Citations for
1ANGPTL3, FHBL2
Effects of angiopoietin-like protein 3 deficiency on postprandial lipid and lipoprotein metabolism.
Minicocci I, Tikka A, Poggiogalle E, Metso J, Montali A, Ceci F, Labbadia G, Fontana M, Di Costanzo A, Maranghi M, Rosano A, Ehnholm C, Donini LM, Jauhiainen M, Arca M.
J Lipid Res 2016
2ANGPTL3, ANGPTL8
Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome.
Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Kavalakatt S, Khadir A, Behbehani K, Alarouj M, Bennakhi A, Elkum N.
Cardiovasc Diabetol 15:25. doi: 10.1186/s12933-016-0346-0. 2016
3ANGPTL3, FHBL2
The role of ANGPTL3 in controlling lipoprotein metabolism.
Tikka A, Jauhiainen M.
Endocrine 52(2):187-93. doi: 10.1007/s12020-015-0838-9. Epub 2016 Jan 11. Review. 2016
4ANGPTL3
Angiopoietin-like protein 3 is an indicator of prognosis in esophageal cancer patients.
Zhu L, Jiang L, Wang W, Jia W, Liu F, Jiao X, Zhu X, Bao J, Yu H.
Int J Clin Exp Med 8(9):16101-6. eCollection 2015. 2015
5ANGPTL3
Hepatic ANGPTL3 regulates adipose tissue energy homeostasis.
Wang Y, McNutt MC, Banfi S, Levin MG, Holland WL, Gusarova V, Gromada J, Cohen JC, Hobbs HH.
Proc Natl Acad Sci U S A 112(37):11630-5. doi: 10.1073/pnas.1515374112. Epub 2015 Aug 24. 2015
6ANGPTL3
Inactivation of ANGPTL3 reduces hepatic VLDL-triglyceride secretion.
Wang Y, Gusarova V, Banfi S, Gromada J, Cohen JC, Hobbs HH.
J Lipid Res 56(7):1296-307. doi: 10.1194/jlr.M054882. Epub 2015 May 7. 2015
7ANGPTL3
A novel role of angiopoietin-like-3 associated with podocyte injury.
Liu J, Gao X, Zhai Y, Shen Q, Sun L, Feng C, Rao J, Liu H, Zha X, Guo M, Ma D, Zhang Z, Li R, Xu H.
Pediatr Res 77(6):732-9. doi: 10.1038/pr.2015.38. Epub 2015 Feb 24. 2015
8ANGPTL3
Angiopoietin-like protein 3 promotes preservation of stemness during ex vivo expansion of murine hematopoietic stem cells.
Farahbakhshian E, Verstegen MM, Visser TP, Kheradmandkia S, Geerts D, Arshad S, Riaz N, Grosveld F, van Til NP, Meijerink JP.
PLoS One 9(8):e105642. doi: 10.1371/journal.pone.0105642. eCollection 2014. 2014
9ANGPTL3, FURIN
Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
Essalmani R, Susan-Resiga D, Chamberland A, Asselin MC, Canuel M, Constam D, Creemers JW, Day R, Gauthier D, Prat A, Seidah NG.
J Biol Chem 288(37):26410-8. doi: 10.1074/jbc.M113.501304. Epub 2013 Aug 5. 2013
10ANGPTL3
The angiopoietin-like protein 3: a hepatokine with expanding role in metabolism.
Arca M, Minicocci I, Maranghi M.
Curr Opin Lipidol 24(4):313-20. doi: 10.1097/MOL.0b013e3283630cf0. Review. 2013
11ANGPTL2, ANGPTL3
Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors.
Broxmeyer HE, Srour EF, Cooper S, Wallace CT, Hangoc G, Youn BS.
Blood Cells Mol Dis 48(1):25-9. doi: 10.1016/j.bcmd.2011.09.004. Epub 2011 Oct 7. 2012
12ANGPTL3, FHBL2
Characterization of three kindreds with familial combined hypolipidemia caused by loss-of-function mutations of ANGPTL3.
Pisciotta L, Favari E, Magnolo L, Simonelli S, Adorni MP, Sallo R, Fancello T, Zavaroni I, Ardigň D, Bernini F, Calabresi L, Franceschini G, Tarugi P, Calandra S, Bertolini S.
Circ Cardiovasc Genet 5(1):42-50. doi: 10.1161/CIRCGENETICS.111.960674. Epub 2011 Nov 7. 2012
13ANGPTL3, ANGPTL8
Atypical angiopoietin-like protein that regulates ANGPTL3.
Quagliarini F, Wang Y, Kozlitina J, Grishin NV, Hyde R, Boerwinkle E, Valenzuela DM, Murphy AJ, Cohen JC, Hobbs HH.
Proc Natl Acad Sci U S A 109(48):19751-6. doi: 10.1073/pnas.1217552109. Epub 2012 Nov 12. 2012
14ANGPTL3, FHBL2
Identification of a novel mutation in the ANGPTL3 gene in two families diagnosed of familial hypobetalipoproteinemia without APOB mutation.
Martín-Campos JM, Roig R, Mayoral C, Martinez S, Martí G, Arroyo JA, Julve J, Blanco-Vaca F.
Clin Chim Acta 413(5-6):552-5. doi: 10.1016/j.cca.2011.11.020. Epub 2011 Nov 29. 2012
15ANGPTL3, ANGPTL4, ANGPTL6
Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases.
Kadomatsu T, Tabata M, Oike Y.
FEBS J 278(4):559-64. doi: 10.1111/j.1742-4658.2010.07979.x. Epub 2010 Dec 23. Review. 2011
16ANGPTL3
Angiopoietin-like protein 3 regulates the motility and permeability of podocytes by altering nephrin expression in vitro.
