| 1 | ASCL1, VSX2
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| VSX2 and ASCL1 Are Indicators of Neurogenic Competence in Human Retinal Progenitor Cultures.
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| Wright LS, Pinilla I, Saha J, Clermont JM, Lien JS, Borys KD, Capowski EE, Phillips MJ, Gamm DM.
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| PLoS One 10(8):e0135830. doi: 10.1371/journal.pone.0135830. eCollection 2015.
2015
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| 2 | ASCL1, HELT
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| Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation.
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| Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y.
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| Dev Biol. Feb 15;398(2):280-91. doi: 10.1016/j.ydbio.2014.12.003. Epub 2014 Dec 12 2015
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| 3 | ASCL1, HELT
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| Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.
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| Wende CZ, Zoubaa S, Blak A, Echevarria D, Martinez S, Guillemot F, Wurst W, Guimera J.
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| PLoS One. May 20;10(5):e0127681. doi: 10.1371/journal.pone.0127681. eCollection 2015 2015
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| 4 | ASCL1, PTF1A
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| Ascl1 as a novel player in the Ptf1a transcriptional network for GABAergic cell specification in the retina.
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| Mazurier N, Parain K, Parlier D, Pretto S, Hamdache J, Vernier P, Locker M, Bellefroid E, Perron M.
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| PLoS One 9(3):e92113. doi: 10.1371/journal.pone.0092113. eCollection 2014.
2014
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| 5 | ASCL1, FOXO3
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| FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis.
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| Webb AE, Pollina EA, Vierbuchen T, Urbán N, Ucar D, Leeman DS, Martynoga B, Sewak M, Rando TA, Guillemot F, Wernig M, Brunet A.
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| Cell Rep 4(3):477-91. doi: 10.1016/j.celrep.2013.06.035. Epub 2013 Jul 25.
2013
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| 6 | ASCL1, DMRT3, DMRTA1, NEUROG2
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| Dmrta1 regulates proneural gene expression downstream of Pax6 in the mammalian telencephalon.
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| Kikkawa T, Obayashi T, Takahashi M, Fukuzaki-Dohi U, Numayama-Tsuruta K, Osumi N.
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| Genes Cells 18(8):636-49. doi: 10.1111/gtc.12061. Epub 2013 May 16. 2013
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| 7 | ASCL1, NEUROG3
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| Differential requirements for neurogenin 3 in the development of POMC and NPY neurons in the hypothalamus.
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| Pelling M, Anthwal N, McNay D, Gradwohl G, Leiter AB, Guillemot F, Ang SL.
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| Dev Biol 349(2):406-16. Epub 2010 Nov 11.
2011
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| 8 | ASCL1
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| Ascl1 lineage cells contribute to ischemia-induced neurogenesis and oligodendrogenesis.
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| Zhang RL, Chopp M, Roberts C, Jia L, Wei M, Lu M, Wang X, Pourabdollah S, Zhang ZG.
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| J Cereb Blood Flow Metab 31(2):614-25. Epub 2010 Aug 25.
2011
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| 9 | ASCL1, DBH, HAND2, PHOX2B, TCF3
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| Interaction of Hand2 and E2a is important for transcription of Phox2b in sympathetic nervous system neuron differentiation.
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| Hashimoto Y, Tsutsumi M, Myojin R, Maruta K, Onoda F, Tashiro F, Ohtsu M, Murakami Y.
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| Biochem Biophys Res Commun 408(1):38-44. Epub 2011 Mar 29.
2011
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| 10 | ASCL1
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| Ascl1 expression defines a subpopulation of lineage-restricted progenitors in the mammalian retina.
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| Brzezinski JA 4th, Kim EJ, Johnson JE, Reh TA.
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| Development 138(16):3519-31. Epub 2011 Jul 19.
2011
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| 11 | ASCL1
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| Ascl1 genetics reveals insights into cerebellum local circuit assembly.
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| Sudarov A, Turnbull RK, Kim EJ, Lebel-Potter M, Guillemot F, Joyner AL.
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| J Neurosci 31(30):11055-69.
2011
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| 12 | ASCL1, LMO3, NHLH2
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| Oncogenic LMO3 collaborates with HEN2 to enhance neuroblastoma cell growth through transactivation of Mash1.
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| Isogai E, Ohira M, Ozaki T, Oba S, Nakamura Y, Nakagawara A.
