Citations for
1ASAP1, MYH9
The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network.
Chen PW, Jian X, Heissler SM, Le K, Luo R, Jenkins LM, Nagy A, Moss J, Sellers JR, Randazzo PA.
J Biol Chem 291(14):7517-26. doi: 10.1074/jbc.M115.701292. Epub 2016 Feb 17. 2016
2ASAP1, RAB11A, RAB11FIP3, RAB3IP
The Arf and Rab11 effector FIP3 acts synergistically with ASAP1 to direct Rabin8 in ciliary receptor targeting.
Wang J, Deretic D.
J Cell Sci 128(7):1375-85. doi: 10.1242/jcs.162925. Epub 2015 Feb 11. 2015
3ASAP1
A PH Domain with Dual Phospholipid Binding Sites Regulates the ARF GAP, ASAP1.
Kahn RA, Lambright DG.
Structure 23(11):1971-3. doi: 10.1016/j.str.2015.10.002. 2015
4ASAP1
Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1.
Jian X, Tang WK, Zhai P, Roy NS, Luo R, Gruschus JM, Yohe ME, Chen PW, Li Y, Byrd RA, Xia D, Randazzo PA.
Structure 23(11):1977-88. doi: 10.1016/j.str.2015.08.008. Epub 2015 Sep 10. 2015
5ASAP1
Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration.
Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, Thye T, Meyer CG, Nürnberg P, Horstmann RD, Drobniewski F, Plagnol V, Barrett JC, Nejentsev S.
Nat Genet 47(5):523-527. doi: 10.1038/ng.3248. Epub 2015 Mar 16. 2015
6ASAP1, KDELR1, kDELR2
A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation.
Ruggiero C, Fragassi G, Grossi M, Picciani B, Di Martino R, Capitani M, Buccione R, Luini A, Sallese M.
Oncotarget 6(5):3375-93. 2015
7ASAP1, IKBKB
AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.
Tien DN, Kishihata M, Yoshikawa A, Hashimoto A, Sabe H, Nishi E, Kamei K, Arai H, Kita T, Kimura T, Yokode M, Ashida N.
Sci Rep 4:5094. doi: 10.1038/srep05094. 2014
8ASAP1
Overexpression of ASAP1 is associated with poor prognosis in epithelial ovarian cancer.
Hou T, Yang C, Tong C, Zhang H, Xiao J, Li J.
Int J Clin Exp Pathol 7(1):280-7. eCollection 2014. 2013
9ASAP1, PRKD2, RAB5C
Rab5c promotes AMAP1-PRKD2 complex formation to enhance β1 integrin recycling in EGF-induced cancer invasion.
Onodera Y, Nam JM, Hashimoto A, Norman JC, Shirato H, Hashimoto S, Sabe H.
J Cell Biol 197(7):983-96. doi: 10.1083/jcb.201201065. 2012
10ARF4, ASAP1, RAB11A, RAB3IP, RAB8A
The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.
Wang J, Morita Y, Mazelova J, Deretic D.
EMBO J 31(20):4057-71. doi: 10.1038/emboj.2012.253. Epub 2012 Sep 14. 2012
11ARHGEF2, ASAP1
GEFH1 binds ASAP1 and regulates podosome formation.
Shiba Y, Randazzo PA.
Biochem Biophys Res Commun 406(4):574-9. Epub 2011 Feb 23. 2011
12ARF6, ASAP1, IQSEC1
GEP100-Arf6-AMAP1-cortactin pathway frequently used in cancer invasion is activated by VEGFR2 to promote angiogenesis.
Hashimoto A, Hashimoto S, Ando R, Noda K, Ogawa E, Kotani H, Hirose M, Menju T, Morishige M, Manabe T, Toda Y, Ishida S, Sabe H.
PLoS One 6(8):e23359. doi: 10.1371/journal.pone.0023359. Epub 2011 Aug 15. 2011
13ASAP1
ASAP1 promotes tumor cell motility and invasiveness, stimulates metastasis formation in vivo, and correlates with poor survival in colorectal cancer patients.
Müller T, Stein U, Poletti A, Garzia L, Rothley M, Plaumann D, Thiele W, Bauer M, Galasso A, Schlag P, Pankratz M, Zollo M, Sleeman JP.
Oncogene 29(16):2393-403. Epub 2010 Feb 15. 2010
14ARF6, ASAP1, ASAP2, ASAP3
The structure of an Arf-ArfGAP complex reveals a Ca2+ regulatory mechanism.
Ismail SA, Vetter IR, Sot B, Wittinghofer A.
Cell 141(5):812-21 2010
15ASAP1, RHO
Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4.
Mazelova J, Astuto-Gribble L, Inoue H, Tam BM, Schonteich E, Prekeris R, Moritz OL, Randazzo PA, Deretic D.
EMBO J 28(3):183-92. Epub 2009 Jan 15. 2009
16ARF6, ASAP1, IQSEC1
The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast cancer invasion and metastasis.
Sabe H, Hashimoto S, Morishige M, Ogawa E, Hashimoto A, Nam JM, Miura K, Yano H, Onodera Y.
Traffic 10(8):982-93. doi: 10.1111/j.1600-0854.2009.00917.x. Epub 2009 Apr 21. Review. 2009
17ASAP1, IKBKG
Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome.
Inoue H, Ha VL, Prekeris R, Randazzo PA.
Mol Biol Cell 19(10):4224-37. Epub 2008 Aug 6. 2008
18ASAP1
ASAP1, a gene at 8q24, is associated with prostate cancer metastasis.
