| 1 | ARL6, IFT22
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| Intraflagellar transport protein RABL5/IFT22 recruits the BBSome to the basal body through the GTPase ARL6/BBS3
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| Xue B, Liu YX, Dong B, Wingfield JL, Wu M, Sun J, Lechtreck KF, Fan ZC.
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| Proc Natl Acad Sci U S A. Feb 4;117(5):2496-2505. doi: 10.1073/pnas.1901665117. Epub 2020 Jan 17. 2020
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| 2 | ARL6, TULP3
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| The molecular machines that traffic signaling receptors into and out of cilia.
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| Nachury MV.
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| Curr Opin Cell Biol. Apr;51:124-131. doi: 10.1016/j.ceb.2018.03.004. Epub 2018 Mar 23. 2018
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| 3 | ARL6, BBS1, BBS9
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| BBS1 is involved in retrograde trafficking of ciliary GPCRs in the context of the BBSome complex.
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| Nozaki S, Katoh Y, Kobayashi T, Nakayama K.
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| PLoS One. Mar 28;13(3):e0195005. doi: 10.1371/journal.pone.0195005. eCollection 2018. 2018
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| 4 | ARL6
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| Small GTPase Arl6 controls RH30 rhabdomyosarcoma cell growth through ciliogenesis and Hedgehog signaling.
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| Liu X, Shen Q, Yu T, Huang H, Zhang Z, Ding J, Tang Y, Xu N, Yue S.
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| Cell Biosci. Dec 12;6:61. doi: 10.1186/s13578-016-0126-2. eCollection 2016 2016
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| 5 | ARL6, IFT27
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| The intraflagellar transport protein IFT27 promotes BBSome exit from cilia through the GTPase ARL6/BBS3.
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| Liew GM, Ye F, Nager AR, Murphy JP, Lee JS, Aguiar M, Breslow DK, Gygi SP, Nachury MV.
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| Dev Cell 31(3):265-78. doi: 10.1016/j.devcel.2014.09.004. Epub 2014 Oct 30.
2014
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| 6 | ARL6, BBS1
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| Structural basis for membrane targeting of the BBSome by ARL6.
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| Mourão A, Nager AR, Nachury MV, Lorentzen E.
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| Nat Struct Mol Biol. Dec;21(12):1035-41. doi: 10.1038/nsmb.2920. Epub 2014 Nov 17 2014
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| 7 | ARL6, BBS1, BBS4, BBS5, PKD1, TTC8
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| Bardet-Biedl syndrome proteins 1 and 3 regulate the ciliary trafficking of polycystic kidney disease 1 protein.
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| Su X, Driscoll K, Yao G, Raed A, Wu M, Beales PL, Zhou J.
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| Hum Mol Genet. 2014
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| 8 | ARL6, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, LZTFL1, MKKS, MKS1, TTC8, WDPCP
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| Bardet-Biedl syndrome proteins control the cilia length through regulation of actin polymerization.
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| Hernandez-Hernandez V, Pravincumar P, Diaz-Font A, May-Simera H, Jenkins D, Knight M, Beales PL.
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| Hum Mol Genet 22(19):3858-68. doi: 10.1093/hmg/ddt241. Epub 2013 May 27.
2013
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| 9 | ARL6, BBS3
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| Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes.
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| Zhang Q, Nishimura D, Seo S, Vogel T, Morgan DA, Searby C, Bugge K, Stone EM, Rahmouni K, Sheffield VC.
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| Proc Natl Acad Sci U S A. Dec 20;108(51):20678-83. doi: 10.1073/pnas.1113220108. Epub 2011 Dec 2. 2011
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| 10 | ARL6, BBS3
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| Identification and functional analysis of the vision-specific BBS3 (ARL6) long isoform.
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| Pretorius PR, Baye LM, Nishimura DY, Searby CC, Bugge K, Yang B, Mullins RF, Stone EM, Sheffield VC, Slusarski DC.
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| PLoS Genet 6(3):e1000884.
2010
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| 11 | ARL6, BBS1, BBS10, BBS11, BBS12, BBS14, BBS2, BBS3, BBS4, BBS5, BBS6, BBS7, BBS8, BBS9, CEP290, MKKS, TRIM32, TTC8
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| Clinical and molecular characterisation of Bardet-Biedl syndrome in consanguineous populations: the power of homozygosity mapping.
