Citations for
1ARHGAP35, PLXNB2, RND3
An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration.
Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F.
Nat Commun 5:3405. doi: 10.1038/ncomms4405. 2014
2ARHGAP35, ARHGAP5, CTNND1
Interaction of p190RhoGAP with C-terminal domain of p120-catenin modulates endothelial cytoskeleton and permeability.
Zebda N, Tian Y, Tian X, Gawlak G, Higginbotham K, Reynolds AB, Birukova AA, Birukov KG.
J Biol Chem 288(25):18290-9. doi: 10.1074/jbc.M112.432757. Epub 2013 May 7. 2013
3ARHGAP35
p190A RhoGAP is involved in EGFR pathways and promotes proliferation, invasion and migration in lung adenocarcinoma cells.
Notsuda H, Sakurada A, Endo C, Okada Y, Horii A, Shima H, Kondo T.
Int J Oncol 43(5):1569-77. doi: 10.3892/ijo.2013.2096. Epub 2013 Sep 13. 2013
4ARHGAP35
p190RhoGAP has cellular RacGAP activity regulated by a polybasic region.
Lévay M, Bartos B, Ligeti E.
Cell Signal 25(6):1388-94. doi: 10.1016/j.cellsig.2013.03.004. Epub 2013 Mar 14. 2013
5ARHGAP35, PLEKHG5, RND1, RND2, RND3
The GTPase-deficient Rnd proteins are stabilized by their effectors.
Goh LL, Manser E.
J Biol Chem 287(37):31311-20. doi: 10.1074/jbc.M111.327056. Epub 2012 Jul 17. 2012
6ARHGAP35, RND1, RND2, RND3
Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation.
Oinuma I, Kawada K, Tsukagoshi K, Negishi M.
Mol Biol Cell 23(8):1593-604. doi: 10.1091/mbc.E11-11-0900. Epub 2012 Feb 22. 2012
7ARHGAP35, GIT1, MAGI1, PTPRZ1
Consensus substrate sequence for protein-tyrosine phosphatase receptor type Z.
Fujikawa A, Fukada M, Makioka Y, Suzuki R, Chow JP, Matsumoto M, Noda M.
J Biol Chem 286(43):37137-46. doi: 10.1074/jbc.M111.270140. Epub 2011 Sep 2. 2011
8ARHGAP35
Mitotic down-regulation of p190RhoGAP is required for the successful completion of cytokinesis.
Manchinelly SA, Miller JA, Su L, Miyake T, Palmer L, Mikawa M, Parsons SJ.
J Biol Chem 285(35):26923-32. doi: 10.1074/jbc.M110.103804. Epub 2010 Jun 9. 2010
9ARHGAP35
Extracellular signal-regulated kinase promotes Rho-dependent focal adhesion formation by suppressing p190A RhoGAP.
Pullikuth AK, Catling AD.
Mol Cell Biol 30(13):3233-48. doi: 10.1128/MCB.01178-09. Epub 2010 May 3. 2010
10AFAP1, ARHGAP35, SH3PXD2A
Tks5 recruits AFAP-110, p190RhoGAP, and cortactin for podosome formation.
Crimaldi L, Courtneidge SA, Gimona M.
Exp Cell Res 315(15):2581-92. Epub 2009 Jun 18. 2009
11ARHGAP35, PTK2, RASA1
A FAK-p120RasGAP-p190RhoGAP complex regulates polarity in migrating cells.
Tomar A, Lim ST, Lim Y, Schlaepfer DD.
J Cell Sci 122(Pt 11):1852-62. Epub 2009 May 12. Erratum in: J Cell Sci. 2009 Aug 15;122(Pt 16):3005. PMID: 1943580 2009
12ARHGAP35, PTK6, RASA1
Breast tumor kinase phosphorylates p190RhoGAP to regulate rho and ras and promote breast carcinoma growth, migration, and invasion.
Shen CH, Chen HY, Lin MS, Li FY, Chang CC, Kuo ML, Settleman J, Chen RH.
Cancer Res 68(19):7779-87.PMID: 18829532 2008
13ARHGAP35, ECT2
Opposing roles of p190RhoGAP and Ect2 RhoGEF in regulating cytokinesis.
Mikawa M, Su L, Parsons SJ.
Cell Cycle 7(13):2003-12.PMID: 18642445 2008
14ARHGAP35
Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.
Mammoto T, Parikh SM, Mammoto A, Gallagher D, Chan B, Mostoslavsky G, Ingber DE, Sukhatme VP.
J Biol Chem 282(33):23910-8. Epub 2007 Jun 11.PMID: 17562701 2007
15ARHGAP35, CTNND1
p120-catenin and p190RhoGAP regulate cell-cell adhesion by coordinating antagonism between Rac and Rho.
Wildenberg GA, Dohn MR, Carnahan RH, Davis MA, Lobdell NA, Settleman J, Reynolds AB.
Cell 127(5):1027-39. 2006
16ARHGAP35, RASA1
Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane.
Bradley WD, Hernández SE, Settleman J, Koleske AJ.
Mol Biol Cell 17(11):4827-36. Epub 2006 Sep 13.PMID: 16971514 2006
17ARHGAP35
p190-A, a human tumor suppressor gene, maps to the chromosomal region 19q13.3 that is reportedly deleted in some gliomas.
Tikoo A, Czekay S, Viars C, White S, Heath JK, Arden K, Maruta H.
Gene 257(1):23-31. 2000