Citations for
1ATG10, ATG12, ATG16L1, ATG5
Functional variants of autophagy-related genes are associated with the development of hepatocellular carcinoma.
Shen M, Lin L.
Life Sci 235:116675. doi: 10.1016/j.lfs.2019.116675. Epub 2019 Jul 21. 2019
2ATG10, ATG12, ATG5, ATG7, IFNL2
Differential Effects of Autophagy-Related 10 Protein on HCV Replication and Autophagy Flux Are Mediated by Its Cysteine44 and Cysteine135.
Zhang MQ, Li JR, Peng ZG, Zhang JP.
Front Immunol 9:2176. doi: 10.3389/fimmu.2018.02176. eCollection 2018. 2018
3ATG12, ATG16L1, ATG5, RACK1
RACK1 Is an Interaction Partner of ATG5 and a Novel Regulator of Autophagy.
Erbil S, Oral O, Mitou G, Kig C, Durmaz-Timucin E, Guven-Maiorov E, Gulacti F, Gokce G, Dengjel J, Sezerman OU, Gozuacik D.
J Biol Chem 291(32):16753-65. doi: 10.1074/jbc.M115.708081. Epub 2016 Jun 20. 2016
Insights into autophagosome maturation revealed by the structures of ATG5 with its interacting partners.
Kim JH, Hong SB, Lee JK, Han S, Roh KH, Lee KE, Kim YK, Choi EJ, Song HK.
Autophagy 11(1):75-87. doi: 10.4161/15548627.2014.984276. 2015
Autophagy proteins LC3B, ATG5 and ATG12 participate in quality control after mitochondrial damage and influence lifespan.
Mai S, Muster B, Bereiter-Hahn J, Jendrach M.
Autophagy 8(1):47-62. doi: 10.4161/auto.8.1.18174. Epub 2012 Jan 1. 2012
A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate.
Chen D, Fan W, Lu Y, Ding X, Chen S, Zhong Q.
Mol Cell 45(5):629-41. doi: 10.1016/j.molcel.2011.12.036. Epub 2012 Feb 16. 2012
7ATG10, ATG12, ATG5, ATG7
Structure of the autophagic E2 enzyme Atg10.
Hong SB, Kim BW, Kim JH, Song HK.
Acta Crystallogr D Biol Crystallogr 68(Pt 10):1409-17. Epub 2012 Sep 18. 2012
8ATG12, BCL2, MCL1
The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis.
Rubinstein AD, Eisenstein M, Ber Y, Bialik S, Kimchi A.
Mol Cell 44(5):698-709. doi: 10.1016/j.molcel.2011.10.014. 2011
9ATG12, ATG3, ATG5
ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death.
Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C, Debnath J.
Cell 142(4):590-600. 2010
Frameshift mutations of autophagy-related genes ATG2B, ATG5, ATG9B and ATG12 in gastric and colorectal cancers with microsatellite instability.
Kang MR, Kim MS, Oh JE, Kim YR, Song SY, Kim SS, Ahn CH, Yoo NJ, Lee SH.
J Pathol 217(5):702-6.PMID: 19197948 2009
The Atg12-Atg5 conjugate has a novel E3-like activity for protein lipidation in autophagy.
Hanada T, Noda NN, Satomi Y, Ichimura Y, Fujioka Y, Takao T, Inagaki F, Ohsumi Y.
J Biol Chem 282(52):37298-302. Epub 2007 Nov 6.PMID: 17986448 2007
12ATG12, ATG5
The Atg5 Atg12 conjugate associates with innate antiviral immune responses.
Jounai N, Takeshita F, Kobiyama K, Sawano A, Miyawaki A, Xin KQ, Ishii KJ, Kawai T, Akira S, Suzuki K, Okuda K.
Proc Natl Acad Sci U S A 104(35):14050-5. Epub 2007 Aug 20.PMID: 17709747 2007
Mitochondrial DNA deletions and chloramphenicol treatment stimulate the autophagic transcript ATG12.
Prigione A, Cortopassi G.
Autophagy 3(4):377-80. Epub 2007 Jul 5.PMID: 17457038 2007
Structure-function relationship of Atg12, a ubiquitin-like modifier essential for autophagy.
Hanada T, Ohsumi Y.
Autophagy 1(2):110-8. Epub 2005 Jul 23.PMID: 16874032 2005
The human homolog of Saccharomyces cerevisiae Apg7p is a Protein-activating enzyme for multiple substrates including human Apg12p, GATE-16, GABARAP, and MAP-LC3.
Tanida I, Tanida-Miyake E, Ueno T, Kominami E.
J Biol Chem 276(3):1701-6. 2001
16ATG12, ATG5
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
Mizushima N, et al.
J Biol Chem 273(51):33889-92 1998
17ATG12, COL1A1, NID2
Nidogen-2: a new basement membrane protein with diverse binding properties.
Kohfeldt E, Sasaki T, Gohring W, Timpl R.
J Mol Biol 282(1):99-109. 1998
A protein conjugation system essential for autophagy.
Mizushima N, Noda T, Yoshimori T, Tanaka Y, Ishii T, George MD, Klionsky DJ, Ohsumi M, Ohsumi Y.
Nature 395(6700):395-8. 1998
Cloning and tissue expression of cDNAs from chromosome 5q21-22 which is frequently deleted in advanced lung cancer.
Ueno K, Kumagai T, Kijima T, Kishimoto T, Hosoe S.
Hum Genet 102(1):63-8. 1998