| 1 | AR, SMAD4
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| AR cooperates with SMAD4 to maintain skeletal muscle homeostasis. 2022PMID:
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| Forouhan M, Lim WF, Zanetti-Domingues LC, Tynan CJ, Roberts TC, Malik B, Manzano R, Speciale AA, Ellerington R, Garcia-Guerra A, Fratta P, Sorarú G, Greensmith L, Pennuto M, Wood MJA, Rinaldi C
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| Acta Neuropathol. Jun;143(6):713-731. doi: 10.1007/s00401-022-02428-1. Epub 2022 May 6. 2022
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| 2 | AR, PCDH7
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| Effect of aberrantly methylated androgen receptor target gene PCDH7 on the development of androgen-independent prostate cancer cells.
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| Xu S, Wu X, Tao Z, Li H, Fan C, Chen S, Guo J, Ning Y, Hu X.
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| Genes Genomics 42(3):299-307. doi: 10.1007/s13258-019-00903-w. Epub 2019 Dec 23.
2020
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| 3 | AR, SLIRP
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| Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen
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| De Silva D, Zhang Z, Liu Y, Parker JS, Xu C, Cai L, Wang GG, Earp HS, Whang YE.
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| Sci Rep. Dec 9;9(1):18637. doi: 10.1038/s41598-019-55057-2. 2019
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| 4 | AR, XPO1
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| Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression.
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| Aboukameel A, Muqbil I, Baloglu E, Senapedis W, Landesman Y, Argueta C, Kauffman M, Chang H, Kashyap T, Shacham S, Neggers JE, Daelemans D, Heath EI, Azmi AS.
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| Oncotarget 9(82):35327-35342. doi: 10.18632/oncotarget.26239. eCollection 2018 Oct 19.
2018
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| 5 | AR, NR2E1
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| Orphan nuclear receptor TLX contributes to androgen insensitivity in castration-resistant prostate cancer via its repression of androgen receptor transcription.
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| Jia L, Wu D, Wang Y, You W, Wang Z, Xiao L, Cai G, Xu Z, Zou C, Wang F, Teoh JY, Ng CF, Yu S, Chan FL.
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| Oncogene. Jun;37(25):3340-3355. doi: 10.1038/s41388-018-0198-z. Epub 2018 Mar 20. 2018
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| 6 | AR, DHX15, SIAH2
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| DHX15 promotes prostate cancer progression by stimulating Siah2-mediated ubiquitination of androgen receptor.
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| Jing Y, Nguyen MM, Wang D, Pascal LE, Guo W, Xu Y, Ai J, Deng FM, Masoodi KZ, Yu X, Zhang J, Nelson JB, Xia S, Wang Z.
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| Oncogene oncogene. 2017 Oct 9. doi: 10.1038/onc.2017.371. [Epub ahead of print] 2017
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| 7 | AR, FOXA1, GATA2, SEMA3C
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| Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.
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| Tam KJ, Dalal K, Hsing M, Cheng CW, Khosravi S, Yenki P, Tse C, Peacock JW, Sharma A, Chiang YT, Wang Y, Cherkasov A, Rennie PS, Gleave ME, Ong CJ.
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| Oncotarget 8(6):9617-9633. doi: 10.18632/oncotarget.14168.
2017
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| 8 | AR, SRARP
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| C1orf64 is a novel androgen receptor target gene and coregulator that interacts with 14-3-3 protein in breast cancer
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| Naderi A.
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| Oncotarget. May 11;8(34):57907-57933. doi: 10.18632/oncotarget.17826. 2017
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| 9 | AR, CACUL1
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| CACUL1 functions as a negative regulator of androgen receptor in prostate cancer cells.
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| Choi H, Lee SH, Um SJ, Kim EJ.
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| Cancer Lett 376(2):360-6. doi: 10.1016/j.canlet.2016.04.019. Epub 2016 Apr 13. 2016
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| 10 | AR, ING1, ING2
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| A novel crosstalk between the tumor suppressors ING1 and ING2 regulates androgen receptor signaling.
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| Esmaeili M, Pungsrinont T, Schaefer A, Baniahmad A.
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| J Mol Med (Berl) 94(10):1167-1179. Epub 2016 Jun 16.
2016
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| 11 | AR, ING1
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| The tumor suppressor ING1b is a novel corepressor for the androgen receptor and induces cellular senescence in prostate cancer cells.
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| Esmaeili M, Jennek S, Ludwig S, Klitzsch A, Kraft F, Melle C, Baniahmad A.
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| J Mol Cell Biol 8(3):207-20. doi: 10.1093/jmcb/mjw007. Epub 2016 Mar 18.
2016
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| 12 | AR, BCAS2, HSP90AB1
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| BCAS2 promotes prostate cancer cells proliferation by enhancing AR mRNA transcription and protein stability.
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| Kuo PC, Huang CW, Lee CI, Chang HW, Hsieh SW, Chung YP, Lee MS, Huang CS, Tsao LP, Tsao YP, Chen SL.
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| Br J Cancer 112(2):391-402. doi: 10.1038/bjc.2014.603. Epub 2014 Dec 2.
2015
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| 13 | AR, MLXIPL
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| Chrebp regulates the transcriptional activity of androgen receptor in prostate cancer.
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| Wang XL, Wen XF, Li RB, Liu B, Qiu GM, Wen JL, Wang YM.
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| Tumour Biol 35(8):8143-8. doi: 10.1007/s13277-014-2085-8. Epub 2014 May 21.
2014
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| 14 | AR, GATA2
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| GATA2 facilitates steroid receptor coactivator recruitment to the androgen receptor complex.
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| He B, Lanz RB, Fiskus W, Geng C, Yi P, Hartig SM, Rajapakshe K, Shou J, Wei L, Shah SS, Foley C, Chew SA, Eedunuri VK, Bedoya DJ, Feng Q, Minami T, Mitsiades CS, Frolov A, Weigel NL, Hilsenbeck SG, Rosen DG, Palzkill T, Ittmann MM, Song Y, Coarfa C, O'Malley BW, Mitsiades N.
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| Proc Natl Acad Sci U S A 111(51):18261-6. doi: 10.1073/pnas.1421415111.
2014
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| 15 | AR, ELF3
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| ELF3 is a repressor of androgen receptor action in prostate cancer cells.
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| Shatnawi A, Norris JD, Chaveroux C, Jasper JS, Sherk AB, McDonnell DP, Gigučre V.
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| Oncogene ncogene. 2013 Feb 25. doi: 10.1038/onc.2013.15. [Epub ahead of print]
2013
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| 16 | AR, UBE2B
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| Identification of Ube2b as a novel target of androgen receptor in mouse sertoli cells.
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| Mou L, Zhang Q, Wang Y, Zhang Q, Sun L, Li C, Huang W, Yuan Y, Duan Y, Diao R, Jiang Z, Ye J, Cai Z, Gui Y.
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| Biol Reprod 89(2):32. doi: 10.1095/biolreprod.112.103648. Print 2013 Aug.
2013
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| 17 | AR, ERG, SOX9
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| ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.
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| Cai C, Wang H, He HH, Chen S, He L, Ma F, Mucci L, Wang Q, Fiore C, Sowalsky AG, Loda M, Liu XS, Brown M, Balk SP, Yuan X.
