| 1 | ASXL1, ASXL2, ASXL3, BAP1
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| BAP1/ASXL1 recruitment and activation for H2A deubiquitination.
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| Sahtoe DD, van Dijk WJ, Ekkebus R, Ovaa H, Sixma TK.
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| Nat Commun 7:10292. doi: 10.1038/ncomms10292.
2016
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| 2 | ASXL1, ASXL2, ASXL3
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| Unlike ASXL1 and ASXL2 mutations, ASXL3 mutations are rare events in acute myeloid leukemia with t(8;21).
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| Duployez N, Micol JB, Boissel N, Petit A, Geffroy S, Bucci M, Lapillonne H, Renneville A, Leverger G, Ifrah N, Dombret H, Abdel-Wahab O, Jourdan E, Preudhomme C.
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| Leuk Lymphoma 57(1):199-200. doi: 10.3109/10428194.2015.1037754. No abstract available.
2016
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| 3 | ASXL1
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| Dynamic ASXL1 Exon Skipping and Alternative Circular Splicing in Single Human Cells.
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| Koh W, Gonzalez V, Natarajan S, Carter R, Brown PO, Gawad C.
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| PLoS One 11(10):e0164085. doi: 10.1371/journal.pone.0164085.
2016
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| 4 | ASXL1, BOPS
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| Screening of CD96 and ASXL1 in 11 patients with Opitz C or Bohring-Opitz syndromes.
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| Urreizti R, Roca-Ayats N, Trepat J, Garcia-Garcia F, Aleman A, Orteschi D, Marangi G, Neri G, Opitz JM, Dopazo J, Cormand B, Vilageliu L, Balcells S, Grinberg D.
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| Am J Med Genet A 170A(1):24-31. doi: 10.1002/ajmg.a.37418.
2016
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| 5 | ASXL1, SETBP1
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| ASXL1 mutations are frequent and prognostically detrimental in CSF3R-mutated chronic neutrophilic leukemia.
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| Elliott MA, Pardanani A, Hanson CA, Lasho TL, Finke CM, Belachew AA, Tefferi A.
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| Am J Hematol 90(7):653-6. doi: 10.1002/ajh.24031.
2015
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| 6 | ASXL1, SETBP1
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| SETBP1 mutations drive leukemic transformation in ASXL1-mutated MDS.
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| Inoue D, Kitaura J, Matsui H, Hou HA, Chou WC, Nagamachi A, Kawabata KC, Togami K, Nagase R, Horikawa S, Saika M, Micol JB, Hayashi Y, Harada Y, Harada H, Inaba T, Tien HF, Abdel-Wahab O, Kitamura T.
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| Leukemia 29(4):847-57. doi: 10.1038/leu.2014.301. Epub 2014 Oct 13.
2015
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| 7 | ASXL1, ASXL2, BAP1
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| The BAP1/ASXL2 Histone H2A Deubiquitinase Complex Regulates Cell Proliferation and Is Disrupted in Cancer.
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| Daou S, Hammond-Martel I, Mashtalir N, Barbour H, Gagnon J, Iannantuono NV, Nkwe NS, Motorina A, Pak H, Yu H, Wurtele H, Milot E, Mallette FA, Carbone M, Affar el B.
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| J Biol Chem 290(48):28643-63. doi: 10.1074/jbc.M115.661553.
2015
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| 8 | ASXL1, CDKN2B
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| Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals.
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| Wu X, Bekker-Jensen IH, Christensen J, Rasmussen KD, Sidoli S, Qi Y, Kong Y, Wang X, Cui Y, Xiao Z, Xu G, Williams K, Rappsilber J, Sønderby CK, Winther O, Jensen ON, Helin K.
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| Cell Res 25(11):1205-18. doi: 10.1038/cr.2015.121.
2015
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| 9 | ASXL1
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| Role of Asxl1 in kidney podocyte development via its interaction with Wtip.
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| Moon S, Um SJ, Kim EJ.
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| Biochem Biophys Res Commun 466(3):560-6. doi: 10.1016/j.bbrc.2015.09.077.
2015
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| 10 | ASXL1, TET2
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| Mutations of ASXL1 and TET2 in aplastic anemia.
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| Huang J, Ge M, Lu S, Shi J, Li X, Zhang J, Wang M, Yu W, Shao Y, Huang Z, Zhang J, Nie N, Zheng Y.
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| Haematologica 100(5):e172-5. doi: 10.3324/haematol.2014.120931. No abstract available.
2015
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| 11 | ASXL1, CSF3R, SETBP1
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| ASXL1 mutations are frequent and prognostically detrimental in CSF3R-mutated chronic neutrophilic leukemia.
