| 1 | ARRB1, ARRB2, DRD4, KLHL12
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| Characterization of the interaction between the dopamine D4 receptor, KLHL12 and β-arrestins.
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| Skieterska K, Shen A, Clarisse D, Rondou P, Borroto-Escuela DO, Lintermans B, Fuxe K, Xiang YK, Van Craenenbroeck K.
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| Cell Signal 28(8):1001-14. doi: 10.1016/j.cellsig.2016.05.003. Epub 2016 May 5.
2016
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| 2 | ARRB2, USP20
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| Ubiquitin-specific Protease 20 Regulates the Reciprocal Functions of β-Arrestin2 in Toll-like Receptor 4-promoted Nuclear Factor κB (NFκB) Activation.
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| Jean-Charles PY, Zhang L, Wu JH, Han SO, Brian L, Freedman NJ, Shenoy SK.
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| J Biol Chem 291(14):7450-64. doi: 10.1074/jbc.M115.687129. Epub 2016 Feb 2.
2016
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| 3 | ARRB2, SSTR3
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| Recruitment of β-Arrestin into Neuronal Cilia Modulates Somatostatin Receptor Subtype 3 Ciliary Localization.
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| Green JA, Schmid CL, Bley E, Monsma PC, Brown A, Bohn LM, Mykytyn K.
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| Mol Cell Biol 36(1):223-35. doi: 10.1128/MCB.00765-15. Print 2016 Jan 1.
2015
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| 4 | ARR3, ARRB2
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| Defining the roles of arrestin2 and arrestin3 in vasoconstrictor receptor desensitization in hypertension.
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| Willets JM, Nash CA, Rainbow RD, Nelson CP, Challiss RA.
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| Am J Physiol Cell Physiol 309(3):C179-89. doi: 10.1152/ajpcell.00079.2015. Epub 2015 May 13.
2015
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| 5 | ARRB2
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| β-Arrestin2 plays a key role in the modulation of the pancreatic beta cell mass in mice.
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| Ravier MA, Leduc M, Richard J, Linck N, Varrault A, Pirot N, Roussel MM, Bockaert J, Dalle S, Bertrand G.
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| Diabetologia 57(3):532-41. doi: 10.1007/s00125-013-3130-7. Epub 2013 Dec 7.
2014
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| 6 | ARRB2
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| β-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10.
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| Li H, Hu D, Fan H, Zhang Y, LeSage GD, Caudle Y, Stuart C, Liu Z, Yin D.
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| J Biol Chem 289(33):23075-85. doi: 10.1074/jbc.M114.591495. Epub 2014 Jul 10.
2014
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| 7 | ARRB1, ARRB2
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| Deubiquitinases and their emerging roles in β-arrestin-mediated signaling.
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| Shenoy SK.
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| Methods Enzymol 535:351-70. doi: 10.1016/B978-0-12-397925-4.00020-1.
2014
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| 8 | ARRB2, HCAR1, NLRP3
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| Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity.
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| Hoque R, Farooq A, Ghani A, Gorelick F, Mehal WZ.
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| Gastroenterology 146(7):1763-74. doi: 10.1053/j.gastro.2014.03.014. Epub 2014 Mar 20.
2014
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| 9 | ARRB2, INPP5D, PVR, TIGIT
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| T-cell immunoglobulin and ITIM domain (TIGIT) receptor/poliovirus receptor (PVR) ligand engagement suppresses interferon-γ production of natural killer cells via β-arrestin 2-mediated negative signaling.
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| Li M, Xia P, Du Y, Liu S, Huang G, Chen J, Zhang H, Hou N, Cheng X, Zhou L, Li P, Yang X, Fan Z.
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| J Biol Chem 289(25):17647-57. doi: 10.1074/jbc.M114.572420.
2014
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| 10 | ARRB2, PDE4D, TRPV1
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| Phosphorylation regulates TRPV1 association with β-arrestin-2.
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| Por ED, Gomez R, Akopian AN, Jeske NA.
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| Biochem J 451(1):101-9. doi: 10.1042/BJ20121637.
2013
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| 11 | ARRB2
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| The influence of beta-arrestin2 on cannabinoid CB1 receptor coupling to G-proteins and subcellular localization and relative levels of beta-arrestin1 and 2 in mouse brain.
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| Breivogel CS, Puri V, Lambert JM, Hill DK, Huffman JW, Razdan RK.
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| J Recept Signal Transduct Res 33(6):367-79. doi: 10.3109/10799893.2013.838787. Epub 2013 Oct 4.
2013
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| 12 | ARRB2, FFAR2
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| β-Arrestin 2 mediates G protein-coupled receptor 43 signals to nuclear factor-κB.
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| Lee SU, In HJ, Kwon MS, Park BO, Jo M, Kim MO, Cho S, Lee S, Lee HJ, Kwak YS, Kim S.
