Citations for
1ATG10, ATG12, ATG16L1, ATG5
Functional variants of autophagy-related genes are associated with the development of hepatocellular carcinoma.
Shen M, Lin L.
Life Sci 235:116675. doi: 10.1016/j.lfs.2019.116675. Epub 2019 Jul 21. 2019
2ATG10, ATG12, ATG5, ATG7, IFNL2
Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine44 and Cysteine135.
Zhang MQ, Li JR, Peng ZG, Zhang JP.
Front Immunol 9:2176. doi: 10.3389/fimmu.2018.02176. eCollection 2018. 2018
3ATF4, ATG5
ATF4/ATG5 Signaling in Hypothalamic Proopiomelanocortin Neurons Regulates Fat Mass via Affecting Energy Expenditure.
Xiao Y, Deng Y, Yuan F, Xia T, Liu H, Li Z, Liu Z, Ying H, Liu Y, Zhai Q, Chen S, Guo F.
Diabetes 66(5):1146-1158. doi: 10.2337/db16-1546. Epub 2017 Feb 17. 2017
4ATG5, ATG7
Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine.
Su LY, Luo R, Liu Q, Su JR, Yang LX, Ding YQ, Xu L, Yao YG.
Autophagy 13(9):1496-1511. doi: 10.1080/15548627.2017.1332549. Epub 2017 Jul 19. 2017
5ATG5
Aging-related Atg5 defect impairs neutrophil extracellular traps formation.
Xu F, Zhang C, Zou Z, Fan EKY, Chen L, Li Y, Billiar TR, Wilson MA, Shi X, Fan J.
Immunology 151(4):417-432. doi: 10.1111/imm.12740. Epub 2017 May 16. 2017
6ATG5, BSN
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC.
Neuron 93(4):897-913.e7. doi: 10.1016/j.neuron.2017.01.026. Erratum in: Neuron. 2018 Feb 7;97(3):727. 2017
7ATG5, SCAR25
Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay.
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, Schulman BA, Xu J, Semple I, Ro SH, Kim B, Mavioglu RN, Tolun A, Jipa A, Takats S, Karpati M, Li JZ, Yapici Z, Juhasz G, Lee JH, Klionsky DJ, Burmeister M.
Elife 5. pii: e12245. doi: 10.7554/eLife.12245. 2016
8ATG12, ATG16L1, ATG5, RACK1
RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy.
Erbil S, Oral O, Mitou G, Kig C, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik D.
J Biol Chem 291(32):16753-65. doi: 10.1074/jbc.M115.708081. Epub 2016 Jun 20. 2016
9ATG5
Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis.
Li H, Peng X, Wang Y, Cao S, Xiong L, Fan J, Wang Y, Zhuang S, Yu X, Mao H.
Autophagy 12(9):1472-86. doi: 10.1080/15548627.2016.1190071. Epub 2016 Jun 15. 2016
10ATG16L1, ATG5, TECPR1
Swapping of interaction partners with ATG5 for autophagosome maturation.
Kim JH, Song HK.
BMB Rep 48(3):129-30. 2015
11ATG12, ATG16L1, ATG5, TECPR1
Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners.
Kim JH, Hong SB, Lee JK, Han S, Roh KH, Lee KE, Kim YK, Choi EJ, Song HK.
Autophagy 11(1):75-87. doi: 10.4161/15548627.2014.984276. 2015
12ATG5, MUL1, ULK1
Mitochondrial outer-membrane E3 ligase MUL1 ubiquitinates ULK1 and regulates selenite-induced mitophagy.
Li J, Qi W, Chen G, Feng D, Liu J, Ma B, Zhou C, Mu C, Zhang W, Chen Q, Zhu Y.
Autophagy 11(8):1216-29. doi: 10.1080/15548627.2015.1017180. 2015
13ATG5, ELAVL4
The RNA-binding protein HuD regulates autophagosome formation in pancreatic β cells by promoting autophagy-related gene 5 expression.