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| PLoS One 6(5):e19297. doi: 10.1371/journal.pone.0019297.
2011
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| 13 | ASCL1, MYT1L, POU3F2
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| Direct conversion of fibroblasts to functional neurons by defined factors.
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| Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Südhof TC, Wernig M.
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| Nature 463(7284):1035-41. Epub 2010 Jan 27.
2010
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| 14 | ASCL1
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| Examination of the MASH1 gene in patients with Parkinson's disease.
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| Deng H, Yang H, Le W, Deng X, Xu H, Xiong W, Zhu S, Xie W, Song Z, Jankovic J.
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| Biochem Biophys Res Commun 392(4):548-50. Epub 2010 Jan 25.PMID: 20097173 2010
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| 15 | ASCL1
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| Efficient discovery of ASCL1 regulatory sequences through transgene pooling.
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| McGaughey DM, McCallion AS.
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| Genomics 95(6):363-9. Epub 2010 Mar 4.PMID: 20206680 2010
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| 16 | ASCL1, NEUROG2
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| Neurog2 controls the leading edge of neurogenesis in the mammalian retina.
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| Hufnagel RB, Le TT, Riesenberg AL, Brown NL.
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| Dev Biol 340(2):490-503. Epub 2010 Feb 6.
2010
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| 17 | ASCL1, CBFA2T2, CBFA2T3, NEUROG2, RUNX1T1
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| Interaction of MTG family proteins with NEUROG2 and ASCL1 in the developing nervous system.
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| Aaker JD, Patineau AL, Yang HJ, Ewart DT, Nakagawa Y, McLoon SC, Koyano-Nakagawa N.
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| Neurosci Lett 474(1):46-51. Epub 2010 Mar 7.
2010
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| 18 | ASCL1, GADD45G
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| Direct transcriptional induction of Gadd45gamma by Ascl1 during neuronal differentiation.
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| Huang HS, Kubish GM, Redmond TM, Turner DL, Thompson RC, Murphy GG, Uhler MD.
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| Mol Cell Neurosci 44(3):282-96. doi: 10.1016/j.mcn.2010.03.014. Epub 2010 Apr 9.
2010
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| 19 | ASCL1
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| Regionally specified human neural progenitor cells derived from the mesencephalon and forebrain undergo increased neurogenesis following overexpression of ASCL1.
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| Kim HJ, McMillan E, Han F, Svendsen CN.
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| Stem Cells 27(2):390-8.PMID: 19008346 2009
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| 20 | ASCL1
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| Translational regulation of the human achaete-scute homologue-1 by fragile X mental retardation protein.
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| Fähling M, Mrowka R, Steege A, Kirschner KM, Benko E, Förstera B, Persson PB, Thiele BJ, Meier JC, Scholz H.
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| J Biol Chem 284(7):4255-66. Epub 2008 Dec 19.PMID: 19097999 2009
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| 21 | ASCL1, DLL3, NEUROG2
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| Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube.
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| Henke RM, Meredith DM, Borromeo MD, Savage TK, Johnson JE.
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| Dev Biol 328(2):529-40. Epub 2009 Jan 14. 2009
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| 22 | ASCL1
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| Ascl1 (Mash1) lineage cells contribute to discrete cell populations in CNS architecture.
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| Kim EJ, Battiste J, Nakagawa Y, Johnson JE.
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| Mol Cell Neurosci 38(4):595-606. Epub 2008 May 20.PMID: 18585058 2008
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| 23 | ASCL1
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| Regulation of prenatal human retinal neurosphere growth and cell fate potential by retinal pigment epithelium and Mash1.
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| Gamm DM, Wright LS, Capowski EE, Shearer RL, Meyer JS, Kim HJ, Schneider BL, Melvan JN, Svendsen CN.
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| Stem Cells 26(12):3182-93. Epub 2008 Sep 18.PMID: 18802035 2008
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| 24 | ASCL1, ASH1L
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| Achaete-scute homolog-1 linked to remodeling and preneoplasia of pulmonary epithelium.
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| Wang XY, Dakir el H, Naizhen X, Jensen-Taubman SM, DeMayo FJ, Linnoila RI.
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| Lab Invest 87(6):527-39.PMID: 17507989 2007
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| 25 | NEUROD1, NEUROG1, NEUROG2, ASCL1
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| Coupling of cell migration with neurogenesis by proneural bHLH factors.
