| 1 | AKR1C1, AKR1C2, AKR1C4
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| Long-chain fatty acids inhibit human members of the aldo-keto reductase 1C subfamily.
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| Hara A, Endo S, Matsunaga T, Soda M, Yashiro K, El-Kabbani O.
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| J Biochem 162(5):371-379. doi: 10.1093/jb/mvx041.
2017
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| 2 | AKR1C1
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| High expression of AKR1C1 is associated with proliferation and migration of small-cell lung cancer cells.
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| Tian H, Li X, Jiang W, Lv C, Sun W, Huang C, Chen R.
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| Lung Cancer (Auckl) 7:53-61. doi: 10.2147/LCTT.S90694. eCollection 2016.
2016
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| 3 | AKR1C1
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| Aldo-keto reductase 1C1 induced by interleukin-1β mediates the invasive potential and drug resistance of metastatic bladder cancer cells.
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| Matsumoto R, Tsuda M, Yoshida K, Tanino M, Kimura T, Nishihara H, Abe T, Shinohara N, Nonomura K, Tanaka S.
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| Sci Rep 6:34625. doi: 10.1038/srep34625.
2016
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| 4 | AKR1C1, AKR1C4, AKR1D1
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| Role of aldo-keto reductase family 1 (AKR1) enzymes in human steroid metabolism.
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| Rižner TL, Penning TM.
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| Steroids 79:49-63. doi: 10.1016/j.steroids.2013.10.012. Epub 2013 Nov 1. Review.
2014
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| 5 | AKR1C1, AKR1C2, IL1B
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| Interleukin 1β regulates progesterone metabolism in human cervical fibroblasts.
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| Roberson AE, Hyatt K, Kenkel C, Hanson K, Myers DA.
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| Reprod Sci 19(3):271-81. doi: 10.1177/1933719111419246. Epub 2011 Nov 7. Erratum in: Reprod Sci. 2012 Jun;19(6):666.
2012
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| 6 | AKR1C1, AKR1C2, AKR1C3
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| Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
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| Hevir N, Vouk K, Sinkovec J, Ribič-Pucelj M, Rižner TL.
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| Chem Biol Interact 191(1-3):217-26. doi: 10.1016/j.cbi.2011.01.003. Epub 2011 Jan 11.
2011
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| 7 | AKR1C1, AKR1C4
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| Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.
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| Jin Y, Mesaros AC, Blair IA, Penning TM.
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| Biochem J 437(1):53-61. doi: 10.1042/BJ20101804.
2011
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| 8 | AKR1C1, AKR1C2
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| Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.
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| Marín YE, Seiberg M, Lin CB.
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| Exp Dermatol 18(7):611-8. doi: 10.1111/j.1600-0625.2008.00839.x. Epub 2009 Mar 6.
2009
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| 9 | AKR1C1, AKR1C2, AKR1C3
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| Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.
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| Lewis MJ, Wiebe JP, Heathcote JG.
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| BMC Cancer 4:27.
2004
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| 10 | AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@, AKRC@
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| Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
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| Penning TM, Burczynski ME, Jez JM, Hung CF, Lin HK, Ma H, Moore M, Palackal N, Ratnam K.
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| Biochem J 351(Pt 1):67-77. 2000
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| 11 | AKR1C1, AKR1C@
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| Cloning and sequencing of the cDNA species for mammalian dimeric dihydrodiol dehydrogenases.
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| Arimitsu E, Aoki S, Ishikura S, Nakanishi K, Matsuura K, Hara A.
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| Biochem J 342 Pt 3:721-8 1999
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| 12 | AKR1A1, AKR1B1, AKR1C1, AKR1C4, AKR1C@, AKR7A2
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| Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.
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| O'connor T, Ireland LS, Harrison DJ, Hayes JD.
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| Biochem J 343 Pt 2:487-504 1999
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| 13 | AKR1C1, AKR1C2, AKR1C3, AKR1C4, AKR1C@
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| Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2)and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chainreaction and fluorescence in situ hybridization.
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| Khanna M, et al.
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| Genomics 25 : 588-590. 1995
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| 14 | AKR1C1
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| Genomic organization and chromosomal localization of a novel human hepatic dihydrodiol dehydrogenase with high affinity bile acid binding.
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| Lou H, et al.
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| J Biol Chem 269 : 8416-8422. 1994
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| 15 | AKR1C1
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| cDNA cloning and expression of the human hepatic bile acid-binding protein.
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| Stolz A, et al.
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| J Biol Chem 268 : 10448-10457. 1993
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| 16 | AKR1C1, AKR1C2, AKR1C3, AKR1C4
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| Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.
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| Qin KN, et al.
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| J Steroid Biochem Mol Biol 46(6):673-9. 1993
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