1 | AKR1C3, SIAH2
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| The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.
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| Fan L, Peng G, Hussain A, Fazli L, Guns E, Gleave M, Qi J.
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| J Biol Chem 290(34):20865-79. doi: 10.1074/jbc.M115.662155. Epub 2015 Jul 9.
2015
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2 | AKR1C1, AKR1C2, AKR1C3
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| Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
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| Hevir N, Vouk K, Sinkovec J, Ribič-Pucelj M, Rižner TL.
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| Chem Biol Interact 191(1-3):217-26. doi: 10.1016/j.cbi.2011.01.003. Epub 2011 Jan 11.
2011
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3 | AKR1C3
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| The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.
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| Birtwistle J, Hayden RE, Khanim FL, Green RM, Pearce C, Davies NJ, Wake N, Schrewe H, Ride JP, Chipman JK, Bunce CM.
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| Mutat Res 662(1-2):67-74. Epub 2008 Dec 31.
2009
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4 | AKR1C3, KLF15
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| KLF15 Is a transcriptional regulator of the human 17beta-hydroxysteroid dehydrogenase type 5 gene. A potential link between regulation of testosterone production and fat stores in women.
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| Du X, Rosenfield RL, Qin K.
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| J Clin Endocrinol Metab 94(7):2594-601. Epub 2009 Apr 14.
2009
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5 | AKR1C3
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| Regulation of human aldoketoreductase 1C3 (AKR1C3) gene expression in the adipose tissue.
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| Svensson PA, Gabrielsson BG, Jernås M, Gummesson A, Sjöholm K.
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| Cell Mol Biol Lett 13(4):599-613. Epub 2008 Jul 18.
2008
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6 | AKR1C3
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| Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system.
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| Azzarello J, Fung KM, Lin HK.
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| J Histochem Cytochem 56(9):853-61. Epub 2008 Jun 23.
2008
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7 | AKR1C3
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| Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
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| Figueroa JD, Malats N, García-Closas M, Real FX, Silverman D, Kogevinas M, Chanock S, Welch R, Dosemeci M, Lan Q, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Rothman N.
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| Carcinogenesis 29(10):1955-62. Epub 2008 Jul 16.
2008
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8 | AKR1C3, HSD17B1
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| Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5.
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| Lin SX, Shi R, Qiu W, Azzi A, Zhu DW, Dabbagh HA, Zhou M.
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| Mol Cell Endocrinol 248(1-2):38-46. Epub 2006 Feb 15. Review.
2006
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9 | AKR1C1, AKR1C2, AKR1C3
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| Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.
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| Lewis MJ, Wiebe JP, Heathcote JG.
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| BMC Cancer 4:27.
2004
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10 | AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@, AKRC@
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| Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
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| Penning TM, Burczynski ME, Jez JM, Hung CF, Lin HK, Ma H, Moore M, Palackal N, Ratnam K.
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| Biochem J 351(Pt 1):67-77. 2000
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11 | AKR1C3
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| Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase.
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| Dufort I, et al.
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| Endocrinology 140(2):568-74. 1999
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12 | AKR1C3
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| Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: Identification of a new syntenic relationship.
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| Rheault P, et al.
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| Cytogenet Cell Genet 84(3-4):241-242. No abstract available 1999
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13 | AKR1C3
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| Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity.
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| Matsuura K, et al.
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| J Biochem (Tokyo) 124(5):940-6. 1998
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14 | AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@
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| Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2)and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chainreaction and fluorescence in situ hybridization.
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| Khanna M, et al.
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| Genomics 25 : 588-590. 1995
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15 | AKR1C3, AKR1C4
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| Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.
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| Khanna M, et al.
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| J Biol Chem 270(34):20162-8. 1995
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16 | AKR1C1, AKR1C2, AKR1C3, AKR1C4
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| Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.
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| Qin KN, et al.
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| J Steroid Biochem Mol Biol 46(6):673-9. 1993
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