1 | BAG6, RAB8A
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| Cytoplasmic control of Rab family small GTPases through BAG6.
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| Takahashi T, Minami S, Tsuchiya Y, Tajima K, Sakai N, Suga K, Hisanaga SI, Ohbayashi N, Fukuda M, Kawahara H.
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| EMBO Rep 20(4). pii: e46794. doi: 10.15252/embr.201846794. Epub 2019 Feb 25.
2019
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2 | BAG6, UBL4A
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| Structure of a BAG6 (Bcl-2-associated athanogene 6)-Ubl4a (ubiquitin-like protein 4a) complex reveals a novel binding interface that functions in tail-anchored protein biogenesis.
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| Kuwabara N, Minami R, Yokota N, Matsumoto H, Senda T, Kawahara H, Kato R.
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| J Biol Chem 290(15):9387-98. doi: 10.1074/jbc.M114.631804. Epub 2015 Feb 20.
2015
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3 | BAG6, GET4, UBL4A
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| Bag6 complex contains a minimal tail-anchor-targeting module and a mock BAG domain.
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| Mock JY, Chartron JW, Zaslaver M, Xu Y, Ye Y, Clemons WM Jr.
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| Proc Natl Acad Sci U S A 112(1):106-11. doi: 10.1073/pnas.1402745112. Epub 2014 Dec 22.
2015
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4 | BAG6, TRPS1
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| Nuclear cathepsin D enhances TRPS1 transcriptional repressor function to regulate cell cycle progression and transformation in human breast cancer cells.
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| Bach AS, Derocq D, Laurent-Matha V, Montcourrier P, Sebti S, Orsetti B, Theillet C, Gongora C, Pattingre S, Ibing E, Roger P, Linares LK, Reinheckel T, Meurice G, Kaiser FJ, Gespach C, Liaudet-Coopman E.
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| Oncotarget 6(29):28084-103. doi: 10.18632/oncotarget.4394.
2015
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5 | AMFR, BAG6, UBL4A, USP13
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| USP13 antagonizes gp78 to maintain functionality of a chaperone in ER-associated degradation.
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| Liu Y, Soetandyo N, Lee JG, Liu L, Xu Y, Clemons WM Jr, Ye Y.
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| Elife 3:e01369. doi: 10.7554/eLife.01369. Epub 2014 Jan 14.
2014
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6 | BAG6, SGTA, UBL4A
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| Solution structure of the SGTA dimerisation domain and investigation of its interactions with the ubiquitin-like domains of BAG6 and UBL4A.
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| Darby JF, Krysztofinska EM, Simpson PJ, Simon AC, Leznicki P, Sriskandarajah N, Bishop DS, Hale LR, Alfano C, Conte MR, Martínez-Lumbreras S, Thapaliya A, High S, Isaacson RL.
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| PLoS One 9(11):e113281. doi: 10.1371/journal.pone.0113281. eCollection 2014.
2014
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7 | BAG6, GET4, UBL4A
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| Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death.
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| Krenciute G, Liu S, Yucer N, Shi Y, Ortiz P, Liu Q, Kim BJ, Odejimi AO, Leng M, Qin J, Wang Y.
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| J Biol Chem 288(28):20547-57. doi: 10.1074/jbc.M112.443416. Epub 2013 May 30.
2013
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8 | BAG6, GET4, UBL4A
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| A ubiquitin-like domain recruits an oligomeric chaperone to a retrotranslocation complex in endoplasmic reticulum-associated degradation.
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| Xu Y, Liu Y, Lee JG, Ye Y.
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| J Biol Chem 288(25):18068-76. doi: 10.1074/jbc.M112.449199. Epub 2013 May 12.
2013
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9 | BAG6, SGTA, UBL4A
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| The association of BAG6 with SGTA and tail-anchored proteins.
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| Leznicki P, Roebuck QP, Wunderley L, Clancy A, Krysztofinska EM, Isaacson RL, Warwicker J, Schwappach B, High S.
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| PLoS One 8(3):e59590. doi: 10.1371/journal.pone.0059590. Epub 2013 Mar 22.
2013
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10 | BAG6, HAVCR2
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| Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.
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| Rangachari M, Zhu C, Sakuishi K, Xiao S, Karman J, Chen A, Angin M, Wakeham A, Greenfield EA, Sobel RA, Okada H, McKinnon PJ, Mak TW, Addo MM, Anderson AC, Kuchroo VK.
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| Nat Med 18(9):1394-400.
2012
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11 | BAG6, SGTA
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| SGTA antagonizes BAG6-mediated protein triage.
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| Leznicki P, High S.
