Citations for
1APP, CTSB
Wild type and mutant amyloid precursor proteins influence downstream effects of proteasome and autophagy inhibition.
Cecarini V, Bonfili L, Cuccioloni M, Mozzicafreddo M, Rossi G, Keller JN, Angeletti M, Eleuteri AM.
Biochim Biophys Acta 1842(2):127-34. doi: 10.1016/j.bbadis.2013.11.002. Epub 2013 Nov 8. 2014
2APOE, APP
ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions.
Verghese PB, Castellano JM, Garai K, Wang Y, Jiang H, Shah A, Bu G, Frieden C, Holtzman DM.
Proc Natl Acad Sci U S A 110(19):E1807-16. doi: 10.1073/pnas.1220484110. Epub 2013 Apr 25. 2013
3APBB1, APP, GULP1, LRP1
Engulfment adaptor phosphotyrosine-binding-domain-containing 1 (GULP1) is a nucleocytoplasmic shuttling protein and is transactivationally active together with low-density lipoprotein receptor-related protein 1 (LRP1).
Wahler A, Beyer AS, Keller IE, Schnack C, von Einem B, Pröpper C, Boeckers TM, Peltan ID, Strickland DK, Hyman BT, von Arnim CA.
Biochem J 450(2):333-43. doi: 10.1042/BJ20121100. 2013
4APOE, APP
Neurotoxicity of amyloid β-protein: synaptic and network dysfunction.
Mucke L, Selkoe DJ.
Cold Spring Harb Perspect Med 2(7):a006338. doi: 10.1101/cshperspect.a006338. Review. 2012
5APOE, APP
Differential regulation of amyloid-β endocytic trafficking and lysosomal degradation by apolipoprotein E isoforms.
Li J, Kanekiyo T, Shinohara M, Zhang Y, LaDu MJ, Xu H, Bu G.
J Biol Chem 287(53):44593-601. doi: 10.1074/jbc.M112.420224. Epub 2012 Nov 6. 2012
6AOPOE, APP
Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.
Hashimoto T, Serrano-Pozo A, Hori Y, Adams KW, Takeda S, Banerji AO, Mitani A, Joyner D, Thyssen DH, Bacskai BJ, Frosch MP, Spires-Jones TL, Finn MB, Holtzman DM, Hyman BT.
J Neurosci 32(43):15181-92. doi: 10.1523/JNEUROSCI.1542-12.2012. 2012
7APOE, APP
Apolipoprotein E promotes β-amyloid trafficking and degradation by modulating microglial cholesterol levels.
Lee CY, Tse W, Smith JD, Landreth GE.
J Biol Chem 287(3):2032-44. doi: 10.1074/jbc.M111.295451. Epub 2011 Nov 30. 2012
8APP, PTCH1, SHH, TRI21
APP-dependent up-regulation of Ptch1 underlies proliferation impairment of neural precursors in Down syndrome.
Trazzi S, Mitrugno VM, Valli E, Fuchs C, Rizzi S, Guidi S, Perini G, Bartesaghi R, Ciani E.
Hum Mol Genet 20(8):1560-73. Epub 2011 Jan 25. 2011
9APP, CD36
Scavenger receptor CD36 is essential for the cerebrovascular oxidative stress and neurovascular dysfunction induced by amyloid-beta.
Park L, Wang G, Zhou P, Zhou J, Pitstick R, Previti ML, Younkin L, Younkin SG, Van Nostrand WE, Cho S, Anrather J, Carlson GA, Iadecola C.
Proc Natl Acad Sci U S A 108(12):5063-8. Epub 2011 Mar 7. 2011
10APP, GAS1
Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein.
Chapuis J, Vingtdeux V, Campagne F, Davies P, Marambaud P.
Hum Mol Genet 20(10):2026-36. Epub 2011 Feb 28. 2011
11APP, GULP1
GULP1 is a novel APP-interacting protein that alters APP processing.
Hao Y, Perkinton MS, Chan WW, Chan HY, Miller CC, Lau KF.
Biochem J 436(3):631-9. Erratum in: Biochem J. 2011 Aug 1;437(3):576. Hao, Candy Yan [corrected to Hao, Yan]. 2011
12APP, NLGN1
The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?
Dinamarca MC, Weinstein D, Monasterio O, Inestrosa NC.
Biochemistry 50(38):8127-37. Epub 2011 Sep 1. 2011
13APP, CDH2
N-cadherin enhances APP dimerization at the extracellular domain and modulates Aβ production.
Asada-Utsugi M, Uemura K, Noda Y, Kuzuya A, Maesako M, Ando K, Kubota M, Watanabe K, Takahashi M, Kihara T, Shimohama S, Takahashi R, Berezovska O, Kinoshita A.
J Neurochem 119(2):354-63. doi: 10.1111/j.1471-4159.2011.07364.x. Epub 2011 Sep 20. 2011
14APBB1, APP, LRP1
Phosphorylation of LRP1 regulates the interaction with Fe65.
Klug W, Dietl A, Simon B, Sinning I, Wild K.
FEBS Lett 585(20):3229-35. doi: 10.1016/j.febslet.2011.09.028. Epub 2011 Sep 29. 2011
15APP, NTRK1
APP is phosphorylated by TrkA and regulates NGF/TrkA signaling.
Matrone C, Barbagallo AP, La Rosa LR, Florenzano F, Ciotti MT, Mercanti D, Chao MV, Calissano P, D'Adamio L.
J Neurosci 31(33):11756-61. doi: 10.1523/JNEUROSCI.1960-11.2011. 2011
16APP, TFRC
Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease.
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, Tanzi RE, Cappai R, Barnham KJ, Ciccotosto GD, Rogers JT, Bush AI.
Cell 142(6):857-67. 2010
17APBB1, APP, LRP2
Megalin interacts with APP and the intracellular adapter protein FE65 in neurons.
