| 1 | ALOX15
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| Proinflammatory signaling in islet β cells propagates invasion of pathogenic immune cells in autoimmune diabetes.
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| Pińeros AR, Kulkarni A, Gao H, Orr KS, Glenn L, Huang F, Liu Y, Gannon M, Syed F, Wu W, Anderson CM, Evans-Molina C, McDuffie M, Nadler JL, Morris MA, Mirmira RG, Tersey SA.
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| Cell Rep. Jun 28;39(13):111011. doi: 10.1016/j.celrep.2022.111011. 2022
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| 2 | ALOX15, HNRNPK, RPS19
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| Methylated HNRNPK acts on RPS19 to regulate ALOX15 synthesis in erythropoiesis.
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| Naarmann-de Vries IS, Senatore R, Moritz B, Marx G, Urlaub H, Niessing D, Ostareck DH, Ostareck-Lederer A.
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| Nucleic Acids Res. Apr 6;49(6):3507-3523. doi: 10.1093/nar/gkab116. 2021
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| 3 | ALOX15
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| Arachidonic Acid 15-Lipoxygenase: Effects of Its Expression, Metabolites, and Genetic and Epigenetic Variations on Airway Inflammation
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| Xu X, Li J, Zhang Y, Zhang L.
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| Allergy Asthma Immunol Res. Sep;13(5):684-696. doi: 10.4168/aair.2021.13.5.684 2021
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| 4 | ALOX15
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| A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis
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| Kristjansson RP, Benonisdottir S, Davidsson OB, Oddsson A, Tragante V, Sigurdsson JK, Stefansdottir L, Jonsson S, Jensson BO, Arthur JG, Arnadottir GA, Sulem G, Halldorsson BV, Gunnarsson B, Halldorsson GH, Stefansson OA, Oskarsson GR, Deaton AM, Olafsson I, Eyjolfsson GI, Sigurdardottir O, Onundarson PT, Gislason D, Gislason T, Ludviksson BR, Ludviksdottir D, Olafsdottir TA, Rafnar T, Masson G, Zink F, Bjornsdottir G, Magnusson OT, Bjornsdottir US, Thorleifsson G, Norddahl GL, Gudbjartsson DF, Thorsteinsdottir U, Jonsdottir I, Sulem P, Stefansson K.
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| Nat Genet. Feb;51(2):267-276. doi: 10.1038/s41588-018-0314-6. Epub 2019 Jan 14. 2019
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| 5 | ALOX15, ALOX15B
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| Regulation and Functions of 15-Lipoxygenases in Human Macrophages
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| Snodgrass RG, Brüne B.
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| Front Pharmacol. Jul 4;10:719. doi: 10.3389/fphar.2019.00719. 2019
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| 6 | ALOX15
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| ALOX15 as a suppressor of inflammation and cancer: Lost in the link.
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| Tian R, Zuo X, Jaoude J, Mao F, Colby J, Shureiqi I.
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| Prostaglandins Other Lipid Mediat. Sep;132:77-83. doi: 10.1016/j.prostaglandins.2017.01.002. Epub 2017 Jan 13. 2017
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| 7 | ALOX15
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| Mammalian ALOX15 orthologs exhibit pronounced dual positional specificity with docosahexaenoic acid.
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| Kutzner L, Goloshchapova K, Heydeck D, Stehling S, Kuhn H, Schebb NH.
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| Biochim Biophys Acta Mol Cell Biol Lipids. 1862(7):666-675. doi: 10.1016/j.bbalip.2017.04.001. Epub 20 2017
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| 8 | ALOX15
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| The contribution of arachidonate 15-lipoxygenase in tissue macrophages to adipose tissue remodeling
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| Kwon HJ, Kim SN, Kim YA, Lee YH
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| Cell Death Dis. Jun 30;7(6):e2285. doi: 10.1038/cddis.2016.190 2016
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| 9 | ALOX15
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| Structural and functional biology of arachidonic acid 15-lipoxygenase-1 (ALOX15).
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| Ivanov I, Kuhn H, Heydeck D.
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| Gene. Nov 15;573(1):1-32. doi: 10.1016/j.gene.2015.07.073. Epub 2015 Jul 26. 2015
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| 10 | ALOX15
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| Polymorphisms in inflammation associated genes ALOX15 and IL-6 are associated with bone properties in young women and fracture in elderly
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| Herlin M, McGuigan FE, Luthman H, Ĺkesson K.
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| Bone Oct;79:105-9. doi: 10.1016/j.bone.2015.05.035. Epub 2015 May 30. 2015
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| 11 | ALOX15, VIM
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| Characterization of a human 12/15-lipoxygenase promoter variant associated with atherosclerosis identifies vimentin as a promoter binding protein.
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| Samanta S, Anderson K, Moran S, Hawke D, Gorenstein D, Fornage M.
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| PLoS One 7(8):e42417. doi: 10.1371/journal.pone.0042417. Epub 2012 Aug 7.
