Citations for
1AXIN2, HDAC3, RUNX2
Runx2 protein represses Axin2 expression in osteoblasts and is required for craniosynostosis in Axin2-deficient mice.
McGee-Lawrence ME, Li X, Bledsoe KL, Wu H, Hawse JR, Subramaniam M, Razidlo DF, Stensgard BA, Stein GS, van Wijnen AJ, Lian JB, Hsu W, Westendorf JJ.
J Biol Chem 288(8):5291-302. doi: 10.1074/jbc.M112.414995. Epub 2013 Jan 7. 2013
2AXIN2
Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity.
Wu ZQ, Brabletz T, Fearon E, Willis AL, Hu CY, Li XY, Weiss SJ.
Proc Natl Acad Sci U S A 109(28):11312-7. doi: 10.1073/pnas.1203015109. Epub 2012 Jun 27. 2012
3AXIN2, FOXM1, KRAS
Foxm1 mediates cross talk between Kras/mitogen-activated protein kinase and canonical Wnt pathways during development of respiratory epithelium.
Wang IC, Snyder J, Zhang Y, Lander J, Nakafuku Y, Lin J, Chen G, Kalin TV, Whitsett JA, Kalinichenko VV.
Mol Cell Biol 32(19):3838-50. doi: 10.1128/MCB.00355-12. Epub 2012 Jul 23. 2012
4AXIN2
Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination.
Fancy SP, Harrington EP, Yuen TJ, Silbereis JC, Zhao C, Baranzini SE, Bruce CC, Otero JJ, Huang EJ, Nusse R, Franklin RJ, Rowitch DH.
Nat Neurosci. 14(8):1009-16. 2011
5AXIN2, CEP250, CTNNB1
Conductin/axin2 and Wnt signalling regulates centrosome cohesion.
Hadjihannas MV, Brückner M, Behrens J.
EMBO Rep 11(4):317-24. Epub 2010 Mar 19.PMID: 20300119 2010
6AXIN1, AXIN2
Axin2 regulates chondrocyte maturation and axial skeletal development.
Dao DY, Yang X, Flick LM, Chen D, Hilton MJ, O'Keefe RJ.
J Orthop Res 28(1):89-95. 2010
7AXIN2, SOX5
SOX5 controls cell cycle progression in neural progenitors by interfering with the WNT-beta-catenin pathway.
Martinez-Morales PL, Quiroga AC, Barbas JA, Morales AV.
EMBO Rep 11(6):466-72. Epub 2010 May 7. 2010
8AXIN2, TCF7L2
Frameshift mutations of Wnt pathway genes AXIN2 and TCF7L2 in gastric carcinomas with high microsatellite instability.
Kim MS, Kim SS, Ahn CH, Yoo NJ, Lee SH.
Hum Pathol 40(1):58-64. Epub 2008 Aug 27.PMID: 18755497 2009
9AXIN2
AXIS inhibition protein 2, orofacial clefts and a family history of cancer.
Menezes R, Marazita ML, Goldstein McHenry T, Cooper ME, Bardi K, Brandon C, Letra A, Martin RA, Vieira AR.
J Am Dent Assoc 140(1):80-4.PMID: 19119171 2009
10AXIN2
[Association of single nucleotide polymorphisms of Axis inhibitor-2 gene rs224030, rs8081536, rs9913621 with Hirschsprung disease]
Gao H, Zhang J, Wang W, Zhang Z, Huang Y, Zhang S.
Zhonghua Yi Xue Yi Chuan Xue Za Zhi 25(6):697-700. Chinese. PMID: 19065536 2008
11AXIN2
Craniosynostosis caused by Axin2 deficiency is mediated through distinct functions of beta-catenin in proliferation and differentiation.
Liu B, Yu HM, Hsu W.
Dev Biol 301(1):298-308. Epub 2006 Oct 21. 2007
12AXIN2, MUTYH, FTACC
Low frequency of AXIN2 mutations and high frequency of MUTYH mutations in patients with multiple polyposis.
Lejeune S, Guillemot F, Triboulet JP, Cattan S, Mouton C; PAFNORD Group; Porchet N, Manouvrier S, Buisine MP.
Hum Mutat 27(10):1064. 2006
13APC, CTNNB1, WNT1, AXIN2
Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis.
Cho KH, Baek S, Sung MH.
FEBS Lett 580(15):3665-70. Epub 2006 Jun 5. 2006
14WNT1, AXIN2, SNAI1, GSK3B
A Wnt-Axin2-GSK3beta cascade regulates Snail1 activity in breast cancer cells.