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| J Clin Invest 123(3):1109-22. doi: 10.1172/JCI66666. Epub 2013 Feb 15.
2013
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| 18 | AR, IPO7
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| Androgen induces a switch from cytoplasmic retention to nuclear import of the androgen receptor.
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| Ni L, Llewellyn R, Kesler CT, Kelley JB, Spencer A, Snow CJ, Shank L, Paschal BM.
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| Mol Cell Biol 33(24):4766-78. doi: 10.1128/MCB.00647-13. Epub 2013 Oct 7.
2013
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| 19 | AR, MAGEA11
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| Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers.
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| Minges JT, Su S, Grossman G, Blackwelder AJ, Pop EA, Mohler JL, Wilson EM.
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| J Biol Chem 288(3):1939-52. doi: 10.1074/jbc.M112.428409. Epub 2012 Nov 21.
2013
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| 20 | AR, USP12, WDR20, WDR48
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| Deubiquitinating enzyme Usp12 is a novel co-activator of the androgen receptor.
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| Burska UL, Harle VJ, Coffey K, Darby S, Ramsey H, O'Neill D, Logan IR, Gaughan L, Robson CN.
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| J Biol Chem 288(45):32641-50. doi: 10.1074/jbc.M113.485912. Epub 2013 Sep 21. 2013
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| 21 | AR, WDR77
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| Functional domains of androgen receptor coactivator p44/Mep50/WDR77and its interaction with Smad1.
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| Li Y, Tian L, Ligr M, Daniels G, Peng Y, Wu X, Singh M, Wei J, Shao Y, Lepor H, Xu R, Chang Z, Wang Z, Lee P.
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| PLoS One 8(5):e64663. doi: 10.1371/journal.pone.0064663. Print 2013.
2013
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| 22 | AR, MAZ
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| The prostate cancer-up-regulated Myc-associated zinc-finger protein (MAZ) modulates proliferation and metastasis through reciprocal regulation of androgen receptor.
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| Jiao L, Li Y, Shen D, Xu C, Wang L, Huang G, Chen L, Yang Y, Yang C, Yu Y, Sun Y.
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| Med Oncol 30(2):570. doi: 10.1007/s12032-013-0570-3. Epub 2013 Apr 23.
2013
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| 23 | AR, CCL4, STAT3
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| Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling.
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| Fang LY, Izumi K, Lai KP, Liang L, Li L, Miyamoto H, Lin WJ, Chang C.
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| Cancer Res 73(18):5633-46. doi: 10.1158/0008-5472.CAN-12-3228. Epub 2013 Jul 22.
2013
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| 24 | AR
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| Androgen receptor association with mitotic chromatin - analysis with introduced deletions and disease-inflicting mutations.
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| Kumar S, Tyagi RK.
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| FEBS J 279(24):4598-614. doi: 10.1111/febs.12046. Epub 2012 Nov 23.
2012
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| 25 | AIS, AR
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| Androgen insensitivity syndrome.
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| Hughes IA, Werner R, Bunch T, Hiort O.
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| Semin Reprod Med 30(5):432-42. doi: 10.1055/s-0032-1324728. Epub 2012 Oct 8. Review.
2012
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| 26 | AR
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| Nuclear export signal of androgen receptor (NESAR) regulation of androgen receptor level in human prostate cell lines via ubiquitination and proteasome-dependent degradation.
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| Gong Y, Wang D, Dar JA, Singh P, Graham L, Liu W, Ai J, Xin Z, Guo Y, Wang Z.
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| Endocrinology 153(12):5716-25. doi: 10.1210/en.2012-1841. Epub 2012 Oct 5.
2012
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| 27 | AR
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| Dynamic SUMOylation is linked to the activity cycles of androgen receptor in the cell nucleus.
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| Rytinki M, Kaikkonen S, Sutinen P, Paakinaho V, Rahkama V, Palvimo JJ.
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| Mol Cell Biol 32(20):4195-205. Epub 2012 Aug 13.
2012
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| 28 | AR, DDB2
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| DDB2 is a novel AR interacting protein and mediates AR ubiquitination/degradation.
|
| Chang SW, Su CH, Chen HH, Huang CW, Tsao LP, Tsao YP, Chen SL.
|
| Int J Biochem Cell Biol 44(11):1952-61. doi: 10.1016/j.biocel.2012.07.023. Epub 2012 Jul 28.
2012
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| 29 | AR, CCT6A
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| Polyglutamined expanded androgen receptor interacts with chaperonin CCT.
|
| Pongtepaditep S, Limjindaporn T, Lertrit P, Srisawat C, Limwongse C.
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| Eur J Med Genet 55(11):599-604. doi: 10.1016/j.ejmg.2012.06.013. Epub 2012 Jul 14.
2012
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| 30 | AR, ATF3
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| The stress response mediator ATF3 represses androgen signaling by binding the androgen receptor.
|
| Wang H, Jiang M, Cui H, Chen M, Buttyan R, Hayward SW, Hai T, Wang Z, Yan C.
|
| Mol Cell Biol 32(16):3190-202. doi: 10.1128/MCB.00159-12. Epub 2012 Jun 4.
2012
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| 31 | AR
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| Androgen receptor CAG and GGN polymorphisms in boys with isolated hypospadias.
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| Parada-Bustamante A, Lardone MC, Madariaga M, Johnson MC, Codner E, Cassorla F, Castro A.
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| J Pediatr Endocrinol Metab 25(1-2):157-62.
2012
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| 32 | AIS, AR
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| A large deletion/insertion-induced frameshift mutation of the androgen receptor gene in a family with a familial complete androgen insensitivity syndrome.
|
| Cong P, Ye Y, Wang Y, Lu L, Yong J, Yu P, Joseph KK, Jin F, Qi M.
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| Gene 500(2):220-3. doi: 10.1016/j.gene.2012.02.028. Epub 2012 Mar 31.
2012
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| 33 | AR, ZEB1
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| Androgen receptor is overexpressed in boys with severe hypospadias, and ZEB1 regulates androgen receptor expression in human foreskin cells.
|
| Qiao L, Tasian GE, Zhang H, Cao M, Ferretti M, Cunha GR, Baskin LS.
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| Pediatr Res 71(4 Pt 1):393-8. doi: 10.1038/pr.2011.49. Epub 2012 Jan 6.
2012
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| 34 | AR
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| Differential expression and function of AR isoforms in prostate cancer.
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| Zeng R, Liu Z, Sun Y, Xu C.
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| Oncol Rep 27(2):492-8. doi: 10.3892/or.2011.1516. Epub 2011 Oct 21.
2012
|
| 35 | AR, MED1
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| Regulation of androgen receptor-dependent transcription by coactivator MED1 is mediated through a newly discovered noncanonical binding motif.
|
| Jin F, Claessens F, Fondell JD.
|
| J Biol Chem 287(2):858-70. doi: 10.1074/jbc.M111.304519. Epub 2011 Nov 18.
2012
|
| 36 | AR, MAGEA11
|
| Androgen receptor exon 1 mutation causes androgen insensitivity by creating phosphorylation site and inhibiting melanoma antigen-A11 activation of NH2- and carboxyl-terminal interaction-dependent transactivation.
|
| Lagarde WH, Blackwelder AJ, Minges JT, Hnat AT, French FS, Wilson EM.
|
| J Biol Chem 287(14):10905-15. doi: 10.1074/jbc.M111.336081. Epub 2012 Feb 13.
