| 1 | ANGPTL3, ANGPTL3, ANGPTL4, LPL
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| On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity.
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| Kovrov O, Kristensen KK, Larsson E, Ploug M, Olivecrona G.
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| J Lipid Res. Apr;60(4):783-793. doi: 10.1194/jlr.M088807. Epub 2019 Jan 27 2019
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| 2 | ANGPTL3, ANGPTL8, LPL
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| ANGPTL8 requires ANGPTL3 to inhibit lipoprotein lipase and plasma triglyceride clearance.
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| Haller JF, Mintah IJ, Shihanian LM, Stevis P, Buckler D, Alexa-Braun CA, Kleiner S, Banfi S, Cohen JC, Hobbs HH, Yancopoulos GD, Murphy AJ, Gusarova V, Gromada J.
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| J Lipid Res. Jun;58(6):1166-1173. doi: 10.1194/jlr.M075689. Epub 2017 Apr 15 2017
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| 3 | ANGPTL3, ANGPTL8, LPL
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| ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase.
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| Chi X, Britt EC, Shows HW, Hjelmaas AJ, Shetty SK, Cushing EM, Li W, Dou A, Zhang R, Davies BSJ.
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| Mol Metab. Oct;6(10):1137-1149. doi: 10.1016/j.molmet.2017.06.014. Epub 2017 Jun 29 2017
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| 4 | ANGPTL3, FHBL2
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| Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism.
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| Minicocci I, Tikka A, Poggiogalle E, Metso J, Montali A, Ceci F, Labbadia G, Fontana M, Di Costanzo A, Maranghi M, Rosano A, Ehnholm C, Donini LM, Jauhiainen M, Arca M.
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| J Lipid Res 2016
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| 5 | ANGPTL3, ANGPTL8
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| Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome.
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| Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Kavalakatt S, Khadir A, Behbehani K, Alarouj M, Bennakhi A, Elkum N.
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| Cardiovasc Diabetol 15:25. doi: 10.1186/s12933-016-0346-0.
2016
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| 6 | ANGPTL3, FHBL2
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| The role of ANGPTL3 in controlling lipoprotein metabolism.
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| Tikka A, Jauhiainen M.
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| Endocrine 52(2):187-93. doi: 10.1007/s12020-015-0838-9. Epub 2016 Jan 11. Review.
2016
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| 7 | ANGPTL3
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| Angiopoietin-like protein 3 is an indicator of prognosis in esophageal cancer patients.
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| Zhu L, Jiang L, Wang W, Jia W, Liu F, Jiao X, Zhu X, Bao J, Yu H.
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| Int J Clin Exp Med 8(9):16101-6. eCollection 2015.
2015
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| 8 | ANGPTL3
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| Hepatic ANGPTL3 regulates adipose tissue energy homeostasis.
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| Wang Y, McNutt MC, Banfi S, Levin MG, Holland WL, Gusarova V, Gromada J, Cohen JC, Hobbs HH.
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| Proc Natl Acad Sci U S A 112(37):11630-5. doi: 10.1073/pnas.1515374112. Epub 2015 Aug 24.
2015
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| 9 | ANGPTL3
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| Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.
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| Wang Y, Gusarova V, Banfi S, Gromada J, Cohen JC, Hobbs HH.
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| J Lipid Res 56(7):1296-307. doi: 10.1194/jlr.M054882. Epub 2015 May 7.
2015
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| 10 | ANGPTL3
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| A novel role of angiopoietin-like-3 associated with podocyte injury.
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| Liu J, Gao X, Zhai Y, Shen Q, Sun L, Feng C, Rao J, Liu H, Zha X, Guo M, Ma D, Zhang Z, Li R, Xu H.
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| Pediatr Res 77(6):732-9. doi: 10.1038/pr.2015.38. Epub 2015 Feb 24.
2015
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| 11 | ANGPTL3
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| Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cells.
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| Farahbakhshian E, Verstegen MM, Visser TP, Kheradmandkia S, Geerts D, Arshad S, Riaz N, Grosveld F, van Til NP, Meijerink JP.
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| PLoS One 9(8):e105642. doi: 10.1371/journal.pone.0105642. eCollection 2014.
