1 | AKR1C1, AKR1C4, AKR1D1
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| Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
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| Rižner TL, Penning TM.
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| Steroids 79:49-63. doi: 10.1016/j.steroids.2013.10.012. Epub 2013 Nov 1. Review.
2014
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2 | AKR1D1, CBAS2
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| Characterization of disease-related 5beta-reductase (AKR1D1) mutations reveals their potential to cause bile acid deficiency.
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| Drury JE, Mindnich R, Penning TM.
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| J Biol Chem 285(32):24529-37. Epub 2010 Jun 3.PMID: 20522910 2010
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3 | AKR1D1
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| Inhibition of human steroid 5beta-reductase (AKR1D1) by finasteride and structure of the enzyme-inhibitor complex.
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| Drury JE, Di Costanzo L, Penning TM, Christianson DW.
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| J Biol Chem 284(30):19786-90. Epub 2009 Jun 10.PMID: 19515843 2009
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4 | AKR1D1
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| Aldo-keto reductases in which the conserved catalytic histidine is substituted.
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| Di Costanzo L, Penning TM, Christianson DW.
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| Chem Biol Interact 178(1-3):127-33. Epub 2008 Nov 5.PMID: 19028475 2009
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5 | AKR1D1
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| Structure and catalytic mechanism of human steroid 5beta-reductase (AKR1D1).
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| Di Costanzo L, Drury JE, Christianson DW, Penning TM.
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| Mol Cell Endocrinol 301(1-2):191-8. Epub 2008 Sep 19.PMID: 18848863 2009
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6 | AKR1C4, AKR1D1
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| Structure-activity relationships of human AKR-type oxidoreductases involved in bile acid synthesis: AKR1D1 and AKR1C4.
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| Lee WH, Lukacik P, Guo K, Ugochukwu E, Kavanagh KL, Marsden B, Oppermann U.
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| Mol Cell Endocrinol 301(1-2):199-204. doi: 10.1016/j.mce.2008.09.042. Epub 2008 Oct 22.
2009
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7 | AKR1D1
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| Crystal structures of human Delta4-3-ketosteroid 5beta-reductase (AKR1D1) reveal the presence of an alternative binding site responsible for substrate inhibition.
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| Faucher F, Cantin L, Luu-The V, Labrie F, Breton R.
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| Biochemistry 47(51):13537-46. Erratum in: Biochemistry. 2009 Feb 10;48(5):1144. PMID: 19075558 2008
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8 | AKR1D1
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| Human Delta4-3-oxosteroid 5beta-reductase (AKR1D1) deficiency and steroid metabolism.
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| Palermo M, Marazzi MG, Hughes BA, Stewart PM, Clayton PT, Shackleton CH.
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| Steroids 73(4):417-23. Epub 2007 Dec 14.PMID: 18243262 2008
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9 | AKR1D1
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| 5 Beta-dihydroprogesterone and steroid 5 beta-reductase decrease in association with human parturition at term.
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| Sheehan PM, Rice GE, Moses EK, Brennecke SP.
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| Mol Hum Reprod 11(7):495-501. 2005
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10 | CBAS2, AKR1D1
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| Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy.
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| Lemonde HA, Custard EJ, Bouquet J, Duran M, Overmars H, Scambler PJ, Clayton PT.
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| Gut 52(10):1494-9. 2003
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11 | AKR1D1, AKR1D1P
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| Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme.
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| Charbonneau A, The VL.
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| Biochim Biophys Acta 1517(2):228-35. 2001
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12 | AKR1D1, AKR1D1P
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| Assignment of steroid 5beta-reductase (SRD5B1) and its pseudogene (SRD5BP1) to human chromosome bands 7q32-->q33 and 1q23-->q25, respectively, byin situ hybridization.
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| Charbonneau A, et al.
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| Cytogenet Cell Genet 84(1-2):105-6. No abstract available 1999
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13 | AKR1D1
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| Gene analysis in delta 4-3-oxosteroid 5 beta-reductase deficiency.
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| Sumazaki R, Nakamura N, Shoda J, Kurosawa T, Tohma M.
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| Lancet 349(9048):329. No abstract available. 1997
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14 | AKR1D1
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| Cloning and expression of cDNA of human delta 4-3-oxosteroid 5 beta-reductase and substrate specificity of the expressed enzyme.
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| Kondo KH, et al.
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| Eur J Biochem 219(1-2):357-63. 1994
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