| 1 | BACH1, HOXB8
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| Oncogenic HOXB8 is driven by MYC-regulated super-enhancer and potentiates colorectal cancer invasiveness via BACH1.
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| Ying Y, Wang Y, Huang X, Sun Y, Zhang J, Li M, Zeng J, Wang M, Xiao W, Zhong L, Xu B, Li L, Tao Q, Wang X, Shu XS.
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| Oncogene 39(5):1004-1017. doi: 10.1038/s41388-019-1013-1. Epub 2019 Oct 7.
2020
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| 2 | BACH1, BACH2
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| The double knockout of Bach1 and Bach2 in mice reveals shared compensatory mechanisms in regulating alveolar macrophage function and lung surfactant homeostasis.
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| Ebina-Shibuya R, Watanabe-Matsui M, Matsumoto M, Itoh-Nakadai A, Funayama R, Nakayama K, Muto A, Igarashi K.
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| J Biochem Biochem. 2016 Jul 7. pii: mvw041. [Epub ahead of print]
2016
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| 3 | BACH1
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| BACH1, the master regulator gene: A novel candidate target for cancer therapy.
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| Davudian S, Mansoori B, Shajari N, Mohammadi A, Baradaran B.
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| Gene 588(1):30-7. doi: 10.1016/j.gene.2016.04.040. Epub 2016 Apr 22. Review.
2016
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| 4 | BACH1, BACH2, MAFG, MAFK, MAfF, NFE2, NFE2L2
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| Small Maf proteins (MafF, MafG, MafK): History, structure and function.
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| Katsuoka F, Yamamoto M.
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| Gene 586(2):197-205. doi: 10.1016/j.gene.2016.03.058. Epub 2016 Apr 5. Review.
2016
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| 5 | BACH1
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| Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation.
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| Wang X, Liu J, Jiang L, Wei X, Niu C, Wang R, Zhang J, Meng D, Yao K.
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| Oxid Med Cell Longev 2016:6234043. doi: 10.1155/2016/6234043. Epub 2016 Feb 29.
2016
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| 6 | BACH1
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| Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1.
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| Takada T, Miyaki S, Ishitobi H, Hirai Y, Nakasa T, Igarashi K, Lotz MK, Ochi M.
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| Arthritis Res Ther 17:285. doi: 10.1186/s13075-015-0792-1.
2015
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| 7 | BACH1, TCF4
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| Bach1 Represses Wnt/β-Catenin Signaling and Angiogenesis.
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| Jiang L, Yin M, Wei X, Liu J, Wang X, Niu C, Kang X, Xu J, Zhou Z, Sun S, Wang X, Zheng X, Duan S, Yao K, Qian R, Sun N, Chen A, Wang R, Zhang J, Chen S, Meng D.
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| Circ Res 117(4):364-75. doi: 10.1161/CIRCRESAHA.115.306829. Epub 2015 Jun 29. Erratum in: Circ Res. 2015 Oct 9;117(9):e79.
2015
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| 8 | BACH1, BACH2, EBF1
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| The transcription repressors Bach2 and Bach1 promote B cell development by repressing the myeloid program.
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| Itoh-Nakadai A, Hikota R, Muto A, Kometani K, Watanabe-Matsui M, Sato Y, Kobayashi M, Nakamura A, Miura Y, Yano Y, Tashiro S, Sun J, Ikawa T, Ochiai K, Kurosaki T, Igarashi K.
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| Nat Immunol 15(12):1171-80. doi: 10.1038/ni.3024. Epub 2014 Oct 26.
2014
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| 9 | BACH1
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| Hemopexin-dependent heme uptake via endocytosis regulates the Bach1 transcription repressor and heme oxygenase gene activation.
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| Hada H, Shiraki T, Watanabe-Matsui M, Igarashi K.
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| Biochim Biophys Acta 1840(7):2351-60. doi: 10.1016/j.bbagen.2014.02.029. Epub 2014 Mar 5.
2014
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| 10 | BACH1, MAFK, TGFB1
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| Transforming growth factor-β induces transcription factors MafK and Bach1 to suppress expression of the heme oxygenase-1 gene.
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| Okita Y, Kamoshida A, Suzuki H, Itoh K, Motohashi H, Igarashi K, Yamamoto M, Ogami T, Koinuma D, Kato M.
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| J Biol Chem 288(28):20658-67. doi: 10.1074/jbc.M113.450478. Epub 2013 Jun 4.
2013
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| 11 | BACH1, XPO1
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| Transcription-independent role of Bach1 in mitosis through a nuclear exporter Crm1-dependent mechanism.
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| Li J, Shiraki T, Igarashi K.
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| FEBS Lett 586(4):448-54. Epub 2012 Jan 28.
2012
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| 12 | BACH1
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| Transcriptional network analysis identifies BACH1 as a master regulator of breast cancer bone metastasis.
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| Liang Y, Wu H, Lei R, Chong RA, Wei Y, Lu X, Tagkopoulos I, Kung SY, Yang Q, Hu G, Kang Y.
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| J Biol Chem 287(40):33533-44. Epub 2012 Aug 8.
2012
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| 13 | BACH1
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| Bach1-mediated suppression of p53 is inhibited by p19(ARF) independently of MDM2.
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| Nishizawa H, Ota K, Dohi Y, Ikura T, Igarashi K.
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| Cancer Sci 103(5):897-903. doi: 10.1111/j.1349-7006.2012.02244.x. Epub 2012 Apr 11.
2012
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| 14 | BACH1, HMOX1
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| The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle.