Alvira-Botero X, Pérez-Gonzalez R, Spuch C, Vargas T, Antequera D, Garzón M, Bermejo-Pareja F, Carro E.
Mol Cell Neurosci 45(3):306-15. Epub 2010 Jul 14. 2010
18AD1, APP
A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.
Di Fede G, Catania M, Morbin M, Rossi G, Suardi S, Mazzoleni G, Merlin M, Giovagnoli AR, Prioni S, Erbetta A, Falcone C, Gobbi M, Colombo L, Bastone A, Beeg M, Manzoni C, Francescucci B, Spagnoli A, Cantù L, Del Favero E, Levy E, Salmona M, Tagliavini F.
Science 323(5920):1473-7. 2009
19APP, IGF2R, PACS1, SORCS1, SORCS2, SORCS3, SORL1, SORT1
VPS10P-domain receptors - regulators of neuronal viability and function.
Willnow TE, Petersen CM, Nykjaer A.
Nat Rev Neurosci. 9(12):899-909. 2009
20APP
APP binds DR6 to trigger axon pruning and neuron death via distinct caspases.
Nikolaev A, McLaughlin T, O'Leary DD, Tessier-Lavigne M.
Nature 457(7232):981-9. 2009
21APP
Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75-NTR interaction.
Fombonne, J.; Rabizadeh, S.; Banwait, S.; Mehlen, P.; Bredesen, D. E.
Ann. Neurol. 65: 294-303 2009
22APBB1, APP, CNTN2
A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis.
Ma QH, Futagawa T, Yang WL, Jiang XD, Zeng L, Takeda Y, Xu RX, Bagnard D, Schachner M, Furley AJ, Karagogeos D, Watanabe K, Dawe GS, Xiao ZC.
Nat Cell Biol 10(3):283-94. Epub 2008 Feb 17. Erratum in: Nat Cell Biol. 2008 Apr;10(4):497. 2008
23AD1, AD2, AD24, AD3, AD4, APOE, APP, PSEN1, PSEN2
Genome-wide association studies in Alzheimer disease.
Waring SC, Rosenberg RN.
Arch Neurol 65(3):329-34. Review. 2008
24APP, BACE1, BACE2
Protein expression of BACE1, BACE2 and APP in Down syndrome brains.
Cheon MS, Dierssen M, Kim SH, Lubec G.
Amino Acids 35(2):339-43. Epub 2007 Dec 29. 2008
25APP, CCR2
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease.
El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD.
Nat Med 13(4):432-8. Epub 2007 Mar 11. 2007
26APP
Variations in the APP gene promoter region and risk of Alzheimer disease.
Guyant-Maréchal L, Rovelet-Lecrux A, Goumidi L, Cousin E, Hannequin D, Raux G, Penet C, Ricard S, Macé S, Amouyel P, Deleuze JF, Frebourg T, Brice A, Lambert JC, Campion D.
Neurology 68(9):684-7. 2007
27APP
Promoter mutations that increase amyloid precursor-protein expression are associated with Alzheimer disease.
Theuns J, Brouwers N, Engelborghs S, Sleegers K, Bogaerts V, Corsmit E, De Pooter T, van Duijn CM, De Deyn PP, Van Broeckhoven C.
Am J Hum Genet 78(6):936-46. Epub 2006 Apr 10. 2006
28APP, AD1
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy.
Rovelet-Lecrux A, Hannequin D, Raux G, Le Meur N, Laquerriere A, Vital A, Dumanchin C, Feuillette S, Brice A, Vercelletto M, Dubas F, Frebourg T, Campion D.
Nat Genet 38(1):24-6. Epub 2005 Dec 20. 2006
29UBE3A, SUMO1, APP
Genomic and functional profiling of duplicated chromosome 15 cell lines reveal regulatory alterations in UBE3A-associated ubiquitin-proteasome pathway processes.
Baron CA, Tepper CG, Liu SY, Davis RR, Wang NJ, Schanen NC, Gregg JP.
Hum Mol Genet 15(6):853-69. Epub 2006 Jan 30. 2006
30APP, AD1
Alzheimer dementia caused by a novel mutation located in the APP C-terminal intracytosolic fragment.
Theuns J, Marjaux E, Vandenbulcke M, Van Laere K, Kumar-Singh S, Bormans G, Brouwers N, Van den Broeck M, Vennekens K, Corsmit E, Cruts M, De Strooper B, Van Broeckhoven C, Vandenberghe R.
Hum Mutat 27(9):888-96. 2006
31AD1,APP
APP duplication is sufficient to cause early onset Alzheimer's dementia with cerebral amyloid angiopathy.
Sleegers K, Brouwers N, Gijselinck I, Theuns J, Goossens D, Wauters J, Del-Favero J, Cruts M, van Duijn CM, Van Broeckhoven C.
Brain 129(Pt 11):2977-83. Epub 2006 Aug 18. 2006
32AD1,APP
Phenotype associated with APP duplication in five families.
Cabrejo L, Guyant-Marechal L, Laquerriere A, Vercelletto M, De la Fourniere F, Thomas-Anterion C, Verny C, Letournel F, Pasquier F, Vital A, Checler F, Frebourg T, Campion D, Hannequin D.
Brain 129(Pt 11):2966-76. Epub 2006 Sep 7. 2006
33APP,CRYAB
alphaB-crystallin competes with Alzheimer's disease beta-amyloid peptide for peptide-peptide interactions and induces oxidation of Abeta-Met35.
Narayanan S, Kamps B, Boelens WC, Reif B.
FEBS Lett 580(25):5941-6. Epub 2006 Oct 5. 2006
34APP, MAPT
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Abeta and tau form soluble complexes that may promote self aggregation of both into the insoluble forms observed in Alzheimer's disease.
