1 | ARHGEF18, SEPTIN9
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| Septin-mediated RhoA activation engages the exocyst complex to recruit the cilium transition zone. 2023 PMID:
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| Safavian D, Kim MS, Xie H, El-Zeiry M, Palander O, Dai L, Collins RF, Froese C, Shannon R, Nagata KI, Trimble WS.
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| J Cell Biol. Apr 3;222(4):e201911062. doi: 10.1083/jcb.201911062. Epub 2023 Mar 13. 2023
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2 | ARHGEF18
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| ARHGEF18/p114RhoGEF Coordinates PKA/CREB Signaling and Actomyosin Remodeling to Promote Trophoblast Cell-Cell Fusion During Placenta Morphogenesis.
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| Beal R, Alonso-Carriazo Fernandez A, Grammatopoulos DK, Matter K, Balda MS.
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| Front Cell Dev Biol. Mar 25;9:658006. doi: 10.3389/fcell.2021.658006. 2021
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3 | ARHGEF18
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| Rho Guanine Nucleotide Exchange Factors Regulate Horizontal Axon Branching of Cortical Upper Layer Neurons
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| Yamamori T, Watakabe A, Yamamoto N.
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| Cereb Cortex. Apr 14;30(4):2506-2518. doi: 10.1093/cercor/bhz256. 2020
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4 | ARHGEF18
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| Expression of novel "LOCGEF" isoforms of ARHGEF18 in eosinophils.
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| Turton KB, Wilkerson EM, Hebert AS, Fogerty FJ, Schira HM, Botros FE, Coon JJ, Mosher DF.
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| J Leukoc Biol. Jul;104(1):135-145. doi: 10.1002/JLB.2MA1017-418RR. Epub 2018 Mar 30 2018
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5 | ARHGEF18, ARRP21, CRB1, RP12
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| Biallelic Mutation of ARHGEF18, Involved in the Determination of Epithelial Apicobasal Polarity, Causes Adult-Onset Retinal Degeneration.
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| Arno G, Carss KJ, Hull S, Zihni C, Robson AG, Fiorentino A; UK Inherited Retinal Disease Consortium.
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| Am J Hum Genet 100(2):334-342. doi: 10.1016/j.ajhg.2016.12.014.
2017
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6 | ARHGEF18
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| p114RhoGEF governs cell motility and lumen formation during tubulogenesis through a ROCK-myosin-II pathway.
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| Kim M, M Shewan A, Ewald AJ, Werb Z, Mostov KE.
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| J Cell Sci. Dec 1;128(23):4317-27. doi: 10.1242/jcs.172361. Epub 2015 Oct 19. 2015
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7 | ARHGEF18, RHOA, ROCK2
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| ArhGEF18 regulates RhoA-Rock2 signaling to maintain neuro-epithelial apico-basal polarity and proliferation.
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| Herder C, Swiercz JM, Müller C, Peravali R, Quiring R, Offermanns S, Wittbrodt J, Loosli F.
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| Development 140(13):2787-97. doi: 10.1242/dev.096487.
2013
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8 | ARHGEF18, RHOA, ROCK2
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| ArhGEF18 regulated Rho signaling in vertebrate retina development.
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| Loosli F.
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| Small GTPases 4(4):242-6. doi: 10.4161/sgtp.27061. Review.
2013
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9 | ARHGEF18, STK11
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| LKB1 controls human bronchial epithelial morphogenesis through p114RhoGEF-dependent RhoA activation.
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| Xu X, Jin D, Durgan J, Hall A.
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| Mol Cell Biol 33(14):2671-82. doi: 10.1128/MCB.00154-13.
2013
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10 | ARHGEF18
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| Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion.
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| Terry SJ, Elbediwy A, Zihni C, Harris AR, Bailly M, Charras GT, Balda MS, Matter K.
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| PLoS One 7(11):e50188. doi: 10.1371/journal.pone.0050188.
2012
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11 | ARHGEF18, EPB41L4B
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| Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF.
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| Nakajima H, Tanoue T.
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| J Cell Biol 195(2):245-61.
2011
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12 | ARHGEF18
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| Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis.
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| Terry SJ, Zihni C, Elbediwy A, Vitiello E, Leefa Chong San IV, Balda MS, Matter K.
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| Nat Cell Biol 13(2):159-66. Epub 2011 Jan 23.
2011
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13 | ARHGEF18, GNB1, GNG2
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| G Protein betagamma subunits stimulate p114RhoGEF, a guanine nucleotide exchange factor for RhoA and Rac1: regulation of cell shape and reactive oxygen species production.
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| Niu J, Profirovic J, Pan H, Vaiskunaite R, Voyno-Yasenetskaya T.
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| Circ Res 93(9):848-56. Epub 2003 Sep 25.
2003
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14 | ARHGEF18
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| Identification and characterization of a novel Rho-specific guanine nucleotide exchange factor.
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| Blomquist A, Schworer G, Schablowski H, Psoma A, Lehnen M, Jakobs KH, Rumenapp U.
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| Biochem J 352 Pt 2:319-25. 2000
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