Citations for
1AGTR2
Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity.
Nag S, Patel S, Mani S, Hussain T.
Mol Cell Biochem 461(1-2):195-204. doi: 10.1007/s11010-019-03602-y. Epub 2019 Aug 14. 2019
2AGTR2
AT2 receptor stimulation inhibits phosphate-induced vascular calcification.
Kukida M, Mogi M, Kan-No H, Tsukuda K, Bai HY, Shan BS, Yamauchi T, Higaki A, Min LJ, Iwanami J, Okura T, Higaki J, Horiuchi M.
Kidney Int 95(1):138-148. doi: 10.1016/j.kint.2018.07.028. Epub 2018 Nov 12. 2019
3AGTR2
The angiotensin II type 2 receptors protect renal tubule mitochondria in early stages of diabetes mellitus.
Micakovic T, Papagiannarou S, Clark E, Kuzay Y, Abramovic K, Peters J, Sticht C, Volk N, Fleming T, Nawroth P, Hammes HP, Alenina N, Gröne HJ, Hoffmann SC.
Kidney Int 94(5):937-950. doi: 10.1016/j.kint.2018.06.006. Epub 2018 Sep 4. 2018
4AGTR2
Macrophage angiotensin II type 2 receptor triggers neuropathic pain.
Shepherd AJ, Mickle AD, Golden JP, Mack MR, Halabi CM, de Kloet AD, Samineni VK, Kim BS, Krause EG, Gereau RW 4th, Mohapatra DP.
Proc Natl Acad Sci U S A 115(34):E8057-E8066. doi: 10.1073/pnas.1721815115. Epub 2018 Aug 6. 2018
5AGTR2
Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain.
Shepherd AJ, Copits BA, Mickle AD, Karlsson P, Kadunganattil S, Haroutounian S, Tadinada SM, de Kloet AD, Valtcheva MV, McIlvried LA, Sheahan TD, Jain S, Ray PR, Usachev YM, Dussor G, Krause EG, Price TJ, Gereau RW 4th, Mohapatra DP.
J Neurosci 38(32):7032-7057. doi: 10.1523/JNEUROSCI.3542-17.2018. Epub 2018 Jul 5. 2018
6AGTR2
Roles of angiotensin II type 2 receptor in mice with fetal growth restriction.
Yamauchi T, Mogi M, Kan-No H, Shan BS, Higaki A, Min LJ, Higaki T, Iwanami J, Ishii EI, Horiuchi M.
Hypertens Res 41(3):157-164. doi: 10.1038/s41440-017-0004-2. Epub 2018 Jan 15. 2018
7AGTR2
Angiotensin II type 2 receptor (AT2R) as a novel modulator of inflammation in rheumatoid arthritis synovium.
Terenzi R, Manetti M, Rosa I, Romano E, Galluccio F, Guiducci S, Ibba-Manneschi L, Matucci-Cerinic M.
Sci Rep 7(1):13293. doi: 10.1038/s41598-017-13746-w. 2017
8AGTR2
Angiotensin II type 2 receptor promotes apoptosis and inhibits angiogenesis in bladder cancer.
Pei N, Mao Y, Wan P, Chen X, Li A, Chen H, Li J, Wan R, Zhang Y, Du H, Chen B, Jiang G, Xia M, Sumners C, Hu G, Gu D, Li H.
J Exp Clin Cancer Res 36(1):77. doi: 10.1186/s13046-017-0542-0. 2017
9AGTR1, AGTR2
Structural basis for selectivity and diversity in angiotensin II receptors.
Zhang H, Han GW, Batyuk A, Ishchenko A, White KL, Patel N, Sadybekov A, Zamlynny B, Rudd MT, Hollenstein K, Tolstikova A, White TA, Hunter MS, Weierstall U, Liu W, Babaoglu K, Moore EL, Katz RD, Shipman JM, Garcia-Calvo M, Sharma S, Sheth P, Soisson SM, Stevens RC, Katritch V, Cherezov V.
Nature 544(7650):327-332. doi: 10.1038/nature22035. Epub 2017 Apr 5. 2017
10AGTR2
Nociceptor-like rat dorsal root ganglion neurons express the angiotensin-II AT2 receptor throughout development.
Benitez S, Seltzer A, Acosta C.