Lin D, Watahiki A, Bayani J, Zhang F, Liu L, Ling V, Sadar MD, English J, Fazli L, So A, Gout PW, Gleave M, Squire JA, Wang YZ.
Cancer Res 68(11):4352-9. 2008
19ASAP1, ASAP2
Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF.
Matsui C, Kaieda S, Ikegami T, Mimori-Kiyosue Y.
J Biol Chem 283(47):33006-20. Epub 2008 Sep 11. 2008
20ASAP1, ASAP2, SH3KBP1
CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.
Nam JM, Onodera Y, Mazaki Y, Miyoshi H, Hashimoto S, Sabe H.
EMBO J 26(3):647-56. Epub 2007 Jan 25. 2007
21ASAP1
Src-dependent phosphorylation of ASAP1 regulates podosomes.
Bharti S, Inoue H, Bharti K, Hirsch DS, Nie Z, Yoon HY, Artym V, Yamada KM, Mueller SC, Barr VA, Randazzo PA.
Mol Cell Biol 27(23):8271-83. Epub 2007 Sep 24.PMID: 17893324 2007
22ARF6, ASAP1
Targeting AMAP1 and cortactin binding bearing an atypical src homology 3/proline interface for prevention of breast cancer invasion and metastasis.
Hashimoto S, Hirose M, Hashimoto A, Morishige M, Yamada A, Hosaka H, Akagi K, Ogawa E, Oneyama C, Agatsuma T, Okada M, Kobayashi H, Wada H, Nakano H, Ikegami T, Nakagawa A, Sabe H.
Proc Natl Acad Sci U S A 103(18):7036-41. Epub 2006 Apr 24. 2006
23ASAP1, DLGAP3, PTK2
FAK and PYK2 interact with SAP90/PSD-95-Associated Protein-3.
Bongiorno-Borbone L, Kadare G, Benfenati F, Girault JA.
Biochem Biophys Res Commun 337(2):641-6. Epub 2005 Sep 26. 2005
24ASAP1
DEF-1/ASAP1 is a GTPase-activating protein (GAP) for ARF1 that enhances cell motility through a GAP-dependent mechanism.
Furman C, Short SM, Subramanian RR, Zetter BR, Roberts TM.
J Biol Chem 277(10):7962-9. 2002
25ASAP1, REPS2
Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.
Oshiro T, Koyama S, Sugiyama S, Kondo A, Onodera Y, Asahara T, Sabe H, Kikuchi A.
J Biol Chem 277(41):38618-26. Epub 2002 Jul 30. 2002
26ACAP1, ACAP2, ARF6, ASAP1, ASAP2
ACAPs are arf6 GTPase-activating proteins that function in the cell periphery.
Jackson TR, Brown FD, Nie Z, Miura K, Foroni L, Sun J, Hsu VW, Donaldson JG, Randazzo PA.
J Cell Biol 151(3):627-38. 2000
27ASAP1, ASAP2, REG3A
Identification of a new Pyk2 target protein with Arf-GAP activity.
Andreev J, Simon JP, Sabatini DD, Kam J, Plowman G, Randazzo PA, Schlessinger J.
Mol Cell Biol 19(3):2338-50. 1999
28AARS2, ADAMTSL3, AHRR, AMIGO1, ANKFY1, ARHGAP31, ARID1A, ARID1B, ASAP1, ASB1, BACE1, BIRC6, BRPF3, C14orf118, CASKIN2, CCPG1, CD2BP2, CNOT6, COG6, CPAMD8, DCDC2, DLG3, ERBIN, ERGIC1, FAM190B, FAM63B, FBXO40, FILIP1, FSTL5, FZR1, GALNTL1, GATAD2B, GDA, GMEB2, GNPTAB, GRID1, GRIPAP1, HECTD1, HEG1, HHATL, INTU, IPO9, ISY1, KCNH3, KIAA1143, KIAA1161, KIAA1191, KIAA1217, KIAA1274, LCHN, LMBR1L, LRFN2, LRRC47, MACF1, MAP7D1, MIER2, MTA3, MYO5B, MYOF, NDFIP2, NDRG2, NELFB, NLGN4X, NLN, OGDHL, PAIP2B, PAK7, PECR, PLEKHG1, PLEKHH1, PNKD, PNMAL2, PPP1R9A, PRDM10, REXO1, RIMKLB, RNF150, SGPL1, SHROOM4, SLC39A10, SLC45A4, SRGAP2, STK36, SULF2, TBC1D24, TLE4, TMCC3, TPCN1, TRMT6, TTC7A, TTC7B, USP31, ZBTB47, ZC4H2, ZNF295, ZNF490, ZNF644, ZNF777
Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain.
Hirosawa M, Nagase T, Ishikawa K, Kikuno R, Nomura N, Ohara O.
DNA Res 6(5):329-36. 1999
29ASAP1, ASAP2, BIRC6, ERBIN, INTS2, KIAA1239, KIAA1244, KIAA1257, KIAA1370, KIAA1462, KIAA1467, KIAA1539, KIAA1949, KIF1BP, MED23, MTUS1, PLEKHG1, PLEKHH1, RNF150, SERINC2, UVSSA, VANGL2, WWC3, XPO5, XPO7, ZDHHC8, ZMIZ1, ZNF512B
Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T, Ishikawa K, Kikuno R, Hirosawa M, Nomura N, Ohara O.
DNA Res 6(5):337-45. 1999