1 | AHR, RP85
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| A splicing mutation in aryl hydrocarbon receptor associated with retinitis pigmentosa
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| Zhou Y, Li S, Huang L, Yang Y, Zhang L, Yang M, Liu W, Ramasamy K, Jiang Z, Sundaresan P, Zhu X, Yang Z
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| Hum Mol Genet. Jul 15;27(14):2563-2572. doi: 10.1093/hmg/ddy165. Erratum in: Hum Mol Genet. 2018 Jul 15;27(14):2587 2018
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2 | AHR
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| Control of immune-mediated pathology via the aryl hydrocarbon receptor.
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| Wheeler MA, Rothhammer V, Quintana FJ.
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| J Biol Chem Biol Chem. 2017 Jun 14. pii: jbc.R116.767723. doi: 10.1074/jbc.R116.767723. [Epub ahead of print]
2017
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3 | AHR
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| Structural Basis for Aryl Hydrocarbon Receptor-Mediated Gene Activation.
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| Schulte KW, Green E, Wilz A, Platten M, Daumke O.
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| Structure tructure. 2017 May 30. pii: S0969-2126(17)30142-9. doi: 10.1016/j.str.2017.05.008. [Epub ahead of print]
2017
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4 | AHR
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| Aryl hydrocarbon receptor inhibition promotes hemato-lymphoid development from human pluripotent stem cells.
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| Angelos MG, Ruh PN, Webber BR, Blum RH, Ryan CD, Bendzick L, Shim S, Yingst AM, Tufa DM, Verneris MR, Kaufman DS.
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| Blood lood. 2017 May 22. pii: blood-2016-07-730440. doi: 10.1182/blood-2016-07-730440. [Epub ahead of print]
2017
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5 | AHR
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| Aryl hydrocarbon receptor and unexplained miscarriage.
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| Fan H, Su X, Yang B, Zhao A.
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| J Obstet Gynaecol Res 43(6):1029-1036. doi: 10.1111/jog.13309. Epub 2017 May 15.
2017
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6 | AHR, ARNT
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| A Molecular Mechanism To Switch the Aryl Hydrocarbon Receptor from a Transcription Factor to an E3 Ubiquitin Ligase.
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| Luecke-Johansson S, Gralla M, Rundqvist H, Ho JC, Johnson RS, Gradin K, Poellinger L.
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| Mol Cell Biol 37(13). pii: e00630-16. doi: 10.1128/MCB.00630-16. Print 2017 Jul 1.
2017
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7 | AHR
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| Aryl Hydrocarbon Receptor Deficiency Alters Circadian and Metabolic Rhythmicity.
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| Jaeger C, Khazaal AQ, Xu C, Sun M, Krager SL, Tischkau SA.
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| J Biol Rhythms 32(2):109-120. doi: 10.1177/0748730417696786. Epub 2017 Mar 27.
2017
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8 | AHR
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| Cell and region specificity of Aryl hydrocarbon Receptor (AhR) system in the testis and the epididymis.
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| Wajda A, Łapczuk J, Grabowska M, Pius-Sadowska E, Słojewski M, Laszczynska M, Urasinska E, Machalinski B, Drozdzik M.
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| Reprod Toxicol 69:286-296. doi: 10.1016/j.reprotox.2017.03.009. Epub 2017 Mar 21.
2017
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9 | AHR
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| Feedback control of AHR signalling regulates intestinal immunity.
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| Schiering C, Wincent E, Metidji A, Iseppon A, Li Y, Potocnik AJ, Omenetti S, Henderson CJ, Wolf CR, Nebert DW, Stockinger B.
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| Nature 542(7640):242-245. doi: 10.1038/nature21080. Epub 2017 Feb 1.
2017
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10 | AHR
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| Aryl hydrocarbon receptor is required for optimal B-cell proliferation.
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| Villa M, Gialitakis M, Tolaini M, Ahlfors H, Henderson CJ, Wolf CR, Brink R, Stockinger B.
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| EMBO J 36(1):116-128. doi: 10.15252/embj.201695027. Epub 2016 Nov 14.
2017
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11 | AHR, CYP3A4, NR1I2
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| Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
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| Rasmussen MK, Daujat-Chavanieu M, Gerbal-Chaloin S.
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| Toxicol Lett 277:1-8. doi: 10.1016/j.toxlet.2017.05.029. Epub 2017 May 29.
2017
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12 | AHR, DLX3
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| Transcription factor Dlx3 induces aryl hydrocarbon receptor promoter activity.
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| Shin JH, Haggadone MD, Sunwoo JB.
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| Biochem Biophys Rep 7:353-360.
2016
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13 | AHR
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| Antioxidant Functions of the Aryl Hydrocarbon Receptor.
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| Dietrich C.