2014
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| 12 | ANGPTL3, FURIN
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| Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
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| Essalmani R, Susan-Resiga D, Chamberland A, Asselin MC, Canuel M, Constam D, Creemers JW, Day R, Gauthier D, Prat A, Seidah NG.
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| J Biol Chem 288(37):26410-8. doi: 10.1074/jbc.M113.501304. Epub 2013 Aug 5.
2013
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| 13 | ANGPTL3
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| The angiopoietin-like protein 3: a hepatokine with expanding role in metabolism.
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| Arca M, Minicocci I, Maranghi M.
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| Curr Opin Lipidol 24(4):313-20. doi: 10.1097/MOL.0b013e3283630cf0. Review.
2013
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| 14 | ANGPTL2, ANGPTL3
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| Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors.
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| Broxmeyer HE, Srour EF, Cooper S, Wallace CT, Hangoc G, Youn BS.
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| Blood Cells Mol Dis 48(1):25-9. doi: 10.1016/j.bcmd.2011.09.004. Epub 2011 Oct 7.
2012
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| 15 | ANGPTL3, FHBL2
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| Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.
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| Pisciotta L, Favari E, Magnolo L, Simonelli S, Adorni MP, Sallo R, Fancello T, Zavaroni I, Ardigň D, Bernini F, Calabresi L, Franceschini G, Tarugi P, Calandra S, Bertolini S.
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| Circ Cardiovasc Genet 5(1):42-50. doi: 10.1161/CIRCGENETICS.111.960674. Epub 2011 Nov 7.
2012
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| 16 | ANGPTL3, ANGPTL8
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| Atypical angiopoietin-like protein that regulates ANGPTL3.
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| Quagliarini F, Wang Y, Kozlitina J, Grishin NV, Hyde R, Boerwinkle E, Valenzuela DM, Murphy AJ, Cohen JC, Hobbs HH.
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| Proc Natl Acad Sci U S A 109(48):19751-6. doi: 10.1073/pnas.1217552109. Epub 2012 Nov 12.
2012
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| 17 | ANGPTL3, FHBL2
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| Identification of a novel mutation in the ANGPTL3 gene in two families diagnosed of familial hypobetalipoproteinemia without APOB mutation.
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| Martín-Campos JM, Roig R, Mayoral C, Martinez S, Martí G, Arroyo JA, Julve J, Blanco-Vaca F.
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| Clin Chim Acta 413(5-6):552-5. doi: 10.1016/j.cca.2011.11.020. Epub 2011 Nov 29.
2012
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| 18 | ANGPTL3, ANGPTL4, ANGPTL6
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| Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases.
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| Kadomatsu T, Tabata M, Oike Y.
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| FEBS J 278(4):559-64. doi: 10.1111/j.1742-4658.2010.07979.x. Epub 2010 Dec 23. Review.
2011
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| 19 | ANGPTL3
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| Angiopoietin-like protein 3 regulates the motility and permeability of podocytes by altering nephrin expression in vitro.
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| Gao X, Xu H, Liu H, Rao J, Li Y, Zha X.
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| Biochem Biophys Res Commun 399(1):31-6. Epub 2010 Jul 13.PMID: 20633534 2010
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| 20 | ANGPTL3, LPL, PCSK5
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| Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases.
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| Liu J, Afroza H, Rader DJ, Jin W.
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| J Biol Chem 285(36):27561-70. Epub 2010 Jun 26. 2010
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| 21 | ANGPTL3, ANGPTL4, ANGPTL5
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| Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events.
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| Miida T, Hirayama S.
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| Curr Opin Lipidol 21(1):70-5. doi: 10.1097/MOL.0b013e328333269e. Review.
2010
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| 22 | ANGPTL3, ANGPTL4
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| The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms.
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| Shan L, Yu XC, Liu Z, Hu Y, Sturgis LT, Miranda ML, Liu Q.
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| J Biol Chem 284(3):1419-24. Epub 2008 Nov 21.
2009
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| 23 | ANGPTL3, ANGPTL4
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| Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).