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| Elliott MA, Pardanani A, Hanson CA, Lasho TL, Finke CM, Belachew AA, Tefferi A.
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| Am J Hematol 90(7):653-6. doi: 10.1002/ajh.24031.
2015
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| 12 | ASXL1, ASXL2
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| Additional sex combs-like family genes are required for normal cardiovascular development.
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| McGinley AL, Li Y, Deliu Z, Wang QT.
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| Genesis 52(7):671-86. doi: 10.1002/dvg.22793.
2014
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| 13 | ASXL1, ASXL2, NR1H3
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| Reciprocal regulation of LXRα activity by ASXL1 and ASXL2 in lipogenesis.
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| Park UH, Seong MR, Kim EJ, Hur W, Kim SW, Yoon SK, Um SJ.
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| Biochem Biophys Res Commun 443(2):489-94. doi: 10.1016/j.bbrc.2013.11.124.
2014
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| 14 | ASXL1
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| Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice.
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| Wang J, Li Z, He Y, Pan F, Chen S, Rhodes S, Nguyen L, Yuan J, Jiang L, Yang X, Weeks O, Liu Z, Zhou J, Ni H, Cai CL, Xu M, Yang FC.
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| Blood 123(4):541-53. doi: 10.1182/blood-2013-05-500272.
2014
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| 15 | ASXL1, ASXL3, BOPS, BRPS
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| Expanding our knowledge of conditions associated with the ASXL gene family.
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| Russell B, Graham JM Jr.
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| Genome Med 5(2):16. doi: 10.1186/gm420.
2013
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| 16 | ASXL1
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| Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo.
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| Abdel-Wahab O, Gao J, Adli M, Dey A, Trimarchi T, Chung YR, Kuscu C, Hricik T, Ndiaye-Lobry D, Lafave LM, Koche R, Shih AH, Guryanova OA, Kim E, Li S, Pandey S, Shin JY, Telis L, Liu J, Bhatt PK, Monette S, Zhao X, Mason CE, Park CY, Bernstein BE, Aifantis I, Levine RL.
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| J Exp Med 210(12):2641-59. doi: 10.1084/jem.20131141.
2013
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| 17 | ASXL1, BOPS
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| Two novel patients with Bohring-Opitz syndrome caused by de novo ASXL1 mutations.
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| Magini P, Monica MD, Uzielli ML, Mongelli P, Scarselli G, Gambineri E, Scarano G, Seri M.
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| Am J Med Genet A 158A(4):917-21. doi: 10.1002/ajmg.a.35265. Epub 2012 Mar 14.
2012
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| 18 | ASXL1, TET2
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| Role of TET2 and ASXL1 mutations in the pathogenesis of myeloproliferative neoplasms.
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| Abdel-Wahab O, Tefferi A, Levine RL.
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| Hematol Oncol Clin North Am 26(5):1053-64. doi: 10.1016/j.hoc.2012.07.006. Review.
2012
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| 19 | ASXL1, SOX2
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| Positive regulation of additional sex comb-like 1 gene expression by the pluripotency factor SOX2.
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| Kang M, Lee SW, Kim EJ, Um SJ.
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| Biochem Biophys Res Commun 421(3):621-6. doi: 10.1016/j.bbrc.2012.04.072.
2012
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| 20 | ASXL1
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| ASXL1 mutations in primary and secondary myelofibrosis.
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| Ricci C, Spinelli O, Salmoiraghi S, Finazzi G, Carobbio A, Rambaldi A.
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| Br J Haematol 156(3):404-7. doi: 10.1111/j.1365-2141.2011.08865.x. No abstract available.
2012
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| 21 | ASXL1, ASXL2, ASXL3
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| Additional sex comb-like (ASXL) proteins 1 and 2 play opposite roles in adipogenesis via reciprocal regulation of peroxisome proliferator-activated receptor {gamma}.
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| Park UH, Yoon SK, Park T, Kim EJ, Um SJ.
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| J Biol Chem 286(2):1354-63. Epub 2010 Nov 3. 2011
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| 22 | ASXL1, BAP1, HCFC1
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| The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma.
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| Bott M, Brevet M, Taylor BS, Shimizu S, Ito T, Wang L, Creaney J, Lake RA, Zakowski MF, Reva B, Sander C, Delsite R, Powell S, Zhou Q, Shen R, Olshen A, Rusch V, Ladanyi M.
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| Nat Genet 43(7):668-72. doi: 10.1038/ng.855.
2011
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| 23 | ASXL1, BOPS
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| De novo nonsense mutations in ASXL1 cause Bohring-Opitz syndrome.