2012
|
| 37 | AR, NR4A1
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| Testicular steroidogenesis is locally regulated by androgen via suppression of Nur77.
|
| Song CH, Gong EY, Park Js, Lee K.
|
| Biochem Biophys Res Commun 422(2):327-32. doi: 10.1016/j.bbrc.2012.04.161. Epub 2012 May 7.
2012
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| 38 | AR, PAXIP1
|
| A polyglutamine expansion disease protein sequesters PTIP to attenuate DNA repair and increase genomic instability.
|
| Xiao H, Yu Z, Wu Y, Nan J, Merry DE, Sekiguchi JM, Ferguson DO, Lieberman AP, Dressler GR.
|
| Hum Mol Genet 21(19):4225-36. doi: 10.1093/hmg/dds246. Epub 2012 Jun 26.
2012
|
| 39 | AR, GLI1
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| GLI1, a crucial mediator of sonic hedgehog signaling in prostate cancer, functions as a negative modulator for androgen receptor.
|
| Chen G, Goto Y, Sakamoto R, Tanaka K, Matsubara E, Nakamura M, Zheng H, Lu J, Takayanagi R, Nomura M.
|
| Biochem Biophys Res Commun 404(3):809-15. Epub 2010 Dec 21.
2011
|
| 40 | AR, BTG2
|
| BTG2 is an LXXLL-dependent co-repressor for androgen receptor transcriptional activity.
|
| Hu XD, Meng QH, Xu JY, Jiao Y, Ge CM, Jacob A, Wang P, Rosen EM, Fan S.
|
| Biochem Biophys Res Commun 404(4):903-9. Epub 2010 Dec 21.
2011
|
| 41 | AR, DNMT1
|
| Repression of androgen receptor transcription through the E2F1/DNMT1 axis.
|
| Valdez CD, Davis JN, Odeh HM, Layfield TL, Cousineau CS, Berton TR, Johnson DG, Wojno KJ, Day ML.
|
| PLoS One 6(9):e25187. doi: 10.1371/journal.pone.0025187. Epub 2011 Sep 26.
2011
|
| 42 | AR
|
| Evidence for epigenetic abnormalities of the androgen receptor gene in foreskin from children with hypospadias.
|
| Vottero A, Minari R, Viani I, Tassi F, Bonatti F, Neri TM, Bertolini L, Bernasconi S, Ghizzoni L.
|
| J Clin Endocrinol Metab 96(12):E1953-62. doi: 10.1210/jc.2011-0511. Epub 2011 Sep 21.
2011
|
| 43 | AR, NCOA3
|
| Identification of SRC3/AIB1 as a preferred coactivator for hormone-activated androgen receptor.
|
| Zhou XE, Suino-Powell KM, Li J, He Y, Mackeigan JP, Melcher K, Yong EL, Xu HE.
|
| J Biol Chem 285(12):9161-71. Epub 2010 Jan 19.PMID: 20086010 2010
|
| 44 | AR, ZNF652
|
| Co-expression of the androgen receptor and the transcription factor ZNF652 is related to prostate cancer outcome.
|
| Callen DF, Ricciardelli C, Butler M, Stapleton A, Stahl J, Kench JG, Horsfall DJ, Tilley WD, Schulz R, Nesland JM, Neilsen PM, Kumar R, Holm R.
|
| Oncol Rep 23(4):1045-52.
2010
|
| 45 | AR, CDK9
|
| CDK9 regulates AR promoter selectivity and cell growth through serine 81 phosphorylation.
|
| Gordon V, Bhadel S, Wunderlich W, Zhang J, Ficarro SB, Mollah SA, Shabanowitz J, Hunt DF, Xenarios I, Hahn WC, Conaway M, Carey MF, Gioeli D.
|
| Mol Endocrinol 24(12):2267-80. doi: 10.1210/me.2010-0238. Epub 2010 Oct 27.
2010
|
| 46 | AR
|
| Phosphorylation and activation of androgen receptor by Aurora-A.
|
| Shu SK, Liu Q, Coppola D, Cheng JQ.
|
| J Biol Chem 285(43):33045-53. doi: 10.1074/jbc.M110.121129. Epub 2010 Aug 16.
2010
|
| 47 | AR, EP300, MAGEA11
|
| Transcriptional synergy between melanoma antigen gene protein-A11 (MAGE-11) and p300 in androgen receptor signaling.
|
| Askew EB, Bai S, Blackwelder AJ, Wilson EM.
|
| J Biol Chem 285(28):21824-36. doi: 10.1074/jbc.M110.120600. Epub 2010 May 6.
2010
|
| 48 | AR, SBMA
|
| Mitochondrial abnormalities in spinal and bulbar muscular atrophy.
|
| Ranganathan S, Harmison GG, Meyertholen K, Pennuto M, Burnett BG, Fischbeck KH.
|
| Hum Mol Genet 18(1):27-42. Epub 2008 Sep 29.
2009
|
| 49 | AR
|
| Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy.
|
| Abbas S, Brauch H, Chang-Claude J, Dünnebier T, Flesch-Janys D, Hamann U, Hein R, Justenhoven C, Salazar R.
|
| Int J Cancer nt J Cancer. 2009 Sep 8. [Epub ahead of print]PMID: 19739075 2009
|
| 50 | AR
|
| Longer CAG repeat length in the androgen receptor gene is associated with premature ovarian failure.
|
| Chatterjee S, Singh R, Kadam S, Maitra A, Thangaraj K, Meherji P, Modi D.
|
| Hum Reprod 24(12):3230-5. Epub 2009 Aug 14.PMID: 19684044 2009
|
| 51 | AR, HSPB1, PRKD1
|
| Heat shock protein 27 mediates repression of androgen receptor function by protein kinase D1 in prostate cancer cells.
|
| Hassan S, Biswas MH, Zhang C, Du C, Balaji KC.
|
| Oncogene 28(49):4386-96. Epub .PMID: 19767773 2009
|
| 52 | AR, RAN
|
| ARA24/Ran enhances the androgen-dependent NH2- and COOH-terminal interaction of the androgen receptor.
|
| Harada N, Ohmori Y, Yamaji R, Higashimura Y, Okamoto K, Isohashi F, Nakano Y, Inui H.
|
| Biochem Biophys Res Commun 373(3):373-7. Epub 2008 Jun 17.
2008
|
| 53 | RANBP10, AR
|
| RanBP10 acts as a novel coactivator for the androgen receptor.
|
| Harada N, Yokoyama T, Yamaji R, Nakano Y, Inui H.
|
| Biochem Biophys Res Commun 368(1):121-5. Epub 2008 Jan 24. 2008
|
| 54 | AR
|
| Association of androgen receptor CAG repeat polymorphism and polycystic ovary syndrome.
|
| Shah NA, Antoine HJ, Pall M, Taylor KD, Azziz R, Goodarzi MO.
|
| J Clin Endocrinol Metab 93(5):1939-45. Epub 2008 Feb 26. 2008
|
| 55 | AR, DAPK3
|
| ZIP kinase plays a crucial role in androgen receptor-mediated transcription.
|
| Leister P, Felten A, Chasan AI, Scheidtmann KH.
|
| Oncogene 27(23):3292-300. Epub 2007 Dec 17. 2008
|
| 56 | AR
|
| Androgen receptor is a tumor suppressor and proliferator in prostate cancer.
|
| Niu Y, Altuwaijri S, Lai KP, Wu CT, Ricke WA, Messing EM, Yao J, Yeh S, Chang C.
|
| Proc Natl Acad Sci U S A 105(34):12182-7. Epub 2008 Aug 22.