Int J Dev Neurosci 56:10-17. doi: 10.1016/j.ijdevneu.2016.11.001. Epub 2016 Nov 4. 2017
11AGTR1, AGTR2, IRF1
Interferon regulatory factor 1 attenuates vascular remodeling; roles of angiotensin II type 2 receptor.
Nakaoka H, Mogi M, Suzuki J, Kan-No H, Min LJ, Iwanami J, Horiuchi M.
J Am Soc Hypertens 10(10):811-818. doi: 10.1016/j.jash.2016.07.005. Epub 2016 Aug 4. 2016
12AGTR1, AGTR2
Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration.
Valenzuela R, Costa-Besada MA, Iglesias-Gonzalez J, Perez-Costas E, Villar-Cheda B, Garrido-Gil P, Melendez-Ferro M, Soto-Otero R, Lanciego JL, Henrion D, Franco R, Labandeira-Garcia JL.
Cell Death Dis 7(10):e2427. doi: 10.1038/cddis.2016.327. 2016
13AGTR2
Deletion of angiotensin II type 2 receptor accelerates adipogenesis in murine mesenchymal stem cells via Wnt10b/beta-catenin signaling.
Matsushita K, Wu Y, Pratt RE, Dzau VJ.
Lab Invest 96(8):909-17. doi: 10.1038/labinvest.2016.66. Epub 2016 Jun 13. 2016
14AGTR2, TGFBR2
Angiotensin II Type 2 Receptor Decreases Transforming Growth Factor-β Type II Receptor Expression and Function in Human Renal Proximal Tubule Cells.
Guo HL, Liao XH, Liu Q, Zhang L.
PLoS One 11(2):e0148696. doi: 10.1371/journal.pone.0148696. eCollection 2016. 2016
15AGTR1, AGTR2
Attenuation of ligand-induced activation of angiotensin II type 1 receptor signaling by the type 2 receptor via protein kinase C.
Inuzuka T, Fujioka Y, Tsuda M, Fujioka M, Satoh AO, Horiuchi K, Nishide S, Nanbo A, Tanaka S, Ohba Y.
Sci Rep 6:21613. doi: 10.1038/srep21613. 2016
16AGTR2
Angiotensin II type 2 receptor is expressed in human sperm cells and is involved in sperm motility.
Gianzo M, Muñoa-Hoyos I, Urizar-Arenaza I, Larreategui Z, Quintana F, Garrido N, Subirán N, Irazusta J.
Fertil Steril 105(3):608-616. doi: 10.1016/j.fertnstert.2015.11.004. Epub 2015 Nov 23. 2016
17AGTR2
Angiotensin II type 2 receptor signaling affects dopamine levels in the brain and prevents binge eating disorder.
Nakaoka H, Mogi M, Kan-No H, Tsukuda K, Ohshima K, Wang XL, Chisaka T, Bai HY, Shan BS, Kukida M, Iwanami J, Horiuchi M.
J Renin Angiotensin Aldosterone Syst 16(4):749-57. doi: 10.1177/1470320315573680. Epub 2015 Mar 9. 2015
18AGTR2
Angiotensin type 2 receptor signaling in satellite cells potentiates skeletal muscle regeneration.
Yoshida T, Huq TS, Delafontaine P.
J Biol Chem 289(38):26239-48. doi: 10.1074/jbc.M114.585521. Epub 2014 Aug 11. 2014
19AGTR2
Role of inflammation and the angiotensin type 2 receptor in the regulation of arterial pressure during pregnancy in mice.
Mirabito KM, Hilliard LM, Wei Z, Tikellis C, Widdop RE, Vinh A, Denton KM.
Hypertension 64(3):626-31. doi: 10.1161/HYPERTENSIONAHA.114.03189. Epub 2014 Jun 16. 2014
20AGTR1, AGTR2
Association of angiotensin II type I and type II receptor genes polymorphisms with the presence of premature coronary disease and metabolic syndrome.
Abd El-Aziz TA, Mohamed RH, Rezk NA.
Mol Biol Rep 41(2):1027-33. doi: 10.1007/s11033-013-2947-y. Epub 2014 Jan 3. 2014
21AGTR2
Angiotensin II type 2 receptor regulates the development of pancreatic endocrine cells in mouse embryos.
Leung KK, Liang J, Zhao S, Chan WY, Leung PS.