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| Biol Pharm Bull 36(11):1754-9. Epub 2013 Aug 29.
2013
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| 13 | ARRB2
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| Loss of β-arrestin2 mediates pancreatic-islet dysfunction in mice.
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| Zhang M, Zhu Y, Mu K, Li L, Lu J, Zhao J, Huang X, Wang C, Jia W.
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| Biochem Biophys Res Commun 435(3):345-9. doi: 10.1016/j.bbrc.2013.04.079. Epub 2013 May 6.
2013
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| 14 | AGAP2, ARRB1, ARRB2
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| The Arf GAP AGAP2 interacts with β-arrestin2 and regulates β2-adrenergic receptor recycling and ERK activation.
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| Wu Y, Zhao Y, Ma X, Zhu Y, Patel J, Nie Z.
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| Biochem J 452(3):411-21. doi: 10.1042/BJ20121004.
2013
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| 15 | ARRB1, ARRB2
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| β-arrestin-1 participates in thrombosis and regulates integrin aIIbβ3 signalling without affecting P2Y receptors desensitisation and function.
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| Schaff M, Receveur N, Bourdon C, Ohlmann P, Lanza F, Gachet C, Mangin PH.
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| Thromb Haemost 107(4):735-48. doi: 10.1160/TH11-06-0430. Epub 2012 Feb 8.
2012
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| 16 | ARRB2, TRPV1
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| β-Arrestin-2 desensitizes the transient receptor potential vanilloid 1 (TRPV1) channel.
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| Por ED, Bierbower SM, Berg KA, Gomez R, Akopian AN, Wetsel WC, Jeske NA.
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| J Biol Chem 287(44):37552-63. doi: 10.1074/jbc.M112.391847. Epub 2012 Sep 5.
2012
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| 17 | ARRB2
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| β-Arrestin2 mediates the initiation and progression of myeloid leukemia.
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| Fereshteh M, Ito T, Kovacs JJ, Zhao C, Kwon HY, Tornini V, Konuma T, Chen M, Lefkowitz RJ, Reya T.
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| Proc Natl Acad Sci U S A 109(31):12532-7. doi: 10.1073/pnas.1209815109. Epub 2012 Jul 5.
2012
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| 18 | ADRBK1, ARRB2, GRK5
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| Distinct cellular and subcellular distributions of G protein-coupled receptor kinase and arrestin isoforms in the striatum.
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| Bychkov E, Zurkovsky L, Garret MB, Ahmed MR, Gurevich EV.
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| PLoS One 7(11):e48912. doi: 10.1371/journal.pone.0048912. Epub 2012 Nov 6.
2012
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| 19 | ARRB2, CNR1
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| Binding between a distal C-terminus fragment of cannabinoid receptor 1 and arrestin-2.
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| Singh SN, Bakshi K, Mercier RW, Makriyannis A, Pavlopoulos S.
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| Biochemistry 50(12):2223-34. Epub 2011 Feb 28.
2011
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| 20 | ARRB2, MDM2
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| Intact MDM2 E3 ligase activity is required for the cytosolic localization and function of β-arrestin2.
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| Yin C, Zhang R, Xu Y, Chen Q, Xie X.
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| Mol Biol Cell 22(9):1608-16. Epub 2011 Mar 9.
2011
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| 21 | ARRB2, CREB1
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| β-arrestin-2 regulation of the cAMP response element binding protein.
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| Manson ME, Corey DA, Rymut SM, Kelley TJ.
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| Biochemistry 50(27):6022-9. Epub 2011 Jun 15. 2011
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| 22 | ARRB2, RAF1
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| The effect of arrestin conformation on the recruitment of c-Raf1, MEK1, and ERK1/2 activation.
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| Coffa S, Breitman M, Hanson SM, Callaway K, Kook S, Dalby KN, Gurevich VV.
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| PLoS One 6(12):e28723. doi: 10.1371/journal.pone.0028723. Epub 2011 Dec 12.
2011
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| 23 | ARRB1, ARRB2
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| Distinct and shared roles of β-arrestin-1 and β-arrestin-2 on the regulation of C3a receptor signaling in human mast cells.
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| Vibhuti A, Gupta K, Subramanian H, Guo Q, Ali H.
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| PLoS One 6(5):e19585. doi: 10.1371/journal.pone.0019585.
2011
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| 24 | ARR3, ARRB2
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| Non-visual arrestins are constitutively associated with the centrosome and regulate centrosome function.
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| Shankar H, Michal A, Kern RC, Kang DS, Gurevich VV, Benovic JL.
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| J Biol Chem 285(11):8316-29. doi: 10.1074/jbc.M109.062521. Epub 2010 Jan 7.
2010
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| 25 | ARRB2
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| Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer.
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| Lakshmikanthan V, Zou L, Kim JI, Michal A, Nie Z, Messias NC, Benovic JL, Daaka Y.
