Citations for
1ANK2, PRX
Ankyrin-B directs membrane tethering of periaxin and is required for maintenance of lens fiber cell hexagonal shape and mechanics.
Maddala R, Walters M, Brophy PJ, Bennett V, Rao PV.
Am J Physiol Cell Physiol 310(2):C115-26. doi: 10.1152/ajpcell.00111.2015. Epub 2015 Nov 4. 2016
2ANK2, RAB22A, RABGAP1L
Ankyrin-B is a PI3P effector that promotes polarized α5β1-integrin recycling via recruiting RabGAP1L to early endosomes. 2016 PMID:
Qu F, Lorenzo DN, King SJ, Brooks R, Bear JE, Bennett V
Elife Oct 8;5:e20417. doi: 10.7554/eLife.20417. 2016
3ANK2, ARSG, CDH13, DCLK1, GRM8, RIMBP2, SLC16A6
Expression and replication studies to identify new candidate genes involved in normal hearing function.
Girotto G, Vuckovic D, Buniello A, Lorente-Cánovas B, Lewis M, Gasparini P, Steel KP.
PLoS One 9(1):e85352. doi: 10.1371/journal.pone.0085352. eCollection 2014. Erratum in: PLoS One. 2014;9(3):e91446. 2014
4ABCC8, ANK2, CAMK2A, CAMK2D, KCNJ11, SPTBN4
βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells.
Kline CF, Wright PJ, Koval OM, Zmuda EJ, Johnson BL, Anderson ME, Hai T, Hund TJ, Mohler PJ.
Proc Natl Acad Sci U S A 110(43):17576-81. doi: 10.1073/pnas.1314195110. Epub 2013 Oct 7. 2013
5ANK2, OBSCN
Obscurin is required for ankyrinB-dependent dystrophin localization and sarcolemma integrity.
Randazzo D, Giacomello E, Lorenzini S, Rossi D, Pierantozzi E, Blaauw B, Reggiani C, Lange S, Peter AK, Chen J, Sorrentino V.
J Cell Biol 200(4):523-36. doi: 10.1083/jcb.201205118. 2013
6ANK2
Defects in ankyrin-based membrane protein targeting pathways underlie atrial fibrillation.
Cunha SR, Hund TJ, Hashemi S, Voigt N, Li N, Wright P, Koval O, Li J, Gudmundsson H, Gumina RJ, Karck M, Schott JJ, Probst V, Le Marec H, Anderson ME, Dobrev D, Wehrens XH, Mohler PJ.
Circulation 124(11):1212-22. Epub 2011 Aug 22. 2011
7ANK2, DCTN4, DMD
Ankyrin-B interactions with spectrin and dynactin-4 are required for dystrophin-based protection of skeletal muscle from exercise injury.
Ayalon G, Hostettler JD, Hoffman J, Kizhatil K, Davis JQ, Bennett V.
J Biol Chem 286(9):7370-8. Epub 2010 Dec 25. 2011
8ANK2, KCNJ11, LQT4
Ankyrin-B regulates Kir6.2 membrane expression and function in heart.
Li J, Kline CF, Hund TJ, Anderson ME, Mohler PJ.
J Biol Chem 285(37):28723-30. Epub 2010 Jul 7. 2010
9ANK2
Functional anatomy of the murine sinus node: high-resolution optical mapping of ankyrin-B heterozygous mice.
Glukhov AV, Fedorov VV, Anderson ME, Mohler PJ, Efimov IR.
Am J Physiol Heart Circ Physiol 299(2):H482-91. Epub 2010 Jun 4. 2010
10ANK2, OBSCN
Oxidized calmodulin kinase II regulates conduction following myocardial infarction: a computational analysis.
Christensen MD, Dun W, Boyden PA, Anderson ME, Mohler PJ, Hund TJ.
PLoS Comput Biol 5(12):e1000583. Epub 2009 Dec 4. 2009
11ITPR3, ANK2, ATP1A1
Ankyrin B modulates the function of Na,K-ATPase/inositol 1,4,5-trisphosphate receptor signaling microdomain.
Liu X, Spicarov‡ Z, Rydholm S, Li J, Brismar H, Aperia A.
J Biol Chem 283(17):11461-8. Epub 2008 Feb 26. 2008
12ANK2, ANK3, DAG1, DCTN4, DMD
An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.
Ayalon G, Davis JQ, Scotland PB, Bennett V.
Cell 135(7):1189-200. 2008
13ANK2, OBSCN
Obscurin targets ankyrin-B and protein phosphatase 2A to the cardiac M-line.
Cunha SR, Mohler PJ.
J Biol Chem 283(46):31968-80. Epub 2008 Sep 9. 2008
14ANK2
Common genetic variants in ANK2 modulate QT interval: results from the KORA study.
Sedlacek K, Stark K, Cunha SR, Pfeufer A, Weber S, Berger I, Perz S, Kääb S, Wichmann HE, Mohler PJ, Hengstenberg C, Jeron A.
Circ Cardiovasc Genet 1(2):93-9. Epub 2008 Dec 9. 2008
15ANK2
Defining the cellular phenotype of "ankyrin-B syndrome" variants: human ANK2 variants associated with clinical phenotypes display a spectrum of activities in cardiomyocytes.
Mohler PJ, Le Scouarnec S, Denjoy I, Lowe JS, Guicheney P, Caron L, Driskell IM, Schott JJ, Norris K, Leenhardt A, Kim RB, Escande D, Roden DM.
Circulation 115(4):432-41. Epub 2007 Jan 22. 2007
16ANK2
A cardiac arrhythmia syndrome caused by loss of ankyrin-B function.
Mohler PJ, Splawski I, Napolitano C, Bottelli G, Sharpe L, Timothy K, Priori SG, Keating MT, Bennett V.
Proc Natl Acad Sci U S A 101(24):9137-42. Epub 2004 Jun 03. 2004
17ANK2, SPTBN1
Ankyrin-B targets beta2-spectrin to an intracellular compartment in neonatal cardiomyocytes.
Mohler PJ, Yoon W, Bennett V.
J Biol Chem 279(38):40185-93. Epub 2004 Jul 19. 2004
18ANK2, LQT4
Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death
Mohler PJ, Schott JJ, Gramolini AO, Dilly KW, Guatimosim S, duBell WH, Song LS, Haurogne K, Kyndt F, Ali ME, Rogers TB, Lederer WJ, Escande D, Le Marec H, Bennett V.
Nature 421(6923):634-9. 2003
19ANK2
Isolation and chromosomal localization of a novel nonerythroid ankyrin gene.
Tse WT, et al.
Genomics 10 : 858-866. 1991
20ANK2
Isolation and characterization of cDNAs encoding human brain ankyrins reveal a family of alternatively spliced genes.
Otto E, et al.
J Cell Biol 114 : 241-253. 1991
21ANK2
Isolation and sequence of a human brain ankyrin cDNA : evidence for a multigene family.
Otto E, et al.
J Cell Biol 109 : 264A. 1989