| 1 | ARL6IP5
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| Targeting JWA for Cancer Therapy: Functions, Mechanisms and Drug Discovery.
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| Ding K, Liu X, Wang L, Zou L, Jiang X, Li A, Zhou J.
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| Cancers (Basel) Sep 24;14(19):4655. doi: 10.3390/cancers14194655. 2022
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| 2 | ARL15, ARL6IP5
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| Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis
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| Wu Y, Bai Y, McEwan DG, Bentley L, Aravani D, Cox RD.
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| Biol Open Dec 15;10(12):bio058420. doi: 10.1242/bio.058420. Epub 2021 Dec 13. 2021
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| 3 | ARL6IP5, RAB1A
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| Rab1a rescues the toxicity of PRAF3
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| Oshikane H, Watabe M, Kikuchi-Utsumi K, Nakaki T
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| Biochem Biophys Rep Mar 31;14:16-19. doi: 10.1016/j.bbrep.2018.03.002. 2018
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| 4 | ARL6IP5, POMC
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| GTRAP3-18 regulates food intake and body weight by interacting with pro-opiomelanocortin
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| Aoyama K, Bhadhprasit W, Watabe M, Wang F, Matsumura N, Nakaki T.
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| FASEB J. 32(1):330-341. doi: 10.1096/fj.201700421R. Epub 2017 Sep 13. 2018
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| 5 | ARL6IP5, TNFSF11
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| Overexpression of Arl6ip5 in osteoblast regulates RANKL subcellualr localization.
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| Wu Y, Wang M, Peng Y, Ding Y, Deng L, Fu Q.
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| Biochem Biophys Res Commun. Sep 4;464(4):1275-1281. doi: 10.1016/j.bbrc.2015.07.119. Epub 2015 Jul 26. 2015
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| 6 | ARL6IP5
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| Deficiency of osteoblastic Arl6ip5 impaired osteoblast differentiation and enhanced osteoclastogenesis via disturbance of ER calcium homeostasis and induction of ER stress-mediated apoptosis.
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| Wu Y, Yang M, Fan J, Peng Y, Deng L, Ding Y, Yang R, Zhou J, Miao D, Fu Q.
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| Cell Death Dis. Oct 16;5(10):e1464. doi: 10.1038/cddis.2014.427. 2014
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| 7 | ARL6IP5, TMEFF1
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| Identification of tomoregulin-1 as a novel addicsin-associated factor.
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| Arano T, Fujisaki S, Ikemoto MJ.
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| Neurochem Int. May;71:22-35. doi: 10.1016/j.neuint.2014.03.011. Epub 2014 Mar 26 2014
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| 8 | ARL6IP5, ING4
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| ING4 regulates JWA in angiogenesis and their prognostic value in melanoma patients.
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| Lu J, Tang Y, Cheng Y, Zhang G, Yip A, Martinka M, Dong Z, Zhou J, Li G.
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| Br J Cancer. Nov 26;109(11):2842-52. doi: 10.1038/bjc.2013.670. Epub 2013 Oct 24. 2013
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| 9 | ARL6IP5, OPRD1
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| JWA regulates chronic morphine dependence via the delta opioid receptor.
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| Wu Y, Chen R, Zhao X, Li A, Li G, Zhou J.
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| Biochem Biophys Res Commun 409(3):520-5. Epub 2011 May 11.
2011
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| 10 | ARL6IP5, XRCC1
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| JWA regulates XRCC1 and functions as a novel base excision repair protein in oxidative-stress-induced DNA single-strand breaks.
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| Wang S, Gong Z, Chen R, Liu Y, Li A, Li G, Zhou J.
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| Nucleic Acids Res 37(6):1936-50. Epub 2009 Feb 10.
2009
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| 11 | ARL6IP5, RAB1A
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| GTRAP3-18 serves as a negative regulator of Rab1 in protein transport and neuronal differentiation.
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| Maier S, Reiterer V, Ruggiero AM, Rothstein JD, Thomas S, Dahm R, Sitte HH, Farhan H.
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| J Cell Mol Med 13(1):114-24. Epub 2008 Mar 14.
2009
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| 12 | ARL6IP5
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| The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein.
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| Ruggiero AM, Liu Y, Vidensky S, Maier S, Jung E, Farhan H, Robinson MB, Sitte HH, Rothstein JD.
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| J Biol Chem 283(10):6175-83. Epub 2007 Dec 31. 2008
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| 13 | ARL6IP5, RTN2, SLC1A1
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| Reticulon RTN2B regulates trafficking and function of neuronal glutamate transporter EAAC1.
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| Liu Y, Vidensky S, Ruggiero AM, Maier S, Sitte HH, Rothstein JD.
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| J Biol Chem 283(10):6561-71. Epub 2007 Dec 20. 2008
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| 14 | ARL6IP5
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| A dominant role of GTRAP3-18 in neuronal glutathione synthesis.
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| Watabe M, Aoyama K, Nakaki T.
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| J Neurosci 28(38):9404-13.
2008
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| 15 | ARL6IP1, ARL6IP5, SLC1A1
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| Modulation of the neural glutamate transporter EAAC1 by the addicsin-interacting protein ARL6IP1.
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| Akiduki S, Ikemoto MJ.
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| J Biol Chem 283(46):31323-32. Epub 2008 Aug 6.
2008
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| 16 | ARL6IP5
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| The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/GTRAP3-18 protein.
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| Ruggiero AM, Liu Y, Vidensky S, Maier S, Jung E, Farhan H, Robinson MB, Sitte HH, Rothstein JD.
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| J Biol Chem 283(10):6175-83. Epub 2007 Dec 31.
2008
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| 17 | ARL6IP5
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| JWA as a functional molecule to regulate cancer cells migration via MAPK cascades and F-actin cytoskeleton.
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| Chen H, Bai J, Ye J, Liu Z, Chen R, Mao W, Li A, Zhou J.
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| Cell Signal 19(6):1315-27. Epub 2007 Jan 19.
2007
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| 18 | ARL6IP5
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| JWA, a novel signaling molecule, involved in the induction of differentiation of human myeloid leukemia cells.
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| Huang S, Shen Q, Mao WG, Li AP, Ye J, Liu QZ, Zou CP, Zhou JW.
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| Biochem Biophys Res Commun 341(2):440-50. Epub 2006 Jan 11. 2006
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| 19 | ARL6IP5
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| Regulation of a novel cell differentiation-associated gene, JWA during oxidative damage in K562 and MCF-7 cells.
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| Zhu T, Chen R, Li AP, Liu J, Liu QZ, Chang HC, Zhou JW.
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| J Biomed Sci 12(1):219-27. 2005
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| 20 | PRAF2, ARL6IP5, CCR5
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| JM4 is a four-transmembrane protein binding to the CCR5 receptor.
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| Schweneker M, Bachmann AS, Moelling K.
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| FEBS Lett 579(7):1751-8. 2005
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| 21 | ARL6IP5
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| Molecular cloning, gene structure, expression profile and functional characterization of the mouse glutamate transporter (EAAT3) interacting protein GTRAP3-18.
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| Butchbach ME, Lai L, Lin CL.
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| Gene 292(1-2):81-90.
2002
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| 22 | ARL6IP5, SLC1A1
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| Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18.
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| Lin CI, Orlov I, Ruggiero AM, Dykes-Hoberg M, Lee A, Jackson M, Rothstein JD.
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| Nature 410(6824):84-8. 2001
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