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| Proc Natl Acad Sci U S A 109(47):19214-9. doi: 10.1073/pnas.1209997109. Epub 2012 Nov 5.
2012
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12 | BAG6
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| BAG-6 is essential for selective elimination of defective proteasomal substrates.
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| Minami R, Hayakawa A, Kagawa H, Yanagi Y, Yokosawa H, Kawahara H.
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| J Cell Biol 190(4):637-50. Epub 2010 Aug 16.
2010
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13 | ASNA1, BAG6
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| Bat3 promotes the membrane integration of tail-anchored proteins.
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| Leznicki P, Clancy A, Schwappach B, High S.
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| J Cell Sci 123(Pt 13):2170-8. Epub 2010 Jun 1.
2010
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14 | ASNA1, BAG6, GET4, UBL4A
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| A ribosome-associating factor chaperones tail-anchored membrane proteins.
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| Mariappan M, Li X, Stefanovic S, Sharma A, Mateja A, Keenan RJ, Hegde RS.
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| Nature 466(7310):1120-4. doi: 10.1038/nature09296. Epub 2010 Aug 1.
2010
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15 | BAG6
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| Sequential interplay between BAG6 and HSP70 upon heat shock.
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| Corduan A, Lecomte S, Martin C, Michel D, Desmots F.
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| Cell Mol Life Sci 66(11-12):1998-2004.
2009
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16 | BAG6, ZNF395
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| Scythe/BAT3 regulates apoptotic cell death induced by papillomavirus binding factor in human osteosarcoma.
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| Tsukahara T, Kimura S, Ichimiya S, Torigoe T, Kawaguchi S, Wada T, Yamashita T, Sato N.
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| Cancer Sci 100(1):47-53. Epub 2008 Oct 29.
2009
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17 | BAG6, CLPTM1L, MSH5
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| Common 5p15.33 and 6p21.33 variants influence lung cancer risk.
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| Wang Y, Broderick P, Webb E, Wu X, Vijayakrishnan J, Matakidou A, Qureshi M, Dong Q, Gu X, Chen WV, Spitz MR, Eisen T, Amos CI, Houlston RS.
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| Nat Genet 40(12):1407-9. Epub 2008 Nov 2. 2008
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18 | AIFM1, BAG6
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| Scythe regulates apoptosis-inducing factor stability during endoplasmic reticulum stress-induced apoptosis.
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| Desmots F, Russell HR, Michel D, McKinnon PJ.
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| J Biol Chem 283(6):3264-71. Epub 2007 Dec 3.PMID: 18056262 2008
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19 | BAG6, HSPA2
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| Bat3 deficiency accelerates the degradation of Hsp70-2/HspA2 during spermatogenesis.
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| Sasaki T, Marcon E, McQuire T, Arai Y, Moens PB, Okada H.
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| J Cell Biol 182(3):449-58. Epub 2008 Aug 4. 2008
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20 | BAG6, SGTA
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| Human SGT interacts with Bag-6/Bat-3/Scythe and cells with reduced levels of either protein display persistence of few misaligned chromosomes and mitotic arrest.
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| Winnefeld M, Grewenig A, Schnölzer M, Spring H, Knoch TA, Gan EC, Rommelaere J, Cziepluch C.
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| Exp Cell Res 312(13):2500-14. Epub 2006 May 13.
2006
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21 | BAG6
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| Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3.
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| Wu YH, Shih SF, Lin JY.
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| J Biol Chem 279(18):19264-75. Epub 2004 Feb 11. 2004
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22 | BAG6
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| Human Scythe contains a functional nuclear localization sequence and remains in the nucleus during staurosporine-induced apoptosis.
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| Manchen ST, Hubberstey AV.
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| Biochem Biophys Res Commun 287(5):1075-82. 2001
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23 | BAG6, BAT2, BAT@
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| A gene pair from the human major histocompatibility complex encodes large proline-rich proteins with multiple repeated motifs and a single ubiquitin-like domain.
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| Banerji J, Sands J, Strominger JL, Spies T.
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| Proc Natl Acad Sci U S A 87(6):2374-8. 1990
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24 | ABHD16A, BAG6, BAT2, BAT4, BAT@, D6S51, D6S52, D6S53, D6S81E, DDX39B, LTA, LTB, TNF
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| A new cluster of genes within the human major histocompatibility complex.
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| Spies T, Blanck G, Bresnahan M, Sands J, Strominger JL.
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| Science 243(4888):214-7. 1989
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25 | ABHD16A, BAG6, BAT2, BAT4, BAT@, DDX39B, EHMT2, ZBTB12
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| Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B.
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| Spies T, Bresnahan M, Strominger JL.
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| Proc Natl Acad Sci U S A 86(22):8955-8. 1989
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