1 | AKR1B1
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| The human aldose reductase AKR1B1 qualifies as the primary prostaglandin F synthase in the endometrium.
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| Bresson E, Boucher-Kovalik S, Chapdelaine P, Madore E, Harvey N, Laberge PY, Leboeuf M, Fortier MA.
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| J Clin Endocrinol Metab 96(1):210-9. Epub 2010 Oct 13.
2011
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2 | AKR1B1
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| More severe type 2 diabetes-associated ischemic stroke injury is alleviated in aldose reductase-deficient mice.
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| Yeung CM, Lo AC, Cheung AK, Chung SS, Wong D, Chung SK.
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| J Neurosci Res 88(9):2026-34.
2010
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3 | AKR1B1
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| Aldose reductase regulates vascular smooth muscle cell proliferation by modulating G1/S phase transition of cell cycle.
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| Tammali R, Saxena A, Srivastava SK, Ramana KV.
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| Endocrinology 151(5):2140-50. Epub 2010 Mar 22.
2010
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4 | AKR1B1
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| Aldose reductase is a potent regulator of TGF-β1 induced expression of fibronectin in human mesangial cells.
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| Huang P, Zhang Y, Jiang T, Zeng W, Zhang N.
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| Mol Biol Rep 37(7):3097-103. Epub 2009 Oct 22.
2010
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5 | AKR1B1
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| Regulation of AKR1B1 by thyroid hormone and its receptors.
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| Liao CS, Tai PJ, Huang YH, Chen RN, Wu SM, Kuo LW, Yeh CT, Tsai MM, Chen WJ, Lin KH.
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| Mol Cell Endocrinol 307(1-2):109-17. Epub 2009 May 5.
2009
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6 | AKR1B1
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| Merging the binding sites of aldose and aldehyde reductase for detection of inhibitor selectivity-determining features.
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| Steuber H, Heine A, Podjarny A, Klebe G.
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| J Mol Biol 379(5):991-1016. Epub 2008 Apr 8.
2008
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7 | AKR1B1
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| Aldose reductase regulates hepatic peroxisome proliferator-activated receptor alpha phosphorylation and activity to impact lipid homeostasis.
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| Qiu L, Wu X, Chau JF, Szeto IY, Tam WY, Guo Z, Chung SK, Oates PJ, Chung SS, Yang JY.
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| J Biol Chem 283(25):17175-83. Epub 2008 Apr 29.
2008
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8 | AKR1B1
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| Evidence for a novel binding site conformer of aldose reductase in ligand-bound state.
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| Steuber H, Zentgraf M, La Motta C, Sartini S, Heine A, Klebe G.
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| J Mol Biol 369(1):186-97. Epub 2007 Mar 15.
2007
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9 | AKR1B1
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| Endotoxin-induced cardiomyopathy and systemic inflammation in mice is prevented by aldose reductase inhibition.
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| Ramana KV, Willis MS, White MD, Horton JW, DiMaio JM, Srivastava D, Bhatnagar A, Srivastava SK.
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| Circulation 114(17):1838-46. Epub 2006 Oct 9.
2006
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10 | AKR1B1
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| C(-106)T polymorphism of the aldose reductase gene and the progression rate of diabetic retinopathy.
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| Olmos P, Bastías MJ, Vollrath V, Toro L, Trincado A, Salinas P, Claro JC, López JM, Acosta AM, Miquel JF, Castro J.
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| Diabetes Res Clin Pract 74(2):175-82. Epub 2006 May 15.
2006
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11 | AKR1B1
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| Aldose reductase (AC)n gene polymorphism and susceptibility to diabetic retinopathy in Type 2 diabetes in Caucasians.
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| Petrovic MG, Peterlin B, Hawlina M, Petrovic D.
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| J Diabetes Complications 19(2):70-3.
2005
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12 | AKR1B1
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| Inhibition of aldose reductase attenuates TNF-alpha-induced expression of adhesion molecules in endothelial cells.
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| Ramana KV, Bhatnagar A, Srivastava SK.
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| FASEB J 18(11):1209-18.
2004
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13 | AKR1B1
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| Aldose reductase regulates TNF-alpha-induced cell signaling and apoptosis in vascular endothelial cells.
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| Ramana KV, Bhatnagar A, Srivastava SK.
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| FEBS Lett 570(1-3):189-94.
2004
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14 | AKR1B1
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| The role of aldose reductase gene in the susceptibility to diabetic nephropathy in Type II (non-insulin-dependent) diabetes mellitus.
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| Moczulski DK, et al.
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| Diabetologia 42(1):94-7. 1999
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15 | AKR1A1, AKR1B1, AKR1C1, AKR1C4, AKR1C@, AKR7A2
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| Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members.
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| O'connor T, Ireland LS, Harrison DJ, Hayes JD.
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| Biochem J 343 Pt 2:487-504 1999
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16 | AKR1B1, AKR1B1P1, AKR1B1P2, AKR1B1P3, AKR1B1P4, AKR1B1P5, ALDRL2
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| Mapping of aldose reductase gene sequences to human chromosomes 1, 3, 7, 9, 11 and 13.
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| Bateman JB, et al.
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| Genomics 17 : 560-565. 1993
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17 | AKR1A1, AKR1B1
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| The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases.
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| Bohren KM, Bullock B, Wermuth B, Gabbay KH.
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| J Biol Chem 264(16):9547-51 1989
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