Citations for
1ASCL1, VSX2
VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures.
Wright LS, Pinilla I, Saha J, Clermont JM, Lien JS, Borys KD, Capowski EE, Phillips MJ, Gamm DM.
PLoS One 10(8):e0135830. doi: 10.1371/journal.pone.0135830. eCollection 2015. 2015
2ASCL1, HELT
Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation.
Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y.
Dev Biol. Feb 15;398(2):280-91. doi: 10.1016/j.ydbio.2014.12.003. Epub 2014 Dec 12 2015
3ASCL1, HELT
Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.
Wende CZ, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, Wurst W, Guimera J.
PLoS One. May 20;10(5):e0127681. doi: 10.1371/journal.pone.0127681. eCollection 2015 2015
4ASCL1, PTF1A
Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina.
Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M.
PLoS One 9(3):e92113. doi: 10.1371/journal.pone.0092113. eCollection 2014. 2014
5ASCL1, FOXO3
FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.
Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A.
Cell Rep 4(3):477-91. doi: 10.1016/j.celrep.2013.06.035. Epub 2013 Jul 25. 2013
6ASCL1, DMRT3, DMRTA1, NEUROG2
Dmrta1 regulates proneural gene expression downstream of Pax6 in the mammalian telencephalon.
Kikkawa T, Obayashi T, Takahashi M, Fukuzaki-Dohi U, Numayama-Tsuruta K, Osumi N.
Genes Cells 18(8):636-49. doi: 10.1111/gtc.12061. Epub 2013 May 16. 2013
7ASCL1, NEUROG3
Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus.
Pelling M, Anthwal N, McNay D, Gradwohl G, Leiter AB, Guillemot F, Ang SL.
Dev Biol 349(2):406-16. Epub 2010 Nov 11. 2011
8ASCL1
Ascl1 lineage cells contribute to ischemia-induced neurogenesis and oligodendrogenesis.
Zhang RL, Chopp M, Roberts C, Jia L, Wei M, Lu M, Wang X, Pourabdollah S, Zhang ZG.
J Cereb Blood Flow Metab 31(2):614-25. Epub 2010 Aug 25. 2011
9ASCL1, DBH, HAND2, PHOX2B, TCF3
Interaction of Hand2 and E2a is important for transcription of Phox2b in sympathetic nervous system neuron differentiation.
Hashimoto Y, Tsutsumi M, Myojin R, Maruta K, Onoda F, Tashiro F, Ohtsu M, Murakami Y.
Biochem Biophys Res Commun 408(1):38-44. Epub 2011 Mar 29. 2011
10ASCL1
Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina.
Brzezinski JA 4th, Kim EJ, Johnson JE, Reh TA.
Development 138(16):3519-31. Epub 2011 Jul 19. 2011
11ASCL1
Ascl1 genetics reveals insights into cerebellum local circuit assembly.
Sudarov A, Turnbull RK, Kim EJ, Lebel-Potter M, Guillemot F, Joyner AL.
J Neurosci 31(30):11055-69. 2011
12ASCL1, LMO3, NHLH2
Oncogenic LMO3 collaborates with HEN2 to enhance neuroblastoma cell growth through transactivation of Mash1.
Isogai E, Ohira M, Ozaki T, Oba S, Nakamura Y, Nakagawara A.
PLoS One 6(5):e19297. doi: 10.1371/journal.pone.0019297. 2011
13ASCL1, MYT1L, POU3F2
Direct conversion of fibroblasts to functional neurons by defined factors.
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M.
Nature 463(7284):1035-41. Epub 2010 Jan 27. 2010
14ASCL1
Examination of the MASH1 gene in patients with Parkinson's disease.
Deng H, Yang H, Le W, Deng X, Xu H, Xiong W, Zhu S, Xie W, Song Z, Jankovic J.
Biochem Biophys Res Commun 392(4):548-50. Epub 2010 Jan 25.PMID: 20097173 2010
15ASCL1
Efficient discovery of ASCL1 regulatory sequences through transgene pooling.
McGaughey DM, McCallion AS.
Genomics 95(6):363-9. Epub 2010 Mar 4.PMID: 20206680 2010
16ASCL1, NEUROG2
Neurog2 controls the leading edge of neurogenesis in the mammalian retina.
Hufnagel RB, Le TT, Riesenberg AL, Brown NL.
Dev Biol 340(2):490-503. Epub 2010 Feb 6. 2010
17ASCL1, CBFA2T2, CBFA2T3, NEUROG2, RUNX1T1
Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.
Aaker JD, Patineau AL, Yang HJ, Ewart DT, Nakagawa Y, McLoon SC, Koyano-Nakagawa N.
Neurosci Lett 474(1):46-51. Epub 2010 Mar 7. 2010
18ASCL1, GADD45G
Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation.
Huang HS, Kubish GM, Redmond TM, Turner DL, Thompson RC, Murphy GG, Uhler MD.
