| 1 | ATE1
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| Posttranslational Arginylation Enzyme Arginyltransferase1 Shows Genetic Interactions With Specific Cellular Pathways in vivo.
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| Wiley DJ, D'Urso G, Zhang F.
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| Front Physiol. May 6;11:427. doi: 10.3389/fphys.2020.00427. eCollection 2020 2020
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| 2 | ATE1
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| Reduced Arginyltransferase 1 is a driver and a potential prognostic indicator of prostate cancer metastasis.
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| Birnbaum MD, Zhao N, Moorthy BT, Patel DM, Kryvenko ON, Heidman L, Kumar A, Morgan WM, Ban Y, Reis IM, Chen X, Gonzalgo ML, Jorda M, Burnstein KL, Zhang F.
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| Oncogene Feb;38(6):838-851. doi: 10.1038/s41388-018-0462-2. Epub 2018 Sep 3 2019
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| 3 | ATE1, HSPA5
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| The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation.
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| Shim SM, Choi HR, Sung KW, Lee YJ, Kim ST, Kim D, Mun SR, Hwang J, Cha-Molstad H, Ciechanover A, Kim BY, Kwon YT.
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| Sci Signal. Jan 2;11(511):eaan0630. doi: 10.1126/scisignal.aan0630 2018
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| 4 | ATE1
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| Arginyltransferase ATE1 is targeted to the neuronal growth cones and regulates neurite outgrowth during brain development.
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| Wang J, Pavlyk I, Vedula P, Sterling S, Leu NA, Dong DW, Kashina A.
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| Dev Biol. Oct 1;430(1):41-51. doi: 10.1016/j.ydbio.2017.08.027. Epub 2017 Aug 26 2017
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| 5 | ATE1
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| Posttranslational arginylation enzyme Ate1 affects DNA mutagenesis by regulating stress response.
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| Kumar A, Birnbaum MD, Patel DM, Morgan WM, Singh J, Barrientos A, Zhang F.
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| Cell Death Dis. Sep 29;7(9):e2378. doi: 10.1038/cddis.2016.284 2016
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| 6 | ATE1, RGS4
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| Ablation of Arg-tRNA-protein transferases results in defective neural tube development.
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| Kim E, Kim S, Lee JH, Kwon YT, Lee MJ.
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| BMB Rep. Aug;49(8):443-8. doi: 10.5483/bmbrep.2016.49.8.087 2016
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| 7 | ATE1
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| Post-translational protein arginylation in the normal nervous system and in neurodegeneration.
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| Galiano MR, Goitea VE, Hallak ME.
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| J Neurochem. Aug;138(4):506-17. doi: 10.1111/jnc.13708. Epub 2016 Jul 5 2016
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| 8 | ATE1, DELQ10D, FGFR2, NSMCE4A, WDR11
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| 10q26.1 Microdeletion: Redefining the critical regions for microcephaly and genital anomalies.
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| Choucair N, Abou Ghoch J, Fawaz A, Mégarbané A, Chouery E.
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| Am J Med Genet A 167A(11):2707-13. doi: 10.1002/ajmg.a.37211. Epub 2015 Jun 26.
2015
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| 9 | ATE1, HSPA5
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| Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
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| Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT.
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| Nat Cell Biol. Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15 2015
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| 10 | ATE1
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| Arginyltransferase ATE1 catalyzes midchain arginylation of proteins at side chain carboxylates in vivo.
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| Wang J, Han X, Wong CC, Cheng H, Aslanian A, Xu T, Leavis P, Roder H, Hedstrom L, Yates JR 3rd, Kashina A.
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| Chem Biol. Mar 20;21(3):331-7. doi: 10.1016/j.chembiol.2013.12.017. Epub 2014 Feb 13 2014
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| 11 | ATE1
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| Loss of ATE1-mediated arginylation leads to impaired platelet myosin phosphorylation, clot retraction, and in vivo thrombosis formation.
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| Lian L, Suzuki A, Hayes V, Saha S, Han X, Xu T, Yates JR 3rd, Poncz M, Kashina A, Abrams CS.
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| Haematologica Mar;99(3):554-60. doi: 10.3324/haematol.2013.093047. Epub 2013 Nov 29 2014
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| 12 | ATE1, C17orf97
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| Liat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeats.
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| Brower CS, Rosen CE, Jones RH, Wadas BC, Piatkov KI, Varshavsky A.
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| Proc Natl Acad Sci U S A Nov 18;111(46):E4936-45. doi: 10.1073/pnas.1419587111. Epub 2014 Nov 4 2014
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| 13 | ATE1, MRTFA
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| Inhibition of arginyltransferase 1 induces transcriptional activity of myocardin-related transcription factor A (MRTF-A) and promotes directional migration.
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| Eisenach PA, Schikora F, Posern G.
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| J Biol Chem. Dec 19;289(51):35376-87. doi: 10.1074/jbc.M114.578674. Epub 2014 Nov 7 2014
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| 14 | ATE1
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| Small molecule inhibitors of arginyltransferase regulate arginylation-dependent protein degradation, cell motility, and angiogenesis.
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| Saha S, Wang J, Buckley B, Wang Q, Lilly B, Chernov M, Kashina A.
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| Biochem Pharmacol. Apr 1;83(7):866-73. doi: 10.1016/j.bcp.2012.01.012. Epub 2012 Jan 18 2012
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| 15 | ATE1
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| Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes.
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| Lee MJ, Kim DE, Zakrzewska A, Yoo YD, Kim SH, Kim ST, Seo JW, Lee YS, Dorn GW 2nd, Oh U, Kim BY, Kwon YT.
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| J Biol Chem. Jul 6;287(28):24043-52. doi: 10.1074/jbc.M112.364117. Epub 2012 May 10 2012
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| 16 | ATE1
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| Arginyltransferase regulates alpha cardiac actin function, myofibril formation and contractility during heart development.
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| Rai R, Wong CC, Xu T, Leu NA, Dong DW, Guo C, McLaughlin KJ, Yates JR 3rd, Kashina A.
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| Development Dec;135(23):3881-9. doi: 10.1242/dev.022723. Epub 2008 Oct 23 2008
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| 17 | ATE1, HSPA5
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| Arginyltransferase, its specificity, putative substrates, bidirectional promoter, and splicing-derived isoforms.
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| Hu RG, Brower CS, Wang H, Davydov IV, Sheng J, Zhou J, Kwon YT, Varshavsky A.
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| J Biol Chem. Oct 27;281(43):32559-73. doi: 10.1074/jbc.M604355200. Epub 2006 Aug 30 2006
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| 18 | ATE1
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| Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway.
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| Kwon YT, Kashina AS, Varshavsky A.
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| Mol Cell Biol 19(1):182-93. 1999
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