2008
|
| 57 | AR, SBMA
|
| CAG repeat size correlates to electrophysiological motor and sensory phenotypes in SBMA.
|
| Suzuki K, Katsuno M, Banno H, Takeuchi Y, Atsuta N, Ito M, Watanabe H, Yamashita F, Hori N, Nakamura T, Hirayama M, Tanaka F, Sobue G.
|
| Brain 131(Pt 1):229-39. Epub 2007 Dec 4.PMID: 18056738 2008
|
| 58 | AR, PMEPA1
|
| A feedback loop between the androgen receptor and a NEDD4-binding protein, PMEPA1, in prostate cancer cells.
|
| Li H, Xu LL, Masuda K, Raymundo E, McLeod DG, Dobi A, Srivastava S.
|
| J Biol Chem 283(43):28988-95. Epub 2008 Aug 14.
2008
|
| 59 | AIS, AR
|
| A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation.
|
| Wong HY, Hoogerbrugge JW, Pang KL, van Leeuwen M, van Royen ME, Molier M, Berrevoets CA, Dooijes D, Dubbink HJ, van de Wijngaart DJ, Wolffenbuttel KP, Trapman J, Kleijer WJ, Drop SL, Grootegoed JA, Brinkmann AO.
|
| Mol Cell Endocrinol 292(1-2):69-78. Epub 2008 Jul 5.
2008
|
| 60 | AR, TAGLN, RNF14
|
| Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth.
|
| Yang Z, Chang YJ, Miyamoto H, Ni J, Niu Y, Chen Z, Chen YL, Yao JL, di Sant'Agnese PA, Chang C.
|
| Mol Endocrinol 21(2):343-58. Epub 2006 Nov 2. 2007
|
| 61 | AR, FOXG1
|
| FoxG1, a member of the forkhead family, is a corepressor of the androgen receptor.
|
| Obendorf M, Meyer R, Henning K, Mitev YA, Schröder J, Patchev VK, Wolf SS.
|
| J Steroid Biochem Mol Biol 104(3-5):195-207. Epub 2007 Mar 23.
2007
|
| 62 | AR
|
| Male infertility and variation in CAG repeat length in the androgen receptor gene: a meta-analysis.
|
| Davis-Dao CA, Tuazon ED, Sokol RZ, Cortessis VK.
|
| J Clin Endocrinol Metab 92(11):4319-26. Epub 2007 Aug 7.PMID: 17684052 2007
|
| 63 | AR, AIS
|
| Impaired helix 12 dynamics due to proline 892 substitutions in the androgen receptor are associated with complete androgen insensitivity.
|
| Elhaji YA, Stoica I, Dennis S, Purisima EO, Lumbroso R, Beitel LK, Trifiro MA.
|
| Hum Mol Genet 15(9):1561. No abstract available. 2006
|
| 64 | HAP1, AR
|
| Huntingtin-associated protein 1 (HAP1) interacts with androgen receptor (AR) and suppresses SBMA-mutant-AR-induced apoptosis.
|
| Takeshita Y, Fujinaga R, Zhao C, Yanai A, Shinoda K.
|
| Hum Mol Genet 15(15):2298-312. Epub 2006 Jun 16. 2006
|
| 65 | SCA1, ATXN1, SCA2, ATXN2, MJD, ATXN3, SCA6, CACNA1A, SCA7, ATXN7, SCA17, TBP, DRPLA, ATN1, SBMA, AR
|
| Transcriptional alterations and chromatin remodeling in polyglutamine diseases.
|
| Helmlinger D, Tora L, Devys D.
|
| Trends Genet 22(10):562-70. Epub 2006 Sep 5. 2006
|
| 66 | AR, AIS
|
| Human androgen receptor gene ligand-binding-domain mutations leading to disrupted interaction between the N- and C-terminal domains.
|
| Jskelinen J, Deeb A, Schwabe JW, Mongan NP, Martin H, Hughes IA.
|
| J Mol Endocrinol 36(2):361-8. 2006
|
| 67 | SBMA, AR
|
| Natural history of spinal and bulbar muscular atrophy (SBMA): a study of 223 Japanese patients.
|
| Atsuta N, Watanabe H, Ito M, Banno H, Suzuki K, Katsuno M, Tanaka F, Tamakoshi A, Sobue G.
|
| Brain 129(Pt 6):1446-55. Epub 2006 Apr 18. 2006
|
| 68 | AR, CFLAR, PAWR
|
| Androgen receptor and prostate apoptosis response factor-4 target the c-FLIP gene to determine survival and apoptosis in the prostate gland.
|
| Gao S, Wang H, Lee P, Melamed J, Li CX, Zhang F, Wu H, Zhou L, Wang Z.
|
| J Mol Endocrinol 36(3):463-83. 2006
|
| 69 | AR
|
| Mutation of the androgen receptor causes oncogenic transformation of the prostate.
|
| Han G, Buchanan G, Ittmann M, Harris JM, Yu X, Demayo FJ, Tilley W, Greenberg NM.
|
| Proc Natl Acad Sci U S A 102(4):1151-6. Epub 2005 Jan 18. 2005
|
| 70 | FOXO3, AR
|
| Induction of androgen receptor expression by phosphatidylinositol 3-kinase/Akt downstream substrate, FOXO3a, and their roles in apoptosis of LNCaP prostate cancer cells.
|
| Yang L, Xie S, Jamaluddin MS, Altuwaijri S, Ni J, Kim E, Chen YT, Hu YC, Wang L, Chuang KH, Wu CT, Chang C.
|
| J Biol Chem 280(39):33558-65. Epub 2005 Aug 1. 2005
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| 71 | FXN, FRDA, FRAXA, FMR1, FRAXE, ATXN1, SCA1, ATXN2, SCA2, ATXN3, MJD, ATXN7, SCA7, SCA6, CACNA1A, SCA17, TBP, DRPLA, ATN1, AR, SBMA, DM1, DMPK, DM2, CNBP, SCA10, ATXN10, SCA12, PPP2R2B, SCA8, ATXN8OS
|
| Diseases of unstable repeat expansion: mechanisms and common principles.
|
| Gatchel JR, Zoghbi HY.
|
| Nat Rev Genet 6(10):743-55. Review. 2005
|
| 72 | SMARCE1, AR
|
| BAF57 governs androgen receptor action and androgen-dependent proliferation through SWI/SNF.
|
| Link KA, Burd CJ, Williams E, Marshall T, Rosson G, Henry E, Weissman B, Knudsen KE.
|
| Mol Cell Biol 25(6):2200-15. 2005
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| 73 | AR,RNASEL
|
| Interaction between the androgen receptor and RNase L mediates a cross-talk between the interferon and androgen signaling pathways.
|
| Bettoun DJ, Scafonas A, Rutledge SJ, Hodor P, Chen O, Gambone C, Vogel R, McElwee-Witmer S, Bai C, Freedman L, Schmidt A.
|
| J Biol Chem 280(47):38898-901. Epub 2005 Sep 14. 2005
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| 74 | AR, AIS
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| Molecular features and clinical phenotypes in androgen insensitivity syndrome in the absence and presence of androgen receptor gene mutations.
