Citations for
1AP2M1, MRD60
A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy.
Helbig I, Lopez-Hernandez T, Shor O, Galer P, Ganesan S, Pendziwiat M, Rademacher A, Ellis CA, Hümpfer N, Schwarz N, Seiffert S, Peeden J, Shen J, Štěrbová K, Hammer TB, Møller RS, Shinde DN, Tang S, Smith L, Poduri A, Krause R, Benninger F, Helbig KL, Haucke V, Weber YG; EuroEPINOMICS-RES Consortium; GRIN Consortium.
Am J Hum Genet 104(6):1060-1072. doi: 10.1016/j.ajhg.2019.04.001. Epub 2019 May 16. 2019
The AP2M1 gene expression is a promising biomarker for predicting survival of patients with hepatocellular carcinoma.
Cho SH, Pak K, Jeong DC, Han ME, Oh SO, Kim YH.
J Cell Biochem 120(3):4140-4146. doi: 10.1002/jcb.27699. Epub 2018 Sep 27. 2019
Disruption of adaptor protein 2μ (AP-2μ) in cochlear hair cells impairs vesicle reloading of synaptic release sites and hearing.
Jung S, Maritzen T, Wichmann C, Jing Z, Neef A, Revelo NH, Al-Moyed H, Meese S, Wojcik SM, Panou I, Bulut H, Schu P, Ficner R, Reisinger E, Rizzoli SO, Neef J, Strenzke N, Haucke V, Moser T.
EMBO J 34(21):2686-702. doi: 10.15252/embj.201591885. Epub 2015 Oct 7. 2015
Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy.
Tian Y, Chang JC, Fan EY, Flajolet M, Greengard P.
Proc Natl Acad Sci U S A 110(42):17071-6. doi: 10.1073/pnas.1315110110. Epub 2013 Sep 25. 2013
Identification and targeting of an interaction between a tyrosine motif within hepatitis C virus core protein and AP2M1 essential for viral assembly.
Neveu G, Barouch-Bentov R, Ziv-Av A, Gerber D, Jacob Y, Einav S.
PLoS Pathog 8(8):e1002845. doi: 10.1371/journal.ppat.1002845. Epub 2012 Aug 16. 2012
6AP2M1, RNF111
Arkadia complexes with clathrin adaptor AP2 and regulates EGF signalling.
Mizutani A, Saitoh M, Imamura T, Miyazawa K, Miyazono K.
J Biochem 148(6):733-41. doi: 10.1093/jb/mvq127. Epub 2010 Oct 21. 2010
Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking.
Van den Oever MC, Goriounova NA, Wan Li K, Van der Schors RC, Binnekade R, Schoffelmeer AN, Mansvelder HD, Smit AB, Spijker S, De Vries TJ.
Nat Neurosci at Neurosci. 2008 Aug 1. [Epub ahead of print]PMID: 18677306 2008
8AP2M1, MEGF10
MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.
Suzuki E, Nakayama M.
Exp Cell Res 313(17):3729-42. Epub 2007 Jul 3.PMID: 17643423 2007
9AP1M1, AP2M1
Molecular bases for the recognition of tyrosine-based sorting signals.
Bonifacino JS, Dell'Angelica EC.
J Cell Biol 145(5):923-6. Review. No abstract available 1999
10AP2M1, CTLA4
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein.
Zhang Y, Allison JP.
Proc Natl Acad Sci U S A 94(17):9273-8. 1997
11AP2M1, CTLA4
Interaction of CTLA-4 with the clathrin-associated protein AP50 results in ligand-independent endocytosis that limits cell surface expression.
Chuang E, Alegre ML, Duckett CS, Noel PJ, Vander Heiden MG, Thompson CB.
J Immunol 159(1):144-51. 1997
12AP2B1, VCP, AP2M1
Chromosome localization of human genes for clathrin adaptor polypeptides AP2beta and AP50 and the clathrin-binding protein, VCP.
Druck T, et al.
Genomics 30 : 94-97. 1995
Activity and in vitro reassembly of the coated vesicle (H+)-ATPase requires the 50-kDa subunit of the clathrin assembly complex AP-2.
Liu Q, Feng Y, Forgac M.
J Biol Chem 269(50):31592-7 1994
The 50 kDa protein subunit of assembly polypeptide (AP) AP-2 adaptor from clathrin-coated vesicles is phosphorylated on threonine-156 by AP-1 and a soluble AP50 kinase which co-purifies with the assembly polypeptides.
Pauloin A, Thurieau C.
Biochem J 296 ( Pt 2):409-15.PMID: 8257432 1993
Molecular cloning and complete amino acid sequence of AP50, an assembly protein associated with clathrin-coates vesicles.
Thurieau C, et al.
DNA 7 : 663-669. 1988