Gao X, Xu H, Liu H, Rao J, Li Y, Zha X.
Biochem Biophys Res Commun 399(1):31-6. Epub 2010 Jul 13.PMID: 20633534 2010
17ANGPTL3, LPL, PCSK5
Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases.
Liu J, Afroza H, Rader DJ, Jin W.
J Biol Chem 285(36):27561-70. Epub 2010 Jun 26. 2010
18ANGPTL3, ANGPTL4, ANGPTL5
Impacts of angiopoietin-like proteins on lipoprotein metabolism and cardiovascular events.
Miida T, Hirayama S.
Curr Opin Lipidol 21(1):70-5. doi: 10.1097/MOL.0b013e328333269e. Review. 2010
19ANGPTL3, ANGPTL4
The angiopoietin-like proteins ANGPTL3 and ANGPTL4 inhibit lipoprotein lipase activity through distinct mechanisms.
Shan L, Yu XC, Liu Z, Hu Y, Sturgis LT, Miranda ML, Liu Q.
J Biol Chem 284(3):1419-24. Epub 2008 Nov 21. 2009
20ANGPTL3, ANGPTL4
Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL).
Lee EC, Desai U, Gololobov G, Hong S, Feng X, Yu XC, Gay J, Wilganowski N, Gao C, Du LL, Chen J, Hu Y, Zhao S, Kirkpatrick L, Schneider M, Zambrowicz BP, Landes G, Powell DR, Sonnenburg WK.
J Biol Chem 284(20):13735-45. Epub 2009 Mar 23. 2009
21ANGPTL3, ANGPTL4, ANGPTL5
Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans.
Romeo S, Yin W, Kozlitina J, Pennacchio LA, Boerwinkle E, Hobbs HH, Cohen JC.
J Clin Invest 119(1):70-9. doi: 10.1172/JCI37118. Epub 2008 Dec 15. 2009
22ANGPTL1, ANGPTL2, ANGPTL3, ANGPTL4, ANGPTL5, ANGPTL7
Ontogeny of angiopoietin-like protein 1, 2, 3, 4, 5, and 7 genes during chick embryonic development.
Niki D, Katsu K, Yokouchi Y.
Dev Growth Differ 51(9):821-32. doi: 10.1111/j.1440-169X.2009.01145.x. 2009
23ANGPTL3, ANGPTL4, ANGPTL6
The role of angiopoietin-like proteins in angiogenesis and metabolism.
Hato T, Tabata M, Oike Y.
Trends Cardiovasc Med 18(1):6-14. doi: 10.1016/j.tcm.2007.10.003. Review. 2008
24ANGPTL3, FABP4
Angiopoietin-like protein 3: development, analytical characterization, and clinical testing of a new ELISA.
Stejskal D, Karpísek M, Humenanská V, Solichová P, Stejskal P.
Gen Physiol Biophys 26(3):230-3. 2007
25ANGPTL3
Angiopoietin-like protein3 regulates plasma HDL cholesterol through suppression of endothelial lipase.
Shimamura M, Matsuda M, Yasumo H, Okazaki M, Fujimoto K, Kono K, Shimizugawa T, Ando Y, Koishi R, Kohama T, Sakai N, Kotani K, Komuro R, Ishida T, Hirata K, Yamashita S, Furukawa H, Shimomura I.
Arterioscler Thromb Vasc Biol 27(2):366-72. Epub 2006 Nov 16. 2007
26ANGPTL3
Protein region important for regulation of lipid metabolism in angiopoietin-like 3 (ANGPTL3): ANGPTL3 is cleaved and activated in vivo.
Ono M, Shimizugawa T, Shimamura M, Yoshida K, Noji-Sakikawa C, Ando Y, Koishi R, Furukawa H.
J Biol Chem 278(43):41804-9. Epub 2003 Aug 8. 2003
27ANGPTL3
Regulation of the angiopoietin-like protein 3 gene by LXR.
Kaplan R, Zhang T, Hernandez M, Gan FX, Wright SD, Waters MG, Cai TQ.
J Lipid Res 44(1):136-43. 2003
28ANGPTL3
Angiopoietin-like protein 3, a hepatic secretory factor, activates lipolysis in adipocytes.
Shimamura M, Matsuda M, Kobayashi S, Ando Y, Ono M, Koishi R, Furukawa H, Makishima M, Shimomura I.
Biochem Biophys Res Commun 301(2):604-9. 2003
29ANGPTL3
Angptl3 regulates lipid metabolism in mice.
Koishi R, Ando Y, Ono M, Shimamura M, Yasumo H, Fujiwara T, Horikoshi H, Furukawa H.
Nat Genet 30(2):151-7. 2002
30ANGPTL3
ANGPTL3 stimulates endothelial cell adhesion and migration via integrin alpha vbeta 3 and induces blood vessel formation in vivo.
Camenisch G, Pisabarro MT, Sherman D, Kowalski J, Nagel M, Hass P, Xie MH, Gurney A, Bodary S, Liang XH, Clark K, Beresini M, Ferrara N, Gerber HP.
J Biol Chem 277(19):17281-90. Epub 2002 Feb 27. 2002
31ANGPTL3
Angiopoietin 5 : a novel human gene expressed specifically in liver.
Lewis K, et al.
unpublished 1999
32ANGPTL3
Identification of a mammalian angiopoietin-related protein expressed specifically in liver.
Conklin D, Gilbertson D, Taft DW, Maurer MF, Whitmore TE, Smith DL, Walker KM, Chen LH, Wattler S, Nehls M, Lewis KB.
Genomics 62(3):477-82 1999