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| Holterhus PM, Werner R, Hoppe U, Bassler J, Korsch E, Ranke MB, Dorr HG, Hiort O.
|
| J Mol Med 83(12):1005-13. Epub 2005 Nov 11. 2005
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| 75 | USP10, AR
|
| The ubiquitin-specific protease USP10 modulates androgen receptor function.
|
| Faus H, Meyer HA, Huber M, Bahr I, Haendler B.
|
| Mol Cell Endocrinol 245(1-2):138-46. Epub 2005 Dec 20. 2005
|
| 76 | AGA, AGA2, AGA3, AR
|
| Genetic variation in the human androgen receptor gene is the major determinant of common early-onset androgenetic alopecia.
|
| Hillmer AM, Hanneken S, Ritzmann S, Becker T, Freudenberg J, Brockschmidt FF, Flaquer A, Freudenberg-Hua Y, Jamra RA, Metzen C, Heyn U, Schweiger N, Betz RC, Blaumeiser B, Hampe J, Schreiber S, Schulze TG, Hennies HC, Schumacher J, Propping P, Ruzicka T, Cichon S, Wienker TF, Kruse R, Nothen MM.
|
| Am J Hum Genet 77(1):140-8. Epub 2005 May 18. 2005
|
| 77 | WT1, SRD5A2, AR, PPSH
|
| Mutation analysis of five candidate genes in Chinese patients with hypospadias.
|
| Wang Y, Li Q, Xu J, Liu Q, Wang W, Lin Y, Ma F, Chen T, Li S, Shen Y.
|
| Eur J Hum Genet 12(9):706-12. 2004
|
| 78 | LATS2, AR
|
| The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.
|
| Powzaniuk M, McElwee-Witmer S, Vogel RL, Hayami T, Rutledge SJ, Chen F, Harada S, Schmidt A, Rodan GA, Freedman LP, Bai C.
|
| Mol Endocrinol 18(8):2011-23. Epub 2004 May 6. 2004
|
| 79 | AR
|
| CAG repeat length in androgen-receptor gene and reproductive variables in fertile and infertile men.
|
| Rajpert-De Meyts E, Leffers H, Petersen JH, Andersen AG, Carlsen E, Jorgensen N, Skakkebaek NE.
|
| Lancet 359(9300):44-6. 2002
|
| 80 | AR
|
| Polymorphic GGC repeats in the androgen receptor gene are associated with hereditary and sporadic prostate cancer risk.
|
| Chang Bl BL, Zheng SL, Hawkins GA, Isaacs SD, Wiley KE, Turner A, Carpten JD, Bleecker ER, Walsh PC, Trent JM, Meyers DA, Isaacs WB, Xu J.
|
| Hum Genet 110(2):122-9. 2002
|
| 81 | UXT, AR
|
| Identification and characterization of ART-27, a novel coactivator for the androgen receptor N terminus.
|
| Markus SM, Taneja SS, Logan SK, Li W, Ha S, Hittelman AB, Rogatsky I, Garabedian MJ.
|
| Mol Biol Cell 13(2):670-82. 2002
|
| 82 | AR, RCHY1
|
| Cloning and characterization of an androgen receptor N-terminal-interacting protein with ubiquitin-protein ligase activity.
|
| Beitel LK, Elhaji YA, Lumbroso R, Wing SS, Panet-Raymond V, Gottlieb B, Pinsky L, Trifiro MA.
|
| J Mol Endocrinol 29(1):41-60. 2002
|
| 83 | SVIL, AR
|
| Supervillin associates with androgen receptor and modulates its transcriptional activity.
|
| Ting HJ, Yeh S, Nishimura K, Chang C.
|
| Proc Natl Acad Sci U S A 99(2):661-6. Epub 2002 Jan 15. 2002
|
| 84 | AR, SMAD3
|
| From transforming growth factor-beta signaling to androgen action: Identification of Smad3 as an androgen receptor coregulator in prostate cancer cells.
|
| Kang HY, Lin HK, Hu YC, Yeh S, Huang KE, Chang C.
|
| Proc Natl Acad Sci U S A 98(6):3018-3023. 2001
|
| 85 | AR
|
| Participation of critical residues from the extreme C-terminal end of the human androgen receptor in the ligand binding function.
|
| Tahiri B, Auzou G, Nicolas JC, Sultan C, Lupo B.
|
| Biochemistry 40(29):8431-7. 2001
|
| 86 | AR, AIS
|
| Eight novel mutations of the androgen receptor gene in patients with androgen insensitivity syndrome.
|
| Chavez B, Mendez JP, Ulloa-Aguirre A, Larrea F, Vilchis F.
|
| J Hum Genet 46(10):560-5. 2001
|
| 87 | AR
|
| SMAD3 represses androgen receptor-mediated transcription.
|
| Hayes SA, Zarnegar M, Sharma M, Yang F, Peehl DM, ten Dijke P, Sun Z.
|
| Cancer Res 61(5):2112-8. 2001
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| 88 | AR
|
| The androgen receptor (AR) amino-terminus imposes androgen-specific regulation of AR gene expression via an exonic enhancer.
|
| Grad JM, Lyons LS, Robins DM, Burnstein KL.
|
| Endocrinology 142(3):1107-16. 2001
|
| 89 | AR, SBMA
|
| Motoneuronal cell death is not correlated with aggregate formation of androgen receptors containing an elongated polyglutamine tract.
|
| Simeoni S, Mancini MA, Stenoien DL, Marcelli M, Weigel NL, Zanisi M, Martini L, Poletti A.
|
| Hum Mol Genet 9(1):133-44 2000
|
| 90 | AR, AIS
|
| Longer polyglutamine tracts in the androgen receptor are associated with moderate to severe undermasculinized genitalia in XY males.
|
| Lim HN, Chen H, McBride S, Dunning AM, Nixon RM, Hughes IA, Hawkins JR.
|
| Hum Mol Genet 9(5):829-34. 2000
|
| 91 | AR
|
| The expansion of the CAG repeat in exon 1 of the human androgen receptor gene is associated with uterine endometrial carcinoma.
|
| Sasaki M, Dahiya R, Fujimoto S, Ishikawa M, Oshimura M.
|
| Mol Carcinog 27(3):237-44. 2000
|
| 92 | AR
|
| Androgen receptor mRNA expression in the human hippocampus.
|
| Beyenburg S, Watzka M, Clusmann H, Blumcke I, Bidlingmaier F, Elger CE, Stoffel-Wagner B.
|
| Neurosci Lett 294(1):25-8. 2000
|
| 93 | AR
|
| Glucocorticoids can promote androgen-independent growth of prostate cancer cells through a mutated androgen receptor.
|
| Zhao XY, Malloy PJ, Krishnan AV, Swami S, Navone NM, Peehl DM, Feldman D.
