP1
|
| MAP-1 is a mitochondrial effector of Bax.
|
| Tan KO, Fu NY, Sukumaran SK, Chan SL, Kang JH, Poon KL, Chen BS, Yu VC.
|
| Proc Natl Acad Sci U S A 102(41):14623-8. Epub 2005 Sep 30.
2005
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| 50 | BAK1, BAX
|
| Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease.
|
| Takeuchi O, Fisher J, Suh H, Harada H, Malynn BA, Korsmeyer SJ.
|
| Proc Natl Acad Sci U S A. 102(32):11272-7. 2005
|
| 51 | BAX, BBC3
|
| The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA.
|
| Cartron PF, Gallenne T, Bougras G, Gautier F, Manero F, Vusio P, Meflah K, Vallette FM, Juin P.
|
| Mol Cell. 16(5):807-18. 2004
|
| 52 | BAX, CRYAB
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| Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis.
|
| Mao YW, Liu JP, Xiang H, Li DW.
|
| Cell Death Differ. 11(5):512-26. 2004
|
| 53 | BAK1, BAX
|
| BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis.
|
| Scorrano L, Oakes SA, Opferman JT, Cheng EH, Sorcinelli MD, Pozzan T, Korsmeyer SJ.
|
| Science 300(5616):135-9. Epub 2003 Mar 06. 2003
|
| 54 | BCL2L10, BAX, BAK1
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| Characterization of the anti-apoptotic mechanism of Bcl-B.
|
| Zhai D, Ke N, Zhang H, Ladror U, Joseph M, Eichinger A, Godzik A, Ng SC, Reed JC.
|
| Biochem J 376(Pt 1):229-36. 2003
|
| 55 | BAX, MTRNR2L1
|
| Humanin peptide suppresses apoptosis by interfering with Bax activation.
|
| Guo B, Zhai D, Cabezas E, Welsh K, Nouraini S, Satterthwait AC, Reed JC.
|
| Nature 423(6938):456-61. Epub 2003 May 4. 2003
|
| 56 | BAX, VDAC1
|
| Identification of the protein-protein contact site and interaction mode of human VDAC1 with Bcl-2 family proteins.
|
| Shi Y, Chen J, Weng C, Chen R, Zheng Y, Chen Q, Tang H.
|
| Biochem Biophys Res Commun. 305(4):989-96. 2003
|
| 57 | BAX
|
| 14-3-3 Interacts directly with and negatively regulates pro-apoptotic Bax.
|
| Nomura M, Shimizu S, Sugiyama T, Narita M, Ito T, Matsuda H, Tsujimoto Y.
|
| J Biol Chem. 278(3):2058-65. 2003
|
| 58 | BAX
|
| The expression of a new variant of the pro-apoptotic molecule Bax, Baxpsi, is correlated with an increased survival of glioblastoma multiforme patients.
|
| Cartron PF, Oliver L, Martin S, Moreau C, LeCabellec MT, Jezequel P, Meflah K, Vallette FM.
|
| Hum Mol Genet 11(6):675-87. 2002
|
| 59 | BAX
|
| Cytosolic heat shock protein 60, apoptosis, and myocardial injury.
|
| Kirchhoff SR, Gupta S, Knowlton AA.
|
| Circulation. 105(24):2899-904. 2002
|
| 60 | BAX, SH3GLB1, SH3GLB2
|
| SH3GLB, a New Endophilin-Related Protein Family Featuring an SH3 Domain.
|
| Pierrat B, Simonen M, Cueto M, Mestan J, Ferrigno P, Heim J.
|
| Genomics 71(2):222-34. 2001
|
| 61 | BAX, SH3GLB1
|
| Molecular cloning and characterization of Bif-1. A novel Src homology 3 domain-containing protein that associates with Bax.
|
| Cuddeback SM, Yamaguchi H, Komatsu K, Miyashita T, Yamada M, Wu C, Singh S, Wang HG.
|
| J Biol Chem 276(23):20559-65. 2001
|
| 62 | BAX, MOAP1
|
| MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains.
|
| Tan KO, Tan KM, Chan SL, Yee KS, Bevort M, Ang KC, Yu VC.
