1 | ASAP1, MYH9
|
| The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network.
|
| Chen PW, Jian X, Heissler SM, Le K, Luo R, Jenkins LM, Nagy A, Moss J, Sellers JR, Randazzo PA.
|
| J Biol Chem 291(14):7517-26. doi: 10.1074/jbc.M115.701292. Epub 2016 Feb 17.
2016
|
2 | ASAP1, RAB11A, RAB11FIP3, RAB3IP
|
| The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.
|
| Wang J, Deretic D.
|
| J Cell Sci 128(7):1375-85. doi: 10.1242/jcs.162925. Epub 2015 Feb 11.
2015
|
3 | ASAP1
|
| A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.
|
| Kahn RA, Lambright DG.
|
| Structure 23(11):1971-3. doi: 10.1016/j.str.2015.10.002.
2015
|
4 | ASAP1
|
| Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
|
| Jian X, Tang WK, Zhai P, Roy NS, Luo R, Gruschus JM, Yohe ME, Chen PW, Li Y, Byrd RA, Xia D, Randazzo PA.
|
| Structure 23(11):1977-88. doi: 10.1016/j.str.2015.08.008. Epub 2015 Sep 10.
2015
|
5 | ASAP1
|
| Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
|
| Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nürnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, Nejentsev S.
|
| Nat Genet 47(5):523-527. doi: 10.1038/ng.3248. Epub 2015 Mar 16.
2015
|
6 | ASAP1, KDELR1, kDELR2
|
| A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.
|
| Ruggiero C, Fragassi G, Grossi M, Picciani B, Di Martino R, Capitani M, Buccione R, Luini A, Sallese M.
|
| Oncotarget 6(5):3375-93.
2015
|
7 | ASAP1, IKBKB
|
| AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.
|
| Tien DN, Kishihata M, Yoshikawa A, Hashimoto A, Sabe H, Nishi E, Kamei K, Arai H, Kita T, Kimura T, Yokode M, Ashida N.
|
| Sci Rep 4:5094. doi: 10.1038/srep05094.
2014
|
8 | ASAP1
|
| Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer.
|
| Hou T, Yang C, Tong C, Zhang H, Xiao J, Li J.
|
| Int J Clin Exp Pathol 7(1):280-7. eCollection 2014.
2013
|
9 | ASAP1, PRKD2, RAB5C
|
| Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.
|
| Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H.
|
| J Cell Biol 197(7):983-96. doi: 10.1083/jcb.201201065.
2012
|
10 | ARF4, ASAP1, RAB11A, RAB3IP, RAB8A
|
| The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.
|
| Wang J, Morita Y, Mazelova J, Deretic D.
|
| EMBO J 31(20):4057-71. doi: 10.1038/emboj.2012.253. Epub 2012 Sep 14.
2012
|
11 | ARHGEF2, ASAP1
|
| GEFH1 binds ASAP1 and regulates podosome formation.
|
| Shiba Y, Randazzo PA.
|
| Biochem Biophys Res Commun 406(4):574-9. Epub 2011 Feb 23.
2011
|
12 | ARF6, ASAP1, IQSEC1
|
| GEP100-Arf6-AMAP1-cortactin pathway frequently used in cancer invasion is activated by VEGFR2 to promote angiogenesis.
|
| Hashimoto A, Hashimoto S, Ando R, Noda K, Ogawa E, Kotani H, Hirose M, Menju T, Morishige M, Manabe T, Toda Y, Ishida S, Sabe H.
|
| PLoS One 6(8):e23359. doi: 10.1371/journal.pone.0023359. Epub 2011 Aug 15.
2011
|
13 | ASAP1
|
| ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
|
| Müller T, Stein U, Poletti A, Garzia L, Rothley M, Plaumann D, Thiele W, Bauer M, Galasso A, Schlag P, Pankratz M, Zollo M, Sleeman JP.
|
| Oncogene 29(16):2393-403. Epub 2010 Feb 15.
2010
|
14 | ARF6, ASAP1, ASAP2, ASAP3
|
| The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism.
|
| Ismail SA, Vetter IR, Sot B, Wittinghofer A.
|
| Cell 141(5):812-21 2010
|
15 | ASAP1, RHO
|
| Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4.
|
| Mazelova J, Astuto-Gribble L, Inoue H, Tam BM, Schonteich E, Prekeris R, Moritz OL, Randazzo PA, Deretic D.
|
| EMBO J 28(3):183-92. Epub 2009 Jan 15.
2009
|
16 | ARF6, ASAP1, IQSEC1
|
| The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.
|
| Sabe H, Hashimoto S, Morishige M, Ogawa E, Hashimoto A, Nam JM, Miura K, Yano H, Onodera Y.
|
| Traffic 10(8):982-93. doi: 10.1111/j.1600-0854.2009.00917.x. Epub 2009 Apr 21. Review.
2009
|
17 | ASAP1, IKBKG
|
| Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.
|
| Inoue H, Ha VL, Prekeris R, Randazzo PA.
|
| Mol Biol Cell 19(10):4224-37. Epub 2008 Aug 6.