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| Ge W, He F, Kim KJ, Blanchi B, Coskun V, Nguyen L, Wu X, Zhao J, Heng JI, Martinowich K, Tao J, Wu H, Castro D, Sobeih MM, Corfas G, Gleeson JG, Greenberg ME, Guillemot F, Sun YE.
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| Proc Natl Acad Sci U S A 103(5):1319-24. Epub 2006 Jan 23. 2006
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| 26 | ASCL1
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| Mash1 is required for generic and subtype differentiation of hypothalamic neuroendocrine cells.
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| McNay DE, Pelling M, Claxton S, Guillemot F, Ang SL.
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| Mol Endocrinol 20(7):1623-32. Epub 2006 Feb 9. 2006
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| 27 | PHOX2B, ASCL1
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| Genetic association analyses of PHOX2B and ASCL1 in neuropsychiatric disorders: evidence for association of ASCL1 with Parkinson's disease.
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| Ide M, Yamada K, Toyota T, Iwayama Y, Ishitsuka Y, Minabe Y, Nakamura K, Hattori N, Asada T, Mizuno Y, Mori N, Yoshikawa T.
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| Hum Genet 117(6):520-7. Epub 2005 Jul 14. 2005
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| 28 | ASCL1
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| Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma.
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| Somasundaram K, Reddy SP, Vinnakota K, Britto R, Subbarayan M, Nambiar S, Hebbar A, Samuel C, Shetty M, Sreepathi HK, Santosh V, Hegde AS, Hegde S, Kondaiah P, Rao MR.
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| Oncogene 24(47):7073-83. 2005
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| 29 | ASCL1, NEUROD4
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| Mash1 and Math3 are required for development of branchiomotor neurons and maintenance of neural progenitors.
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| Ohsawa R, Ohtsuka T, Kageyama R.
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| J Neurosci 25(25):5857-65. 2005
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| 30 | HES1, UBQLN1, ASCL1
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| Ubiquilin-1 is a novel HASH-1-complexing protein that regulates levels of neuronal bHLH transcription factors in human neuroblastoma cells.
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| Persson P, Stockhausen MT, Pahlman S, Axelson H.
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| Int J Oncol 25(5):1213-21. 2004
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| 31 | ASCL1, CCHS4
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| Noradrenergic neuronal development is impaired by mutation of the proneural HASH-1 gene in congenital central hypoventilation syndrome (Ondine's curse).
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| de Pontual L, Nepote V, Attie-Bitach T, Al Halabiah H, Trang H, Elghouzzi V, Levacher B, Benihoud K, Auge J, Faure C, Laudier B, Vekemans M, Munnich A, Perricaudet M, Guillemot F, Gaultier C, Lyonnet S, Simonneau M, Amiel J.
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| Hum Mol Genet 12(23):3173-80. Epub 2003 Oct 07. 2003
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| 32 | ASCL1, PCSK6
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| Proprotein convertase PACE4 is down-regulated by the basic helix-loop-helix transcription factor hASH-1 and MASH-1.
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| Yoshida I, Koide S, Hasegawa SI, Nakagawara A, Tsuji A, Matsuda Y.
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| Biochem J 360(Pt 3):683-9. 2001
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| 33 | ASCL1, ASH1L
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| huASH1 protein, a putative transcription factor encoded by a human homologue of the Drosophila ash1 gene, localizes to both nuclei and cell-cell tight junctions.
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| Nakamura T, Blechman J, Tada S, Rozovskaia T, Itoyama T, Bullrich F, Mazo A, Croce CM, Geiger B, Canaani E.
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| Proc Natl Acad Sci U S A 97(13):7284-9. 2000
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| 34 | ASCL1
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| Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells.
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| Soderholm H, et al.
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| Biochem Biophys Res Commun 256(3):557-63. 1999
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| 35 | ASCL1, HSP90B1
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| Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23.
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| Renault B, et al.
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| Genomics 30 : 81-83. 1995
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| 36 | NOS1, ATXN2, ASCL1
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| Exclusion of the neuronal nitric oxide synthase gene and the human achaete-scute homologue I gene as candidate loci for spinal cerebellar ataxia 2.
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| Twells R, et al.
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| Am J Hum Genet 56 : 336-337. 1995
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| 37 | ASCL1, ASCL2
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| Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors.
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| Ball DW, et al.
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| Proc Natl Acad Sci U S A 90 : 5648-5652. 1993
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