|
| Nat Med 6(6):703-6. 2000
|
| 94 | AR, SBMA
|
| Kennedy's disease : caspase cleavage of the androgen receptor is a crucial event in cytotoxicity.
|
| Ellerby LM, et al.
|
| J Neurochem 72 : 185-195. 1999
|
| 95 | AR, AIS
|
| CAG repeat length in the androgen receptor gene of infertile Japanese males with oligozoospermia.
|
| Komori S, et al.
|
| Mol Hum Reprod 5(1):14-6. 1999
|
| 96 | AR
|
| (CAG)nCAA and GGN repeats in the human androgen receptor gene are not associated with prostate cancer in a French-German population.
|
| Correa-Cerro L, et al.
|
| Eur J Hum Genet 7(3):357-62. 1999
|
| 97 | AR, SBMA
|
| Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone.
|
| Stenoien DL, et al.
|
| Hum Mol Genet 8(5):731-41. 1999
|
| 98 | AR, AIS
|
| Update of the androgen receptor gene mutations database.
|
| Gottlieb B, et al.
|
| Hum Mutat 14(2):103-14. 1999
|
| 99 | AR, AIS
|
| Complete androgen insensitivity caused by a splice donor site mutation in intron 2 of the human androgen receptor gene resulting in an exon 2-lacking transcript with premature stop-codon and reduced expression.
|
| Hellwinkel OJ, et al.
|
| J Steroid Biochem Mol Biol 68(1-2):1-9. 1999
|
| 100 | AR, AIS
|
| Complete androgen insensitivity caused by a new frameshift deletion of two base pairs in exon 1 of the human androgen receptor gene.
|
| Thiele B, et al.
|
| J Clin Endocrinol Metab 84(5):1751-3. 1999
|
| 101 | AR, AIS
|
| Linkage between male infertility and trinucleotide repeat expansion in the androgen-receptor gene.
|
| Dowsing AT, et al.
|
| Lancet 354(9179):640-3. 1999
|
| 102 | AR, SBMA
|
| Tissue-Specific Somatic Mosaicism in Spinal and Bulbar Muscular Atrophy Is Dependent on CAG-Repeat Length and Androgen Receptor-Gene Expression Level.
|
| Tanaka F, et al.
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| Am J Hum Genet 65(4):966-973 1999
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| 103 | ABCB7, AR, ARR3, FOXO4, OGT, RPS4X, VDAC1P
|
| Transcript map of the human chromosome Xq11-Xq21 region: localization of 33 novel genes and one pseudogene.
|
| Villard L, Belougne J, Lossi AM, Fontes M, Colleaux L.
|
| Gene 235(1-2):43-50 1999
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| 104 | AR
|
| A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1).
|
| Nazareth LV, Stenoien DL, Bingman WE 3rd, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL.
|
| Mol Endocrinol 13(12):2065-75. 1999
|
| 105 | AR, SBMA
|
| Truncated forms of the androgen receptor are associated with polyglutamine expansion in X-linked spinal and bulbar muscular atrophy.
|
| Butler R, Leigh PN, McPhaul MJ, Gallo JM.
|
| Hum Mol Genet 7(1):121-7. 1998
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| 106 | AR, SBMA
|
| Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy.
|
| Merry DE, et al.
|
| Hum Mol Genet 7 : 693-701. 1998
|
| 107 | AR
|
| Analysis of the transactivation domain of the androgen receptor in patients with male infertility.
|
| Wang Q, et al.
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| Clin Genet 54 : 185-192. 1998
|
| 108 | AR, CASP3, SBMA
|
| Caspase-3 cleaves the expanded androgen receptor protein of spinal and bulbar muscular atrophy in a polyglutamine repeat length-dependent manner.
|
| Kobayashi Y, Miwa S, Merry DE, Kume A, Mei L, Doyu M, Sobue G.
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| Biochem Biophys Res Commun 252(1):145-50. 1998
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| 109 | AR
|
| Azoospermia associated with a mutation in the ligand-binding domain of an androgen receptor displaying normal ligand binding, but defective trans-activation.
|
| Wang Q, et al.
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| J Clin Endocrinol Metab 83 : 4303-4309. 1998
|
| 110 | ADRBK1, AR, ZFHX3, CACNA1A, CAPNS1, FOXE1, FOXF1, FMR1, AFF2, HCN1, NRXN1, CA10
|
| CCG repeats in cDNAs from human brain.
|
| Kleiderlein JJ, Nisson PE, Jessee J, Li WB, Becker KG, Derby ML, Ross CA, Margolis RL.
|
| Hum Genet 103(6):666-73. 1998
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| 111 | AR
|
| Mutations of the androgen receptor gene in patients with complete androgen insensitivity.
|
| Jakubiczka S, et al.
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| Hum Mutat 9 : 57-61. 1997
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| 112 | AR
|
| The CAG repeat within the androgen receptor gene and its relationship to prostate cancer.
|
| Giovannucci E, et al.
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| Proc Natl Acad Sci U S A 94 : 3320-3323. 1997
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| 113 | AR
|
| Altered mRNA expression due to insertion or substitution of thymine at position +3 of two splice-donor sites in the androgen receptor gene.
|
| Trifiro MA, Lumbroso R, Beitel LK, Vasiliou DM, Bouchard J, Deal C, Van Vliet G, Pinsky L.
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| Eur J Hum Genet 5(1):50-8. 1997
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| 114 | AR
|
| Mutation and microsatellite instability analysis of the androgen receptor gene in human prostate cancer.
|
| Uchida T, et al.
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| Int J Oncol 11 : 551-556. 1997
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| 115 | AR
|
| Molecular analysis of the androgen-receptor gene in a family with receptor-positive partial androgen insensitivity : an unusual type of intronic mutation.
|
| Bruggenwirth HT, Boehmer AL, Ramnarain S, Verleun-Mooijman MC, Satijn DP, Trapman J, Grootegoed JA, Brinkmann AO.
|
| Am J Hum Genet 61(5):1067-77. 1997
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| 116 | AR
|
| Functional analysis of six androgen receptor mutations identified in patients with partial androgen insensitivity syndrome.
|
| Bevan CL, et al.
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| Hum Mol Genet 5 : 265-273. 1996
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| 117 | AR, SBMA
|
| CAG-repeat expansion in androgen receptor in Kennedy's disease is not a loss of function mutation.
|
| Neuschmid-Kaspar F, et al.
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| Mol Cell Endocrinol 117 : 149-156. 1996
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| 118 | AR
|
| Short report on DNA marker at candidate locus. A Stu I polymorphism in the human androgen receptor gene (AR).
|
| Lu J, et al.
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| Clin Genet 49 : 323-324. 1996
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| 119 | AR
|
| Different phenotypes in a family with androgen insensitivity caused by the same M780I point mutation in the androgen receptor gene.
|
| Rodien P, et al.
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| J Clin Endocrinol Metab 81 : 2994-2998. 1996
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| 120 | AR
|
| A novel missense mutation in the amino-terminal domain of the human androgen receptor gene in a family with partial androgen insensitivity syndrome causes reduced efficiency of protein translation.
|
| Choong CS, et al.
