| 1 | AMOT, YAP1
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| Angiomotin promotes renal epithelial and carcinoma cell proliferation by retaining the nuclear YAP.
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| Lv M, Li S, Luo C, Zhang X, Shen Y, Sui Y, Wang F, Wang X, Yang J, Liu P, Yang J.
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| Oncotarget ncotarget. 2016 Feb 3. doi: 10.18632/oncotarget.7161. [Epub ahead of print]
2016
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| 2 | AMOT, ECM1, EDIL3
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| mRNA and protein expression of the angiogenesis-related genes EDIL3, AMOT and ECM1 in mesenchymal stem cells in psoriatic dermis.
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| Niu X, Chang W, Liu R, Hou R, Li J, Wang C, Li X, Zhang K.
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| Clin Exp Dermatol lin Exp Dermatol. 2015 Dec 8. doi: 10.1111/ced.12783. [Epub ahead of print]
2015
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| 3 | AMOT, RNF146, TNKS, YAP1
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| Tankyrase Inhibitors Target YAP by Stabilizing Angiomotin Family Proteins.
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| Wang W, Li N, Li X, Tran MK, Han X, Chen J.
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| Cell Rep 13(3):524-32. doi: 10.1016/j.celrep.2015.09.014. Epub 2015 Oct 8.
2015
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| 4 | AMOT
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| Angiomotin promotes breast cancer cell proliferation and invasion.
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| Lv M, Lv M, Chen L, Qin T, Zhang X, Liu P, Yang J.
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| Oncol Rep 33(4):1938-46. doi: 10.3892/or.2015.3780. Epub 2015 Feb 3.
2015
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| 5 | AMOT
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| Angiomotin is a novel component of cadherin-11/β-catenin/p120 complex and is critical for cadherin-11-mediated cell migration.
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| Ortiz A, Lee YC, Yu G, Liu HC, Lin SC, Bilen MA, Cho H, Yu-Lee LY, Lin SH.
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| FASEB J 29(3):1080-91. doi: 10.1096/fj.14-261594. Epub 2014 Dec 2.
2015
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| 6 | AMOT, MAMDC4, YAP1
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| Endosomal regulation of contact inhibition through the AMOT:YAP pathway.
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| Cox CM, Mandell EK, Stewart L, Lu R, Johnson DL, McCarter SD, Tavares A, Runyan R, Ghosh S, Wilson JM.
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| Mol Biol Cell 26(14):2673-84. doi: 10.1091/mbc.E15-04-0224. Epub 2015 May 20.
2015
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| 7 | AMOT, LATS1, LATS2
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| Angiomotins link F-actin architecture to Hippo pathway signaling.
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| Mana-Capelli S, Paramasivam M, Dutta S, McCollum D.
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| Mol Biol Cell 25(10):1676-85. doi: 10.1091/mbc.E13-11-0701. Epub 2014 Mar 19.
2014
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| 8 | AMOT, ITCH, YAP1
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| Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.
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| Adler JJ, Heller BL, Bringman LR, Ranahan WP, Cocklin RR, Goebl MG, Oh M, Lim HS, Ingham RJ, Wells CD.
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| J Biol Chem 288(21):15181-93. doi: 10.1074/jbc.M112.446534. Epub 2013 Apr 5.
2013
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| 9 | AMOT, MCAM
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| Soluble melanoma cell adhesion molecule (sMCAM/sCD146) promotes angiogenic effects on endothelial progenitor cells through angiomotin.
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| Stalin J, Harhouri K, Hubert L, Subrini C, Lafitte D, Lissitzky JC, Elganfoud N, Robert S, Foucault-Bertaud A, Kaspi E, Sabatier F, Aurrand-Lions M, Bardin N, Holmgren L, Dignat-George F, Blot-Chabaud M.
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| J Biol Chem 288(13):8991-9000. doi: 10.1074/jbc.M112.446518. Epub 2013 Feb 6.
2013
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| 10 | AMOT, ITCH, LATS1, LATS2, YAP1
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| Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases.
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| Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD.
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| Proc Natl Acad Sci U S A 110(43):17368-73. doi: 10.1073/pnas.1308236110. Epub 2013 Oct 7.
2013
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| 11 | AMOT, LATS1, LATS2
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| Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis.
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| Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B.
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| J Biol Chem 288(47):34041-51. doi: 10.1074/jbc.M113.518019. Epub 2013 Oct 8.
2013
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| 12 | AMOT, YAP1
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| The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis.
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| Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL.
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| Sci Signal 6(291):ra77. doi: 10.1126/scisignal.2004060.
2013
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| 13 | AMOT
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| Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation.
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| Chan SW, Lim CJ, Guo F, Tan I, Leung T, Hong W.
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| J Biol Chem 288(52):37296-307. doi: 10.1074/jbc.M113.527598. Epub 2013 Nov 13.
2013
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| 14 | AMOT, ITCH, NEDD4, NEDD4L
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| The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation.
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| Wang C, An J, Zhang P, Xu C, Gao K, Wu D, Wang D, Yu H, Liu JO, Yu L.
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| Biochem J 444(2):279-89. doi: 10.1042/BJ20111983.
2012
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| 15 | AMOT, AMOTL2, LATS2, YAP1
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| Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.
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| Murugan P, Sarkeshik A, Yates JR 3rd, McCollum D.
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| Mol Biol Cell ol Biol Cell. 2011 Aug 10. [Epub ahead of print] 2011
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| 16 | AMOT
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| The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.
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| Ranahan WP, Han Z, Smith-Kinnaman W, Nabinger SC, Heller B, Herbert BS, Chan R, Wells CD.
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| Cancer Res 71(6):2203-11. Epub 2011 Feb 1.
