Citations for
1ARL6, TULP3
The molecular machines that traffic signaling receptors into and out of cilia.
Nachury MV.
Curr Opin Cell Biol. Apr;51:124-131. doi: 10.1016/j.ceb.2018.03.004. Epub 2018 Mar 23. 2018
2ARL6, BBS1, BBS9
BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.
Nozaki S, Katoh Y, Kobayashi T, Nakayama K.
PLoS One. Mar 28;13(3):e0195005. doi: 10.1371/journal.pone.0195005. eCollection 2018. 2018
3ARL6
Small GTPase Arl6 controls RH30 rhabdomyosarcoma cell growth through ciliogenesis and Hedgehog signaling.
Liu X, Shen Q, Yu T, Huang H, Zhang Z, Ding J, Tang Y, Xu N, Yue S.
Cell Biosci. Dec 12;6:61. doi: 10.1186/s13578-016-0126-2. eCollection 2016 2016
4ARL6, IFT27
The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV.
Dev Cell 31(3):265-78. doi: 10.1016/j.devcel.2014.09.004. Epub 2014 Oct 30. 2014
5ARL6, BBS1
Structural basis for membrane targeting of the BBSome by ARL6.
Mourão A, Nager AR, Nachury MV, Lorentzen E.
Nat Struct Mol Biol. Dec;21(12):1035-41. doi: 10.1038/nsmb.2920. Epub 2014 Nov 17 2014
6ARL6, BBS1, BBS4, BBS5, PKD1, TTC8
Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.
Su X, Driscoll K, Yao G, Raed A, Wu M, Beales PL, Zhou J.
Hum Mol Genet. 2014
7ARL6, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, LZTFL1, MKKS, MKS1, TTC8, WDPCP
Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization.
Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M, Beales PL.
Hum Mol Genet 22(19):3858-68. doi: 10.1093/hmg/ddt241. Epub 2013 May 27. 2013
8ARL6, BBS3
Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.
Zhang Q, Nishimura D, Seo S, Vogel T, Morgan DA, Searby C, Bugge K, Stone EM, Rahmouni K, Sheffield VC.
Proc Natl Acad Sci U S A. Dec 20;108(51):20678-83. doi: 10.1073/pnas.1113220108. Epub 2011 Dec 2. 2011
9ARL6, BBS3
Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform.
Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield VC, Slusarski DC.
PLoS Genet 6(3):e1000884. 2010
10ARL6, BBS1, BBS10, BBS11, BBS12, BBS14, BBS2, BBS3, BBS4, BBS5, BBS6, BBS7, BBS8, BBS9, CEP290, MKKS, TRIM32, TTC8
Clinical and molecular characterisation of Bardet-Biedl syndrome in consanguineous populations: the power of homozygosity mapping.
Abu Safieh L, Aldahmesh MA, Shamseldin H, Hashem M, Shaheen R, Alkuraya H, Al Hazzaa SA, Al-Rajhi A, Alkuraya FS.
J Med Genet 47(4):236-41. Epub 2009 Oct 26. 2010
11ARL6, BBS3
Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling.
Wiens CJ, Tong Y, Esmail MA, Oh E, Gerdes JM, Wang J, Tempel W, Rattner JB, Katsanis N, Park HW, Leroux MR.
J Biol Chem 285(21):16218-30. Epub 2010 Mar 5.PMID: 20207729 2010
12ARL6, SSTR3
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV.
Cell. 141(7):1208-19. 2010
13ARL6, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, CEP290, MKKS, TRIM32, TTC8
Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.
Seo S, Guo DF, Bugge K, Morgan DA, Rahmouni K, Sheffield VC.
Hum Mol Genet 18(7):1323-31. Epub 2009 Jan 15. 2009
14ARL6, BBS3
Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome.
Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T.
Biochem Biophys Res Commun 381(3):439-42. Epub 2009 Feb 21. 2009
15BBS1, BBS2, ARL6, BBS4, BBS5, MKKS, BBS7, TTC8
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.
Ross AJ, May-Simera H, Eichers ER, Kai M, Hill J, Jagger DJ, Leitch CC, Chapple JP, Munro PM, Fisher S, Tan PL, Phillips HM, Leroux MR, Henderson DJ, Murdoch JN, Copp AJ, Eliot MM, Lupski JR, Kemp DT, Dollfus H, Tada M, Katsanis N, Forge A, Beales PL.
Nat Genet 37(10):1135-40. Epub 2005 Sep 18. 2005
16BBS3, ARL6
Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3).
Chiang AP, Nishimura D, Searby C, Elbedour K, Carmi R, Ferguson AL, Secrist J, Braun T, Casavant T, Stone EM, Sheffield VC.
Am J Hum Genet 75(3):475-84. Epub 2004 Jul 16. 2004
17ARL13B, ARL6, BBS3
Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.
Fan Y, Esmail MA, Ansley SJ, Blacque OE, Boroevich K, Ross AJ, Moore SJ, Badano JL, May-Simera H, Compton DS, Green JS, Lewis RA, van Haelst MM, Parfrey PS, Baillie DL, Beales PL, Katsanis N, Davidson WS, Leroux MR.
Nat Genet 36(9):989-93. Epub 2004 Aug 15. 2004
18ARL6, BBS3
Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3).
Chiang AP, Nishimura D, Searby C, Elbedour K, Carmi R, Ferguson AL, Secrist J, Braun T, Casavant T, Stone EM, Sheffield VC.
Am J Hum Genet 75(3):475-84. Epub 2004 Jul 16. 2004
19ARL6, ARL6IP2, SEC61B, ARL6IP6
A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.
Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP.
FEBS Lett 459(1):69-74. 1999
20ARL4A, ARL6, ARL4C
ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARFfamily characterization by rapid nucleotide exchange and a nuclear localizationsignal.
Jacobs S, Schilf C, Fliegert F, Koling S, Weber Y, Schurmann A, Joost HG.
FEBS Lett 456(3):384-8. 1999