| 1 | AQP2, FXYD1
|
| Impaired AQP2 trafficking in Fxyd1 knockout mice: A role for FXYD1 in regulated vesicular transport.
|
| Arystarkhova E, Bouley R, Liu YB, Sweadner KJ.
|
| PLoS One 12(11):e0188006. doi: 10.1371/journal.pone.0188006. eCollection 2017.
2017
|
| 2 | AQP2, VTA1
|
| Phosphorylation of human aquaporin 2 (AQP2) allosterically controls its interaction with the lysosomal trafficking protein LIP5.
|
| Roche JV, Survery S, Kreida S, Nesverova V, Ampah-Korsah H, Gourdon M, Deen PMT, Törnroth-Horsefield S.
|
| J Biol Chem 292(35):14636-14648. doi: 10.1074/jbc.M117.788364. Epub 2017 Jul 14.
2017
|
| 3 | AQP2, EZR
|
| Ezrin directly interacts with AQP2 and promotes its endocytosis.
|
| Li W, Jin WW, Tsuji K, Chen Y, Nomura N, Su L, Yui N, Arthur J, Cotecchia S, Paunescu TG, Brown D, Lu HAJ.
|
| J Cell Sci 130(17):2914-2925. doi: 10.1242/jcs.204842. Epub 2017 Jul 28.
2017
|
| 4 | AQP2, AVPR2, ELF5
|
| Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression
|
| Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K.
|
| Dev Biol. Apr 1;424(1):77-89. doi: 10.1016/j.ydbio.2017.02.007. Epub 2017 Feb 17. 2017
|
| 5 | AQP2, AQP3, KCNE1
|
| Ménière's Disease: Molecular Analysis of Aquaporins 2, 3 and Potassium Channel KCNE1 Genes in Brazilian Patients.
|
| Lopes Kde C, Sartorato EL, da Silva-Costa SM, de Macedo Adamov NS, Ganança FF.
|
| Otol Neurotol 37(8):1117-21. doi: 10.1097/MAO.0000000000001136.
2016
|
| 6 | AQP2, GATA2
|
| GATA2 regulates body water homeostasis through maintaining aquaporin 2 expression in renal collecting ducts.
|
| Yu L, Moriguchi T, Souma T, Takai J, Satoh H, Morito N, Engel JD, Yamamoto M.
|
| Mol Cell Biol 34(11):1929-41. doi: 10.1128/MCB.01659-13.
2014
|
| 7 | AQP2, NR1H4
|
| Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice.
|
| Zhang X, Huang S, Gao M, Liu J, Jia X, Han Q, Zheng S, Miao Y, Li S, Weng H, Xia X, Du S, Wu W, Gustafsson JÅ, Guan Y.
|
| Proc Natl Acad Sci U S A 111(6):2277-82. doi: 10.1073/pnas.1323977111. Epub 2014 Jan 24.
2014
|
| 8 | AQP2, CUL5
|
| Aquaporin-2 levels in vitro and in vivo are regulated by VACM-1, a cul 5 gene.
|
| Le IP, Schultz S, Andresen BT, Dewey GL, Zhao P, Listenberger L, Deen PM, Buchwalter A, Barney CC, Burnatowska-Hledin MA.
|
| Cell Physiol Biochem. 30(5):1148-58. doi: 10.1159/000343305. Epub 2012 Oct 5 2012
|
| 9 | AQP2
|
| Identification of estrogen response element in the aquaporin-2 gene that mediates estrogen-induced cell migration and invasion in human endometrial carcinoma.
|
| Zou LB, Zhang RJ, Tan YJ, Ding GL, Shi S, Zhang D, He RH, Liu AX, Wang TT, Leung PC, Sheng JZ, Huang HF.
|
| J Clin Endocrinol Metab 96(9):E1399-408. Epub 2011 Jun 29.
2011
|
| 10 | AQP2, TBC1D4
|
| Emerging role of Akt substrate protein AS160 in the regulation of AQP2 translocation.
|
| Kim HY, Choi HJ, Lim JS, Park EJ, Jung HJ, Lee YJ, Kim SY, Kwon TH.
|
| Am J Physiol Renal Physiol 301(1):F151-61. Epub 2011 Apr 20.