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| Stem Cells Int 2016:7943495. Epub 2016 Oct 18. Review.
2016
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14 | AHR
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| The aryl hydrocarbon receptor is required for the maintenance of liver-resident natural killer cells.
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| Zhang LH, Shin JH, Haggadone MD, Sunwoo JB.
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| J Exp Med 213(11):2249-2257. Epub 2016 Sep 26.
2016
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15 | AHR
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| Aryl Hydrocarbon Receptor in Keratinocytes Is Essential for Murine Skin Barrier Integrity.
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| Haas K, Weighardt H, Deenen R, Köhrer K, Clausen B, Zahner S, Boukamp P, Bloch W, Krutmann J, Esser C.
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| J Invest Dermatol 136(11):2260-2269. doi: 10.1016/j.jid.2016.06.627. Epub 2016 Jul 16.
2016
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16 | AHR
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| Repression of the Aryl Hydrocarbon Receptor Is Required to Maintain Mitotic Progression and Prevent Loss of Pluripotency of Embryonic Stem Cells.
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| Ko CI, Fan Y, de Gannes M, Wang Q, Xia Y, Puga A.
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| Stem Cells 34(12):2825-2839. doi: 10.1002/stem.2456. Epub 2016 Jul 15.
2016
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17 | AHR
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| Aryl hydrocarbon receptor influences nitric oxide and arginine production and alters M1/M2 macrophage polarization.
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| Climaco-Arvizu S, Domínguez-Acosta O, Cabañas-Cortés MA, Rodríguez-Sosa M, Gonzalez FJ, Vega L, Elizondo G.
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| Life Sci 155:76-84. doi: 10.1016/j.lfs.2016.05.001. Epub 2016 May 3.
2016
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18 | AHR, SMARCA4
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| Regulation of aryl hydrocarbon receptor-mediated transcription in human retinal pigmented epithelial cells.
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| Jin HL, Jeong KW.
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| Biochem Biophys Res Commun 472(2):366-72. doi: 10.1016/j.bbrc.2016.03.006. Epub 2016 Mar 7.
2016
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19 | AHR
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| AHR Function in Lymphocytes: Emerging Concepts.
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| Zhou L.
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| Trends Immunol 37(1):17-31. doi: 10.1016/j.it.2015.11.007. Epub 2015 Dec 11. Review.
2016
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20 | AHR, AIP
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| AIP mutations impair AhR signaling in pituitary adenoma patients fibroblasts and in GH3 cells.
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| Lecoq AL, Viengchareun S, Hage M, Bouligand J, Young J, Boutron A, Zizzari P, Lombès M, Chanson P, Kamenický P.
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| Endocr Relat Cancer 23(5):433-43. doi: 10.1530/ERC-16-0041. Epub 2016 Apr 14.
2016
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21 | AHR, ARNT, ARNT2, MAGED1, SIM1, SIM2
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| MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.
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| Sullivan AE, Peet DJ, Whitelaw ML.
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| FEBS J 283(18):3488-502. doi: 10.1111/febs.13824. Epub 2016 Aug 18.
2016
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22 | AHR
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| Activation of AHR mediates the ubiquitination and proteasome degradation of c-Fos through the induction of Ubcm4 gene expression.
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| Mejía-García A, González-Barbosa E, Martínez-Guzmán C, Torres-Ramos MA, Rodríguez MS, Guzmán-León S, Elizondo G.
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| Toxicology 337:47-57. doi: 10.1016/j.tox.2015.08.008. Epub 2015 Aug 28.
2015
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23 | AHR
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| Gene regulation of filaggrin and other skin barrier proteins via aryl hydrocarbon receptor.
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| Furue M, Tsuji G, Mitoma C, Nakahara T, Chiba T, Morino-Koga S, Uchi H.
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| J Dermatol Sci 80(2):83-8. doi: 10.1016/j.jdermsci.2015.07.011. Epub 2015 Jul 26. Review.
2015
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24 | AHR
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| Control of lymphocyte homeostasis and effector function by the aryl hydrocarbon receptor.
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| Wang H, Wei Y, Yu D.
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| Int Immunopharmacol 28(2):818-24. doi: 10.1016/j.intimp.2015.03.046. Epub 2015 Apr 20. Review.
2015
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25 | AHR
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| Aryl hydrocarbon receptors in osteoclast lineage cells are a negative regulator of bone mass.
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| Yu TY, Pang WJ, Yang GS.
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| PLoS One 10(1):e0117112. doi: 10.1371/journal.pone.0117112. eCollection 2015.
2015
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26 | AHR, NCOA2
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| NcoA2-Dependent Inhibition of HIF-1α Activation Is Regulated via AhR.
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| Tsai CH, Li CH, Liao PL, Cheng YW, Lin CH, Huang SH, Kang JJ.