Proc Natl Acad Sci U S A. 103(6):1953-8. 2006
35APP, SORL1
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Andersen OM, Schmidt V, Spoelgen R, Gliemann J, Behlke J, Galatis D, McKinstry WJ, Parker MW, Masters CL, Hyman BT, Cappai R, Willnow TE.
Biochemistry. 45(8):2618-28. 2006
36APP
A specific amyloid-beta protein assembly in the brain impairs memory.
Lesne, S.; Koh, M. T.; Kotilinek, L.; Kayed, R.; Glabe, C. G.; Yang, A.; Gallagher, M.; Ashe, K. H.
Nature 440: 352-357 2006
37APP
NO synthase 2 (NOS2) deletion promotes multiple pathologies in a mouse model of Alzheimer's disease.
Colton CA, Vitek MP, Wink DA, Xu Q, Cantillana V, Previti ML, Van Nostrand WE, Weinberg JB, Dawson H.
Proc Natl Acad Sci U S A. 103(34):12867-72. 2006
38APP
The prolyl isomerase Pin1 regulates amyloid precursor protein processing and amyloid-beta production.
Pastorino L, Sun A, Lu PJ, Zhou XZ, Balastik M, Finn G, Wulf G, Lim J, Li SH, Li X, Xia W, Nicholson LK, Lu KP.
Nature 440(7083):528-34 2006
39AD1, AD24, AD3, APP, PSEN1
Molecular diagnosis of autosomal dominant early onset Alzheimer's disease: an update.
Raux G, Guyant-Marechal L, Martin C, Bou J, Penet C, Brice A, Hannequin D, Frebourg T, Campion D.
J Med Genet 42(10):793-5. Epub 2005 Jul 20. 2005
40APP, APLP2
Protease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis.
Xu F, Davis J, Miao J, Previti ML, Romanov G, Ziegler K, Van Nostrand WE.
Proc Natl Acad Sci U S A 102(50):18135-40. Epub 2005 Dec 5. 2005
41COL25A1, APP
Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site.
Soderberg L, Kakuyama H, Moller A, Ito A, Winblad B, Tjernberg LO, Naslund J.
J Biol Chem 280(2):1007-15. Epub 2004 Nov 1. 2005
42APP, HCHWAD
A novel AbetaPP mutation exclusively associated with cerebral amyloid angiopathy.
Obici L, Demarchi A, de Rosa G, Bellotti V, Marciano S, Donadei S, Arbustini E, Palladini G, Diegoli M, Genovese E, Ferrari G, Coverlizza S, Merlini G.
Ann Neurol 58(4):639-44. 2005
43APP
Homo- and heterodimerization of APP family members promotes intercellular adhesion.
Soba P, Eggert S, Wagner K, Zentgraf H, Siehl K, Kreger S, Löwer A, Langer A, Merdes G, Paro R, Masters CL, Müller U, Kins S, Beyreuther K.
EMBO J. 24(20):3624-34. 2005
44APP
The Alzheimer's A beta peptide induces neurodegeneration and apoptotic cell death in transgenic mice.
LaFerla FM, Tinkle BT, Bieberich CJ, Haudenschild CC, Jay G.
Nat Genet. 9(1):21-30. 2005
45APP
Brain estrogen deficiency accelerates A-beta plaque formation in an Alzheimer's disease animal model.
Yue, X.; Lu, M.; Lancaster, T.; Cao, P.; Honda, S.-I.; Staufenbiel, M.; Harada, N.; Zhong, Z.; Shen, Y.; Li, R.
Proc. Nat. Acad. Sci. 102: 19198-19203 2005
46APP
Regulation of cholesterol and sphingomyelin metabolism by amyloid-beta and presenilin.
Grimm, M. O. W.; Grimm, H. S.; Patzold, A. J.; Zinser, E. G.; Halonen, R.; Duering, M.; Tschape, J.-A.; De Strooper, B.; Muller, U.; Shen, J.; Hartmann, T.
Nature Cell Biol. 7: 1118-1123 2005
47APP
Suppression of mitochondrial succinate dehydrogenase, a primary target of beta-amyloid, and its derivative racemized at Ser residue.
Kaneko I, Yamada N, Sakuraba Y, Kamenosono M, Tutumi S.
J Neurochem. 68(1):437-9. 2005
48APP, HCHWAD
Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.
Herzig MC, Winkler DT, Burgermeister P, Pfeifer M, Kohler E, Schmidt SD, Danner S, Abramowski D, Stürchler-Pierrat C, Bürki K, van Duinen SG, Maat-Schieman ML, Staufenbiel M, Mathews PM, Jucker M.
Nat Neurosci 7(9):954-60. Epub 2004 Aug 15. 2004
49APP
The low density lipoprotein receptor-related protein 1B retains beta-amyloid precursor protein at the cell surface and reduces amyloid-beta peptide production.
Cam JA, Zerbinatti CV, Knisely JM, Hecimovic S, Li Y, Bu G.
J Biol Chem. 279(28):29639-46. 2004
50APP
Binding of F-spondin to amyloid-beta precursor protein: a candidate amyloid-beta precursor protein ligand that modulates amyloid-beta precursor protein cleavage.
Ho A, Südhof TC.
Proc Natl Acad Sci U S A. 101(8):2548-53. 2004
51APP
Alzheimer's disease-associated amyloid beta interacts with the human serine protease HtrA2/Omi.
Park HJ, Seong YM, Choi JY, Kang S, Rhim H.
Neurosci Lett. 357(1):63-7. 2004
52APP
Dissecting the pathological effects of human A-beta-40 and A-beta-42 in Drosophila: a potential model for Alzheimer's disease.
Iijima, K.; Liu, H.-P.; Chiang, A.-S.; Hearn, S. A.; Konsolaki, M.; Zhong, Y.
Proc Natl Acad Sci U S A. 101: 6623-6628, 2004. 2004
53APP
Identification of loci determining susceptibility to the lethal effects of amyloid precursor protein transgene overexpression.
