1 | ARHGAP35, PLXNB2, RND3
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| An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.
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| Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F.
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| Nat Commun 5:3405. doi: 10.1038/ncomms4405.
2014
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2 | ARHGAP35, ARHGAP5, CTNND1
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| Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability.
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| Zebda N, Tian Y, Tian X, Gawlak G, Higginbotham K, Reynolds AB, Birukova AA, Birukov KG.
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| J Biol Chem 288(25):18290-9. doi: 10.1074/jbc.M112.432757. Epub 2013 May 7. 2013
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3 | ARHGAP35
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| p190A RhoGAP is involved in EGFR pathways and promotes proliferation, invasion and migration in lung adenocarcinoma cells.
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| Notsuda H, Sakurada A, Endo C, Okada Y, Horii A, Shima H, Kondo T.
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| Int J Oncol 43(5):1569-77. doi: 10.3892/ijo.2013.2096. Epub 2013 Sep 13.
2013
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4 | ARHGAP35
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| p190RhoGAP has cellular RacGAP activity regulated by a polybasic region.
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| Lévay M, Bartos B, Ligeti E.
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| Cell Signal 25(6):1388-94. doi: 10.1016/j.cellsig.2013.03.004. Epub 2013 Mar 14.
2013
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5 | ARHGAP35, PLEKHG5, RND1, RND2, RND3
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| The GTPase-deficient Rnd proteins are stabilized by their effectors.
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| Goh LL, Manser E.
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| J Biol Chem 287(37):31311-20. doi: 10.1074/jbc.M111.327056. Epub 2012 Jul 17. 2012
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6 | ARHGAP35, RND1, RND2, RND3
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| Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation.
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| Oinuma I, Kawada K, Tsukagoshi K, Negishi M.
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| Mol Biol Cell 23(8):1593-604. doi: 10.1091/mbc.E11-11-0900. Epub 2012 Feb 22.
2012
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7 | ARHGAP35, GIT1, MAGI1, PTPRZ1
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| Consensus substrate sequence for protein-tyrosine phosphatase receptor type Z.
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| Fujikawa A, Fukada M, Makioka Y, Suzuki R, Chow JP, Matsumoto M, Noda M.
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| J Biol Chem 286(43):37137-46. doi: 10.1074/jbc.M111.270140. Epub 2011 Sep 2. 2011
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8 | ARHGAP35
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| Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis.
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| Manchinelly SA, Miller JA, Su L, Miyake T, Palmer L, Mikawa M, Parsons SJ.
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| J Biol Chem 285(35):26923-32. doi: 10.1074/jbc.M110.103804. Epub 2010 Jun 9.
2010
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9 | ARHGAP35
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| Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.
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| Pullikuth AK, Catling AD.
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| Mol Cell Biol 30(13):3233-48. doi: 10.1128/MCB.01178-09. Epub 2010 May 3.
2010
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10 | AFAP1, ARHGAP35, SH3PXD2A
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| Tks5 recruits AFAP-110, p190RhoGAP, and cortactin for podosome formation.
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| Crimaldi L, Courtneidge SA, Gimona M.
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| Exp Cell Res 315(15):2581-92. Epub 2009 Jun 18. 2009
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11 | ARHGAP35, PTK2, RASA1
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| A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.
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| Tomar A, Lim ST, Lim Y, Schlaepfer DD.
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| J Cell Sci 122(Pt 11):1852-62. Epub 2009 May 12. Erratum in: J Cell Sci. 2009 Aug 15;122(Pt 16):3005. PMID: 1943580 2009
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12 | ARHGAP35, PTK6, RASA1
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| Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.
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| Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH.
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| Cancer Res 68(19):7779-87.PMID: 18829532 2008
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13 | ARHGAP35, ECT2
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| Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis.
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| Mikawa M, Su L, Parsons SJ.
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| Cell Cycle 7(13):2003-12.PMID: 18642445 2008
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14 | ARHGAP35
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| Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.
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| Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP.
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| J Biol Chem 282(33):23910-8. Epub 2007 Jun 11.PMID: 17562701 2007
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15 | ARHGAP35, CTNND1
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| p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.
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| Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB.
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| Cell 127(5):1027-39. 2006
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16 | ARHGAP35, RASA1
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| Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.
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| Bradley WD, Hernández SE, Settleman J, Koleske AJ.
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| Mol Biol Cell 17(11):4827-36. Epub 2006 Sep 13.PMID: 16971514 2006
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17 | ARHGAP35
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| p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas.
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| Tikoo A, Czekay S, Viars C, White S, Heath JK, Arden K, Maruta H.
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| Gene 257(1):23-31. 2000
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