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| J Clin Invest 98 : 1423-1431. 1996
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| 121 | AR
|
| Complete androgen insensitivity syndrome due to a new frameshift deletion in exon 4 of the androgen receptor gene : functional analysis of the mutant receptor.
|
| Lobaccaro JM, et al.
|
| Mol Cell Endocrinol 111 : 21-28. 1995
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| 122 | AR
|
| Characterization of alternative amino acid substitutions at arginine 830 of the androgen receptor that cause complete androgen insensitivity in three families.
|
| Shkolny DL, et al.
|
| Hum Mol Genet 4 : 515-521. 1995
|
| 123 | AR
|
| Mutation of the androgen-receptor gene in metastatic androgen-independent prostate cancer.
|
| Taplin ME, et al.
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| N Engl J Med 332 : 1393-1398. 1995
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| 124 | AR, ATXN3, ATXN1
|
| Sequence variation and size ranges of CAG repeats in the Machado-Joseph disease, spinocerebellar ataxia type 1 and androgen receptor genes.
|
| Rubinsztein DC, et al.
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| Hum Mol Genet 4 : 1585-1590. 1995
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| 125 | AR
|
| Human androgen insensitivity due to point mutations encoding amino acid substitutions in the androgen receptor steroid-binding domain.
|
| Murono K, et al.
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| Hum Mutat 6 : 152-162. 1995
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| 126 | AR
|
| Leu-676-Pro mutation of the androgen receptor causes complete androgen insensitivity syndrome in a large hutterite kindred.
|
| Belsham DD, et al.
|
| Hum Mutat 5 : 28-33. 1995
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| 127 | AR
|
| Complete androgen insensitivity due to mutations in the probable alpha-helical segments of the DNA-binding domain in the human androgen receptor.
|
| Beitel LK, et al.
|
| Hum Mol Genet 3 : 21-27. 1994
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| 128 | AR
|
| Microsatellite mutation (CAG24-18) in the androgen receptor gene in human prostate cancer.
|
| Schoenberg MP, et al.
|
| Biochem Biophys Res Commun 198 : 74-80. 1994
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| 129 | AR
|
| Differential splicing of human androgen receptor Pre-mRNA in X-linked Reifenstein syndrome, because of a deletion involving a putative branch site.
|
| Ris-Stalpers C, et al.
|
| Am J Hum Genet 54 : 609-617. 1994
|
| 130 | AR
|
| Two mutations causing complete androgen insensitivity : a frame-shift in the steroid binding domain and a Cys-Phe substitution in the second zinc finger of the androgen receptor.
|
| Baldazzi L, et al.
|
| Hum Mol Genet 3 : 1169-1170. 1994
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| 131 | AR
|
| Detection of point mutations in the androgen receptor gene using non-isotopic single strand conformation polymorphism analysis.
|
| Hiort O, et al.
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| Hum Mol Genet 3 : 1163-1166. 1994
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| 132 | AR
|
| Substitution of arginine-839 by cysteine or histidine in the androgen receptor causes different receptor phenotypes in cultured cells and coordinate degrees of clinical androgen resistance.
|
| Beitel LK, et al.
|
| J Clin Invest 94 : 546-554. 1994
|
| 133 | AR
|
| Characterization of mutant androgen receptors causing partial androgen insensitivity syndrome.
|
| De Bellis A, et al.
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| J Clin Endocrinol Metab 78 : 513-522. 1994
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| 134 | AR, AIS
|
| A practical approach to the detection of androgen receptor gene mutations and pedigree analysis in families with X-linked androgen insensitivity.
|
| Ris-Stalpers C, et al.
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| Pediatr Res 36 : 227-234. 1994
|
| 135 | AR, SBMA
|
| Androgen receptor mRNA with increased size of tandem CAG repeat is widely expressed in the neural and nonneural tissues of X-linked recessive bulbospinal neuronopathy.
|
| Doyu M, et al.
|
| J Neurol Sci 127 : 43-47. 1994
|
| 136 | AR
|
| Related individuals with different androgen receptor gene deletions.
|
| MacLean HE, et al.
|
| J Clin Invest 91 : 1123-1128. 1993
|
| 137 | AR, AIS
|
| Complete testicular feminization caused by an amino-terminal truncation of the androgen receptor with downstream initiation.
|
| Zoppi S, et al.
|
| J Clin Invest 91 : 1105-1112. 1993
|
| 138 | AR
|
| Androgen receptor gene mutation in male breast cancer.
|
| Lobaccaro JM, et al.
|
| Hum Mol Genet 2 : 1799-1802. 1993
|
| 139 | AR
|
| A single-base substitution in exon 6 of the androgen receptor gene causing complete androgen insensitivity : the mutated receptor fails to transactivate but binds to DNA in vitro.
|
| Adeyemo O, et al.
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| Hum Mol Genet 2 : 1809-1812. 1993
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| 140 | AR
|
| Trinucleotide (GGN) repeat polymorphism in the human androgen receptor (AR) gene.
|
| Sleddens HFBM, et al.
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| Hum Mol Genet 2 : 493. 1993
|
| 141 | AR
|
| An exonic point mutation creates a MaeIII site in the androgen receptor gene of a family with complete androgen insensitivity syndrome.
|
| Lobaccaro JM, et al.
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| Hum Mol Genet 2 : 1041-1043. 1993
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| 142 | AR, HTT, DM1, FMR1
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| Fragile X syndrome unstable element, p(CCG)n, and other simple tandem repeat sequences are binding sites for specific nuclear proteins.
|
| Richards RI, et al.
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| Hum Mol Genet 2 : 1429-1435. 1993
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| 143 | AR
|
| A point mutation in the second zinc finger of the DNA-binding domain of the androgen receptor gene causes complete androgen insensitivity in two siblings with receptor-positive androgen resistance.
|
| Mowszowicz I, et al.
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| Mol Endocrinol 7 : 861-869. 1993
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| 144 | AR
|
| Sequence variation in the androgen receptor gene is not a common determinant of male sexual orientation.
|
| Macke JP, et al.
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| Am J Hum Genet 53 : 844-852. 1993
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| 145 | AR, SBMA
|
| Reduced transcriptional regulatory competence of the androgen receptor in X-linked spinal and bulbar muscular atrophy.
|
| Mhatre AN, et al.
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| Nat Genet 5 : 184-187. 1993
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| 146 | AR
|
| Trinucleotide repeat polymorphism in the androgen receptor gene (AR).
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| Sleddens HFBM, et al.
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| Nucleic Acids Res 20 : 1427. 1992
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| 147 | AR
|
| Point mutation in the DNA binding domain of the androgen receptor in two families with Reifenstein syndrome.
|
| Klocker H, et al.
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| Am J Hum Genet 50 : 1318-1327. 1992
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| 148 | AR
|
| Replacement of arginine 773 by cysteine or histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes.
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| Prior L, et al.
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| Am J Hum Genet 51 : 143-155. 1992
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| 149 | AR, AIS
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| Androgen receptor gene mutations identified by SSCP in fourteen subjects with androgen insensitivity syndrome.
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| Batch JA, et al.
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| Hum Mol Genet 1 : 497-503. 1992
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| 150 | AR
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| A germline mutation in the androgen receptor gene in two brothers with breast cancer and Reifenstein syndrome.
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| Wooster R, et al.