Krezowski, J.; Knudson, D.; Ebeling, C.; Pitstick, R.; Giri, R. K.; Schenk, D.; Westaway, D.; Younkin, L.; Younkin, S. G.; Ashe, K. H.; Carlson, G. A.
Hum. Molec. Genet. 13: 1989-1997 2004
54APP
Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzheimer's disease.
Reddy PH, McWeeney S, Park BS, Manczak M, Gutala RV, Partovi D, Jung Y, Yau V, Searles R, Mori M, Quinn J.
Hum. Molec. Genet. 13(12):1225-40. 2004
55APP
A phosphorylated, carboxy-terminal fragment of beta-amyloid precursor protein localizes to the splicing factor compartment.
Muresan Z, Muresan V.
Hum Mol Genet. 13(5):475-88. 2004
56APP
Platelet amyloid precursor protein abnormalities in mild cognitive impairment predict conversion to dementia of Alzheimer type: a 2-year follow-up study.
Borroni B, Colciaghi F, Caltagirone C, Rozzini L, Broglio L, Cattabeni F, Di Luca M, Padovani A.
Arch Neurol 60(12):1740-4. 2003
57MMP2, APP
Identification of a region of beta-amyloid precursor protein essential for its gelatinase A inhibitory activity.
Higashi S, Miyazaki K.
J Biol Chem 278(16):14020-8. Epub 2003 Feb 13. 2003
58APP
Identification of a novel alternative splicing isoform of human amyloid precursor protein gene, APP639.
Tang K, Wang C, Shen C, Sheng S, Ravid R, Jing N.
Eur J Neurosci 18(1):102-8. 2003
59NCSTN, APP, PSEN1
Presenilin-1, nicastrin, amyloid precursor protein, and gamma-secretase activity are co-localized in the lysosomal membrane.
Pasternak SH, Bagshaw RD, Guiral M, Zhang S, Ackerley CA, Pak BJ, Callahan JW, Mahuran DJ.
J Biol Chem 278(29):26687-94. Epub 2003 May 7. 2003
60ETS2, APP
The chromosome 21 transcription factor ETS2 transactivates the beta-APP promoter: implications for Down syndrome.
Wolvetang EW, Bradfield OM, Tymms M, Zavarsek S, Hatzistavrou T, Kola I, Hertzog PJ.
Biochim Biophys Acta 1628(2):105-10. 2003
61APP, TGFB1
A direct interaction between transforming growth factor (TGF)-betas and amyloid-beta protein affects fibrillogenesis in a TGF-beta receptor-independent manner.
Mousseau DD, Chapelsky S, De Crescenzo G, Kirkitadze MD, Magoon J, Inoue S, Teplow DB, O'Connor-McCourt MD.
J Biol Chem. 278(40):38715-22. 2003
62APBB2, APBB3, APP
Generation of the beta-amyloid peptide and the amyloid precursor protein C-terminal fragment gamma are potentiated by FE65L1.
Chang Y, Tesco G, Jeong WJ, Lindsley L, Eckman EA, Eckman CB, Tanzi RE, Guénette SY.
J Biol Chem 278(51):51100-7. Epub 2003 Oct 3. 2003
63APP, LRP1
Distinct binding sites in the structure of alpha 2-macroglobulin mediate the interaction with beta-amyloid peptide and growth factors.
Mettenburg JM, Webb DJ, Gonias SL.
J Biol Chem 277(15):13338-45. 2002
64APP, SHC3
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.
Tarr PE, Roncarati R, Pelicci G, Pelicci PG, D'Adamio L.
J Biol Chem 277(19):16798-804. Epub 2002 Mar 04. 2002
65APP
Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide.
Cottingham MG, Hollinshead MS, Vaux DJ.
Biochemistry. 41(46):13539-47. 2002
66APP
Signal transduction through tyrosine-phosphorylated carboxy-terminal fragments of APP via an enhanced interaction with Shc/Grb2 adaptor proteins in reactive astrocytes of Alzheimer's disease brain.
Russo C, Dolcini V, Salis S, Venezia V, Violani E, Carlo P, Zambrano N, Russo T, Schettini G.
Ann N Y Acad Sci. 973:323-33. 2002
67APP
Evidence for binding of the ectodomain of amyloid precursor protein 695 and activated high molecular weight kininogen.
Das A, Smalheiser NR, Markaryan A, Kaplan A.
Biochim Biophys Acta. 1571(3):225-38. 2002
68APP
Jun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).
Scheinfeld MH, Roncarati R, Vito P, Lopez PA, Abdallah M, D'Adamio L.
J Biol Chem. 277(5):3767-75 2002
69APP
The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.
Roncarati R, Sestan N, Scheinfeld MH, Berechid BE, Lopez PA, Meucci O, McGlade JC, Rakic P, D'Adamio L.
Proc Natl Acad Sci U S A. 99(10):7102-7. 2002
70APP
Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha-7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins.
Dineley, K. T.; Xia, X.; Bui, D.; Sweatt, J. D.; Zheng, H.
J. Biol. Chem. 277: 22768-22780 2002
71APP
Differential roles of JIP scaffold proteins in the modulation of amyloid precursor protein metabolism.
Taru, H.; Kirino, Y.; Suzuki, T.
J. Biol. Chem. 277: 27567-27574 2002
72APP, PSEN1, PSEN2
Presenilin, Notch, and the genesis and treatment of Alzheimer's disease.
Selkoe DJ.
Proc Natl Acad Sci U S A 98(20):11039-41. 2001
73APP, NAE1
A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60.
Cao X, Sudhof TC.
Science 293(5527):115-20. 2001
74APP, TM2D2, TM2D3
beta -Amyloid peptide-induced apoptosis regulated by a novel protein containing a g protein activation module.