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| Lee EC, Desai U, Gololobov G, Hong S, Feng X, Yu XC, Gay J, Wilganowski N, Gao C, Du LL, Chen J, Hu Y, Zhao S, Kirkpatrick L, Schneider M, Zambrowicz BP, Landes G, Powell DR, Sonnenburg WK.
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| J Biol Chem 284(20):13735-45. Epub 2009 Mar 23.
2009
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| 24 | ANGPTL3, ANGPTL4, ANGPTL5
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| Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.
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| Romeo S, Yin W, Kozlitina J, Pennacchio LA, Boerwinkle E, Hobbs HH, Cohen JC.
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| J Clin Invest 119(1):70-9. doi: 10.1172/JCI37118. Epub 2008 Dec 15.
2009
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| 25 | ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4, ANGPTL5, ANGPTL7
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| Ontogeny of angiopoietin-like protein 1, 2, 3, 4, 5, and 7 genes during chick embryonic development.
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| Niki D, Katsu K, Yokouchi Y.
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| Dev Growth Differ 51(9):821-32. doi: 10.1111/j.1440-169X.2009.01145.x.
2009
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| 26 | ANGPTL3, ANGPTL4, ANGPTL6
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| The role of angiopoietin-like proteins in angiogenesis and metabolism.
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| Hato T, Tabata M, Oike Y.
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| Trends Cardiovasc Med 18(1):6-14. doi: 10.1016/j.tcm.2007.10.003. Review.
2008
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| 27 | ANGPTL3, FABP4
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| Angiopoietin-like protein 3: development, analytical characterization, and clinical testing of a new ELISA.
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| Stejskal D, Karpísek M, Humenanská V, Solichová P, Stejskal P.
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| Gen Physiol Biophys 26(3):230-3.
2007
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| 28 | ANGPTL3
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| Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase.
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| Shimamura M, Matsuda M, Yasumo H, Okazaki M, Fujimoto K, Kono K, Shimizugawa T, Ando Y, Koishi R, Kohama T, Sakai N, Kotani K, Komuro R, Ishida T, Hirata K, Yamashita S, Furukawa H, Shimomura I.
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| Arterioscler Thromb Vasc Biol 27(2):366-72. Epub 2006 Nov 16.
2007
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| 29 | ANGPTL3
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| Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo.
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| Ono M, Shimizugawa T, Shimamura M, Yoshida K, Noji-Sakikawa C, Ando Y, Koishi R, Furukawa H.
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| J Biol Chem 278(43):41804-9. Epub 2003 Aug 8. 2003
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| 30 | ANGPTL3
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| Regulation of the angiopoietin-like protein 3 gene by LXR.
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| Kaplan R, Zhang T, Hernandez M, Gan FX, Wright SD, Waters MG, Cai TQ.
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| J Lipid Res 44(1):136-43. 2003
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| 31 | ANGPTL3
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| Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes.
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| Shimamura M, Matsuda M, Kobayashi S, Ando Y, Ono M, Koishi R, Furukawa H, Makishima M, Shimomura I.
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| Biochem Biophys Res Commun 301(2):604-9. 2003
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| 32 | ANGPTL3
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| Angptl3 regulates lipid metabolism in mice.
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| Koishi R, Ando Y, Ono M, Shimamura M, Yasumo H, Fujiwara T, Horikoshi H, Furukawa H.
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| Nat Genet 30(2):151-7. 2002
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| 33 | ANGPTL3
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| ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.
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| Camenisch G, Pisabarro MT, Sherman D, Kowalski J, Nagel M, Hass P, Xie MH, Gurney A, Bodary S, Liang XH, Clark K, Beresini M, Ferrara N, Gerber HP.
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| J Biol Chem 277(19):17281-90. Epub 2002 Feb 27. 2002
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| 34 | ANGPTL3
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| Angiopoietin 5 : a novel human gene expressed specifically in liver.
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| Lewis K, et al.
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| unpublished 1999
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| 35 | ANGPTL3
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| Identification of a mammalian angiopoietin-related protein expressed specifically in liver.
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| Conklin D, Gilbertson D, Taft DW, Maurer MF, Whitmore TE, Smith DL, Walker KM, Chen LH, Wattler S, Nehls M, Lewis KB.
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| Genomics 62(3):477-82 1999
|