Dev Dyn 243(3):415-27. doi: 10.1002/dvdy.24084. Epub 2013 Nov 23. 2014
22AGTR2, ARHGEF6, MAGT1, MAOA, NXF5, SRPX2, ZNF41, ZNF674
XLID-causing mutations and associated genes challenged in light of data from large-scale human exome sequencing.
Piton A, Redin C, Mandel JL.
Am J Hum Genet 93(2):368-83. doi: 10.1016/j.ajhg.2013.06.013. Epub 2013 Jul 18. Erratum in: Am J Hum Genet. 2013 Aug 8;93(2):406. 2013
23AGTR2
Angiotensin II type 2 receptor (AT2R) is associated with increased tolerance of the hyperthyroid heart to ischemia-reperfusion.
Tavares FM, da Silva IB, Gomes DA, Barreto-Chaves ML.
Cardiovasc Drugs Ther 27(5):393-402. doi: 10.1007/s10557-013-6473-x. 2013
24AGTR2
Angiotensin AT(2) receptor contributes towards gender bias in weight gain.
Samuel P, Khan MA, Nag S, Inagami T, Hussain T.
PLoS One 8(1):e48425. doi: 10.1371/journal.pone.0048425. Epub 2013 Jan 15. 2013
25AGTR2
Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca2+ currents in NTS neurons.
Wang G, Coleman CG, Glass MJ, Zhou P, Yu Q, Park L, Anrather J, Pickel VM, Iadecola C.
Am J Physiol Regul Integr Comp Physiol 302(9):R1076-83. doi: 10.1152/ajpregu.00571.2011. Epub 2012 Feb 29. 2012
26AGTR1, AGTR2
Angiotensin II modulates VEGF-driven angiogenesis by opposing effects of type 1 and type 2 receptor stimulation in the microvascular endothelium.
Carbajo-Lozoya J, Lutz S, Feng Y, Kroll J, Hammes HP, Wieland T.
Cell Signal 24(6):1261-9. Epub 2012 Feb 20. 2012
27AGTR2
Moderate cardiac-selective overexpression of angiotensin II type 2 receptor protects cardiac functions from ischaemic injury.
Qi Y, Li H, Shenoy V, Li Q, Wong F, Zhang L, Raizada MK, Sumners C, Katovich MJ.
Exp Physiol 97(1):89-101. Epub 2011 Oct 3. 2012
28AGTR2
Impact of AT2 receptor deficiency on postnatal cardiovascular development.
Biermann D, Heilmann A, Didié M, Schlossarek S, Wahab A, Grimm M, Römer M, Reichenspurner H, Sultan KR, Steenpass A, Ergün S, Donzelli S, Carrier L, Ehmke H, Zimmermann WH, Hein L, Böger RH, Benndorf RA.
PLoS One 7(10):e47916. doi: 10.1371/journal.pone.0047916. Epub 2012 Oct 29. 2012
29AGTR1, AGTR2
Identification and characterization of a functional mitochondrial angiotensin system.
Abadir PM, Foster DB, Crow M, Cooke CA, Rucker JJ, Jain A, Smith BJ, Burks TN, Cohn RD, Fedarko NS, Carey RM, O'Rourke B, Walston JD.
Proc Natl Acad Sci U S A 108(36):14849-54. Epub 2011 Aug 18. 2011
30AGTR1, AGTR2
Angiotensin II receptors modulate muscle microvascular and metabolic responses to insulin in vivo.
Chai W, Wang W, Dong Z, Cao W, Liu Z.
Diabetes 60(11):2939-46. Epub 2011 Sep 6. 2011
31AGTR2
Effect of angiotensin II type 2 receptor deletion in hematopoietic cells on brain ischemia-reperfusion injury.
Iwanami J, Mogi M, Tsukuda K, Min LJ, Sakata A, Jing F, Ohshima K, Horiuchi M.
Hypertension 58(3):404-9. Epub 2011 Jul 18. 2011
32AGTR2
Purkinje cells express Angiotensin II AT(2) receptors at different developmental stages.
Arce ME, Sánchez SI, Aguilera FL, Seguin LR, Seltzer AM, Ciuffo GM.
Neuropeptides 45(1):69-76. Epub 2010 Dec 10. 2011
33AGTR1, AGTR2
Expression of AT1R, AT2R and AT4R and their roles in extravillous trophoblast invasion in the human.