Kajkowski EM, Lo CF, Ning X, Walker S, Sofia HJ, Wang W, Edris W, ChandaP, Wagner E, Vile S, Ryan K, McHendry-Rinde B, Smith SC, Wood A, Rhodes KJ,Kennedy JD, Bard J, Jacobsen JS, Ozenberger BA.
J Biol Chem 276(22):18748-56. Epub 2001 Feb 20. 2001
75APP, HCHWAD
Dementia in hereditary cerebral hemorrhage with amyloidosis-Dutch type is associated with cerebral amyloid angiopathy but is independent of plaques and neurofibrillary tangles.
Natté R, Maat-Schieman ML, Haan J, Bornebroek M, Roos RA, van Duinen SG.
Ann Neurol 50(6):765-72. 2001
76ABL1, APP
The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.
Zambrano N, Bruni P, Minopoli G, Mosca R, Molino D, Russo C, Schettini G, Sudol M, Russo T.
J Biol Chem. 276(23):19787-92. 2001
77APP, CALR
Calreticulin functions as a molecular chaperone for the beta-amyloid precursor protein.
Johnson RJ, Xiao G, Shanmugaratnam J, Fine RE.
Neurobiol Aging. 22(3):387-95. 2001
78APP
Fibulin-1 binds the amino-terminal head of beta-amyloid precursor protein and modulates its physiological function.
Ohsawa I, Takamura C, Kohsaka S.
J Neurochem. 76(5):1411-20. 2001
79APP
Entactin-induced inhibition of human amyloid beta-protein fibril formation in vitro.
Kiuchi Y, Isobe Y, Fukushima K.
Neurosci Lett. 305(2):119-22. 2001
80APP
Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP
Lewis, J.; Dickson, D. W.; Lin, W.-L.; Chisholm, L.; Corral, A.; Jones, G.; Yen, S.-H.; Sahara, N.; Skipper, L.; Yager, D.; Eckman, C.; Hardy, J.; Hutton, M.; McGowan, E.
Science 293: 1487-1491 2001
81APP
Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP.
Kamal A, Almenar-Queralt A, LeBlanc JF, Roberts EA, Goldstein LS.
Nature 414(6864):643-8 2001
82APP
A transcriptionally active complex of APP with Fe65 and histone acetyltransferase Tip60.
Cao, X.; Sudhof, T. C.
Science 293: 115-120 2001
83APP, PRNP, PSEN1, PSEN2
High prevalence of pathogenic mutations in patients with early-onset dementia detected by sequence analyses of four different genes.
Finckh U, Muller-Thomsen T, Mann U, Eggers C, Marksteiner J, Meins W, Binetti G, Alberici A, Hock C, Nitsch RM, Gal A.
Am J Hum Genet 66(1):110-7. 2000
84APP
Nonfibrillar diffuse amyloid deposition due to a gamma(42)-secretase site mutation points to an essential role for N-truncated A beta(42) in Alzheimer's disease.
Kumar-Singh S, De Jonghe C, Cruts M, Kleinert R, Wang R, Mercken M, De Strooper B, Vanderstichele H, Lofgren A, Vanderhoeven I, Backhovens H, Vanmechelen E, Kroisel PM, Van Broeckhoven C.
Hum Mol Genet 9(18):2589-98. 2000
85APP, NCSTN, PSEN1
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P.
Nature 407(6800):48-54. 2000
86APP, KLC1
Axonal transport of amyloid precursor protein is mediated by direct binding to the kinesin light chain subunit of kinesin-I.
Kamal A, Stokin GB, Yang Z, Xia CH, Goldstein LS.
Neuron. 28(2):449-59. 2000
87APP
Human bleomycin hydrolase regulates the secretion of amyloid precursor protein.
Lefterov IM, Koldamova RP, Lazo JS.
FASEB J. 14(12):1837-47. 2000
88APP, PSEN1
Inhibiting amyloid precursor protein C-terminal cleavage promotes an interaction with presenilin 1.
Verdile G, Martins RN, Duthie M, Holmes E, St George-Hyslop PH, Fraser PE.
J Biol Chem. 275(27):20794-8. 2000
89APP, CHRNA7
beta-Amyloid(1-42) binds to alpha7 nicotinic acetylcholine receptor with high affinity. Implications for Alzheimer's disease pathology.
Wang HY, Lee DH, D'Andrea MR, Peterson PA, Shank RP, Reitz AB.
J Biol Chem. 275(8):5626-32. 2000
90APP
Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease.
Takahashi M, Doré S, Ferris CD, Tomita T, Sawa A, Wolosker H, Borchelt DR, Iwatsubo T, Kim SH, Thinakaran G, Sisodia SS, Snyder SH.
Neuron. 28(2):461-73. 2000
91APP, AD1
Unusual phenotypic alteration of beta amyloid precursor protein (betaAPP) maturation by a new val-715 --> met betaAPP-770 mutation responsible for probable early-onset Alzheimer's disease.
Ancolio K, et al.
Proc Natl Acad Sci U S A 96(7):4119-24. 1999
92APBA2, APP
Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein.
Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, Sakiyama S, Kirino Y, Suzuki T.
J Biol Chem 274(4):2243-54. 1999
93APBA3, APP
X11L2, a new member of the X11 protein family, interacts with Alzheimer's beta-amyloid precursor protein.
Tanahashi H, Tabira T.
Biochem Biophys Res Commun 255(3):663-7. 1999
94AD1, APP
Enhancer function and novel DNA binding protein activity in the near upstream betaAPP gene promoter.
Querfurth HW, et al.
Gene 232(1):125-41. 1999
95APBB3, APP
Molecular cloning of human Fe65L2 and its interaction with the Alzheimer's beta-amyloid precursor protein.
Tanahashi H, Tabira T.
Neurosci Lett 261(3):143-6. 1999
96APP
Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.
Homayouni R, Rice DS, Sheldon M, Curran T.
