| 1 | ARHGEF6, ARHGEF7, GIT1, GIT2
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| Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes.
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| Zhou W, Li X, Premont RT.
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| J Cell Sci 129(10):1963-74. doi: 10.1242/jcs.179465. Review. 2016
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| 2 | ARHGEF7, GIT1, PAK1
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| GIT1/βPIX signaling proteins and PAK1 kinase regulate microtubule nucleation.
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| Černohorská M, Sulimenko V, Hájková Z, Sulimenko T, Sládková V, Vinopal S, Dráberová E, Dráber P.
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| Biochim Biophys Acta 1863(6 Pt A):1282-97. doi: 10.1016/j.bbamcr.2016.03.016.
2016
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| 3 | ARHGEF7, GIT1
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| Microtubule nucleation in mouse bone marrow-derived mast cells is regulated by the concerted action of GIT1/βPIX proteins and calcium.
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| Sulimenko V, Hájková Z, Černohorská M, Sulimenko T, Sládková V, Dráberová L, Vinopal S, Dráberová E, Dráber P.
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| J Immunol 194(9):4099-111. doi: 10.4049/jimmunol.1402459.
2015
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| 4 | ARHGEF7, WWTR1, YAP1
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| Arhgef7 promotes activation of the Hippo pathway core kinase Lats.
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| Heidary Arash E, Song KM, Song S, Shiban A, Attisano L.
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| EMBO J 33(24):2997-3011. doi: 10.15252/embj.201490230.
2014
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| 5 | ARHGEF7, GIT1, PAK1, RAC1
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| GIT1 and βPIX are essential for GABA(A) receptor synaptic stability and inhibitory neurotransmission.
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| Smith KR, Davenport EC, Wei J, Li X, Pathania M, Vaccaro V, Yan Z, Kittler JT.
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| Cell Rep 9(1):298-310. doi: 10.1016/j.celrep.2014.08.061.
2014
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| 6 | ARHGEF7, GIT1, GIT2, RHOJ
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| RhoJ interacts with the GIT-PIX complex and regulates focal adhesion disassembly.
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| Wilson E, Leszczynska K, Poulter NS, Edelmann F, Salisbury VA, Noy PJ, Bacon A, Rappoport JZ, Heath JK, Bicknell R, Heath VL.
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| J Cell Sci 127(Pt 14):3039-51. doi: 10.1242/jcs.140434.
2014
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| 7 | ARHGEF7
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| Hypoxia-induced invadopodia formation: a role for β-PIX.
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| Md Hashim NF, Nicholas NS, Dart AE, Kiriakidis S, Paleolog E, Wells CM.
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| Open Biol 3(6):120159. doi: 10.1098/rsob.120159.
2013
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| 8 | ARHGEF7, GIT1, GRIN3A, RAC1
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| GluN3A expression restricts spine maturation via inhibition of GIT1/Rac1 signaling.
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| Fiuza M, González-González I, Pérez-Otańo I.
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| Proc Natl Acad Sci U S A 110(51):20807-12. doi: 10.1073/pnas.1312211110.
2013
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| 9 | ARHGEF7, FRMPD4, INPP5J
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| Preso regulation of dendritic outgrowth through PI(4,5)P2-dependent PDZ interaction with βPix.
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| Mo J, Lee D, Hong S, Han S, Yeo H, Sun W, Choi S, Kim H, Lee HW.
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| Eur J Neurosci 36(1):1960-70. doi: 10.1111/j.1460-9568.2012.08124.x. Epub 2012 May 17.
2012
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| 10 | ARHGEF7, CALM1
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| A novel calmodulin-β-PIX interaction and its implication in receptor tyrosine kinase regulation.
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| Singh VK, Munro K, Jia Z.
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| Cell Signal 24(9):1790-6. doi: 10.1016/j.cellsig.2012.05.005. Epub 2012 May 12.
2012
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| 11 | ARHGEF7, CTNNB1, SCRIB
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| β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.
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| Sun Y, Bamji SX.
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| J Neurosci 31(47):17123-33. doi: 10.1523/JNEUROSCI.2359-11.2011.
2011
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| 12 | ARHGEF7, SHANK2, SLC9A3
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| BetaPix up-regulates Na+/H+ exchanger 3 through a Shank2-mediated protein-protein interaction.
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| Lee JS, Lee YM, Kim JY, Park HW, Grinstein S, Orlowski J, Kim E, Kim KH, Lee MG.