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| Hoischen A, van Bon BW, Rodríguez-Santiago B, Gilissen C, Vissers LE, de Vries P, Janssen I, van Lier B, Hastings R, Smithson SF, Newbury-Ecob R, Kjaergaard S, Goodship J, McGowan R, Bartholdi D, Rauch A, Peippo M, Cobben JM, Wieczorek D, Gillessen-Kaesbach G, Veltman JA, Brunner HG, de Vries BB.
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| Nat Genet 43(8):729-31. doi: 10.1038/ng.868.
2011
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| 24 | ASXL1, CBX5, KDM1A
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| ASXL1 represses retinoic acid receptor-mediated transcription through associating with HP1 and LSD1.
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| Lee SW, Cho YS, Na JM, Park UH, Kang M, Kim EJ, Um SJ.
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| J Biol Chem 285(1):18-29. Epub 2009 Oct 31.PMID: 19880879 2010
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| 25 | ASXL1
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| Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia.
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| Boultwood J, Perry J, Pellagatti A, Fernandez-Mercado M, Fernandez-Santamaria C, Calasanz MJ, Larrayoz MJ, Garcia-Delgado M, Giagounidis A, Malcovati L, Della Porta MG, Jädersten M, Killick S, Hellström-Lindberg E, Cazzola M, Wainscoat JS.
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| Leukemia 24(5):1062-5. Epub 2010 Feb 25. No abstract available. PMID: 2018246 2010
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| 26 | ASXL1
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| Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia.
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| Fisher CL, Pineault N, Brookes C, Helgason CD, Ohta H, Bodner C, Hess JL, Humphries RK, Brock HW.
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| Blood 115(1):38-46. Epub 2009 Oct 27.PMID: 19861679 2010
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| 27 | ASXL1
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| Distinct clinical and biological features of de novo acute myeloid leukemia with additional sex comb-like 1 (ASXL1) mutations.
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| Chou WC, Huang HH, Hou HA, Chen CY, Tang JL, Yao M, Tsay W, Ko BS, Wu SJ, Huang SY, Hsu SC, Chen YC, Huang YN, Chang YC, Lee FY, Liu MC, Liu CW, Tseng MH, Huang CF, Tien HF.
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| Blood 116(20):4086-94. Epub 2010 Aug 6.
2010
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| 28 | ASXL1, PAX5
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| Heterogeneous breakpoints in patients with acute lymphoblastic leukemia and the dic(9;20)(p11-13;q11) show recurrent involvement of genes at 20q11.21.
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| An Q, Wright SL, Moorman AV, Parker H, Griffiths M, Ross FM, Davies T, Harrison CJ, Strefford JC.
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| Haematologica 94(8):1164-9. Epub 2009 Jul 7.PMID: 19586940 2009
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| 29 | ASXL1
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| Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia.
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| Gelsi-Boyer V, Trouplin V, Adélaïde J, Bonansea J, Cervera N, Carbuccia N, Lagarde A, Prebet T, Nezri M, Sainty D, Olschwang S, Xerri L, Chaffanet M, Mozziconacci MJ, Vey N, Birnbaum D.
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| Br J Haematol 145(6):788-800. Epub 2009 Apr 15.PMID: 19388938 2009
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| 30 | ASXL1, ASXL2, ASXL3
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| Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family.
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| Fisher CL, Randazzo F, Humphries RK, Brock HW.
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| Gene 369:109-18. Epub 2006 Jan 18.PMID: 16412590 2006
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| 31 | ASXL3, ASXL1, ASXL2
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| Identification and characterization of ASXL3 gene in silico.
|
| Katoh M, Katoh M.
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| Int J Oncol 24(6):1617-22. 2004
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| 32 | ASXL1, ASXL2
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| Identification and characterization of ASXL2 gene in silico.
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| Katoh M, Katoh M.
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| Int J Oncol 23(3):845-50. 2003
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| 33 | AKAP2, AMOTL2, ANKRD6, ARSG, ASXL1, ATG4B, BAHD1, BIRC6, BTBD3, C6orf84, CAMK2A, CAMKK2, CARD8, CHSY1, CORO2A, CPEB3, DIP2C, DLGAP4, DNAJC16, DNAJC9, DZIP1, EFR3B, EXOC6B, FAIM2, FASTKD2, FNBP4, INPP5F, LRCH1, NLGN4Y, NLRP1, NRXN2, PADI2, PCNX, PDS5B, PLEKHA6, PSD3, R3HDM2, RPH3A, SBNO2, SEZ6L, STK38L, TBC1D30, THOC5, TLL2, USP20, ZBTB1, ZFP30
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| Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
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| Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, Tanaka A,Kotani H, Nomura N, Ohara O.
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| DNA Res 6(1):63-70. 1999
|