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| Toxicol Sci 148(2):517-30. doi: 10.1093/toxsci/kfv199. Epub 2015 Sep 8.
2015
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27 | AHR, LHCGR
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| Transcriptional repression of the Ahr gene by LHCGR signaling in preovulatory granulosa cells is controlled by chromatin accessibility.
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| Teino I, Matvere A, Kuuse S, Ingerpuu S, Maimets T, Kristjuhan A, Tiido T.
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| Mol Cell Endocrinol 382(1):292-301. doi: 10.1016/j.mce.2013.10.011. Epub 2013 Oct 18.
2014
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28 | AHR, IDO1
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| Aryl hydrocarbon receptor and kynurenine: recent advances in autoimmune disease research.
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| Nguyen NT, Nakahama T, Le DH, Van Son L, Chu HH, Kishimoto T.
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| Front Immunol 5:551. doi: 10.3389/fimmu.2014.00551. eCollection 2014. Review.
2014
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29 | AHR, HSP90AA1
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| The activation mechanism of the aryl hydrocarbon receptor (AhR) by molecular chaperone HSP90.
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| Tsuji N, Fukuda K, Nagata Y, Okada H, Haga A, Hatakeyama S, Yoshida S, Okamoto T, Hosaka M, Sekine K, Ohtaka K, Yamamoto S, Otaka M, Grave E, Itoh H.
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| FEBS Open Bio 4:796-803. doi: 10.1016/j.fob.2014.09.003. eCollection 2014.
2014
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30 | AHR
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| The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway.
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| Yu H, Du Y, Zhang X, Sun Y, Li S, Dou Y, Li Z, Yuan H, Zhao W.
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| Toxicol Appl Pharmacol 280(3):502-10. doi: 10.1016/j.taap.2014.08.025. Epub 2014 Sep 3.
2014
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31 | AHR, MT2A
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| The aryl hydrocarbon receptor and glucocorticoid receptor interact to activate human metallothionein 2A.
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| Sato S, Shirakawa H, Tomita S, Tohkin M, Gonzalez FJ, Komai M.
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| Toxicol Appl Pharmacol 273(1):90-9. doi: 10.1016/j.taap.2013.08.017. Epub 2013 Aug 28.
2013
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32 | AHR, STC2
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| Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target gene.
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| Harper TA Jr, Joshi AD, Elferink CJ.
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| J Pharmacol Exp Ther 344(3):579-88. doi: 10.1124/jpet.112.201111. Epub 2012 Dec 26.
2013
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33 | AHR, NFIC
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| Inhibition of AHR transcription by NF1C is affected by a single-nucleotide polymorphism, and is involved in suppression of human uterine endometrial cancer
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| Li D, Takao T, Tsunematsu R, Morokuma S, Fukushima K, Kobayashi H, Saito T, Furue M, Wake N, Asanoma K.
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| Oncogene. Oct 10;32(41):4950-9. doi: 10.1038/onc.2012.509. Epub 2012 Dec 3. 2013
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34 | AHR, CCNG2, FOXA1
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| FOXA1 is essential for aryl hydrocarbon receptor-dependent regulation of cyclin G2.
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| Ahmed S, Al-Saigh S, Matthews J.
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| Mol Cancer Res 10(5):636-48.
2012
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35 | AHR, VAV3
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| Transcriptional factor aryl hydrocarbon receptor (Ahr) controls cardiovascular and respiratory functions by regulating the expression of the Vav3 proto-oncogene.
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| Sauzeau V, Carvajal-González JM, Riolobos AS, Sevilla MA, Menacho-Márquez M, Román AC, Abad A, Montero MJ, Fernández-Salguero P, Bustelo XR.
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| J Biol Chem 286(4):2896-909. doi: 10.1074/jbc.M110.187534. Epub 2010 Nov 29.
2011
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36 | AHR, MAF
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| The aryl hydrocarbon receptor interacts with c-Maf to promote the differentiation of type 1 regulatory T cells induced by IL-27.
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| Apetoh L, Quintana FJ, Pot C, Joller N, Xiao S, Kumar D, Burns EJ, Sherr DH, Weiner HL, Kuchroo VK.
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| Nat Immunol 11(9):854-61. Epub 2010 Aug 1.
2010
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37 | AHR, AIP
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| The aryl hydrocarbon receptor-interacting protein (AIP) is required for dioxin-induced hepatotoxicity but not for the induction of the Cyp1a1 and Cyp1a2 genes.
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| Nukaya M, Lin BC, Glover E, Moran SM, Kennedy GD, Bradfield CA.
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| J Biol Chem 285(46):35599-605. doi: 10.1074/jbc.M110.132043. Epub 2010 Sep 9.