2012
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| 12 | ALOX15
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| Disruption of the 12/15-lipoxygenase gene (Alox15) protects hyperlipidemic mice from nonalcoholic fatty liver disease.
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| Martínez-Clemente M, Ferré N, Titos E, Horrillo R, González-Périz A, Morán-Salvador E, López-Vicario C, Miquel R, Arroyo V, Funk CD, Clŕria J.
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| Hepatology 52(6):1980-91. doi: 10.1002/hep.23928. Epub 2010 Oct 21.
2010
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| 13 | ALOX15
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| Monocyte 15-lipoxygenase gene expression requires ERK1/2 MAPK activity.
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| Bhattacharjee A, Mulya A, Pal S, Roy B, Feldman GM, Cathcart MK.
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| J Immunol 185(9):5211-24. Epub 2010 Sep 22.
2010
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| 14 | ALOX15
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| Two single nucleotide polymorphisms in ALOX15 are associated with risk of coronary artery disease in a Chinese Han population.
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| Zhang K, Wang YY, Liu QJ, Wang H, Liu FF, Ma ZY, Gong YQ, Li L.
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| Heart Vessels 25(5):368-73. Epub 2010 Jul 31.
2010
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| 15 | ALOX12, ALOX15
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| Hematopoietic stem cell function requires 12/15-lipoxygenase-dependent fatty acid metabolism.
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| Kinder M, Wei C, Shelat SG, Kundu M, Zhao L, Blair IA, Puré E.
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| Blood 115(24):5012-22. Epub 2010 Mar 31.
2010
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| 16 | ALOX12, ALOX15
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| 12/15-lipoxygenase is required for the early onset of high fat diet-induced adipose tissue inflammation and insulin resistance in mice.
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| Sears DD, Miles PD, Chapman J, Ofrecio JM, Almazan F, Thapar D, Miller YI.
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| PLoS One 4(9):e7250.
2009
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| 17 | ALOX12, ALOX15
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| Cardiac 12/15 lipoxygenase-induced inflammation is involved in heart failure.
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| Kayama Y, Minamino T, Toko H, Sakamoto M, Shimizu I, Takahashi H, Okada S, Tateno K, Moriya J, Yokoyama M, Nojima A, Yoshimura M, Egashira K, Aburatani H, Komuro I.
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| J Exp Med 206(7):1565-74. Epub 2009 Jun 22.
2009
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| 18 | ALOX15
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| 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA.
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| Jeon SG, Moon HG, Kim YS, Choi JP, Shin TS, Hong SW, Tae YM, Kim SH, Zhu Z, Gho YS, Kim YK.
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| Clin Exp Allergy 39(6):908-17. Epub 2009 Feb 25.
2009
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| 19 | ALOX15
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| 15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intima-media thickness.
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| McCaskie PA, Beilby JP, Hung J, Chapman CM, McQuillan BM, Powell BL, Thompson PL, Palmer LJ.
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| Hum Genet 123(5):445-53. Epub 2008 Apr 5. 2008
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| 20 | ALOX15
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| Hodgkin Reed-Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo: novel insight into the inflammatory features of classical Hodgkin lymphoma.
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| Claesson HE, Griffiths WJ, Brunnström A, Schain F, Andersson E, Feltenmark S, Johnson HA, Porwit A, Sjöberg J, Björkholm M.
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| FEBS J 275(16):4222-34. Epub 2008 Jul 18.
2008
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| 21 | ALOX15, SPI1
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| Functional polymorphism in ALOX15 results in increased allele-specific transcription in macrophages through binding of the transcription factor SPI1.
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| Wittwer J, Marti-Jaun J, Hersberger M.
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| Hum Mutat 27(1):78-87. 2006
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| 22 | HNRNPK, ALOX15
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| The DICE-binding activity of KH domain 3 of hnRNP K is affected by c-Src-mediated tyrosine phosphorylation.
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| Messias AC, Harnisch C, Ostareck-Lederer A, Sattler M, Ostareck DH.
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| J Mol Biol 361(3):470-81. Epub 2006 Jun 30. 2006
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| 23 | ALOX15
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| 15-lipoxygenase-1 overexpression in prostate adenocarcinoma.
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| Kelavkar U, Cohen C, Eling T, Badr K.
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| Adv Exp Med Biol 507:133-45. No abstract available. 2002
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| 24 | ALOX15
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| Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene.
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| Kelavkar UP, et al.
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| Proc Natl Acad Sci U S A 96(8):4378-83. 1999
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| 25 | ALOX15
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| Characterization and sequence of an additional 15-lipoxygenase transcript and of the human gene.
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| Kritzik MR, Ziober AF, Dicharry S, Conrad DJ, Sigal E.
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| Biochim Biophys Acta 1352(3):267-81. 1997
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| 26 | ALOX12, ALOX12P1, ALOX15
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| Characterization of human 12-lipoxygenase genes.
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| Funk CD, et al.
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| Proc Natl Acad Sci U S A 89 : 3962-3966. 1992
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