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| J Biol Chem 285(11):8104-13. Epub 2010 Jan 14.PMID: 20080968 2010
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| 13 | ARHGEF7, GIT1, WASF2
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| BetaPIX and GIT1 regulate HGF-induced lamellipodia formation and WAVE2 transport.
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| Morimura S, Suzuki K, Takahashi K.
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| Biochem Biophys Res Commun 382(3):614-9. Epub 2009 Mar 19.PMID: 19303398 2009
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| 14 | ARHGEF7, GIT1
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| Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly.
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| Schlenker O, Rittinger K.
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| J Mol Biol 386(2):280-9. Epub 2008 Dec 30.
2009
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| 15 | ARHGEF7, DEL13QD, ENFB2
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| Chromosome deletions in 13q33-34: Report of four patients and review of the literature.
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| Walczak-Sztulpa J, Wisniewska M, Latos-Bielenska A, Linn M, Kelbova C, Belitz B, Pfeiffer L, Kalscheuer V, Erdogan F, Kuss AW, Ropers HH, Ullmann R, Tzschach A.
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| Am J Med Genet A 146(3):337-42. PMID: 18203171 [PubMed - in process] 2008
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| 16 | ARHGEF7, GIT1, PAK1, PAK2, SCRIB
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| Scrib regulates PAK activity during the cell migration process.
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| Nola S, Sebbagh M, Marchetto S, Osmani N, Nourry C, Audebert S, Navarro C, Rachel R, Montcouquiol M, Sans N, Etienne-Manneville S, Borg JP, Santoni MJ.
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| Hum Mol Genet 17(22):3552-65. Epub 2008 Aug 20. 2008
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| 17 | ARHGEF6, ARHGEF7, PARVB, RAC1
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| Affixin activates Rac1 via betaPIX in C2C12 myoblast.
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| Matsuda C, Kameyama K, Suzuki A, Mishima W, Yamaji S, Okamoto H, Nishino I, Hayashi YK.
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| FEBS Lett 582(8):1189-96. Epub 2008 Mar 4.PMID: 18325335 2008
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| 18 | ARHGEF7
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| Role of phospholipase Cgamma1 in cell spreading requires association with a beta-Pix/GIT1-containing complex, leading to activation of Cdc42 and Rac1.
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| Jones NP, Katan M.
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| Mol Cell Biol 27(16):5790-805. Epub 2007 Jun 11. 2007
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| 19 | SH2D1A, ARHGEF6, ARHGEF7
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| The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation.
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| Gu C, Tangye SG, Sun X, Luo Y, Lin Z, Wu J.
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| Proc Natl Acad Sci U S A 103(39):14447-52. Epub 2006 Sep 18. 2006
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| 20 | ARHGEF7, NOX1, NOXO1
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| Molecular interaction of NADPH oxidase 1 with betaPix and Nox Organizer 1.
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| Park HS, Park D, Bae YS.
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| Biochem Biophys Res Commun 339(3):985-90. 2006
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| 21 | ARHGEF6, ARHGEF7, PARVB, RAC1
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| Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling.
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| Rosenberger G, Jantke I, Gal A, Kutsche K.
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| Hum Mol Genet 12(2):155-67.PMID: 12499396 2003
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| 22 | ARHGEF7
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| Genomic structure of the human beta-PIX gene and its alteration in gastric cancer.
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| Li Z, Wang Y, Song J, Kataoka H, Yoshii S, Gao C, Wang Y, Zhou J, Ota S, Tanaka M, Sugimura H.
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| Cancer Lett 177(2):203-8. 2002
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| 23 | ARHGEF6, ARHGEF7
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| PAK kinases are directly coupled to the PIX family of nucleotide exchange factors.
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| Manser E, Loo TH, Koh CG, Zhao ZS, Chen XQ, Tan L, Tan I, Leung T, Lim L.
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| Mol Cell 1(2):183-92. 1998
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| 24 | ARHGEF7
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| A novel regulator of p21-activated kinases.
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| Bagrodia S, Taylor SJ, Jordon KA, Van Aelst L, Cerione RA.
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| J Biol Chem 273(37):23633-6. 1998
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| 25 | ARHGEF7
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| Cloning of a SH3 domain-containing proline-rich protein, p85SPR, and its localization in focal adhesion.
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| Oh WK, Yoo JC, Jo D, Song YH, Kim MG, Park D.
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| Biochem Biophys Res Commun 235(3):794-8. 1997
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