Mol Cell Neurosci 44(3):282-96. doi: 10.1016/j.mcn.2010.03.014. Epub 2010 Apr 9. 2010
19ASCL1
Regionally specified human neural progenitor cells derived from the mesencephalon and forebrain undergo increased neurogenesis following overexpression of ASCL1.
Kim HJ, McMillan E, Han F, Svendsen CN.
Stem Cells 27(2):390-8.PMID: 19008346 2009
20ASCL1
Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein.
Fähling M, Mrowka R, Steege A, Kirschner KM, Benko E, Förstera B, Persson PB, Thiele BJ, Meier JC, Scholz H.
J Biol Chem 284(7):4255-66. Epub 2008 Dec 19.PMID: 19097999 2009
21ASCL1, DLL3, NEUROG2
Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube.
Henke RM, Meredith DM, Borromeo MD, Savage TK, Johnson JE.
Dev Biol 328(2):529-40. Epub 2009 Jan 14. 2009
22ASCL1
Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architecture.
Kim EJ, Battiste J, Nakagawa Y, Johnson JE.
Mol Cell Neurosci 38(4):595-606. Epub 2008 May 20.PMID: 18585058 2008
23ASCL1
Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1.
Gamm DM, Wright LS, Capowski EE, Shearer RL, Meyer JS, Kim HJ, Schneider BL, Melvan JN, Svendsen CN.
Stem Cells 26(12):3182-93. Epub 2008 Sep 18.PMID: 18802035 2008
24ASCL1, ASH1L
Achaete-scute homolog-1 linked to remodeling and preneoplasia of pulmonary epithelium.
Wang XY, Dakir el H, Naizhen X, Jensen-Taubman SM, DeMayo FJ, Linnoila RI.
Lab Invest 87(6):527-39.PMID: 17507989 2007
25NEUROD1, NEUROG1, NEUROG2, ASCL1
Coupling of cell migration with neurogenesis by proneural bHLH factors.
Ge W, He F, Kim KJ, Blanchi B, Coskun V, Nguyen L, Wu X, Zhao J, Heng JI, Martinowich K, Tao J, Wu H, Castro D, Sobeih MM, Corfas G, Gleeson JG, Greenberg ME, Guillemot F, Sun YE.
Proc Natl Acad Sci U S A 103(5):1319-24. Epub 2006 Jan 23. 2006
26ASCL1
Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells.
McNay DE, Pelling M, Claxton S, Guillemot F, Ang SL.
Mol Endocrinol 20(7):1623-32. Epub 2006 Feb 9. 2006
27PHOX2B, ASCL1
Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.
Ide M, Yamada K, Toyota T, Iwayama Y, Ishitsuka Y, Minabe Y, Nakamura K, Hattori N, Asada T, Mizuno Y, Mori N, Yoshikawa T.
Hum Genet 117(6):520-7. Epub 2005 Jul 14. 2005
28ASCL1
Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma.
Somasundaram K, Reddy SP, Vinnakota K, Britto R, Subbarayan M, Nambiar S, Hebbar A, Samuel C, Shetty M, Sreepathi HK, Santosh V, Hegde AS, Hegde S, Kondaiah P, Rao MR.
Oncogene 24(47):7073-83. 2005
29ASCL1, NEUROD4
Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors.
Ohsawa R, Ohtsuka T, Kageyama R.
J Neurosci 25(25):5857-65. 2005
30HES1, UBQLN1, ASCL1
Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells.
Persson P, Stockhausen MT, Pahlman S, Axelson H.
Int J Oncol 25(5):1213-21. 2004
31ASCL1, CCHS4
Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse).
de Pontual L, Nepote V, Attie-Bitach T, Al Halabiah H, Trang H, Elghouzzi V, Levacher B, Benihoud K, Auge J, Faure C, Laudier B, Vekemans M, Munnich A, Perricaudet M, Guillemot F, Gaultier C, Lyonnet S, Simonneau M, Amiel J.
Hum Mol Genet 12(23):3173-80. Epub 2003 Oct 07. 2003
32ASCL1, PCSK6
Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1.
Yoshida I, Koide S, Hasegawa SI, Nakagawara A, Tsuji A, Matsuda Y.
Biochem J 360(Pt 3):683-9. 2001
33ASCL1, ASH1L
huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.
Nakamura T, Blechman J, Tada S, Rozovskaia T, Itoyama T, Bullrich F, Mazo A, Croce CM, Geiger B, Canaani E.
Proc Natl Acad Sci U S A 97(13):7284-9. 2000
34ASCL1
Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells.
Soderholm H, et al.
Biochem Biophys Res Commun 256(3):557-63. 1999
35ASCL1, HSP90B1
Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23.
Renault B, et al.
Genomics 30 : 81-83. 1995
36NOS1, ATXN2, ASCL1
Exclusion of the neuronal nitric oxide synthase gene and the human achaete-scute homologue I gene as candidate loci for spinal cerebellar ataxia 2.
Twells R, et al.
Am J Hum Genet 56 : 336-337. 1995
37ASCL1, ASCL2
Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors.
Ball DW, et al.
Proc Natl Acad Sci U S A 90 : 5648-5652. 1993