Williams PJ, Mistry HD, Innes BA, Bulmer JN, Pipkin FB.
Placenta 31(5):448-55. Epub 2010 Mar 20.PMID: 20304486 2010
34AGTR1, AGTR2
Direct angiotensin II type 2 receptor stimulation decreases dopamine synthesis in the rat striatum.
Mertens B, Vanderheyden P, Michotte Y, Sarre S.
Neuropharmacology 58(7):1038-44. Epub 2010 Jan 26.PMID: 20097214 2010
35AGTR2
Maternal protein restriction reduces angiotensin II AT(1) and AT(2) receptor expression in the fetal rat kidney.
Alwasel SH, Kaleem I, Sahajpal V, Ashton N.
Kidney Blood Press Res 33(4):251-9. Epub 2010 Jul 2. 2010
36AGT, AGTR1, AGTR2
Neuronal and glial cell expression of angiotensin II type 1 (AT1) and type 2 (AT2) receptors in the rat retina.
Downie LE, Vessey K, Miller A, Ward MM, Pianta MJ, Vingrys AJ, Wilkinson-Berka JL, Fletcher EL.
Neuroscience 161(1):195-213. Epub 2009 Mar 17.PMID: 19298848 2009
37AGTR2
Over-expression of angiotensin II type 2 receptor (agtr2) decreases collagen accumulation in atherosclerotic plaque.
Dandapat A, Hu CP, Chen J, Liu Y, Khan JA, Remeo F, Carey RM, Hermonat PL, Mehta JL.
Biochem Biophys Res Commun 366(4):871-7. Epub 2007 Nov 26. 2008
38AGTR2, NR1H4
FXR-mediated regulation of angiotensin type 2 receptor expression in vascular smooth muscle cells.
Zhang Q, He F, Kuruba R, Gao X, Wilson A, Li J, Billiar TR, Pitt BR, Xie W, Li S.
Cardiovasc Res 77(3):560-9. Epub 2007 Nov 13.PMID: 18006431 2008
39AGTR2
The angiotensin II receptor 2 is expressed and mediates angiotensin II signaling in lung fibrosis.
Kšnigshoff M, Wilhelm A, Jahn A, Sedding D, Amarie OV, Eul B, Seeger W, Fink L, GŸnther A, Eickelberg O, Rose F.
Am J Respir Cell Mol Biol 37(6):640-50. Epub 2007 Jul 13. 2007
40AGTR2, MRX88
AGTR2 in brain development and function.
Vervoort VS, Guzauskas G, Archie J, Schwartz CE, Stevenson RE, Srivastava AK.
Am J Med Genet A 140(5):419-20. No abstract available. 2006
41ACSL4, AFF2, AGTR2, ARHGEF6, ARX, ATRX, DLG3, ESMR, FTSJ1, GDI1, IL1RAPL1, KDM5C, MECP2, MRX68, MRX89, MRX90, MRXS31, NLGN3, NLGN4X, OPHN1, PQBP1, RPS6KA3, RTTM, SLC16A2, SLC6A8, SYN1, TSPAN7, ZNF41
X linked mental retardation: a clinical guide.
Raymond FL.
J Med Genet 43(3):193-200. Epub 2005 Aug 23. 2006
42AGTR1, RTD3, AGTR2
Angiotensin II regulates phosphoinositide 3 kinase/Akt cascade via a negative crosstalk between AT1 and AT2 receptors in skin fibroblasts of human hypertrophic scars.
Liu HW, Cheng B, Yu WL, Sun RX, Zeng D, Wang J, Liao YX, Fu XB.
Life Sci 79(5):475-83. Epub 2006 Mar 7. 2006
43AGTR2
The AT2 gene may have a gender-specific effect on kidney function and pulse pressure in type I diabetic patients.
Pettersson-Fernholm K, Frojdo S, Fagerudd J, Thomas MC, Forsblom C, Wessman M, Groop PH; FinnDiane Study Group.
Kidney Int 69(10):1880-4. 2006
44ACE, ACE2, AGTR2, AGTR1
Angiotensin-converting enzyme 2 protects from severe acute lung failure.
Imai Y, Kuba K, Rao S, Huan Y, Guo F, Guan B, Yang P, Sarao R, Wada T, Leong-Poi H, Crackower MA, Fukamizu A, Hui CC, Hein L, Uhlig S, Slutsky AS, Jiang C, Penninger JM.