J Neurosci. 19(17):7507-15. 1999
97APP
Binding of gelsolin, a secretory protein, to amyloid beta-protein.
Chauhan VP, Ray I, Chauhan A, Wisniewski HM.
Biochem Biophys Res Commun. 258(2):241-6. 1999
98APP
Binding of amyloid beta-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer's disease.
Oppermann UC, Salim S, Tjernberg LO, Terenius L, Jörnvall H.
FEBS Lett. 451(3):238-42. 1999
99AD1, APP
Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala-Gly mutation.
Cras P, et al.
Acta Neuropathol 96 : 253-260. 1998
100APP, AD1
The role of A beta 42 in Alzheimer's disease.
Younkin SG.
J Physiol Paris 92(3-4):289-92. Review. 1998
101APP
PAT1, a microtubule-interacting protein, recognizes the basolateral sorting signal of amyloid precursor protein
Zheng P, Eastman J, Vande Pol S, Pimplikar SW.
Proc Natl Acad Sci U S A. 95(25):14745-50. 1998
102APP
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Xu H, Gouras GK, Greenfield JP, Vincent B, Naslund J, Mazzarelli L, Fried G, Jovanovic JN, Seeger M, Relkin NR, Liao F, Checler F, Buxbaum JD, Chait BT, Thinakaran G, Sisodia SS, Wang R, Greengard P, Gandy S.
Nat Med. 4(4):447-51. 1998
103APP
A novel method for making nested deletions and its application for sequencing of a 300 kb region of human APP locus.
Hattori M, et al.
Nucleic Acids Res 25 : 1802-1808. 1997
104APP, GRIK1, SOD1, DEL21QD, DEL21QT
High-resolution physical mapping of a 6.7-Mb YAC contig spanning a region critical for the monosomy 21 phenotype in 21q21.3-q22.1.
Orti R, Megarbane A, Maunoury C, Van Broeckhoven C, Sinet PM, Delabar JM.
Genomics 43(1):25-33. 1997
105AD1, APP
A new pathogenic mutation in the APP gene (I716V) increases the relative proportion of A beta 42(43).
Eckman CB, Mehta ND, Crook R, Perez-tur J, Prihar G, Pfeiffer E, Graff-Radford N, Hinder P, Yager D, Zenk B, Refolo LM, Prada CM, Younkin SG, Hutton M, Hardy J.
Hum Mol Genet 6(12):2087-9. 1997
106APP, PSEN1, PSEN2
Interaction between amyloid precursor protein and presenilins in mammalian cells: implications for the pathogenesis of Alzheimer disease.
Xia W, Zhang J, Perez R, Koo EH, Selkoe DJ.
Proc Natl Acad Sci U S A 94(15):8208-13. 1997
107APP, PSEN2
Formation of stable complexes between two Alzheimer's disease gene products: presenilin-2 and beta-amyloid precursor protein.
Weidemann A, Paliga K, Durrwang U, Czech C, Evin G, Masters CL, Beyreuther K.
Nat Med 3(3):328-32. 1997
108APP
Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC.
Jensen PH, Hojrup P, Hager H, Nielsen MS, Jacobsen L, Olesen OF, Gliemann J, Jakes R.
Biochem J. 323 ( Pt 2):539-46. 1997
109APP, AD1
Mutational screening of APP gene in patients with early-onset Alzheimer disease utilizing mismatched PCR-RFLP.
Nishiwaki Y, et al.
Clin Genet 49 : 119-123. 1996
110APP, AD1
Intrinsic signaling function of APP as a novel target of three V642 mutations linked to familial Alzheimer's disease.
Okamoto T, et al.
EMBO J 15 : 3769-3777. 1996
111APP, AGER
RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease.
Yan SD, et al.
Nature 382 : 685-691. 1996
112APP, NAE1
APP-BP1, a novel protein that binds to the carboxyl-terminal region of the amyloid precursor protein.
Chow N, Korenberg JR, Chen XN, Neve RL.
J Biol Chem 271 : 11339-11346. 1996
113APP
The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)
Multhaup G, Schlicksupp A, Hesse L, Beher D, Ruppert T, Masters CL, Beyreuther K.
Science 271(5254):1406-9. 1996
114APP, AD1
The Swedish mutation causes early-onset Alzheimer's disease by beta-secretase cleavage within the secretory pathway.
Haass C, et al.
Nat Med 1 : 1291-1296. 1995
115APP, AD1
A mutation in codon 717 of the amyloid precursor protein gene in an Australian family with Alzheimer's disease.
Brooks WS, et al.
Neurosci Lett 199 : 183-186. 1995
116APP
Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals.
Haass C, et al.
J Cell Biol 128(4):537-47 1995
117APP
Differential binding of vascular cell-derived proteoglycans (perlecan, biglycan, decorin, and versican) to the beta-amyloid protein of Alzheimer's disease.
Snow AD, Kinsella MG, Parks E, Sekiguchi RT, Miller JD, Kimata K, Wight TN.
Arch Biochem Biophys. 320(1):84-95 1995
118APP
Highly polymorphic repeat marker within the beta-amyloid precursor protein gene.
Zappata S, et al.
Hum Genet 93 : 85-86. 1994
119APP, AD1
Altered cleavage and secretion of a recombinant beta-APP bearing the Swedish familial Alzheimer's disease mutation.
Felsenstein KM, et al.
Nat Genet 6 : 251-254. 1994
120AD1, APP
Mutational analysis of the amyloid precursor protein gene in Japanese familial Alzheimer's disease kindreds.
Fujigasaki H, et al.
Hum Genet 93 : 460-462. 1994
121APP, AD1
Novel amyloid precursor protein gene mutation (Codon 665Asp) in a patient with late-onset Alzheimer's disease.
Peacock ML, et al.
Ann Neurol 35 : 432-438. 1994
122AD1, APP
Mutations associated with a locus for familial Alzheimer's disease result in alternative processing of amyloid beta-protein precursor.