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| Proc Natl Acad Sci U S A 106(23):9379-84. Epub 2009 May 20.
2009
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| 26 | ARRB2
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| The type III TGF-beta receptor regulates epithelial and cancer cell migration through beta-arrestin2-mediated activation of Cdc42.
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| Mythreye K, Blobe GC.
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| Proc Natl Acad Sci U S A 106(20):8221-6. Epub 2009 May 1.
2009
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| 27 | ARRB2
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| {beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.
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| Ahn S, Kim J, Hara MR, Ren XR, Lefkowitz RJ.
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| J Biol Chem 284(13):8855-65. Epub 2009 Jan 26.PMID: 19171933 2009
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| 28 | ARRB2, C1QA
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| Beta-arrestin 2 is required for complement C1q expression in macrophages and constrains factor-independent survival.
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| Lattin JE, Greenwood KP, Daly NL, Kelly G, Zidar DA, Clark RJ, Thomas WG, Kellie S, Craik DJ, Hume DA, Sweet MJ.
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| Mol Immunol 47(2-3):340-7. doi: 10.1016/j.molimm.2009.09.012. Epub 2009 Sep 26.
2009
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| 29 | ARRB2, CARD10
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| Beta-arrestin 2 is required for lysophosphatidic acid-induced NF-kappaB activation.
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| Sun J, Lin X.
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| Proc Natl Acad Sci U S A 105(44):17085-90. Epub 2008 Oct 24.
2008
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| 30 | ARRB1, ARRB2
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| Beta-arrestin-mediated signaling regulates protein synthesis.
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| DeWire SM, Kim J, Whalen EJ, Ahn S, Chen M, Lefkowitz RJ.
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| J Biol Chem 283(16):10611-20. Epub 2008 Feb 14.PMID: 18276584 2008
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| 31 | ARRB2, ITCH
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| Arrestin-2 Interacts with the Ubiquitin-Protein Isopeptide Ligase Atrophin-interacting Protein 4 and Mediates Endosomal Sorting of the Chemokine Receptor CXCR4.
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| Bhandari D, Trejo J, Benovic JL, Marchese A.
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| J Biol Chem 282(51):36971-9. Epub 2007 Oct 18. 2007
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| 32 | ARRB2, PDE4D
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| Mapping binding sites for the PDE4D5 cAMP-specific phosphodiesterase to the N- and C-domains of beta-arrestin using spot-immobilized peptide arrays.
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| Baillie GS, Adams DR, Bhari N, Houslay TM, Vadrevu S, Meng D, Li X, Dunlop A, Milligan G, Bolger GB, Klussmann E, Houslay MD.
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| Biochem J 404(1):71-80.
2007
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| 33 | ARRB2
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| Beta-arrestin2 enhances beta2-adrenergic receptor-mediated nuclear translocation of ERK.
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| Kobayashi H, Narita Y, Nishida M, Kurose H.
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| Cell Signal 17(10):1248-53. Epub 2005 Feb 12. 2005
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| 34 | ARRB1, ARRB2
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| Beta-arrestin1 and beta-arrestin2 are differentially required for phosphorylation-dependent and -independent internalization of delta-opioid receptors.
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| Zhang X, Wang F, Chen X, Li J, Xiang B, Zhang YQ, Li BM, Ma L.
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| J Neurochem 95(1):169-78. 2005
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| 35 | ARRB1, ARRB2, SLC9A5
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| beta-Arrestins bind and decrease cell-surface abundance of the Na+/H+ exchanger NHE5 isoform.
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| Szabó EZ, Numata M, Lukashova V, Iannuzzi P, Orlowski J.
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| Proc Natl Acad Sci U S A 102(8):2790-5. Epub 2005 Feb 7.PMID: 15699339 2005
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| 36 | ARRB1, ARRB2
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| Beta-arrestin-related proteins in ocular tissues.
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| Nicolas-Leveque C, et al.
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| Invest Ophthalmol Vis Sci 40(8):1812-8 1999
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| 37 | ARRB1, ARRB2, ARR3, SAG
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| The role of receptor kinases and arrestins in G protein-coupled receptor regulation.
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| Krupnick JG, et al.
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| Annu Rev Pharmacol Toxicol 38 : 289-319. 1998
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| 38 | SAG, ADRBK2, ARRB2
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| Chromosome mapping of the human arrestin (SAG), beta-arrestin 2 (ARRB2), and beta-adrenergic receptor kinase 2 (ADRBK2) genes.
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| Calabrese G, et al.
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| Genomics 23 : 286-288. 1994
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| 39 | ARRB2
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| Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms generated by alternative splicing.
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| Parruti G, Peracchia F, Sallese M, Ambrosini G, Masini M, Rotilio D, De Blasi A.
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| J Biol Chem 268(13):9753-61.PMID: 8486659 1993
|