Kim C, Kim W, Lee H, Ji E, Choe YJ, Martindale JL, Akamatsu W, Okano H, Kim HS, Nam SW, Gorospe M, Lee EK.
J Biol Chem 289(1):112-21. doi: 10.1074/jbc.M113.474700. Epub 2013 Nov 25. 2014
14ATG5
Dynamic involvement of ATG5 in cellular stress responses.
Lin HH, Lin SM, Chung Y, Vonderfecht S, Camden JM, Flodby P, Borok Z, Limesand KH, Mizushima N, Ann DK.
Cell Death Dis 5:e1478. doi: 10.1038/cddis.2014.428. 2014
15ATG5
Autophagy-related gene Atg5 is essential for astrocyte differentiation in the developing mouse cortex.
Wang S, Li B, Qiao H, Lv X, Liang Q, Shi Z, Xia W, Ji F, Jiao J.
EMBO Rep 15(10):1053-61. doi: 10.15252/embr.201338343. Epub 2014 Sep 15. 2014
16ATG5
The crucial role of Atg5 in cortical neurogenesis during early brain development.
Lv X, Jiang H, Li B, Liang Q, Wang S, Zhao Q, Jiao J.
Sci Rep 4:6010. doi: 10.1038/srep06010. 2014
17ATG5
Autophagy is essential for cardiac morphogenesis during vertebrate development.
Lee E, Koo Y, Ng A, Wei Y, Luby-Phelps K, Juraszek A, Xavier RJ, Cleaver O, Levine B, Amatruda JF.
Autophagy 10(4):572-87. doi: 10.4161/auto.27649. Epub 2014 Jan 14. 2014
18ATG5, MYD88
Atg5 regulates formation of MyD88 condensed structures and MyD88-dependent signal transduction.
Inomata M, Into T, Niida S, Murakami Y.
Biochem Biophys Res Commun 437(4):509-14. doi: 10.1016/j.bbrc.2013.06.094. Epub 2013 Jul 2. 2013
19ATG5
ATG5 is induced by DNA-damaging agents and promotes mitotic catastrophe independent of autophagy.
Maskey D, Yousefi S, Schmid I, Zlobec I, Perren A, Friis R, Simon HU.
Nat Commun 4:2130. doi: 10.1038/ncomms3130. 2013
20ATG12, ATG5, MAP1LC3B
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan.
Mai S, Muster B, Bereiter-Hahn J, Jendrach M.
Autophagy 8(1):47-62. doi: 10.4161/auto.8.1.18174. Epub 2012 Jan 1. 2012
21ATG12, ATG5, TECPR1
A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.
Chen D, Fan W, Lu Y, Ding X, Chen S, Zhong Q.
Mol Cell 45(5):629-41. doi: 10.1016/j.molcel.2011.12.036. Epub 2012 Feb 16. 2012
22ATG10, ATG12, ATG5, ATG7
Structure of the autophagic E2 enzyme Atg10.
Hong SB, Kim BW, Kim JH, Song HK.
Acta Crystallogr D Biol Crystallogr 68(Pt 10):1409-17. Epub 2012 Sep 18. 2012
23ATG5, TECPR1
The role of Tecpr1 in selective autophagy as a cargo receptor.
Ogawa M, Sasakawa C.
Autophagy 7(11):1389-91. doi: 10.4161/auto.7.11.17151. Epub 2011 Nov 1. 2011
24ATG5, MAP1LC3B
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5.
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, Savelkouls K, Keulers T, Mujcic H, Landuyt W, Voncken JW, Lambin P, van der Kogel AJ, Koritzinsky M, Wouters BG.
J Clin Invest 120(1):127-41. doi: 10.1172/JCI40027. Epub 2009 Dec 14. 2010
25ATG5
In vivo requirement for Atg5 in antigen presentation by dendritic cells.
Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A.
