Citations for
1AKR1C1, AKR1C4, AKR1D1
Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
Rižner TL, Penning TM.
Steroids 79:49-63. doi: 10.1016/j.steroids.2013.10.012. Epub 2013 Nov 1. Review. 2014
2AKR1D1, CBAS2
Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency.
Drury JE, Mindnich R, Penning TM.
J Biol Chem 285(32):24529-37. Epub 2010 Jun 3.PMID: 20522910 2010
3AKR1D1
Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex.
Drury JE, Di Costanzo L, Penning TM, Christianson DW.
J Biol Chem 284(30):19786-90. Epub 2009 Jun 10.PMID: 19515843 2009
4AKR1D1
Aldo-keto reductases in which the conserved catalytic histidine is substituted.
Di Costanzo L, Penning TM, Christianson DW.
Chem Biol Interact 178(1-3):127-33. Epub 2008 Nov 5.PMID: 19028475 2009
5AKR1D1
Structure and catalytic mechanism of human steroid 5beta-reductase (AKR1D1).
Di Costanzo L, Drury JE, Christianson DW, Penning TM.
Mol Cell Endocrinol 301(1-2):191-8. Epub 2008 Sep 19.PMID: 18848863 2009
6AKR1C4, AKR1D1
Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.
Lee WH, Lukacik P, Guo K, Ugochukwu E, Kavanagh KL, Marsden B, Oppermann U.
Mol Cell Endocrinol 301(1-2):199-204. doi: 10.1016/j.mce.2008.09.042. Epub 2008 Oct 22. 2009
7AKR1D1
Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition.
Faucher F, Cantin L, Luu-The V, Labrie F, Breton R.
Biochemistry 47(51):13537-46. Erratum in: Biochemistry. 2009 Feb 10;48(5):1144. PMID: 19075558 2008
8AKR1D1
Human Delta4-3-oxosteroid 5beta-reductase (AKR1D1) deficiency and steroid metabolism.
Palermo M, Marazzi MG, Hughes BA, Stewart PM, Clayton PT, Shackleton CH.
Steroids 73(4):417-23. Epub 2007 Dec 14.PMID: 18243262 2008
9AKR1D1
5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term.
Sheehan PM, Rice GE, Moses EK, Brennecke SP.
Mol Hum Reprod 11(7):495-501. 2005
10CBAS2, AKR1D1
Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy.
Lemonde HA, Custard EJ, Bouquet J, Duran M, Overmars H, Scambler PJ, Clayton PT.
Gut 52(10):1494-9. 2003
11AKR1D1, AKR1D1P
Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme.
Charbonneau A, The VL.
Biochim Biophys Acta 1517(2):228-35. 2001
12AKR1D1, AKR1D1P
Assignment of steroid 5beta-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32-->q33 and 1q23-->q25, respectively, byin situ hybridization.
Charbonneau A, et al.
Cytogenet Cell Genet 84(1-2):105-6. No abstract available 1999
13AKR1D1
Gene analysis in delta 4-3-oxosteroid 5 beta-reductase deficiency.
Sumazaki R, Nakamura N, Shoda J, Kurosawa T, Tohma M.
Lancet 349(9048):329. No abstract available. 1997
14AKR1D1
Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme.
Kondo KH, et al.
Eur J Biochem 219(1-2):357-63. 1994