2010
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38 | AHR, CA9
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| Role of aryl hydrocarbon receptor in modulation of the expression of the hypoxia marker carbonic anhydrase IX.
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| Takacova M, Holotnakova T, Vondracek J, Machala M, Pencikova K, Gradin K, Poellinger L, Pastorek J, Pastorekova S, Kopacek J.
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| Biochem J 419(2):419-25.
2009
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39 | AHR
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| Repression of aryl hydrocarbon receptor transcriptional activity by epidermal growth factor.
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| Hankinson O.
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| Mol Interv 9(3):116-8.PMID: 19592671 2009
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40 | AHR
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| Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells.
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| Platzer B, Richter S, Kneidinger D, Waltenberger D, Woisetschläger M, Strobl H.
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| J Immunol 183(1):66-74. Epub 2009 Jun 17.PMID: 19535631 2009
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41 | AHR, UGT1A3
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| Aryl hydrocarbon receptor-mediated regulation of the human estrogen and bile acid UDP-glucuronosyltransferase 1A3 gene.
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| Lankisch TO, Gillman TC, Erichsen TJ, Ehmer U, Kalthoff S, Freiberg N, Munzel PA, Manns MP, Strassburg CP.
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| Arch Toxicol 82(9):573-82. Epub 2008 Aug 2. 2008
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42 | AHR, E2F1
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| The aryl hydrocarbon receptor binds to E2F1 and inhibits E2F1-induced apoptosis.
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| Marlowe JL, Fan Y, Chang X, Peng L, Knudsen ES, Xia Y, Puga A.
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| Mol Biol Cell 19(8):3263-71. Epub 2008 Jun 4.PMID: 18524851 2008
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43 | AHR, IGFBP1, LPL
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| Regulation of insulin-like growth factor binding protein-1 and lipoprotein lipase by the aryl hydrocarbon receptor.
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| Minami K, Nakajima M, Fujiki Y, Katoh M, Gonzalez FJ, Yokoi T.
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| J Toxicol Sci 33(4):405-13.
2008
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44 | AHR, NFE2L2
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| NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis.
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| Shin S, Wakabayashi N, Misra V, Biswal S, Lee GH, Agoston ES, Yamamoto M, Kensler TW.
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| Mol Cell Biol 27(20):7188-97. Epub 2007 Aug 20.PMID: 17709388 2007
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45 | AHR, SNAI2
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| Zinc finger transcription factor Slug is a novel target gene of aryl hydrocarbon receptor.
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| Ikuta T, Kawajiri K.
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| Exp Cell Res 312(18):3585-94. Epub 2006 Aug 9. 2006
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46 | AHR, NCOA4
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| Functional interaction of nuclear receptor coactivator 4 with aryl hydrocarbon receptor.
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| Kollara A, Brown TJ.
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| Biochem Biophys Res Commun 346(2):526-34. Epub 2006 Jun 2.
2006
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47 | AHR
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| Molecular mechanisms of AhR functions in the regulation of cytochrome P450 genes.
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| Fujii-Kuriyama Y, Mimura J.
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| Biochem Biophys Res Commun 338(1):311-7. Epub 2005 Aug 30. Review. 2005
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48 | AHR
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| Single nucleotide polymorphism analysis and functional characterization of the human Ah receptor (AhR) gene promoter.
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| Racky J, Schmitz HJ, Kauffmann HM, Schrenk D.
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| Arch Biochem Biophys 421(1):91-8. 2004
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49 | AHR
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| The aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT) heterodimer interacts with naturally occurring estrogen response elements.
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| Klinge CM, Bowers JL, Kulakosky PC, Kamboj KK, Swanson HI.
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| Mol Cell Endocrinol 157(1-2):105-19. 1999
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50 | AHR, AIP
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| Characterization of the Ah receptor-associated protein, ARA9.
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| Carver LA, et al.
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| J Biol Chem 273 : 33580-33587. 1998
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51 | AHR, RB1
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| A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle.
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| Ge NL, Elferink CJ.
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| J Biol Chem 273(35):22708-13. 1998
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52 | AHR
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| Chromosomal localization of the human AHR locus encoding the structural gene for the Ah receptor to 7p21-p15.
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| Le Beau MM, et al.
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| Cytogenet Cell Genet 66 : 172-176. 1994
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53 | AHR
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| An Mspl RFLP of the human AHR gene.
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| Jones JE, et al.
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| Hum Mol Genet 3 : 2083. 1994
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54 | AHR
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| Human arylhydrocarbon receptor : functional expression and chromosomal assignment to 7p21.
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| Ema M, et al.
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| J Biochem 116 : 845-851. 1994
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55 | AHR
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| Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor.
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| Burbach KM, et al.
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| Proc Natl Acad Sci U S A 89 : 8185-8189. 1992
|