Citations for
1AKR1C3, SIAH2
The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.
Fan L, Peng G, Hussain A, Fazli L, Guns E, Gleave M, Qi J.
J Biol Chem 290(34):20865-79. doi: 10.1074/jbc.M115.662155. Epub 2015 Jul 9. 2015
2AKR1C1, AKR1C2, AKR1C3
Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
Hevir N, Vouk K, Sinkovec J, Ribič-Pucelj M, Rižner TL.
Chem Biol Interact 191(1-3):217-26. doi: 10.1016/j.cbi.2011.01.003. Epub 2011 Jan 11. 2011
3AKR1C3
The aldo-keto reductase AKR1C3 contributes to 7,12-dimethylbenz(a)anthracene-3,4-dihydrodiol mediated oxidative DNA damage in myeloid cells: implications for leukemogenesis.
Birtwistle J, Hayden RE, Khanim FL, Green RM, Pearce C, Davies NJ, Wake N, Schrewe H, Ride JP, Chipman JK, Bunce CM.
Mutat Res 662(1-2):67-74. Epub 2008 Dec 31. 2009
4AKR1C3, KLF15
KLF15 Is a transcriptional regulator of the human 17beta-hydroxysteroid dehydrogenase type 5 gene. A potential link between regulation of testosterone production and fat stores in women.
Du X, Rosenfield RL, Qin K.
J Clin Endocrinol Metab 94(7):2594-601. Epub 2009 Apr 14. 2009
5AKR1C3
Regulation of human aldoketoreductase 1C3 (AKR1C3) gene expression in the adipose tissue.
Svensson PA, Gabrielsson BG, Jernås M, Gummesson A, Sjöholm K.
Cell Mol Biol Lett 13(4):599-613. Epub 2008 Jul 18. 2008
6AKR1C3
Tissue distribution of human AKR1C3 and rat homolog in the adult genitourinary system.
Azzarello J, Fung KM, Lin HK.
J Histochem Cytochem 56(9):853-61. Epub 2008 Jun 23. 2008
7AKR1C3
Bladder cancer risk and genetic variation in AKR1C3 and other metabolizing genes.
Figueroa JD, Malats N, García-Closas M, Real FX, Silverman D, Kogevinas M, Chanock S, Welch R, Dosemeci M, Lan Q, Tardón A, Serra C, Carrato A, García-Closas R, Castaño-Vinyals G, Rothman N.
Carcinogenesis 29(10):1955-62. Epub 2008 Jul 16. 2008
8AKR1C3, HSD17B1
Structural basis of the multispecificity demonstrated by 17beta-hydroxysteroid dehydrogenase types 1 and 5.
Lin SX, Shi R, Qiu W, Azzi A, Zhu DW, Dabbagh HA, Zhou M.
Mol Cell Endocrinol 248(1-2):38-46. Epub 2006 Feb 15. Review. 2006
9AKR1C1, AKR1C2, AKR1C3
Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.
Lewis MJ, Wiebe JP, Heathcote JG.
BMC Cancer 4:27. 2004
10AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@, AKRC@
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
Penning TM, Burczynski ME, Jez JM, Hung CF, Lin HK, Ma H, Moore M, Palackal N, Ratnam K.
Biochem J 351(Pt 1):67-77. 2000
11AKR1C3
Characteristics of a highly labile human type 5 17beta-hydroxysteroid dehydrogenase.
Dufort I, et al.
Endocrinology 140(2):568-74. 1999
12AKR1C3
Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: Identification of a new syntenic relationship.
Rheault P, et al.
Cytogenet Cell Genet 84(3-4):241-242. No abstract available 1999
13AKR1C3
Identification of a principal mRNA species for human 3alpha-hydroxysteroid dehydrogenase isoform (AKR1C3) that exhibits high prostaglandin D2 11-ketoreductase activity.
Matsuura K, et al.
J Biochem (Tokyo) 124(5):940-6. 1998
14AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@
Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2)and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chainreaction and fluorescence in situ hybridization.
Khanna M, et al.
Genomics 25 : 588-590. 1995
15AKR1C3, AKR1C4
Substrate specificity, gene structure, and tissue-specific distribution of multiple human 3 alpha-hydroxysteroid dehydrogenases.
Khanna M, et al.
J Biol Chem 270(34):20162-8. 1995
16AKR1C1, AKR1C2, AKR1C3, AKR1C4
Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.
Qin KN, et al.
J Steroid Biochem Mol Biol 46(6):673-9. 1993