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| Warnatz HJ, Schmidt D, Manke T, Piccini I, Sultan M, Borodina T, Balzereit D, Wruck W, Soldatov A, Vingron M, Lehrach H, Yaspo ML.
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| J Biol Chem 286(26):23521-32. Epub 2011 May 9.
2011
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| 15 | BACH1
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| Bach1-dependent and -independent regulation of heme oxygenase-1 in keratinocytes.
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| Okada S, Muto A, Ogawa E, Nakanome A, Katoh Y, Ikawa S, Aiba S, Igarashi K, Okuyama R.
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| J Biol Chem 285(31):23581-9. Epub 2010 May 25.
2010
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| 16 | BACH1
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| Expression of heme oxygenase-1 in human leukemic cells and its regulation by transcriptional repressor Bach1.
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| Miyazaki T, Kirino Y, Takeno M, Samukawa S, Hama M, Tanaka M, Yamaji S, Ueda A, Tomita N, Fujita H, Ishigatsubo Y.
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| Cancer Sci 101(6):1409-16. Epub 2010 Mar 2.PMID: 20345481 2010
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| 17 | BACH1
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| Crystal structure of the Bach1 BTB domain and its regulation of homodimerization.
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| Ito N, Watanabe-Matsui M, Igarashi K, Murayama K.
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| Genes Cells 14(2):167-78. Epub 2008 Jan 12.PMID: 19170764 2009
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| 18 | BACH1, HMOX1
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| BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite.
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| Reichard JF, Sartor MA, Puga A.
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| J Biol Chem 283(33):22363-70. Epub 2008 Jun 11.
2008
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| 19 | BACH1, TP53
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| Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin.
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| Dohi Y, Ikura T, Hoshikawa Y, Katoh Y, Ota K, Nakanome A, Muto A, Omura S, Ohta T, Ito A, Yoshida M, Noda T, Igarashi K.
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| Nat Struct Mol Biol 15(12):1246-54. Epub 2008 Nov 16.
2008
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| 20 | BACH1
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| Ablation of the bach1 gene leads to the suppression of atherosclerosis in bach1 and apolipoprotein E double knockout mice.
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| Watari Y, Yamamoto Y, Brydun A, Ishida T, Mito S, Yoshizumi M, Igarashi K, Chayama K, Ohshima T, Ozono R.
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| Hypertens Res 31(4):783-92.PMID: 18633191 2008
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| 21 | BACH1, NFE2L2
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| Heme oxygenase-1 induction by NRF2 requires inactivation of the transcriptional repressor BACH1.
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| Reichard JF, Motz GT, Puga A.
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| Nucleic Acids Res 35(21):7074-86. Epub 2007 Oct 16. 2007
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| 22 | GATA1, BACH1, SON, GABPA, C21orf66, RUNX1
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| Identification of distinct molecular phenotypes in acute megakaryoblastic leukemia by gene expression profiling.
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| Bourquin JP, Subramanian A, Langebrake C, Reinhardt D, Bernard O, Ballerini P, Baruchel A, Cave H, Dastugue N, Hasle H, Kaspers GL, Lessard M, Michaux L, Vyas P, van Wering E, Zwaan CM, Golub TR, Orkin SH.
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| Proc Natl Acad Sci U S A 103(9):3339-44. Epub 2006 Feb 21. 2006
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| 23 | BACH1, BRCA1
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| BACH1 is a DNA repair protein supporting BRCA1 damage response.
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| Peng M, Litman R, Jin Z, Fong G, Cantor SB.
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| Oncogene 25(15):2245-53. 2006
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| 24 | HMOX1, BACH1
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| Role of Bach-1 in regulation of heme oxygenase-1 in human liver cells: insights from studies with small interfering RNAS.
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| Shan Y, Lambrecht RW, Ghaziani T, Donohue SE, Bonkovsky HL.
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| J Biol Chem 279(50):51769-74. Epub 2004 Oct 1. 2004
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| 25 | BACH1, MAFK
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| Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network.
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| Sun J, Brand M, Zenke Y, Tashiro S, Groudine M, Igarashi K.
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| Proc Natl Acad Sci U S A 101(6):1461-6. Epub 2004 Jan 27.
2004
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| 26 | BACH1, BRCA1, BRIP1
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| BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function.
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| Cantor SB, Bell DW, Ganesan S, Kass EM, Drapkin R, Grossman S, Wahrer DC, Sgroi DC, Lane WS, Haber DA, Livingston DM.
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| Cell 105(1):149-60. 2001
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| 27 | BACH1
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| Transcription factor BACH1 is recruited to the nucleus by its novel alternative spliced isoform.
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| Kanezaki R, Toki T, Yokoyama M, Yomogida K, Sugiyama K, Yamamoto M, Igarashi K, Ito E.
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| J Biol Chem 276(10):7278-84. 2001
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| 28 | BACH1
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| Characterization of a human homolog (BACH1) of the mouse Bach1 gene encoding a BTB-basic leucine zipper transcription factor and its mapping to chromosome 21q22.1.
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| Ohira M, Seki N, Nagase T, Ishikawa K, Nomura N, Ohara O.
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| Genomics 47(2):300-6. 1998
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| 29 | BACH1
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| Isolation of the human BACH1 transcription regulator gene, which maps to chromosome 21q22.1.
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| Blouin JL, et al.
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| Hum Genet 102 : 282-288. 1998
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| 30 | BACH1
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| Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription throuth the NF-E2 site.
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| Oyake T, et al.
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| Mol Cell Biol 16 : 6083-6095. 1996
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| 31 | BACH1, BACH2
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| Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site.
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| Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa M, Yamamoto M, Igarashi K.
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| Mol Cell Biol 16(11):6083-95. 1996
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