Yook JI, Li XY, Ota I, Hu C, Kim HS, Kim NH, Cha SY, Ryu JK, Choi YJ, Kim J, Fearon ER, Weiss SJ.
Nat Cell Biol 8(12):1398-406. Epub 2006 Oct 29. 2006
15AXIN1, AXIN2, TCF7L2
Colorectal cancer and genetic alterations in the Wnt pathway.
Segditsas S, Tomlinson I.
Oncogene 25(57):7531-7. Review. 2006
16FTACC, AXIN2
Axis inhibition protein 2 (AXIN2) polymorphisms may be a risk factor for selective tooth agenesis.
Mostowska A, Biedziak B, Jagodzinski PP.
J Hum Genet 51(3):262-6. Epub 2006 Jan 24. 2006
17AXIN2
Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability.
Koinuma K, Yamashita Y, Liu W, Hatanaka H, Kurashina K, Wada T, Takada S, Kaneda R, Choi YL, Fujiwara SI, Miyakura Y, Nagai H, Mano H.
Oncogene. 25(1):139-46. 2006
18AXIN2, FTACC
Mutations in AXIN2 Cause Familial Tooth Agenesis and Predispose to Colorectal Cancer.
Lammi L, Arte S, Somer M, Jarvinen H, Lahermo P, Thesleff I, Pirinen S, Nieminen P.
Am J Hum Genet 74(5):1043-50. Epub 2004 Mar 23. 2004
19AXIN1, AXIN2
Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway.
Amit S, Hatzubai A, Birman Y, Andersen JS, Ben-Shushan E, Mann M, Ben-Neriah Y, Alkalay I.
Genes Dev 16(9):1066-76. 2002
20AXIN1, AXIN2, CDH1, CTNNA1, JUP
Cadherin and catenin alterations in human cancer.
Hajra KM, Fearon ER.
Genes Chromosomes Cancer 34(3):255-68. Review. 2002
21AXIN1, AXIN2
Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in hepatocellular carcinomas and hepatoblastomas.
Taniguchi K, Roberts LR, Aderca IN, Dong X, Qian C, Murphy LM, Nagorney DM, Burgart LJ, Roche PC, Smith DI, Ross JA, Liu W.
Oncogene 21(31):4863-71. 2002
22AXIN2
Genomic structure, chromosome mapping and expression analysis of the human AXIN2 gene.
Dong X, Seelan RS, Qian C, Mai M, Liu W.
Cytogenet Cell Genet 93(1-2):26-8. 2001
23AXIN2
Axin facilitates Smad3 activation in the transforming growth factor beta signaling pathway.
Furuhashi M, Yagi K, Yamamoto H, Furukawa Y, Shimada S, Nakamura Y, Kikuchi A, Miyazono K, Kato M.
Mol Cell Biol. 21(15):5132-41. 2001
24AXIN2
Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling.
Liu W, Dong X, Mai M, Seelan RS, Taniguchi K, Krishnadath KK, Halling KC, Cunningham JM, Qian C, Christensen E, Roche PC, Smith DI, Thibodeau SN.
Nat Genet 26(2):146-7. No abstract available. 2000
25AXIN2
Cloning of the human homolog of conductin (AXIN2), a gene mapping to chromosome 17q23-q24.
Mai M, et al.
Genomics 55(3):341-4. 1999
26AXIN1, AXIN2
Modulation of Wnt signaling by Axin and Axil.
Kikuchi A.
Cytokine Growth Factor Rev 10(3-4):255-65. 1999
27AXIN1, AXIN2
Functional domains of axin. Importance of the C terminus as an oligomerization domain.
Sakanaka C, Williams LT.
J Biol Chem 274(20):14090-3. 1999
28AXIN1, AXIN2, DVL1, DVL2, DVL3
DIX domains of Dvl and axin are necessary for protein interactions and their ability to regulate beta-catenin stability.
Kishida S, Yamamoto H, Hino S, Ikeda S, Kishida M, Kikuchi A.
Mol Cell Biol 19(6):4414-22. 1999
29AXIN2
Axil, a member of the Axin family, interacts with both glycogen synthase kinase 3beta and beta-catenin and inhibits axis formation of Xenopus embryos.
Yamamoto H, Kishida S, Uochi T, Ikeda S, Koyama S, Asashima M, Kikuchi A.
Mol Cell Biol. 18(5):2867-75. 1998