2011
|
| 11 | AQP2
|
| Regulation of AQP2 localization by S256 and S261 phosphorylation and ubiquitination.
|
| Tamma G, Robben JH, Trimpert C, Boone M, Deen PM.
|
| Am J Physiol Cell Physiol 300(3):C636-46. Epub 2010 Dec 9.
2011
|
| 12 | AQP2, VAMP8
|
| A role for VAMP8/endobrevin in surface deployment of the water channel aquaporin 2.
|
| Wang CC, Ng CP, Shi H, Liew HC, Guo K, Zeng Q, Hong W.
|
| Mol Cell Biol 30(1):333-43. Epub .
2010
|
| 13 | AQP2, AVPR2
|
| Expression of aquaporins and vasopressin type 2 receptor in the stria vascularis of the cochlea.
|
| Nishioka R, Takeda T, Kakigi A, Okada T, Takebayashi S, Taguchi D, Nishimura M, Hyodo M.
|
| Hear Res 260(1-2):11-9. Epub 2009 Sep 29.
2010
|
| 14 | AQP2, AVP, AVPR2
|
| Reciprocal regulation of aquaporin-2 abundance and degradation by protein kinase A and p38-MAP kinase.
|
| Nedvetsky PI, Tabor V, Tamma G, Beulshausen S, Skroblin P, Kirschner A, Mutig K, Boltzen M, Petrucci O, Vossenkämper A, Wiesner B, Bachmann S, Rosenthal W, Klussmann E.
|
| J Am Soc Nephrol 21(10):1645-56. Epub 2010 Aug 19.
2010
|
| 15 | AQP2
|
| Expression and translocation of aquaporin-2 in the endolymphatic sac in patients with Meniere's disease.
|
| Maekawa C, Kitahara T, Kizawa K, Okazaki S, Kamakura T, Horii A, Imai T, Doi K, Inohara H, Kiyama H.
|
| J Neuroendocrinol 22(11):1157-64. doi: 10.1111/j.1365-2826.2010.02060.x.
2010
|
| 16 | AQP2
|
| Adaptation to alkalosis induces cell cycle delay and apoptosis in cortical collecting duct cells: role of Aquaporin-2.
|
| Rivarola V, Flamenco P, Melamud L, Galizia L, Ford P, Capurro C.
|
| J Cell Physiol 224(2):405-13.
2010
|
| 17 | AQP2
|
| Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions.
|
| Moeller HB, Praetorius J, Rützler MR, Fenton RA.
|
| Proc Natl Acad Sci U S A 107(1):424-9. Epub 2009 Dec 4.
2010
|
| 18 | AQP1, AQP2, NFAT5
|
| The expression of aquaporin-1 in the medulla of the kidney is dependent on the transcription factor associated with hypertonicity, TonEBP.
|
| Lanaspa MA, Andres-Hernando A, Li N, Rivard CJ, Cicerchi C, Roncal-Jimenez C, Schrier RW, Berl T.
|
| J Biol Chem 285(41):31694-703. doi: 10.1074/jbc.M109.093690. Epub 2010 Jul 16.
2010
|
| 19 | AQP2, VTA1
|
| The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells.
|
| Boone M, Mobasheri A, Fenton RA, van Balkom BW, Wismans R, van der Zee CE, Deen PM.
|
| J Mol Histol 41(1):61-74. doi: 10.1007/s10735-010-9263-9. Epub 2010 Apr 1.
2010
|
| 20 | AQP1, AQP2, AQP3, AQP4, AQP5, AQP6, AQP7, AQP9
|
| Aquaporins as potential drug targets for Meniere's disease and its related diseases.
|
| Takeda T, Taguchi D.
|
| Handb Exp Pharmacol (190):171-84. Review.
2009
|
| 21 | AQP2, AVP
|
| Regulation of aquaporin-2 trafficking.
|
| Nedvetsky PI, Tamma G, Beulshausen S, Valenti G, Rosenthal W, Klussmann E.
|
| Handb Exp Pharmacol (190):133-57. Review.
2009
|
| 22 | AQP2
|
| Nucleotides downregulate aquaporin 2 via activation of apical P2 receptors.
|
| Wildman SS, Boone M, Peppiatt-Wildman CM, Contreras-Sanz A, King BF, Shirley DG, Deen PM, Unwin RJ.
|
| J Am Soc Nephrol 20(7):1480-90. Epub 2009 May 7.