Nature 436(7047):112-6. 2005
45AGTR2
Sequence variations in AGTR2 are unlikely to be associated with X-linked mental retardation.
Huang D, Sun W, Strom CM.
Am J Med Genet A 139A(3):243-244. 2005
46AGTR2, CNKSR1
The scaffold protein CNK1 interacts with the angiotensin II type 2 receptor.
Fritz RD, Radziwill G.
Biochem Biophys Res Commun 338(4):1906-12. Epub 2005 Nov 9. 2005
47MRX88, AGTR2
Identification of two AGTR2 mutations in male patients with non-syndromic mental retardation.
Ylisaukko-Oja T, Rehnstrom K, Vanhala R, Tengstrom C, Lahdetie J, Jarvela I I.
Hum Genet 114(2):211-213. Epub 2003 Nov 04. 2004
48AGTR1, AGTR2
Haplotypes of the angiotensin II receptor genes AGTR1 and AGTR2 in women with normotensive pregnancy and women with preeclampsia.
Plummer S, Tower C, Alonso P, Morgan L, Baker P, Broughton-Pipkin F, Kalsheker N.
Hum Mutat 24(1):14-20. 2004
49AGTR2
AGTR2 mutations in X-linked mental retardation.
Vervoort VS, Beachem MA, Edwards PS, Ladd S, Miller KE, de Mollerat X, Clarkson K, DuPont B, Schwartz CE, Stevenson RE, Boyd E, Srivastava AK.
Science 296(5577):2401-3. 2002
50AGTR1, AGTR2
Molecular biology and signaling of angiotensin receptors: an overview.
Inagami T.
J Am Soc Nephrol 10 Suppl 11:S2-7. Review. 1999
51AGTR1, AGTR2
Localization of angiotensin AT1 and AT2 receptors.
Allen AM, et al.
J Am Soc Nephrol 10 Suppl 11:S23-9. Review. 1999
52AGTR2
Efficient transcription of the human angiotensin II type 2 receptor gene requires intronic sequence elements.
Warnecke C, et al.
Biochem J 340 ( Pt 1):17-24. 1999
53AGTR1, AGTR2
Genetic deletion and overexpression of angiotensin II receptors.
Hein L.
J Mol Med 76 : 756-763. 1998
54AGTR2
Genomic organization and polymorphism of human angiotensin II type 2 receptor : no evidence for its gene mutation in two families of human premature ovarian failure syndrome.
Katsuya T, et al.
Mol Cell Endocrinol 127 : 221-228. 1997
55AGTR1, AGTR2
Molecular biology of angiotensin receptors and their role in human cardiovascular disease.
Regitz-Zagrosek V, et al.
J Mol Med 74 : 233-251. 1996
56AGTR2, MRX35, MRX88
Localisation of a new gene for non-specific mental retardation to Xq22-q26 (MRX35).
Gu XX, Decorte R, Marynen P, Fryns JP, Cassiman JJ, Raeymaekers P.
J Med Genet 33(1):52-5. 1996
57AGTR2
Assignment of the human angiotensin II type 2 receptor gene (AGTR2) to chromosome Xq22-q23 by fluorescence in situ hybridization.
Chassagne C, et al.
Genomics 25 : 601-603. 1995
58AGTR2
Molecular cloning of the human angiotensin II type 2 receptor cDNA.
Martin MM, et al.
Biochem Biophys Res Commun 205 : 645-651. 1994
59AGTR2
Human type 2 angiotensin II receptor gene : cloned, mapped to the X chromosome, and its mRNA is expressed in the human lung.
Koike G, et al.
Biochem Biophys Res Commun 203 : 1842-1850. 1994
60AGTR2
Molecular characterization and chromosome localization of a human angiotensin II AT2 receptor gene highly expressed in fetal tissues.
Lazard D, et al.
Receptors Channels 2 : 271-280. 1994
61AGTR2
Expression cloning of type 2 angiotensin II receptor reveals a unique class of seven-transmembrane receptors.
Mukoyama M, et al.
J Biol Chem 268 : 24539-24542. 1993
62AGTR2
Molecular cloning of a novel angiotensin II receptor isoform involved in phosphotyrosine phosphatase inhibition.
Kambayashi Y, et al.
J Biol Chem 268 : 24543-24546. 1993