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| Abu Safieh L, Aldahmesh MA, Shamseldin H, Hashem M, Shaheen R, Alkuraya H, Al Hazzaa SA, Al-Rajhi A, Alkuraya FS.
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| J Med Genet 47(4):236-41. Epub 2009 Oct 26.
2010
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| 12 | ARL6, BBS3
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| Bardet-Biedl syndrome-associated small GTPase ARL6 (BBS3) functions at or near the ciliary gate and modulates Wnt signaling.
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| Wiens CJ, Tong Y, Esmail MA, Oh E, Gerdes JM, Wang J, Tempel W, Rattner JB, Katsanis N, Park HW, Leroux MR.
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| J Biol Chem 285(21):16218-30. Epub 2010 Mar 5.PMID: 20207729 2010
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| 13 | ARL6, SSTR3
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| The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
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| Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV.
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| Cell. 141(7):1208-19. 2010
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| 14 | ARL6, BBS1, BBS10, BBS12, BBS2, BBS4, BBS5, BBS7, BBS9, CEP290, MKKS, TRIM32, TTC8
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| Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling.
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| Seo S, Guo DF, Bugge K, Morgan DA, Rahmouni K, Sheffield VC.
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| Hum Mol Genet 18(7):1323-31. Epub 2009 Jan 15. 2009
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| 15 | ARL6, BBS3
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| Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome.
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| Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T.
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| Biochem Biophys Res Commun 381(3):439-42. Epub 2009 Feb 21.
2009
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| 16 | BBS1, BBS2, ARL6, BBS4, BBS5, MKKS, BBS7, TTC8
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| Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.
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| Ross AJ, May-Simera H, Eichers ER, Kai M, Hill J, Jagger DJ, Leitch CC, Chapple JP, Munro PM, Fisher S, Tan PL, Phillips HM, Leroux MR, Henderson DJ, Murdoch JN, Copp AJ, Eliot MM, Lupski JR, Kemp DT, Dollfus H, Tada M, Katsanis N, Forge A, Beales PL.
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| Nat Genet 37(10):1135-40. Epub 2005 Sep 18. 2005
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| 17 | BBS3, ARL6
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| Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3).
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| Chiang AP, Nishimura D, Searby C, Elbedour K, Carmi R, Ferguson AL, Secrist J, Braun T, Casavant T, Stone EM, Sheffield VC.
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| Am J Hum Genet 75(3):475-84. Epub 2004 Jul 16. 2004
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| 18 | ARL13B, ARL6, BBS3
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| Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome.
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| Fan Y, Esmail MA, Ansley SJ, Blacque OE, Boroevich K, Ross AJ, Moore SJ, Badano JL, May-Simera H, Compton DS, Green JS, Lewis RA, van Haelst MM, Parfrey PS, Baillie DL, Beales PL, Katsanis N, Davidson WS, Leroux MR.
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| Nat Genet 36(9):989-93. Epub 2004 Aug 15. 2004
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| 19 | ARL6, BBS3
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| Comparative genomic analysis identifies an ADP-ribosylation factor-like gene as the cause of Bardet-Biedl syndrome (BBS3).
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| Chiang AP, Nishimura D, Searby C, Elbedour K, Carmi R, Ferguson AL, Secrist J, Braun T, Casavant T, Stone EM, Sheffield VC.
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| Am J Hum Genet 75(3):475-84. Epub 2004 Jul 16.
2004
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| 20 | ARL6, ARL6IP2, SEC61B, ARL6IP6
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| A novel ADP-ribosylation like factor (ARL-6), interacts with the protein-conducting channel SEC61beta subunit.
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| Ingley E, Williams JH, Walker CE, Tsai S, Colley S, Sayer MS, Tilbrook PA, Sarna M, Beaumont JG, Klinken SP.
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| FEBS Lett 459(1):69-74. 1999
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| 21 | ARL4A, ARL6, ARL4C
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| ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARFfamily characterization by rapid nucleotide exchange and a nuclear localizationsignal.
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| Jacobs S, Schilf C, Fliegert F, Koling S, Weber Y, Schurmann A, Joost HG.
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| FEBS Lett 456(3):384-8. 1999
|