| 1 | ALKBH1, ALKBH2, ALKBH3, ALKBH5, ALKBH7, ALKBH8, FTO
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| The AlkB Family of Fe (II)/Alpha-Ketoglutarate-Dependent Dioxygenases Modulates Embryogenesis through Epigenetic Regulation.
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| Liu Y, Yuan Q, Xie L.
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| Curr Stem Cell Res Ther 13(2):136-143. doi: 10.2174/1574888X12666171027105532. Review.
2018
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| 2 | ALKBH1, ALKBH2, ALKBH3
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| Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA.
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| Westbye MP, Feyzi E, Aas PA, Vågbø CB, Talstad VA, Kavli B, Hagen L, Sundheim O, Akbari M, Liabakk NB, Slupphaug G, Otterlei M, Krokan HE.
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| J Biol Chem 283(36):25046-56. Epub 2008 Jul 3.
2008
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| 3 | ALKBH2, ALKBH3
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| Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA.
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| Ringvoll J, Nordstrand LM, Vagbo CB, Talstad V, Reite K, Aas PA, Lauritzen KH, Liabakk NB, Bjork A, Doughty RW, Falnes PO, Krokan HE, Klungland A.
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| EMBO J 25(10):2189-98. Epub 2006 Apr 27. 2006
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| 4 | ALKBH3
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| Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage.
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| Sundheim O, Vagbo CB, Bjoras M, Sousa MM, Talstad V, Aas PA, Drablos F, Krokan HE, Tainer JA, Slupphaug G.
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| EMBO J 25(14):3389-97. Epub 2006 Jul 6. 2006
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| 5 | ALKBH1, ALKBH2, ALKBH3
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| Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA.
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| Aas PA, Otterlei M, Falnes PO, Vagbo CB, Skorpen F, Akbari M, Sundheim O, Bjoras M, Slupphaug G, Seeberg E, Krokan HE.
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| Nature 421(6925):859-63. 2003
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| 6 | ALKBH2, ALKBH3
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| Reversal of DNA alkylation damage by two human dioxygenases.
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| Duncan T, Trewick SC, Koivisto P, Bates PA, Lindahl T, Sedgwick B.
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| Proc Natl Acad Sci U S A 99(26):16660-5. Epub 2002 Dec 16. 2002
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