2009
|
| 23 | AQP2, DIR2
|
| Compound heterozygous mutation of aquaporin 2 gene in woman patient with congenital nephrogenic diabetes insipidus.
|
| Tsutsumi Z, Inokuchi T, Tamada D, Moriwaki Y, Ka T, Takahashi S, Yamamoto T.
|
| Intern Med 48(6):437-40. Epub 2009 Mar 16.
2009
|
| 24 | AQP1, AQP10, AQP11, AQP12A, AQP2, AQP3, AQP4, AQP5, AQP6, AQP7, AQP8, AQP9, MIP
|
| Genetic variation in human aquaporins and effects on phenotypes of water homeostasis.
|
| Sorani MD, Manley GT, Giacomini KM.
|
| Hum Mutat 29(9):1108-17. Review. 2008
|
| 25 | AQP2
|
| Heat shock protein 70 interacts with aquaporin-2 and regulates its trafficking.
|
| Lu HA, Sun TX, Matsuzaki T, Yi XH, Eswara J, Bouley R, McKee M, Brown D.
|
| J Biol Chem 282(39):28721-32. Epub 2007 Jul 18. 2007
|
| 26 | DIR2, AQP2
|
| Congenital progressive hydronephrosis (cph) is caused by an S256L mutation in aquaporin-2 that affects its phosphorylation and apical membrane accumulation.
|
| McDill BW, Li SZ, Kovach PA, Ding L, Chen F.
|
| Proc Natl Acad Sci U S A 103(18):6952-7. Epub 2006 Apr 25. 2006
|
| 27 | AQP2, AVPR2, DIR1
|
| Nephrogenic diabetes insipidus.
|
| Bichet DG.
|
| Adv Chronic Kidney Dis 13(2):96-104. Review.
2006
|
| 28 | AQP2, DIR2
|
| A novel mechanism in recessive nephrogenic diabetes insipidus: wild-type aquaporin-2 rescues the apical membrane expression of intracellularly retained AQP2-P262L.
|
| de Mattia F, Savelkoul PJ, Bichet DG, Kamsteeg EJ, Konings IB, Marr N, Arthus MF, Lonergan M, van Os CH, van der Sluijs P, Robertson G, Deen PM.
|
| Hum Mol Genet 13(24):3045-56. Epub 2004 Dec 15. 2004
|
| 29 | AVP, AQP2, AKAP7
|
| Identification of a novel A-kinase anchoring protein 18 isoform and evidence for its role in the vasopressin-induced aquaporin-2 shuttle in renal principal cells.
|
| Henn V, Edemir B, Stefan E, Wiesner B, Lorenz D, Theilig F, Schmitt R, Vossebein L, Tamma G, Beyermann M, Krause E, Herberg FW, Valenti G, Bachmann S, Rosenthal W, Klussmann E.
|
| J Biol Chem 279(25):26654-65. Epub 2004 Mar 22. 2004
|
| 30 | AQP2, SIPA1
|
| Aquaporin-2 trafficking is regulated by PDZ-domain containing protein SPA-1.
|
| Noda Y, Horikawa S, Furukawa T, Hirai K, Katayama Y, Asai T, Kuwahara M, Katagiri K, Kinashi T, Hattori M, Minato N, Sasaki S.
|
| FEBS Lett 568(1-3):139-45. 2004
|
| 31 | AQP2
|
| Water channel aquaporin-2 directly binds to actin.
|
| Noda Y, Horikawa S, Katayama Y, Sasaki S.
|
| Biochem Biophys Res Commun 322(3):740-5. 2004
|
| 32 | AQP7, AQP3, AQP5, AQP1, AQP2, AQP7P1, AQP7P2, AQP7P3, AQP7P4
|
| Human aquaporin adipose (AQPap) gene. Genomic structure, promoter analysis and functional mutation.
|
| Kondo H, Shimomura I, Kishida K, Kuriyama H, Makino Y, Nishizawa H, Matsuda M, Maeda N, Nagaretani H, Kihara S, Kurachi Y, Nakamura T, Funahashi T, Matsuzawa Y.
|
| Eur J Biochem 269(7):1814-26. 2002
|
| 33 | AQP2, DIR2
|
| Cell-biologic and functional analyses of five new Aquaporin-2 missense mutations that cause recessive nephrogenic diabetes insipidus.