2008
|
18 | ASAP1
|
| ASAP1, a gene at 8q24, is associated with prostate cancer metastasis.
|
| Lin D, Watahiki A, Bayani J, Zhang F, Liu L, Ling V, Sadar MD, English J, Fazli L, So A, Gout PW, Gleave M, Squire JA, Wang YZ.
|
| Cancer Res 68(11):4352-9.
2008
|
19 | ASAP1, ASAP2
|
| Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.
|
| Matsui C, Kaieda S, Ikegami T, Mimori-Kiyosue Y.
|
| J Biol Chem 283(47):33006-20. Epub 2008 Sep 11.
2008
|
20 | ASAP1, ASAP2, SH3KBP1
|
| CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.
|
| Nam JM, Onodera Y, Mazaki Y, Miyoshi H, Hashimoto S, Sabe H.
|
| EMBO J 26(3):647-56. Epub 2007 Jan 25. 2007
|
21 | ASAP1
|
| Src-dependent phosphorylation of ASAP1 regulates podosomes.
|
| Bharti S, Inoue H, Bharti K, Hirsch DS, Nie Z, Yoon HY, Artym V, Yamada KM, Mueller SC, Barr VA, Randazzo PA.
|
| Mol Cell Biol 27(23):8271-83. Epub 2007 Sep 24.PMID: 17893324 2007
|
22 | ARF6, ASAP1
|
| Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
|
| Hashimoto S, Hirose M, Hashimoto A, Morishige M, Yamada A, Hosaka H, Akagi K, Ogawa E, Oneyama C, Agatsuma T, Okada M, Kobayashi H, Wada H, Nakano H, Ikegami T, Nakagawa A, Sabe H.
|
| Proc Natl Acad Sci U S A 103(18):7036-41. Epub 2006 Apr 24. 2006
|
23 | ASAP1, DLGAP3, PTK2
|
| FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.
|
| Bongiorno-Borbone L, Kadare G, Benfenati F, Girault JA.
|
| Biochem Biophys Res Commun 337(2):641-6. Epub 2005 Sep 26. 2005
|
24 | ASAP1
|
| DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.
|
| Furman C, Short SM, Subramanian RR, Zetter BR, Roberts TM.
|
| J Biol Chem 277(10):7962-9. 2002
|
25 | ASAP1, REPS2
|
| Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.
|
| Oshiro T, Koyama S, Sugiyama S, Kondo A, Onodera Y, Asahara T, Sabe H, Kikuchi A.
|
| J Biol Chem 277(41):38618-26. Epub 2002 Jul 30. 2002
|
26 | ACAP1, ACAP2, ARF6, ASAP1, ASAP2
|
| ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.
|
| Jackson TR, Brown FD, Nie Z, Miura K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA.
|
| J Cell Biol 151(3):627-38. 2000
|
27 | ASAP1, ASAP2, REG3A
|
| Identification of a new Pyk2 target protein with Arf-GAP activity.
|
| Andreev J, Simon JP, Sabatini DD, Kam J, Plowman G, Randazzo PA, Schlessinger J.
|
| Mol Cell Biol 19(3):2338-50. 1999
|
28 | AARS2, ADAMTSL3, AHRR, AMIGO1, ANKFY1, ARHGAP31, ARID1A, ARID1B, ASAP1, ASB1, BACE1, BIRC6, BRPF3, C14orf118, CASKIN2, CCPG1, CD2BP2, CNOT6, COG6, CPAMD8, DCDC2, DLG3, ERBIN, ERGIC1, FAM190B, FAM63B, FBXO40, FILIP1, FSTL5, FZR1, GALNTL1, GATAD2B, GDA, GMEB2, GNPTAB, GRID1, GRIPAP1, HECTD1, HEG1, HHATL, INTU, IPO9, ISY1, KCNH3, KIAA1143, KIAA1191, KIAA1217, KIAA1274, LCHN, LMBR1L, LRFN2, LRRC47, MACF1, MAP7D1, MIER2, MTA3, MYO5B, MYOF, MYORG, NDFIP2, NDRG2, NELFB, NLGN4X, NLN, OGDHL, PAIP2B, PAK7, PECR, PLEKHG1, PLEKHH1, PNKD, PNMAL2, PPP1R9A, PRDM10, REXO1, RIMKLB, RNF150, SGPL1, SHROOM4, SLC39A10, SLC45A4, SRGAP2, STK36, SULF2, TBC1D24, TLE4, TMCC3, TPCN1, TRMT6, TTC7A, TTC7B, USP31, ZBTB21, ZBTB47, ZC4H2, ZNF490, ZNF644, ZNF777
|
| Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.
|
| Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O.
|
| DNA Res 6(5):329-36. 1999
|
29 | ASAP1, ASAP2, BIRC6, ERBIN, INTS2, KIAA1239, KIAA1244, KIAA1257, KIAA1370, KIAA1462, KIAA1467, KIAA1539, KIAA1949, KIFBP, MED23, MTUS1, PLEKHG1, PLEKHH1, RNF150, SERINC2, UVSSA, VANGL2, WWC3, XPO5, XPO7, ZDHHC8, ZMIZ1, ZNF512B
|
| Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
|
| Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O.
|
| DNA Res 6(5):337-45. 1999
|