|
| J Biol Chem 276(4):2802-7. Epub 2000 Nov 01. 2001
|
| 63 | BAK1, BAX
|
| Tumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19K.
|
| Sundararajan R, Cuconati A, Nelson D, White E.
|
| J Biol Chem. 276(48):45120-7. 2001
|
| 64 | BAX
|
| The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax.
|
| Samuel T, Weber HO, Rauch P, Verdoodt B, Eppel JT, McShea A, Hermeking H, Funk JO.
|
| J Biol Chem. 276(48):45201-6. 2001
|
| 65 | BAX
|
| Mutation of BAX occurs infrequently in acquired immunodeficiency syndrome-related non-Hodgkin's lymphomas.
|
| Gaidano G, Vivenza D, Forconi F, Capello D, Gloghini A, Bhatia K, Gutierrez M, Gallicchio M, Avanzi GC, Fassone L, Ariatti C, Buonaiuto D, Cingolani A, Saglio G, Tirelli U, Larocca LM, Dalla-Favera R, Carbone A.
|
| Genes Chromosomes Cancer 27(2):177-82 2000
|
| 66 | BAX
|
| Bax degradation by the ubiquitin/proteasome-dependent pathway: involvement in tumor survival and progression.
|
| Li B, Dou QP.
|
| Proc Natl Acad Sci U S A 97(8):3850-5. 2000
|
| 67 | ATM, BAX
|
| Atm and Bax cooperate in ionizing radiation-induced apoptosis in the central nervous system.
|
| Chong MJ, Murray MR, Gosink EC, Russell HR, Srinivasan A, Kapsetaki M, Korsmeyer SJ, McKinnon PJ.
|
| Proc Natl Acad Sci U S A 97(2):889-94. 2000
|
| 68 | BAX
|
| Structure of bax. Coregulation Of dimer formation and intracellular localization.
|
| Suzuki M, Youle RJ, Tjandra N.
|
| Cell 103(4):645-54. 2000
|
| 69 | BAX
|
| Impaired BAX protein expression in breast cancer: mutational analysis of the BAX and the p53 gene.
|
| Sturm I, Papadopoulos S, Hillebrand T, Benter T, Luck HJ, Wolff G, Dorken B, Daniel PT.
|
| Int J Cancer 87(4):517-21. 2000
|
| 70 | BAX
|
| Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cells
|
| Zhang H, Cowan-Jacob SW, Simonen M, Greenhalf W, Heim J, Meyhack B.
|
| J Biol Chem. 275(15):11092-9. 2000
|
| 71 | BAK1, BAX, MCL1
|
| MCL-1S, a splicing variant of the antiapoptotic BCL-2 family member MCL-1, encodes a proapoptotic protein possessing only the BH3 domain.
|
| Bae J, Leo CP, Hsu SY, Hsueh AJ.
|
| J Biol Chem. 275(33):25255-61. 2000
|
| 72 | BAK1, BAX
|
| The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
|
| Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, Chen Y, Wei M, Eng VM, Adelman DM, Simon MC, Ma A, Golden JA, Evan G, Korsmeyer SJ, MacGregor GR, Thompson CB.
|
| Mol Cell 6(6):1389-99. 2000
|
| 73 | BAX
|
| Identification and characterization of baxepsilon, a novel bax variant missing the BH2 and the transmembrane domains.
|
| Shi B, et al.
|
| Biochem Biophys Res Commun 254(3):779-85. 1999
|
| 74 | BAK1, BAX, BCL2
|
| Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC.
|
| Shimizu S, et al.
|
| Nature 399(6735):483-7. 1999
|
| 75 | BIRC5, BAX, BCL2
|
| Analysis of Bcl-2, Bax and Survivin genes in uterine cancer.
|
| Saitoh Y, et al.
|
| Int J Oncol 15(1):137-41 1999
|
| 76 | BAK1, BAX
|
| Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members.
|
| Holmgreen SP, Huang DC, Adams JM, Cory S.
|
| Cell Death Differ. 6(6):525-32. 1999
|
| 77 | BAX
|
| Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis.
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