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| Nat Genet 2 : 132-134. 1992
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| 151 | AR
|
| Mutations in the ligand-binding domain of the androgen receptor gene cluster in two regions of the gene.
|
| McPhaul MJ, et al.
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| J Clin Invest 90 : 2097-2101. 1992
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| 152 | AR
|
| Point mutation in the steroid-binding domain of the androgen receptor gene in a family with complete androgen insensitivity syndrome (CAIS).
|
| Jakubiczka S, et al.
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| Hum Genet 90 : 311-312. 1992
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| 153 | AR, AIS
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| Complete deletion of the androgen receptor gene : definition of the null phenotype of the androgen insensitivity syndrome and determination of carrier status.
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| Quigley CA, et al.
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| J Clin Endocrinol Metab 74 : 927-933. 1992
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| 154 | SBMA, AR
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| X-linked spinomuscular atrophy; a kindred with associated abnormal androgen receptor binding.
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| Warner CL, et al.
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| Neurology 42 : 2181-2184. 1992
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| 155 | AR
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| Single base mutations in the human androgen receptor gene causing complete androgen insensitivity : rapid detection by a modified denaturing gradient gel electrophoresis technique.
|
| De Bellis A, et al.
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| Mol Endocrinol 6 : 1909-1920. 1992
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| 156 | FABP2, AR, TH, REN, HPRT1
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| Genetic variation at five trimeric and tetrameric tandem repeat loci in four human population groups.
|
| Edwards A, et al.
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| Genomics 12 : 241-253. 1992
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| 157 | AR
|
| Methylation of Hpall and Hhal sites near the polymorphic CAG repeat in the human androgen-receptor gene correlates with X chromosome inactivation.
|
| Allen RC, et al.
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| Am J Hum Genet 51 : 1229-1239. 1992
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| 158 | AR, AIS
|
| Association of the Hind III polymorphism with the androgen receptor gene in partial androgen insensitivity syndrome.
|
| Lobaccaro JM, et al.
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| Ann Genet 34 : 9-13. 1991
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| 159 | AR
|
| Androgen resistance associated with a mutation of the androgen receptor at amino acid 772 (Arg-Cys) results from a combination of decreased messenger ribonucleic acid levels and impairment of receptor function.
|
| Marcelli M, et al.
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| J Clin Endocrinol Metab 73 : 318-325. 1991
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| 160 | AR
|
| Amber mutation creates a diagnostic MaeI site in the androgen receptor gene of a family with complete androgen insensitivity.
|
| Trifiro M, et al.
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| Am J Med Genet 40 : 493-499. 1991
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| 161 | AR, AIS
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| Evidence for a partial deletion in the androgen receptor gene in a phenotypic male with azoospermia.
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| Akin JW, et al.
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| Am J Obstet Gynecol 165 : 1891-1894. 1991
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| 162 | AR
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| A mutation in the DNA-binding domain of the androgen receptor gene causes complete testicular feminization in a patient with receptor-positive androgen resistance.
|
| Marcelli M, et al.
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| J Clin Invest 87 : 1123-1126. 1991
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| 163 | AR
|
| Molecular basis of androgen resistance in a family with a qualitative abnormality of the androgen receptor and responsive to high-dose androgen therapy.
|
| McPhaul MJ, et al.
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| J Clin Invest 87 : 1413-1421. 1991
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| 164 | AR, AIS
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| DNA linkage analysis and studies of the androgen receptor gene in a large kindred with complete androgen insensitivity.
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| Imperato-McGinley J, et al.
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| Am J Med Genet 36 : 104-108. 1990
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| 165 | AR, AIS
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| Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgen resistance: premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance.
|
| Marcelli M, et al.
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| Mol Endocrinol 4 : 1105-1116. 1990
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| 166 | AR, AIS
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| An exonic point mutation of the androgen receptor gene in a family with complete androgen insensitivity.
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| Sai T, et al.
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| Am J Hum Genet 46 : 1095-1100. 1990
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| 167 | AR
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| Functional characterization of naturally occurring mutant androgen receptors from subjects with complete androgen insensitivity.
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| Brown TR, et al.
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| Mol Endocrinol 4 : 1759-1772. 1990
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| 168 | AR
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| Androgen-selective androgen resistance due to a single amino acid substitution in the androgen-binding domain of the X-linked androgen receptor.
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| Mhatre A, et al.
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| Am J Hum Genet 47 : A115. 1990
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| 169 | AR, AIS
|
| Aberrant splicing of androgen receptor mRNA results in synthesis of a nonfunctional receptor protein in a patient with androgen insensitivity.
|
| Ris-Stalpers C, et al.
|
| Proc Natl Acad Sci U S A 87 : 7866-7870. 1990
|
| 170 | AR
|
| Expression of the human androgen receptor gene utilizes a common promoter in diverse human tissues and cell lines.
|
| Tilley WD, Marcelli M, McPhaul MJ.
|
| J Biol Chem 265(23):13776-81. 1990
|
| 171 | AR
|
| Androgen receptor locus on the human X chromosome: regional localization to Xq11-12 and description of a DNA polymorphism.
|
| Brown CJ, et al.
|
| Am J Hum Genet 44 : 264-269. 1989
|
| 172 | AR, AIS
|
| Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.
|
| Lubahn DB, et al.
|
| Proc Natl Acad Sci U S A 86 : 9534-9538. 1989
|
| 173 | AR, AIS
|
| Deletion of the steroid-binding domain of the human androgen receptor gene in one family with complete androgen insensitivity syndrome: Evidence for further genetic heterogeneity in this syndrome.
|
| Brown TR, et al.
|
| Proc Natl Acad Sci U S A 85 : 8151-8155. 1988
|
| 174 | AR
|
| Cloning of human androgen receptor complementary DNA and localization to the X chromosome.
|
| Lubahn DB, et al.
|
| Science 240 : 327-330. 1988
|
| 175 | AR, DXS1, AIS
|
| Genetic linkage of testicular feminization syndrome to DXS1 and PGK1.
|
| Balazs I, et al.
|
| Am J Hum Genet 43 : A136. 1988
|
| 176 | AR
|
| Cloning, structure and expression of a cDNA encoding the human androgen receptor.
|
| Trapman J, Klaassen P, Kuiper GG, van der Korput JA, Faber PW, van Rooij HC, Geurts van Kessel A, Voorhorst MM, Mulder E, Brinkmann AO.
|
| Biochem Biophys Res Commun 153(1):241-8. 1988
|
| 177 | AR
|
| The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate.
|
| Lubahn DB, Joseph DR, Sar M, Tan J, Higgs HN, Larson RE, French FS, Wilson EM.
|
| Mol Endocrinol 2(12):1265-75. 1988
|
| 178 | AR, DXS1, AIS
|
| Linkage analysis with RFLPs in families with androgen resistance syndromes : evidence for close linkage between the androgen receptor locus and DXS1 segment.
|
| Wieacker P, et al.
|
| Hum Genet 76 : 248-252. 1987
|
| 179 | AR
|
| Studies of the locus for androgen receptor: localization on the human X chromosome and evidence for homology with the Tfm locus in the mouse.
|
| Migeon BR, et al.
|
| Proc Natl Acad Sci U S A 78 : 6339-6343. 1981
|