Haass C, et al.
J Biol Chem 269 : 17741-17748. 1994
123APP, HCHWAD
The upstream promoter of the beta-amyloid precursor protein gene (APP) shows differential patterns of methylation in human brain.
Rogaev EI, et al.
Genomics 22 : 340-347. 1994
124AD1, APP
A large Swedish family with Alzheimer's disease with a codon 670/671 amyloid precursor protein mutation.
Axelman K, et al.
Arch Neurol 51 : 1193-1197. 1994
125APP
Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells.
Haass C, et al.
Proc Natl Acad Sci U S A 91(4):1564-8 1994
126APP
A highly informative microsatellite repeat polymorphism in intron 1 of the human amyloid precursor protein (APP) gene.
Tupler R, et al.
Hum Mol Genet 2 : 620. 1993
127APP
RFLP analysis for APP 717 mutations associated with Alzheimer's disease.
Zeldenrust SR, et al.
J Med Genet 30 : 476-478. 1993
128APP
Intraneuronal compartments of the amyloid precursor protein.
Ferreira A, et al.
J Neurosci 13(7):3112-23 1993
129APP, GAPDH
Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein.
Schulze H, Schuler A, Stüber D, Döbeli H, Langen H, Huber G.
J Neurochem. 60(5):1915-22. 1993
130APP
Long-distance restriction mapping of the proximal long arm of human chromosome 21 with Not I linking clones.
Ichikawa H, et al.
Proc Natl Acad Sci U S A 89 : 23-27. 1992
131APP
Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease : identification of a further family with APP717 Val-Ile.
Fidani L, et al.
Hum Mol Genet 1 : 165-168. 1992
132APP
Presenile dementia and cerebral haemorrhage linked to a mutation at codon-692 of the beta-amyloid precursor protein gene.
Hendriks L, et al.
Nat Genet 1 : 218-221. 1992
133APP
Mutation in codon-713 of the beta-amyloid precursor protein gene presenting with schizophrenia.
Jones CT, et al.
Nat Genet 1 : 306-308. 1992
134APP
A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid.
Mullan M, et al.
Nat Genet 1 : 345-347. 1992
135APP
A novel but non-pathogenic mutation in exon 4 of the human amyloid precursor protein (APP) gene.
Vaula G, et al.
Neurosci Lett 144 : 46-48. 1992
136APP, AD1
Molecular and prospective phenotypic characterization of a pedigree with familial Alzheimer's disease and a missense mutation in codon 717 of the beta-amyloid precursor protein gene.
Karlinsky H, et al.
Neurology 42 : 1445-1453. 1992
137APP
Improved direct sequencing of Alzheimer's amyloid precursor protein (APP) exons 16 and 17.
Adroer R, et al.
Neurosci Lett 141 : 69-71. 1992
138APP
Characterization of Alzheimer amyloid precursor protein transcripts in platelets and megakarocytes.
Gardella JE, et al.
Neurosci Lett 138 : 229-232. 1992
139AD1, AD2, APP
Molecular classification of Alzheimer's disease.
Hardy J, et al.
Lancet 337 : 1342-1343. 1991
140APP
Mononucleotide repeat polymorphism in the APP gene.
Mant R, et al.
Nucleic Acids Res 19 : 4572. 1991
141APP
APP717, APP693, and PRIP gene mutations are rare in Alzheimer disease.
Schellenberg GD, et al.
Am J Hum Genet 49 : 511-517. 1991
142APP
DNA diagnosis for hereditary cerebral hemorrhage with amyloidosis (Dutch type).
Bakker E, et al.
Am J Hum Genet 49 : 518-521. 1991
143APP
The 717val-Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups.
Yoshioka K, et al.
Biochem Biophys Res Commun 178 : 1141-1146. 1991
144APP
Early-onset Alzheimer's disease caused by mutations at codon 717 of the beta-amyloid precursor protein gene.
Chartier-Harlin MC, et al.
Nature 353 : 844-846. 1991
145APP
Screening for the beta-amyloid precursor protein mutation (APP717: Val-Ile) in extended pedigrees with early onset Alzheimer's disease.
Chartier-Harlin MC, et al.
Neurosci Lett 129 : 134-135. 1991
146APP
A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease.
Murrell J, et al.
Science 254 : 97-99. 1991
147AD1, APP
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease.
Goate A, et al.
Nature 349 : 704-706. 1991
148AD1, APP
Amyloid precursor protein gene mutation in early-onset Alzheimer's disease.
van Duijn CM, et al.
Lancet 337 : 978. 1991
149AD1, APP
Mis-sense mutation Val-Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease.
Naruse S, et al.
Lancet 337 : 978-979. 1991
150APP
Protease nexin-2/amyloid beta-protein precursor in blood is a platelet-specific protein.
Van Nostrand WE, et al.
Biochem Biophys Res Commun 175 : 15-21. 1991
151APP
Protease nexin-II (amyloid beta-protein precursor): a platelet alpha-granule protein.
Van Nostrand WE, et al.
Science 248 : 745-748. 1990
152APP
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
Levy E, et al.
Science 248 : 1124-1126. 1990
153APP
Amyloid beta protein precursor gene and hereditary cerebral hemorrhage with amyloidosis (Dutch).
Van Broeckhoven C, et al.
Science 248 : 1120-1122. 1990
154APP
Genomic organization of the human amyloid beta-protein precursor gene.
Yoshikai S, Sasaki H, Doh-ura K, Furuya H, Sakaki Y.
Gene 87(2):257-63. 1990
155APP, HCHWAD
Mutation of the Alzheimer's disease amyloid gene in hereditary cerebral hemorrhage, Dutch type.
Levy E, Carman MD, Fernandez-Madrid IJ, Power MD, Lieberburg I, van Duinen SG, Bots GT, Luyendijk W, Frangione B.