Immunity 32(2):227-39. Epub 2010 Feb 18.PMID: 20171125 2010
26ATG12, ATG3, ATG5
ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.
Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C, Debnath J.
Cell 142(4):590-600. 2010
27ATG5, ATG7
Discovery of Atg5/Atg7-independent alternative macroautophagy.
Nishida Y, Arakawa S, Fujitani K, Yamaguchi H, Mizuta T, Kanaseki T, Komatsu M, Otsu K, Tsujimoto Y, Shimizu S.
Nature 461(7264):654-8.PMID: 19794493 2009
28ATG5
Targeted deletion of autophagy-related 5 (atg5) impairs adipogenesis in a cellular model and in mice.
Baerga R, Zhang Y, Chen PH, Goldman S, Jin S.
Autophagy 5(8):1118-30. Epub 2009 Nov 2.PMID: 19844159 2009
29ATG5
Identification of Atg5-dependent transcriptional changes and increases in mitochondrial mass in Atg5-deficient T lymphocytes.
Stephenson LM, Miller BC, Ng A, Eisenberg J, Zhao Z, Cadwell K, Graham DB, Mizushima NN, Xavier R, Virgin HW, Swat W.
Autophagy 5(5):625-35. Epub 2009 Jul 10.PMID: 19276668 2009
30ATG5
Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis.
Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb AL, Frausto RF, Bhan V, Kiosses WB, Whitton JL, Robertson GS, Crocker SJ.
Autophagy 5(2):152-8. Epub 2009 Feb 5.PMID: 19066443 2009
31ATG12, ATG2B, ATG5, ATG9B
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, Ahn CH, Yoo NJ, Lee SH.
J Pathol 217(5):702-6.PMID: 19197948 2009
32ATG5, CASP8, FADD
FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells.
Bell BD, Leverrier S, Weist BM, Newton RH, Arechiga AF, Luhrs KA, Morrissette NS, Walsh CM.
Proc Natl Acad Sci U S A 105(43):16677-82. Epub 2008 Oct 22. 2008
33ATG5
The autophagy gene ATG5 plays an essential role in B lymphocyte development.
Miller BC, Zhao Z, Stephenson LM, Cadwell K, Pua HH, Lee HK, Mizushima NN, Iwasaki A, He YW, Swat W, Virgin HW 4th.
Autophagy 4(3):309-14. Epub 2007 Dec 24.PMID: 18188005 2008
34ATG16L1, ATG5
Structure of Atg5.Atg16, a complex essential for autophagy.
Matsushita M, Suzuki NN, Obara K, Fujioka Y, Ohsumi Y, Inagaki F.
J Biol Chem 282(9):6763-72. Epub 2006 Dec 27.PMID: 17192262 2007
35ATG12, ATG5, GABARAPL2
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.
J Biol Chem 282(52):37298-302. Epub 2007 Nov 6.PMID: 17986448 2007
36ATG12, ATG5
The Atg5 Atg12 conjugate associates with innate antiviral immune responses.
Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, Okuda K.
Proc Natl Acad Sci U S A 104(35):14050-5. Epub 2007 Aug 20.PMID: 17709747 2007
37ATG5
[Bioinformatics analysis of autophagy 5 gene structure]
Chen Y, Peng XZ, Piao YJ.
Yi Chuan Xue Bao 28(11):1077-84. Chinese. 2001
38ATG5
Assignment(1) of the yeast APG5 human homologue APG5L to chromosome band 6q21 by fluorescence in situ hybridisation.
Schmeiser K, Armstrong S, Hammond EM, Grand RJ.
Cytogenet Cell Genet 87(3-4):213-214. 1999
39ATG5
Homology between a human apoptosis specific protein and the product of APG5, a gene involved in autophagy in yeast.
Hammond EM, et al.
FEBS Lett 425(3):391-5 1998
40ATG12, ATG5
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
Mizushima N, et al.
J Biol Chem 273(51):33889-92 1998