2011
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| 17 | AMOT, AMOTL1, WWTR1, YAP1
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| Hippo pathway-independent restriction of TAZ and YAP by angiomotin.
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| Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W.
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| J Biol Chem 286(9):7018-26. Epub 2011 Jan 11. 2011
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| 18 | AMOT, AMOTL2, WWTR1, YAP1
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| Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein.
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| Zhao B, Li L, Lu Q, Wang LH, Liu CY, Lei Q, Guan KL.
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| Genes Dev 25(1):51-63. 2011
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| 19 | AMOT, AMOTL1, AMOTL2, YAP1
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| Angiomotin-like proteins associate with and negatively regulate YAP1.
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| Wang W, Huang J, Chen J.
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| J Biol Chem 286(6):4364-70. Epub 2010 Dec 27.
2011
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| 20 | AMOT, ARHGAP17, NF2
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| A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions.
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| Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL.
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| Cancer Cell 19(4):527-40. doi: 10.1016/j.ccr.2011.02.017.
2011
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| 21 | AMOT
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| Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain.
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| Heller B, Adu-Gyamfi E, Smith-Kinnaman W, Babbey C, Vora M, Xue Y, Bittman R, Stahelin RV, Wells CD.
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| J Biol Chem 285(16):12308-20. Epub 2010 Jan 14.
2010
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| 22 | AMOT, INADL, MPDZ, PLEKHG5
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| The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.
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| Ernkvist M, Luna Persson N, Audebert S, Lecine P, Sinha I, Liu M, Schlueter M, Horowitz A, Aase K, Weide T, Borg JP, Majumdar A, Holmgren L.
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| Blood 113(1):244-53. Epub 2008 Sep 29.
2009
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| 23 | AMOT, AMOTL1
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| Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton.
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| Gagné V, Moreau J, Plourde M, Lapointe M, Lord M, Gagnon E, Fernandes MJ.
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| Cell Motil Cytoskeleton 66(9):754-68.
2009
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| 24 | AMOT, AMOTL1
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| Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis.
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| Zheng Y, Vertuani S, Nyström S, Audebert S, Meijer I, Tegnebratt T, Borg JP, Uhlén P, Majumdar A, Holmgren L.
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| Circ Res 105(3):260-70. Epub 2009 Jul 9.
2009
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| 25 | AMOT
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| Differential roles of p80- and p130-angiomotin in the switch between migration and stabilization of endothelial cells.
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| Ernkvist M, Birot O, Sinha I, Veitonmaki N, Nyström S, Aase K, Holmgren L.
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| Biochim Biophys Acta 1783(3):429-37. Epub 2007 Dec 8.
2008
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| 26 | AMOT
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| Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo.
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| Levchenko T, Veitonmäki N, Lundkvist A, Gerhardt H, Ming Y, Berggren K, Kvanta A, Carlsson R, Holmgren L.
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| FASEB J 22(3):880-9. Epub 2007 Nov 5.
2008
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| 27 | AMOT, AMOTL1, AMOTL2, INADL, MPDZ
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| Molecular characterization of angiomotin/JEAP family proteins: interaction with MUPP1/Patj and their endogenous properties.
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| Sugihara-Mizuno Y, Adachi M, Kobayashi Y, Hamazaki Y, Nishimura M, Imai T, Furuse M, Tsukita S.
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| Genes Cells 12(4):473-86.
2007
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| 28 | AMOT
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| Angiomotin regulates endothelial cell migration during embryonic angiogenesis.
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| Aase K, Ernkvist M, Ebarasi L, Jakobsson L, Majumdar A, Yi C, Birot O, Ming Y, Kvanta A, Edholm D, Aspenström P, Kissil J, Claesson-Welsh L, Shimono A, Holmgren L.
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| Genes Dev 21(16):2055-68.
2007
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| 29 | AMOT
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| p130-angiomotin associates to actin and controls endothelial cell shape.
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| Ernkvist M, Aase K, Ukomadu C, Wohlschlegel J, Blackman R, Veitonmaki N, Bratt A, Dutta A, Holmgren L.
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| FEBS J 273(9):2000-11. 2006
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| 30 | AMOT, ARHGAP17
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| A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.
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| Wells CD, Fawcett JP, Traweger A, Yamanaka Y, Goudreault M, Elder K, Kulkarni S, Gish G, Virag C, Lim C, Colwill K, Starostine A, Metalnikov P, Pawson T.
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| Cell 125(3):535-48. 2006
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| 31 | AMOT
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| Protein diversity is generated within the motin family of proteins by alternative pre-mRNA splicing.
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| Moreau J, Lord M, Boucher M, Belleau P, Fernandes MJ.
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| Gene 350(2):137-48. Epub 2005 Mar 29. 2005
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| 32 | AMOT
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| Angiomotin regulates endothelial cell-cell junctions and cell motility.
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| Bratt A, Birot O, Sinha I, Veitonmaki N, Aase K, Ernkvist M, Holmgren L.
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| J Biol Chem 280(41):34859-69. Epub 2005 Jul 25. 2005
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| 33 | AMOT, AMOTL1, AMOTL2
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| Angiomotin belongs to a novel protein family with conserved coiled-coil and PDZ binding domains.
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| Bratt A, Wilson WJ, Troyanovsky B, Aase K, Kessler R, Meir EG, Holmgren L.
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| Gene 298(1):69-77. 2002
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| 34 | AMOT
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| Angiomotin: an angiostatin binding protein that regulates endothelial cell migration and tube formation.
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| Troyanovsky B, Levchenko T, Mansson G, Matvijenko O, Holmgren L.
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| J Cell Biol 152(6):1247-54. 2001
|