Science 248(4959):1124-6. 1990
156APP
Alpha 1-antichymotrypsin is associated solely with amyloid deposits containing the beta-protein. Amyloid and cell localization of alpha 1-antichymotrypsin.
Abraham CR, Shirahama T, Potter H.
Neurobiol Aging. 11(2):123-9. 1990
157APP
Protease nexin-II, a potent antichymotrypsin, shows identity to amyloid beta-protein precursor.
Van Nostrand WE, et al.
Nature 341 : 546-549. 1989
158APP
Mapping of the gene encoding the §-amyloid precursor protein and its relationship to the Down syndrome region of chromosome 21.
Patterson D, Gardiner K, Kao FT, Tanzi R, Watkins P, Gusella JF.
Proc Natl Acad Sci U S A 85 : 8266-8270. 1988
159APP
Amyloid beta protein precursor is possibly a heparan sulfate proteoglycan core protein.
Schubert D, Schroeder R, LaCorbiere M, Saitoh T, Cole G.
Science 241 : 223-226. 1988
160APP
Protease inhibitor domain encoded by an amyloid protein precursor mRNA associated with Alzheimer's disease.
Tanzi RE, et al.
Nature 331 : 528-530. 1988
161APP
Fine mapping of an Alzheimer disease-associated gene encoding beta-amyloid protein.
Jenkins EC, et al.
Biochem Biophys Res Commun 151 : 1-8. 1988
162APP
A high frequency NcoI RFLP detected in the Alzheimer amyloid peptide gene.
Wu Y, et al.
Nucleic Acids Res 16 : 1647. 1988
163APP, D21S11, D21S60, GART, SOD1
Irradiation-reduced human chromosome 21 hybrids.
Graw S, et al.
Somat Cell Mol Genet 14 : 233-242. 1988
164AD1, APP
Chromosome 21 physical map : familial Alzheimer-linked DNA sequences cluster in a probable hot spot of recombination.
Pulst SM, et al.
Am J Hum Genet 43 : A156. 1988
165APP
EcoT14I RFLP found at the human amyloid beta protein gene locus.
Taylor JE, et al.
Nucleic Acids Res 16 : 6259. 1988
166APP
Human amyloid beta protein gene locus : HaeIII RFLP.
Taylor JE, et al.
Nucleic Acids Res 16 : 7217. 1988
167APP
A new A4 amyloid mRNA contains a domain homologous to serine proteinase inhibitors.
Ponte P, et al.
Nature 331(6156):525-7 1988
168AD1, APP
Genetic linkage analysis of the Alzheimer's associated amyloid beta protein gene with familial Alzheimer's disease and chromosome 21.
Tanzi R, et al.
(HGM9) Cytogenet Cell Genet 46 : 703. 1987
169APP
Hereditary cerebral hemorrhage with amyloidosis in patients of Dutch origin is related to Alzheimer disease.
van Duinen SG, et al.
Proc Natl Acad Sci U S A 84 : 5991-5994. 1987
170APP
Sublocalization of the gene for the precursor of Alzheimer's disease amyloid A4 protein on chromosome 21.
Zabel BU, et al.
(HGM9) Cytogenet Cell Genet 46 : 725. 1987
171AD1, APP
Localization of amyloid § protein messenger RNA in brains from patients with Alzheimer's disease.
Bahmanyar S, et al.
Science 237 : 77-80. 1987
172APP
Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neutrinic (senile) plaques of people with Alzheimer disease and Down syndrome.
Robakis NK, et al.
Lancet I : 384-385. 1987
173APP
Conservation of brain amyloid protein in aged mammals and humans with Alzheimer's disease.
Selkoe DJ, et al.
Science 235 : 873-877. 1987
174APP
In situ hybridization of the §-amyloid protein (APP) cDNA to the vicinity of the interface of 21q21 and q22 in normal and Alzheimer's disease individuals.
Blanquet V, et al.
(HGM9) Cytogenet Cell Genet 46 : 582. 1987
175APP
Beta amyloid gene duplication in Alzheimer's disease and karyotypically normal Down syndrome.
Delabar JM, et al.
Science 235 : 1390-1392. 1987
176APP
Characterization and chromosomal localization of a cDNA encoding brain amyloid of Alzheimer's disease.
Goldgaber D, et al.
Science 235 : 877-880. 1987
177APP
The mouse homolog of the human amyloid beta protein (AD-AP) gene is located on the distal end of mouse chromosome 16 : further extension of the homology between human chromosome 21 and mouse chromosome 16.
Lovett M, et al.
Biochem Biophys Res Commun 144 : 1069-1075. 1987
178APP
Identification of a frequent DNA polymorphism for the A4-amyloid gene.
Horsthemke B, et al.
(HGM9) Cytogenet Cell Genet 46 : 630. 1987
179APP
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor.
Kang J, et al.
Nature 325 : 733-736. 1987
180APP
Molecular cloning and characterization of cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides.
Robakis NK, et al.
Proc Natl Acad Sci U S A 84 : 4190-4194. 1987
181APP
The beta amyloid protein (AD-AP) cDNA hybridizes in normal and Alzheimer individuals near the interface of 21q21 and q22.1.
Blanquet V, et al.
Ann Genet 30 : 68-69. 1987
182APP
A new TaqI polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease.
David F, et al.
Nucleic Acids Res 15 : 9103. 1987
183APP
A HindIII polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease.
Sasaki H, et al.
Nucleic Acids Res 15 : 6309. 1987
184APP, AD1
Beta-amyloid gene is not present in three copies in autopsy-validated Alzheimer's disease.
Warren AC, et al.
Genomics 1 : 307-312. 1987
185APP, AD1
Rearrangement of chromosome 21 in Alzheimer's disease.
Delabar JM, et al.
Ann Genet 29 : 226-228. 1986