Citations for
1ADM, AGTRAP, ALOX5, ENTPD1, IRAK3, MMP9, S100A8
Identification of key pathogenic genes of sepsis based on the Gene Expression Omnibus database.
Lu X, Xue L, Sun W, Ye J, Zhu Z, Mei H.
Mol Med Rep. Feb;17(2):3042-3054. doi: 10.3892/mmr.2017.8258. Epub 2017 Dec 12 2018
2ALOX5, RORA
Melatonin suppresses activation of hepatic stellate cells through RORα-mediated inhibition of 5-lipoxygenase.
Shajari S, Laliena A, Heegsma J, Tuñón MJ, Moshage H, Faber KN.
J Pineal Res 59(3):391-401. doi: 10.1111/jpi.12271. Epub 2015 Sep 15. 2015
3ALOX5
The structure of human 5-lipoxygenase.
Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, Newcomer ME.
Science 331(6014):217-9. 2011
4ALOX5, COTL1
Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis.
Rådmark O, Samuelsson B.
Biochem Biophys Res Commun 396(1):105-10. Review. 2010
5ALOX5
Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.
Chen Y, Hu Y, Zhang H, Peng C, Li S.
Nat Genet 41(7):783-92. Epub 2009 Jun 7. 2009
6ALOX5, COTL1
Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.
Esser J, Rakonjac M, Hofmann B, Fischer L, Provost P, Schneider G, Steinhilber D, Samuelsson B, Rådmark O.
Biochem J 425(1):265-74.PMID: 19807693 2009
7ALOX5, ALOX5AP
Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease.
Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, Iribarren C, Boerwinkle E, Myers R, Risch N, Quertermous T.
Hum Genet 123(4):399-408. Epub 2008 Mar 28. 2008
8COTL1, ALOX5
Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production.
Rakonjac M, Fischer L, Provost P, Werz O, Steinhilber D, Samuelsson B, Radmark O.
Proc Natl Acad Sci U S A 103(35):13150-5. Epub 2006 Aug 21. 2006
9ALOX5, COTL1
Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production.
Rakonjac M, Fischer L, Provost P, Werz O, Steinhilber D, Samuelsson B, Rådmark O.
Proc Natl Acad Sci U S A 103(35):13150-5. Epub 2006 Aug 21.PMID: 16924104 2006
10ALOX5
Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.
Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M.
N Engl J Med 350(1):29-37. 2004
11ALOX5
Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase.
Kulkarni S, Das S, Funk CD, Murray D, Cho W.
J Biol Chem 277(15):13167-74. Epub 2002 Jan 16. 2002
12ALOX5
The N-terminal beta-barrel domain of 5-lipoxygenase is essential for nuclear membrane translocation.
Chen XS, Funk CD.
J Biol Chem 276(1):811-8. 2001
13ALOX5
Lipoxygenase-5 is overexpressed in prostate adenocarcinoma.
Gupta S, Srivastava M, Ahmad N, Sakamoto K, Bostwick DG, Mukhtar H.
Cancer 91(4):737-43. 2001
14ALOX5
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment.
Drazen JM, et al.
Nat Genet 22(2):168-70. 1999
15ALOX5
Localization of the gene for arachidonate 5-lipoxygenase.
Goodfellow PJ, et al.
Am J Hum Genet 51 : A396. 1992
16ALOX5
On the expression and regulation of 5-lipoxygenase in human lymphocytes.
Jakobsson PJ, et al.
Proc Natl Acad Sci U S A 89 : 3521-3525. 1992
17ALOX5
Characterization of the human 5-lipoxygenase gene.
Funk CD, et al.
Proc Natl Acad Sci U S A 86 : 2587-2591. 1989