| 1 | ADM, AGTRAP, ALOX5, ENTPD1, IRAK3, MMP9, S100A8
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| Identification of key pathogenic genes of sepsis based on the Gene Expression Omnibus database.
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| Lu X, Xue L, Sun W, Ye J, Zhu Z, Mei H.
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| Mol Med Rep. Feb;17(2):3042-3054. doi: 10.3892/mmr.2017.8258. Epub 2017 Dec 12 2018
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| 2 | ALOX5, RORA
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| Melatonin suppresses activation of hepatic stellate cells through RORα-mediated inhibition of 5-lipoxygenase.
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| Shajari S, Laliena A, Heegsma J, Tuñón MJ, Moshage H, Faber KN.
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| J Pineal Res 59(3):391-401. doi: 10.1111/jpi.12271. Epub 2015 Sep 15.
2015
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| 3 | ALOX5
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| The structure of human 5-lipoxygenase.
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| Gilbert NC, Bartlett SG, Waight MT, Neau DB, Boeglin WE, Brash AR, Newcomer ME.
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| Science 331(6014):217-9.
2011
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| 4 | ALOX5, COTL1
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| Regulation of the activity of 5-lipoxygenase, a key enzyme in leukotriene biosynthesis.
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| Rådmark O, Samuelsson B.
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| Biochem Biophys Res Commun 396(1):105-10. Review. 2010
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| 5 | ALOX5
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| Loss of the Alox5 gene impairs leukemia stem cells and prevents chronic myeloid leukemia.
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| Chen Y, Hu Y, Zhang H, Peng C, Li S.
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| Nat Genet 41(7):783-92. Epub 2009 Jun 7.
2009
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| 6 | ALOX5, COTL1
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| Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102.
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| Esser J, Rakonjac M, Hofmann B, Fischer L, Provost P, Schneider G, Steinhilber D, Samuelsson B, Rådmark O.
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| Biochem J 425(1):265-74.PMID: 19807693 2009
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| 7 | ALOX5, ALOX5AP
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| Common polymorphisms of ALOX5 and ALOX5AP and risk of coronary artery disease.
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| Assimes TL, Knowles JW, Priest JR, Basu A, Volcik KA, Southwick A, Tabor HK, Hartiala J, Allayee H, Grove ML, Tabibiazar R, Sidney S, Fortmann SP, Go A, Hlatky M, Iribarren C, Boerwinkle E, Myers R, Risch N, Quertermous T.
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| Hum Genet 123(4):399-408. Epub 2008 Mar 28. 2008
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| 8 | COTL1, ALOX5
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| Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production.
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| Rakonjac M, Fischer L, Provost P, Werz O, Steinhilber D, Samuelsson B, Radmark O.
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| Proc Natl Acad Sci U S A 103(35):13150-5. Epub 2006 Aug 21. 2006
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| 9 | ALOX5, COTL1
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| Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production.
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| Rakonjac M, Fischer L, Provost P, Werz O, Steinhilber D, Samuelsson B, Rådmark O.
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| Proc Natl Acad Sci U S A 103(35):13150-5. Epub 2006 Aug 21.PMID: 16924104 2006
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| 10 | ALOX5
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| Arachidonate 5-lipoxygenase promoter genotype, dietary arachidonic acid, and atherosclerosis.
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| Dwyer JH, Allayee H, Dwyer KM, Fan J, Wu H, Mar R, Lusis AJ, Mehrabian M.
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| N Engl J Med 350(1):29-37. 2004
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| 11 | ALOX5
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| Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase.
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| Kulkarni S, Das S, Funk CD, Murray D, Cho W.
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| J Biol Chem 277(15):13167-74. Epub 2002 Jan 16. 2002
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| 12 | ALOX5
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| The N-terminal beta-barrel domain of 5-lipoxygenase is essential for nuclear membrane translocation.
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| Chen XS, Funk CD.
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| J Biol Chem 276(1):811-8. 2001
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| 13 | ALOX5
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| Lipoxygenase-5 is overexpressed in prostate adenocarcinoma.
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| Gupta S, Srivastava M, Ahmad N, Sakamoto K, Bostwick DG, Mukhtar H.
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| Cancer 91(4):737-43. 2001
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| 14 | ALOX5
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| Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment.
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| Drazen JM, et al.
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| Nat Genet 22(2):168-70. 1999
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| 15 | ALOX5
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| Localization of the gene for arachidonate 5-lipoxygenase.
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| Goodfellow PJ, et al.
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| Am J Hum Genet 51 : A396. 1992
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| 16 | ALOX5
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| On the expression and regulation of 5-lipoxygenase in human lymphocytes.
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| Jakobsson PJ, et al.
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| Proc Natl Acad Sci U S A 89 : 3521-3525. 1992
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| 17 | ALOX5
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| Characterization of the human 5-lipoxygenase gene.
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| Funk CD, et al.
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| Proc Natl Acad Sci U S A 86 : 2587-2591. 1989
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