|
| Marr N, Bichet DG, Hoefs S, Savelkoul PJ, Konings IB, De Mattia F, Graat MP, Arthus MF, Lonergan M, Fujiwara TM, Knoers NV, Landau D, Balfe WJ, Oksche A, Rosenthal W, Muller D, Van Os CH, Deen PM.
|
| J Am Soc Nephrol 13(9):2267-77. 2002
|
| 34 | AQP2
|
| Aquaporin-2 expression in the mammalian cochlea and investigation of its role in Meniere's disease.
|
| hatre AN, Jero J, Chiappini I, Bolasco G, Barbara M, Lalwani AK.
|
| Hear Res 170(1-2):59-69. 2002
|
| 35 | AQP2, DIR2
|
| Three families with autosomal dominant nephrogenic diabetes insipidus caused by aquaporin-2 mutations in the C-terminus.
|
| Kuwahara M, Iwai K, Ooeda T, Igarashi T, Ogawa E, Katsushima Y, Shinbo I, Uchida S, Terada Y, Arthus MF, Lonergan M, Fujiwara TM, Bichet DG, Marumo F, Sasaki S.
|
| Am J Hum Genet 69(4):738-48. 2001
|
| 36 | DIR2, AQP2
|
| An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus.
|
| Kamsteeg EJ, et al.
|
| EMBO J 18(9):2394-2400. 1999
|
| 37 | AQP2, AVPR2, DIR1, DIR2
|
| Molecular analyses of the vasopressin type 2 receptor and aquaporin-2 genes in Brazilian kindreds with nephrogenic diabetes insipidus.
|
| Rocha JL, et al.
|
| Hum Mutat 14(3):233-239 1999
|
| 38 | AQP2, DIR2
|
| An aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complex.
|
| Mulders SM, et al.
|
| J Clin Invest 102 : 57-66. 1998
|
| 39 | AQP2, DIR2
|
| Novel mutations in aquaporin-2 gene in female siblings with nephrogenic diabetes insipidus : evidence of disrupted water channel function.
|
| Goji K, et al.
|
| J Clin Endocrinol Metab 83 : 3205-3209. 1998
|
| 40 | AQP2, DIR2
|
| Identification and characterization of aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus with partial vasopressin response.
|
| Canfield MC, Tamarappoo BK, Moses AM, Verkman AS, Holtzman EJ.
|
| Hum Mol Genet 6(11):1865-71. 1997
|
| 41 | AQP2, AVPR2
|
| Mutations in the vasopressin V2 receptor and aquaporin-2 genes in 12 families with congenital nephrogenic diabetes insipidus.
|
| Vargas-Poussou R, Forestier L, Dautzenberg MD, Niaudet P, Dechaux M, Antignac C.
|
| J Am Soc Nephrol 8(12):1855-62. 1997
|
| 42 | AQP2, DIR2
|
| Two novel mutations in the aquaporin-2 and the vasopressin V2 receptor genes in patients with congenital nephrogenic diabetes insipidus.
|
| Oksche A, et al.
|
| Hum Genet 98 : 587-589. 1996
|
| 43 | AQP2, MIP
|
| Human AQP2 and MIP genes, two members of the MIP family, map within chromosome band 12q13 on the basis of two-color FISH.
|
| Saito F, et al.
|
| Cytogenet Cell Genet 68 : 45-48. 1995
|
| 44 | AQP2
|
| Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct.
|
| Sasaki S, et al.
|
| J Clin Invest 93 : 1250-1256. 1994
|
| 45 | DIR2, AQP2
|
| Requirement of human renal water channel aquaporin-2 for vasopressin-dependent concentration of urine.
|
| Deen PMT, et al.
|
| Science 264 : 92-95. 1994
|
| 46 | AQP2
|
| Assignment of the human gene for the water channel of renal collecting duct aquaporin 2 (AQP2) to chromosome 12 region q12-q13.
|
| Deen PMT, et al.
|
| Cytogenet Cell Genet 66 : 260-262. 1994
|
| 47 | AQP2, DIR2
|
| Patients with autosomal nephrogenic diabetes insipidus homozygous for mutations in the aquaporin 2 Water-Channel gene.
|
| Van Lieburg AF, et al.
|
| Am J Hum Genet 55 : 648-652. 1994
|
| 48 | AQP2
|
| Isolation of human aquaporin-CD gene.
|
| Uchida S, et al.
|
| J Biol Chem 269 : 23451-23455. 1994
|