Citations for
1BAP1, UCHL3, UCHL5
Ubiquitin carboxyl-terminal hydrolases: involvement in cancer progression and clinical implications.
Fang Y, Shen X.
Cancer Metastasis Rev 36(4):669-682. doi: 10.1007/s10555-017-9702-0. Review. 2017
2ASXL1, ASXL2, ASXL3, BAP1
BAP1/ASXL1 recruitment and activation for H2A deubiquitination.
Sahtoe DD, van Dijk WJ, Ekkebus R, Ovaa H, Sixma TK.
Nat Commun 7:10292. doi: 10.1038/ncomms10292. 2016
3BAP1
BAP1 regulates cell cycle progression through E2F1 target genes and mediates transcriptional silencing via H2A monoubiquitination in uveal melanoma cells.
Pan H, Jia R, Zhang L, Xu S, Wu Q, Song X, Zhang H, Ge S, Leon Xu X, Fan X.
Int J Biochem Cell Biol 60:176-84. doi: 10.1016/j.biocel.2015.01.001. Epub 2015 Jan 9. 2015
4BAP1
Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma Patients.
Cebulla CM, Binkley EM, Pilarski R, Massengill JB, Rai K, Liebner DA, Marino MJ, Singh AD, Abdel-Rahman MH.
Ophthalmic Genet phthalmic Genet. 2015 Feb 17:1-6. [Epub ahead of print] 2015
5ASXL1, ASXL2, BAP1
The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
Daou S, Hammond-Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono NV, Nkwe NS, Motorina A, Pak H, Yu H, Wurtele H, Milot E, Mallette FA, Carbone M, Affar el B.
J Biol Chem 290(48):28643-63. doi: 10.1074/jbc.M115.661553. 2015
6BAP1
Germline mutations in BAP1 impair its function in DNA double-strand break repair.
Ismail IH, Davidson R, Gagné JP, Xu ZZ, Poirier GG, Hendzel MJ.
Cancer Res 74(16):4282-94. doi: 10.1158/0008-5472.CAN-13-3109. Epub 2014 Jun 3. 2014
7BAP1
Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair.
Yu H, Pak H, Hammond-Martel I, Ghram M, Rodrigue A, Daou S, Barbour H, Corbeil L, Hébert J, Drobetsky E, Masson JY, Di Noia JM, Affar el B.
Proc Natl Acad Sci U S A 111(1):285-90. doi: 10.1073/pnas.1309085110. Epub 2013 Dec 17. 2014
8BAP1, EIF1AX, GNA11, GNAQ
Chromosome 3 status combined with BAP1 and EIF1AX mutation profiles are associated with metastasis in uveal melanoma.
Ewens KG, Kanetsky PA, Richards-Yutz J, Purrazzella J, Shields CL, Ganguly T, Ganguly A.
Invest Ophthalmol Vis Sci 55(8):5160-7. doi: 10.1167/iovs.14-14550. 2014
9BAP1
BAP1 is phosphorylated at serine 592 in S-phase following DNA damage.
Eletr ZM, Yin L, Wilkinson KD.
FEBS Lett 587(24):3906-11. doi: 10.1016/j.febslet.2013.10.035. Epub 2013 Nov 5. 2013
10BAP1, HCFC1
BAP1 loss defines a new class of renal cell carcinoma.
Peña-Llopis S, Vega-Rubín-de-Celis S, Liao A, Leng N, Pavía-Jiménez A, Wang S, Yamasaki T, Zhrebker L, Sivanand S, Spence P, Kinch L, Hambuch T, Jain S, Lotan Y, Margulis V, Sagalowsky AI, Summerour PB, Kabbani W, Wong SW, Grishin N, Laurent M, Xie XJ, Haudenschild CD, Ross MT, Bentley DR, Kapur P, Brugarolas J.
Nat Genet 44(7):751-9. doi: 10.1038/ng.2323. Erratum in: Nat Genet. 2012 Sep;44(9):1072. 2012
11BAP1, HCFC1, OGT
Loss of the tumor suppressor BAP1 causes myeloid transformation.
Dey A, Seshasayee D, Noubade R, French DM, Liu J, Chaurushiya MS, Kirkpatrick DS, Pham VC, Lill JR, Bakalarski CE, Wu J, Phu L, Katavolos P, LaFave LM, Abdel-Wahab O, Modrusan Z, Seshagiri S, Dong K, Lin Z, Balazs M, Suriben R, Newton K, Hymowitz S, Garcia-Manero G, Martin F, Levine RL, Dixit VM.
Science 337(6101):1541-6. 2012
12ASXL1, BAP1, HCFC1
The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, Olshen A, Rusch V, Ladanyi M.
Nat Genet 43(7):668-72. doi: 10.1038/ng.855. 2011
13BAP1
Germline BAP1 mutations and tumor susceptibility.
Goldstein AM.
Nat Genet 43(10):925-6. doi: 10.1038/ng.956. No abstract available. 2011
14BAP1
Germline mutations in BAP1 predispose to melanocytic tumors.
Wiesner T, Obenauf AC, Murali R, Fried I, Griewank KG, Ulz P, Windpassinger C, Wackernagel W, Loy S, Wolf I, Viale A, Lash AE, Pirun M, Socci ND, Rütten A, Palmedo G, Abramson D, Offit K, Ott A, Becker JC, Cerroni L, Kutzner H, Bastian BC, Speicher MR.
Nat Genet 43(10):1018-21. doi: 10.1038/ng.910. 2011
15BAP1
Germline BAP1 mutations predispose to malignant mesothelioma.
Testa JR, Cheung M, Pei J, Below JE, Tan Y, Sementino E, Cox NJ, Dogan AU, Pass HI, Trusa S, Hesdorffer M, Nasu M, Powers A, Rivera Z, Comertpay S, Tanji M, Gaudino G, Yang H, Carbone M.
Nat Genet 43(10):1022-5. doi: 10.1038/ng.912. 2011
16BAP1, COX7C, HCFC1, YY1
The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.
Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky E, Milot E, Shi Y, Affar el B.
Mol Cell Biol 30(21):5071-85. Epub 2010 Aug 30. 2010
17BAP1
Frequent mutation of BAP1 in metastasizing uveal melanomas.
Harbour JW, Onken MD, Roberson ED, Duan S, Cao L, Worley LA, Council ML, Matatall KA, Helms C, Bowcock AM.
Science 330(6009):1410-3. Epub 2010 Nov 4. 2010
18BAP1, HCFC1
The deubiquitinating enzyme BAP1 regulates cell growth via interaction with HCF-1.
Machida YJ, Machida Y, Vashisht AA, Wohlschlegel JA, Dutta A.
J Biol Chem 284(49):34179-88. Epub 2009 Oct 8.PMID: 19815555 2009
19BAP1, HCFC1
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.
Misaghi S, Ottosen S, Izrael-Tomasevic A, Arnott D, Lamkanfi M, Lee J, Liu J, O'Rourke K, Dixit VM, Wilson AC.
Mol Cell Biol 29(8):2181-92. Epub 2009 Feb 2.PMID: 19188440 2009
20BAP1
BRCA1-associated protein-1 is a tumor suppressor that requires deubiquitinating activity and nuclear localization.
Ventii KH, Devi NS, Friedrich KL, Chernova TA, Tighiouart M, Van Meir EG, Wilkinson KD.
Cancer Res 68(17):6953-62. 2008
21BAP1
BAP1 : a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression.
Jensen DE, et al.
Oncogene 16 : 1097-1112. 1998