| 1 | APBB1IP, RABGEF1
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| The Rap1-RIAM-talin axis of integrin activation and blood cell function.
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| Lagarrigue F, Kim C, Ginsberg MH.
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| Blood lood. 2016 May 20. pii: blood-2015-12-638700. [Epub ahead of print]
2016
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| 2 | APBB1IP
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| A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration.
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| Lagarrigue F, Vikas Anekal P, Lee HS, Bachir AI, Ablack JN, Horwitz AF, Ginsberg MH.
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| Nat Commun 6:8492. doi: 10.1038/ncomms9492.
2015
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| 3 | APBB1IP, RAP1A, RASSF5
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| Rap1 and its effector RIAM are required for lymphocyte trafficking.
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| Su W, Wynne J, Pinheiro EM, Strazza M, Mor A, Montenont E, Berger J, Paul DS, Bergmeier W, Gertler FB, Philips MR.
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| Blood 126(25):2695-703. doi: 10.1182/blood-2015-05-644104. Epub 2015 Aug 31. 2015
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| 4 | APBB1IP
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| Conformational activation of talin by RIAM triggers integrin-mediated cell adhesion.
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| Yang J, Zhu L, Zhang H, Hirbawi J, Fukuda K, Dwivedi P, Liu J, Byzova T, Plow EF, Wu J, Qin J.
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| Nat Commun 5:5880. doi: 10.1038/ncomms6880.
2014
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| 5 | APBB1IP, RAP1A
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| The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism.
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| Zhang H, Chang YC, Brennan ML, Wu J.
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| J Mol Cell Biol 6(2):128-39. doi: 10.1093/jmcb/mjt044. Epub 2013 Nov 28.
2014
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| 6 | APBB1IP, VCL
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| RIAM and vinculin binding to talin are mutually exclusive and regulate adhesion assembly and turnover.
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| Goult BT, Zacharchenko T, Bate N, Tsang R, Hey F, Gingras AR, Elliott PR, Roberts GC, Ballestrem C, Critchley DR, Barsukov IL.
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| J Biol Chem 288(12):8238-49. doi: 10.1074/jbc.M112.438119. Epub 2013 Feb 6. 2013
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| 7 | APBB1IP, RABGEF1
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| RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis.
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| Medraño-Fernandez I, Reyes R, Olazabal I, Rodriguez E, Sanchez-Madrid F, Boussiotis VA, Reche PA, Cabañas C, Lafuente EM.
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| Cell Mol Life Sci 70(13):2395-410. doi: 10.1007/s00018-013-1268-6. Epub 2013 Feb 19.
2013
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| 8 | APBB1IP, RABGEF1
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| Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector.
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| Wynne JP, Wu J, Su W, Mor A, Patsoukis N, Boussiotis VA, Hubbard SR, Philips MR.
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| J Cell Biol 199(2):317-30. doi: 10.1083/jcb.201201157. Epub 2012 Oct 8.
2012
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| 9 | APBB1IP
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| Focal adhesion disassembly is regulated by a RIAM to MEK-1 pathway.
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| Coló GP, Hernández-Varas P, Lock J, Bartolomé RA, Arellano-Sánchez N, Strömblad S, Teixidó J.
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| J Cell Sci 125(Pt 22):5338-52. doi: 10.1242/jcs.105270. Epub 2012 Sep 3.
2012
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| 10 | APBB1IP
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| RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.
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| Lee HS, Lim CJ, Puzon-McLaughlin W, Shattil SJ, Ginsberg MH.
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| J Biol Chem 284(8):5119-27. doi: 10.1074/jbc.M807117200. Epub 2008 Dec 19.
2009
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| 11 | APBB1IP, PLCG1
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| RIAM regulates the cytoskeletal distribution and activation of PLC-gamma1 in T cells.
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| Patsoukis N, Lafuente EM, Meraner P, Kim Js, Dombkowski D, Li L, Boussiotis VA.
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| Sci Signal 2(99):ra79. doi: 10.1126/scisignal.2000409.
2009
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| 12 | VASP, APBB1IP
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| PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins.
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| Jenzora A, Behrendt B, Small JV, Wehland J, Stradal TE.
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| FEBS Lett 579(2):455-63. 2005
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| 13 | APBB1IP, ARHGAP21, MASTL, PRTFDC1, ANKRD26, GPR158, THC2, PDSS1
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| FLJ14813 missense mutation: a candidate for autosomal dominant thrombocytopenia on human chromosome 10.
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| Gandhi MJ, Cummings CL, Drachman JG.
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| Hum Hered 55(1):66-70. 2003
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